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2241
Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis?
Published 2013-01-01“…The finding of highly specific antibodies directed against onconeural antigens has revolutionized the diagnosis and promoted the understanding of these syndromes and led to the current hypothesis of an autoimmune pathophysiology. …”
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2242
Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria
Published 2025-01-01“…Abstract Protective immunity to malaria depends on acquisition of parasite-specific antibodies, with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) being one of the most important target antigens. The effector functions of PfEMP1-specific IgG include inhibition of infected erythrocyte (IE) sequestration and opsonization of IEs for cell-mediated destruction. …”
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2243
Autoantibodies in systemic sclerosis: From disease bystanders to pathogenic players
Published 2025-06-01“…Recent studies have expanded knowledge through the discovery of new antigenic targets, advanced methods for measuring Aab levels, and understanding their possible pathogenic roles in AID. …”
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2244
Early-Onset Chronic Inflammatory Disease Associated with Maternal Microchimerism
Published 2012-01-01“…Although HLA typing revealed no noninherited maternal antigens in lymphocytes, female cells were demonstrated in the patient’s skin and lymph nodes, suggesting that maternal microchimerism might be involved in the pathogenesis of fever without source in infants.…”
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2245
The Role of Sulfatides in Liver Health and Disease
Published 2025-01-01“…Sulfatides are self-lipid antigens presented by cholangiocytes to activate cluster of differentiation 1d (CD1d)-restricted type II natural killer T (NKT) cells. …”
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2246
A Review of the Progress in the Development of Leishmaniasis Vaccines
Published 2024-07-01“…Numerous studies have been conducted on various vaccines utilizing live attenuated parasites, killed parasites, subunit antigens, recombinant vaccines, and DNA technology. …”
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2247
Rituximab for Autoimmune Encephalitis with Epilepsy
Published 2020-01-01“…It is characterized by antibodies against cerebral antigens, such as potassium channels such as leucine-rich, glioma inactivated 1 (LGI1) and contactin-associated protein 2 (CASPR2), calcium channels such as the voltage-gated calcium channel (VGCC), or neurotransmitter receptors such as the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), gamma aminobutyric acid receptor (GABAR), and N-methyl-D-aspartate receptor (NMDAR). …”
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2248
Computer-Aided Design of an Epitope-Based Vaccine against Epstein-Barr Virus
Published 2017-01-01“…The T cell component includes 14 CD8 T cell epitopes from early antigens and 4 CD4 T cell epitopes, targeted during the course of a natural infection and providing a population protection coverage of over 95% and 81.8%, respectively. …”
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2249
Risk of infections in bispecific antibody therapy for multiple myeloma: a comprehensive review of literature
Published 2025-12-01“…Bispecific antibodies have emerged as a significant advancement in MM treatment, offering high effectiveness and specificity by targeting different antigens such as BCMA, CD38, and FcRH5. However, the risk of infection poses a major challenge in MM patients, which is thought to be influenced by various factors.The overall risk of infections associated with the use of BsAbs is estimated to be approximately 56% for all grades, with Grade 3/4 infections accounting for 24% of cases. …”
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2250
ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics
Published 2021-01-01“…The COVID-19 pandemic that began in late 2019 continues with new challenges arising due to antigenic drift as well as individuals who cannot or choose not to take the vaccine. …”
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2251
Detection of bovine coronavirus (bcov) infection in cattle with clinical respiratory signs by pcr and investigation of the serological status of these animals
Published 2023-12-01“…<b>Aim: </b>It was aimed to reveal the antigenic and serological prevalence of bovine coronavirus (BCoV) in cattle with clinically respiratory infection and to evaluate the relationship between virus shedding and serological status of animals in this study.…”
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2252
CALENDARIO POLÍNICO DE ESPECIES POTENCIALMENTE ALERGÓGENAS Y SU RELACIÓN CON PARÁMETROS METEOROLÓGICOS EN VILLA VENTANA, PROVINCIA DE BUENOS AIRES
Published 2014-12-01“…If a plant contains antigens capable of triggering an anaphylactic phenomenon in the human body it must be considered allergenic. …”
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2253
Canine parvovirus enteritis: epidemic situation analysis and perspectives
Published 2021-01-01“…One of the main biological properties of parvovirus is its continuous genetic evolution, which led to the replacement of the original virus type by new antigenic variants – CPV-2a, CPV-2b and CPV-2c. According to the literature data, all three variants of the virus are currently circulating in the domestic dog population worldwide. …”
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2254
Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine
Published 2014-01-01“…High mutation rate in the viral genome underlying the antigenic variability of the viral proteome is the major hindrance as far as the antibody based vaccine development is concerned. …”
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2255
Monocyte Subsets in Schistosomiasis Patients with Periportal Fibrosis
Published 2014-01-01“…A major issue with Schistosoma mansoni infection is the development of periportal fibrosis, which is predominantly caused by the host immune response to egg antigens. Experimental studies have pointed to the participation of monocytes in the pathogenesis of liver fibrosis. …”
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2256
HIFU-CCL19/21 Axis Enhances Dendritic Cell Vaccine Efficacy in the Tumor Microenvironment
Published 2025-01-01“…Methods: M-HIFU was applied to induce immunogenic cell death by mechanically disrupting tumor cells, releasing tumor-associated antigens and creating an immunostimulatory environment. …”
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2257
Gamma delta T cells in acute myeloid leukemia: biology and emerging therapeutic strategies
Published 2024-02-01“…These cells represent a minor population of T lymphocytes with intrinsic abilities to recognize antigens in a major histocompatibility complex-independent manner and functionally straddle the innate and adaptive immunity interface. …”
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2258
Leptospira and Inflammation
Published 2012-01-01“…Although the virulence factors, molecular targets, mechanisms of inflammation, and signaling pathways triggered by leptospiral antigens have been studied, some questions are still unanswered. …”
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2259
Comparison of Gene Expression in Human Embryonic Stem Cells, hESC-Derived Mesenchymal Stem Cells and Human Mesenchymal Stem Cells
Published 2011-01-01“…Transcript analysis of membrane antigens suggests that IL1R1low, BMPR1Blow, FLT4low, LRRC32low, and CD34 may be good candidates for the detection and isolation of the most primitive hMSCs. …”
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2260
Simulating Immune Interference on the Effect of a Bivalent Glycoconjugate Vaccine against Haemophilus influenzae Serotypes “a” and “b”
Published 2016-01-01“…We developed a stochastic simulation model of humoral immune response to investigate the antigenic challenge of a bivalent combined glycoconjugate vaccine and a bivalent unimolecular glycoconjugate vaccine. …”
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