Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma by Haideh Namdari, Farhad Rezaei, Fatemeh Heidarnejad, Mohammad Yaghoubzad-Maleki, Maryam Karamigolbaghi

“…All vaccines comprised antigenic, nontoxic, and nonallergenic epitopes, ensuring extensive global population coverage. …”
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The problem of norovirus infection in animals (literature review) by V. А. Mischenko, A. V. Mischenko, T. B. Nikeshina, O. N. Petrova, Yu. V. Brovko, A. I. Kushlubaeva

“…Despite their high antigenicity and field effectiveness, numerous cases of diarrhea in newborn calves have been reported in a number of large livestock farms. …”
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MicroRNA-1 Inhibits the Growth of Breast Cancer Cells MDA-MB-231 and MCF-7 Treated with Hydatid Cyst Fluid by Hadis Jafari, Mahmoud Mahami-Oskouei, Adel Spotin, Behzad Baradaran, Dariush Shanehbandi, Amir Baghbanzadeh, Zahra Alizadeh

“…Antigens in hydatid cyst fluid (HCF) have been discovered to bear a significant resemblance to antigens present in cancer cells. …”
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Core-genome guided novel therapeutic targets identification and chimeric vaccine designing against Rickettsia rickettsii by Fizza Arshad, Asifa Sarfraz, Muhammad Shehroz, Umar Nishan, Asia Perveen, Riaz Ullah, Mohamed A. Ibrahim, Mohibullah Shah

“…The core genome of R. rickettsii was investigated, resulting in the identification of seven essential, human non-homologous proteins as potential drug targets, as well as four antigenic, non-allergenic proteins suitable for vaccine development. …”
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Defective expansion and function of memory like natural killer cells in HIV+ individuals with latent tuberculosis infection. by Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Siva Sai Krovvidi, Ramakrishna Vankayalapati, Vijaya Lakshmi Valluri

“…HIV infection also inhibited the expansion of memory like NK cells, production of IL-32α, IL-15 and IFN-γ in response to Mtb antigens in LTBI+ individuals.<h4>Conclusion</h4>We studied phenotypic, functional subsets and activation of memory like-NK cells during HIV infection and LTBI. …”
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Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus by Ilaria Bononi, Elisa Mazzoni, Silvia Pietrobon, Maria Rosa Iaquinta, Andrea Caselli, Elena Torreggiani, Maura Pugliatti, Ilaria Casetta, Massimiliano Castellazzi, Enrico Granieri, Fernanda Martini, Mauro Tognon

“…Experimental data indicate that patients affected by neurological diseases, including MS, are poor responders to BKPyV VP 1 antigens, thus suggesting specific immunologic dysfunctions for this polyomavirus. …”
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Developing and Activated T Cell Survival Depends on Differential Signaling Pathways to Regulate Anti-Apoptotic Bcl-xL by Ruiqing Wang, Huimin Xie, Zhaofeng Huang, Weirong Shang, Zuoming Sun

“…Upon engagement with antigens, T cells are activated and differentiated into effectors. …”
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Seroprevalence and Risk Factors of African Horse Sickness in Three Agroecological Zones of Cameroon by Mohamed M. F. Ndebé, Mohamed M. M. Mouiche, Frédéric Moffo, Rodrigue N. S. Poueme, Julius Awah-Ndukum

“…Horse sera were subjected to the ELISA blocking test for the determination of antibodies against African horse sickness virus, and positive samples were submitted to capture ELISA to determine the presence of antigens. Potential risk factors associated with AHS were assessed based on the information collected in the field. …”
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Humoral Immunity Profiling to Pandemic and Bat‐Derived Coronavirus Variants: A Geographical Comparison by Parinaz Fathi, Andrea Lucia Alfonso, Christina Yek, Zoe Putman, Matthew Drew, Dominic Esposito, Irfan Zaidi, Sophana Chea, Sokna Ly, Rathanak Sath, Chanthap Lon, Huch Chea, Rithea Leang, Rekol Huy, Sovann Ly, Heng Seng, Chee Wah Tan, Feng Zhu, Lin‐Fa Wang, Fabiano Oliveira, Kaitlyn Sadtler, Jessica Manning

