A Case Report of Membranoproliferative Glomerulonephritis: Infection‐Related or Immune‐Related? by Ayman Azhary, Mohammed Taha, Nooh Mohamed Hajhamed, Salahaldeen Ismail Mohammed, Nouh Saad Mohamed, Waleed Azhary Sir Alkhatim

“…Nevertheless, following renal biopsy, which revealed an MPGN pattern, and immunohistochemistry, which revealed a full house picture, we conducted a second ANA test using the more sensitive/broader spectrum IFA hep2 cell test, which showed a coarse speckled nuclear pattern with a significant titer (1/1000), as well as a negative line blot assay test using 15 distinct antigens. Following the modification of our diagnosis to lupus nephritis, the patient responded fairly well once we started him on an immunosuppressive drug. …”
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Autoantibodies to Zinc Transporter 8 and SLC30A8 Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa by Raouia Fakhfakh, Sana Kmiha, Safa Tahri, Sawsan Feki, Ferjeni Zouidi, Olfa Abida, Mongia Hachicha, Thouraya Kammoun, Hatem Masmoudi

“…In addition to classical autoantibodies (Abs) to islet cell antigens, antizinc transporter 8 Abs (ZnT8-Ab) have been recently described in T1D. …”
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In Vivo Bioluminescence Visualization of Antitumor Effects by Human MUC1 Vaccination by Yong Hyun Jeon, Yun Choi, Hyun Joo Kim, Joo Hyun Kang, Chul Woo Kim, Jae Min Jeong, Dong Soo Lee, June-Key Chung

“…Recently, the use of a cancer deoxyribonucleic acid (DNA) vaccine encoding tumor-associated antigens has emerged as an immunotherapeutic strategy. …”
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Properties of Actinobacillus pleuropneumoniae isolates by V. А. Evgrafova, О. V. Pruntova, N. B. Shadrova, А. М. Timina

“…Results of tests of six Actinobacillus pleuropneumoniae isolates recovered from the diseased pigs kept in animal holdings located in the Russian Federation for their biological properties (biochemical, proteomic, antigenic and pathogenic ones) are presented in the paper. …”
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Parasite-Specific IL-17-Type Cytokine Responses and Soluble IL-17 Receptor Levels in Alveolar Echinococcosis Patients by Christian J. Lechner, Beate Grüner, Xiangsheng Huang, Wolfgang H. Hoffmann, Peter Kern, Peter T. Soboslay

“…Similarly, the cellular production of lL-17F and slL-L7RA in response to E. multilocularis antigens was low in AE patients, while levels of slL-17RB were highly enhanced. …”
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Clinical efficacy studies of the vaccine against feline panleukopenia, calicivirus infection and viral rhinotracheitis Carnifel PCH in kittens by T. S. Galkina, A. A. Komarova, A. M. Kiselev

“…Due to variety of antigenically different FCV strains, the use of the vaccines containing two or more viral strains may induce a broader heterologous protection. …”
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Development of IgY-Based Sandwich ELISA as a Robust Tool for Rapid Detection and Discrimination of Toxigenic Vibrio cholerae by Mahdiye Bayat, Alireza Khabiri, Behzad Hemati

“…This study aimed to introduce two sensitive sandwich ELISAs based on avian antibodies (IgY) targeting outer membrane protein W (OmpW) and cytotoxin B (CtxB) antigens of V. cholerae. Methods. The sequences of ompW and ctxB genes were cloned into pET28a vector. …”
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Comparisons of CVID and IgGSD: Referring Physicians, Autoimmune Conditions, Pneumovax Reactivity, Immunoglobulin Levels, Blood Lymphocyte Subsets, and HLA-A and -B Typing in 432 Ad... by James C. Barton, Luigi F. Bertoli, J. Clayborn Barton

“…Common variable immunodeficiency (CVID) and immunoglobulin (Ig) G subclass deficiency (IgGSD) are heterogeneous disorders characterized by respiratory tract infections, selective Ig isotype deficiencies, and impaired antibody responses to polysaccharide antigens. Using univariable analyses, we compared observations in 34 CVID and 398 IgGSD adult index patients (81.9% women) referred to a hematology/oncology practice. …”
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Vaccine-induced reduction of COVID-19 clusters in school settings in Japan during the epidemic wave caused by B.1.1.529 (Omicron) BA.2, 2022 by Yuta Okada, Hiroshi Nishiura

“…Our results also suggest that antigenically updated vaccines that are more effective against the variant responsible for the ongoing epidemic may greatly help decrease not only the incidence but also the unnecessary loss of learning opportunities among school-age students.…”
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Polygenic risk score for acute rejection based on donor-recipient non-HLA genotype mismatch. by Rui Cao, David P Schladt, Casey Dorr, Arthur J Matas, William S Oetting, Pamala A Jacobson, Ajay Israni, Jinbo Chen, Weihua Guan

“…To reduce the risk of post-transplant AR, determination of kidney transplant donor-recipient mismatching focuses on blood type and human leukocyte antigens (HLA), while it remains unclear whether non-HLA genetic mismatching is related to post-transplant complications.…”
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Dengue Infection and Its Relationship with Evans Syndrome: A Pediatric Case by Ivan Jose Ardila Gomez, Pilar Pérez López, Mónika Rocío Hernández Carreño, Juan Camilo Barrios Torres