“…Within SCV2 seropositive samples, 16 (50%) have higher antibody levels to antigens from the representative virus RshSTT182 versus SCV2 antigens; competitive binding ELISA assays demonstrate inhibition of reactivity to SCV2 Spike after pre‐incubation with RshSTT182 Spike. …”
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Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii by Muhammad Naveed, Amina Abid, Tariq Aziz, Ayesha Saleem, Arooj Arshad, Khushbakht Javed, Hafiz Muzzammel Rehman, Ghulam Nabi, Mitub Al-harbi, Abdullah F. Alasmari

“…Additionally, ADMET (absorption, distribution, metabolism, excretion, and toxicity) analysis was conducted to assess the pharmacokinetic properties of the compounds. Antigenicity and allergenicity of the protein show that this protein is virulent and antigenic. …”
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Clinical and pathological examinations on leptospirosis in cattle by Zabid Yener, İhsan Keleş

“…Certain diagnosis was based on the determination of leptospiral antigens by immunoperoxidase staining of sections obtained Irom liver, spleen, and kidney.…”
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HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding by Rui Zhu, Rui Zhu, Rui Zhu, Jie Wu, Ruiying Chen, Mo Zhou, Mo Zhou, Mo Zhou, Shinuo Cao, Shinuo Cao, Shinuo Cao, Zhi Wu, Zhi Wu, Zhi Wu, Ligang Wang, Lei Zhang, Shanyuan Zhu, Shanyuan Zhu, Shanyuan Zhu

“…Mutations at residue 198 of hemagglutinin (HA) are critical for antigenic variation and receptor-binding specificity, but the underlying molecular mechanisms remain unclear. …”
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Cloning and expression of African swine fever virus K205R and B602L genes inf. COLI by A. V. Scherbakov, A. S. Yakovleva, A. M. Timina, M. R. Yakupov

“…Dissolved recombinant proteins were purified by metal-chelate affinity chromatography using Ni-NTA-agarose («Qiagen»). Recombinant antigens are biologically safe, easier to prepare and ensure higher ELISA specificity. …”
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How to use monoclonal antibody-based therapy in ALL by Erica Brivio, Sujith Samarasinghe

“…Over the past decade, monoclonal antibody (MoAb)-based therapies have emerged as a promising approach to target specific antigens on leukemic cells, offering higher specificity, reduced toxicity, and improved response rates. …”
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Autoimmune pancreatitis – the special form of chronic pancreatitis by Ya. S. Tsimmerman

“…The etiology of AIP is investigated insufficiently, the role of infection (in particular, viral), antigenic damage of pancreatic ducts and acinar cells is considered. …”
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Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases by João Henrique Campos, Rodrigo Pedro Soares, Kleber Ribeiro, André Cronemberger Andrade, Wagner Luiz Batista, Ana Claudia Torrecilhas

“…Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. …”
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Frequency of Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease in Palestine by Fekri Samarah, Mahmoud A. Srour, Dirgham Yaseen, Kamal Dumaidi

“…All reported IgG alloantibodies were directed against antigens in the Rh (66.7%) and Kell (33.3%) systems. …”
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Interferon (IFN)-gamma (γ) inducible protein 10 (IP-10) in the diagnosis of latent and active tuberculosis in Bacille Calmette Guerin (BCG)-vaccinated pediatric population. by Magdalena Druszczynska, Michał Seweryn, Sebastian Wawrocki, Anna Pankowska, Anastasiia Kulbachko, Magdalena Jurczak, Magdalena Kowalewska-Pietrzak

“…The research specifically assessed IP-10 levels in serum, urine, and QuantiFERON-TB Gold Plus (QFT) cultures stimulated with M.tb antigens to determine if IP-10 could be a useful diagnostic marker for pediatric tuberculosis, either alongside or as an alternative to IFN-γ.…”
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Clinical and Pathological Roles of Ro/SSA Autoantibody System by Ryusuke Yoshimi, Atsuhisa Ueda, Keiko Ozato, Yoshiaki Ishigatsubo

“…Anti-Ro/SSA antibodies are among the most frequently detected autoantibodies against extractable nuclear antigens and have been associated with systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS). …”
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NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines by Luis E. Fernandez, Mariano R. Gabri, Marcelo D. Guthmann, Roberto E. Gomez, Silvia Gold, Leonardo Fainboim, Daniel E. Gomez, Daniel F. Alonso

“…A brief discussion on the relevance of prioritization of cancer antigens in vaccine development is also included.…”
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