“…Mechanisms have been described by which an exacerbated response of the disease is triggered through the increase of infected cells, formation of immune complexes, and complement pathway activation, which lead to a cross-reaction of viral antigens with epithelial cells with platelets with subsequent endothelial dysfunction and bleeds. …”
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Nanomechanical characterization of soft nanomaterial using atomic force microscopy by Chi-Dat Lam, Soyeun Park

“…Additionally, the establishment of physical or chemical bonds during indentation experiments, observable in retract f-d curves, is crucial for the adhesive properties of samples and binding affinity between antibodies (receptors) and antigens (ligands). Chemical force microscopy, single-molecule force spectroscopy, and single-cell force spectroscopy are primary AFM methods that provide a comprehensive view of such properties through retract curve analysis.Furthermore, this paper, structured into key thematic sections, also reviews the exemplary application of AFM across multiple scientific disciplines. …”
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TIM-3 and TIM-1 Could Regulate Decidual γδTCR Bright T Cells during Murine Pregnancy by Jasper Nörenberg, Matyas Meggyes, Pal Jakso, Eva Miko, Aliz Barakonyi

“…Pregnancy is an immunological enigma where paternal antigens are present at the fetomaternal interface. …”
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Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

“…This study supports the production of functionally active clinical grade (IMP) recombinant IgE and paves the way for the development of a new therapeutic antibody class for a range of antigenic specificities and disease settings.…”
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The case for development of a core outcome set (COS) and supplemental reporting guidelines for influenza vaccine challenge trial research in swine by Sheila Keay, Famke Alberts, Annette M. O’Connor, Robert Friendship, Terri O’Sullivan, Zvonimir Poljak

“…The checklist serves two purposes: as a reminder of details essential to report for inclusion of findings in meta-analyses and sub-group meta-analyses (e.g., antigenic or genomic descriptions of influenza vaccine and challenge viruses), and as an aid to help synthesis researchers fully characterize and comprehensively include studies in reviews.…”
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CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report by M. Niedźwiecki, O. Budziło, M. Zieliński, E. Adamkiewicz-Drożyńska, L. Maciejka-Kembłowska, T. Szczepański, P. Trzonkowski

“…By analyzing Treg subpopulations, it was shown that only memory Tregs in contact with leukemic antigens showed statistically significant differences. …”
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Adenoviral Vector-Based Vaccine Expressing Hemagglutinin Stem Region with Autophagy-Inducing Peptide Confers Cross-Protection Against Group 1 and 2 Influenza A Viruses by Wen-Chien Wang, Ekramy E. Sayedahmed, Marwa Alhashimi, Ahmed Elkashif, Vivek Gairola, Muralimanohara S. T. Murala, Suryaprakash Sambhara, Suresh K. Mittal

“…<b>Methods:</b> In this study, bovine and human adenoviral vector-based vaccine platforms were utilized to express various combinations of antigens. These included the H5N1 hemagglutinin (HA) stem region or HA2, the extracellular domain of matrix protein 2 of influenza A virus, HA signal peptide (SP), trimerization domain, excretory peptide, and the autophagy-inducing peptide C5 (AIP-C5). …”
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Newcastle Disease Virus Displaying an Ectodomain of Middle East Respiratory Syndrome Coronavirus Spike Protein Elicited Robust Humoral and Cellular Immunity in Mice by Jaturawitt Prasopsiri, Kanjana Srisutthisamphan, Benjamas Liwnaree, Juggragarn Jengarn, Jarin Kramyu, Payuda Hansoongnern, Papon Muangsanit, Nathiphat Tanwattana, Challika Kaewborisuth, Suttipun Sungsuwan, Anan Jongkaewwattana, Nanchaya Wanasen

“…With recent advancements in stabilizing coronavirus spike proteins to enhance their antigenicity, this study aimed to determine whether modifications to the MERS-CoV spike protein could improve its presentation on NDV particles, allowing the resulting virus to be used as an inactivated vaccine. …”
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Rational design of a triple-type HPV53/56/66 vaccine with one preferable base particle incorporating two identified immunodominant sites by Ciying Qian, Jie Chen, Yurou Yang, Yihan Lu, Tianyu Ren, Yanan Jiang, Yang Huang, Xin Chi, Shuyue Zhang, Chengzong Zhang, Kewei Li, Jingjia Shen, Sibo Zhang, Daning Wang, Lizhi Zhou, Tingting Li, Qingbing Zheng, Hai Yu, Ying Gu, Ningshao Xia, Shaowei Li

“…This research outlines an amenable way to simultaneously identify immunodominant sites and their preferable particle base context for cross-type vaccine design, thereby offering a paradigm as extending antigenic variety in single particle to broaden vaccine protection coverage. …”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages by Diana Martínez-Saucedo, Juan de Dios Ruíz-Rosado, César Terrazas, Blanca E. Callejas, Abhay R. Satoskar, Santiago Partida-Sánchez, Luis I. Terrazas

“…Our previous studies indicate that Taenia crassiceps-excreted/secreted antigens (TcES) downregulate inflammatory responses in rodent models of autoimmune diseases, by promoting the generation of alternatively activated-like macrophages (M2) in vivo. …”
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