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1981
Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study
Published 2025-01-01“…Age, voiding symptoms subscore, prostate-specific antigen level, median maximum flow rate, median voided volume were predictors for bladder outlet obstruction. …”
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1982
Comprehensive epidemiological evaluation of ruminant brucellosis and associated risk factors in some Egyptian Governorates
Published 2025-12-01“…The buffered acidified plate antigen test (BAPAT), Rose Bengal plate test (RBPT), and complement fixation test (CFT) were used for serological diagnosis of brucellosis. …”
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1983
Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals
Published 2025-01-01“…Two IM or IN doses of rAd5-SARS2-S1 elicited robust and sustained Th1-skewed S1-specific serum IgG, neutralizing antibodies (nAbs) against several SARS-CoV-2 variants and systemic antigen-specific memory T cell responses in mice. …”
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1984
Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus
Published 2025-01-01“…HA2, the neck of the HA protein, and M2e, the extracellular N-terminal structural domain of the M2 protein, are conserved and effective protective antigens.In this study, the HA2 sequences were fused with three M2e copies (H9N2, H1N1 and H5N1) to the norovirus VP1 protein via the SpyTag-SpyCatcher platform to form self-assembled nanoparticles and display antigenic proteins on its surface, yielding pYL262. …”
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1985
Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from...
Published 2025-02-01“…Our cohort included those with a positive SARS-CoV-2 molecular, serology or antigen test, or with a COVID-19, multisystem inflammatory disease in children, or PASC diagnosis from February 29, 2020 to August 1, 2022. …”
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1986
Acute hepatitis of non-specified etiology
Published 2011-02-01“…To estimate pathogenic and diagnostic value of detection of hepatotropic viruses components (DNA, RNA, antigens) and antiviral immune response at acute hepatitis of non-specified etiology by the methods of enzyme-linked immunoassay (EIA), polymerase chain reaction (PCR) and Т-cellular lymphocytes proliferation in response to HCV antigens stimulation.Methods. …”
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1987
Candidate vaccine construction against tick-born encephalitis based on hybrid recombinant flagG-protE-protein
Published 2018-01-01“…This indicates that the investigated recombinant protein has an antigenic structure similar to the antigenic structure of the native tickborne encephalitis virus protein E. …”
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1988
Comparative testing of vaccines based on viruses of genetic lineages G1 and Y280 for their potency against low pathogenic avian influenza H9N2
Published 2021-08-01“…It was demonstrated that due to antigenic and immunogenic differences between LPAI H9N2 strains, use of both antigenic components in the inactivated vaccines is appropriate.…”
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1989
Immunogenic Targets for Specific Immunotherapy in Multiple Myeloma
Published 2012-01-01“…Several tumor-associated antigens have been identified in patients with multiple myeloma. …”
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1990
Autoimmunity against cytokines: Double strike in autoimmune disease, a historical perspective
Published 2024-12-01“…Autoimmune responses are characterized by the development of antibodies and the activation of T lymphocytes against self-antigens. This leads to an effector immune response against tissues expressing antigens, which are later recognized by the host immune system. …”
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1991
Hypersensitivity Pneumonitis: Challenges of a Complex Disease
Published 2024-01-01“…An impressive number of inciting antigens causing hypersensitivity pneumonitis have been found to cover a wide range of occupations. …”
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1992
A Novel Insight into the Role of PLA2R and THSD7A in Membranous Nephropathy
Published 2021-01-01“…Membranous nephropathy (MN) is an organ-restricted autoimmune disease mainly caused by circulating autoantibodies against podocyte antigens, including the M-type phospholipase A2 receptor (PLA2R) and thrombospondin domain-containing 7A (THSD7A). …”
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1993
Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis.
Published 2024-01-01“…We postulated that the immune system's attack on the myelin sheath could be triggered by viruses and bacteria antigens that resemble myelin sheath components. An in-silico bioinformatics approach was undertaken in order to identify viral and bacterial antigens that resemble myelin oligodendrocyte glycoprotein (MOG) and myelin basic protein (MBP). …”
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1994
Rapid Diagnosis of Intestinal Parasitic Protozoa, with a Focus on Entamoeba histolytica
Published 2009-01-01“…Detection of specific E. histolytica antigens in stools is a fast, sensitive technique that should be considered as the method of choice. …”
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1995
Fitness costs of Mycobacterium tuberculosis resistant to rifampicin is compensated by rapid Th2 polarization mediated by early and high IL-4 production during mice infection
Published 2025-01-01“…The proteins correspond to surface antigens, virulence factors, and energy metabolism enzymes. …”
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1996
Changes Related to Age in Natural and Acquired Systemic Self-IgG Responses in Malaria
Published 2011-01-01“…Characteristic changes in systemic self-IgG-reactive repertoire were found with antigenic bands that discriminate Plasmodium falciparum infections with or without CM according to age. 8 antigenic bands distributed in MEI compared with NEC were identified while 6 other antigenic bands were distributed within MEI according to the age and clinical status. …”
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1997
Designing of an innovative conserved multiepitope subunit vaccine targeting SARS-CoV-2 glycoprotein and nucleoprotein through immunoinformatic
Published 2025-01-01“…The multi-epitope construct successfully passed three-fold toxicity, allergenicity, and antigenicity tests, affirming its non-toxic, non-allergenic, and antigenic nature. …”
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1998
Self-replicating recombinant virus-like particles of lentivirus proliferating in glioblastoma cells and normal human macrophages
Published 2024-11-01“…Inactivated vaccines are very diverse and include whole cell and acellular vaccines containing protein target antigens or nucleic acids encoding target antigens. …”
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1999
Transplantation Tolerance Induced in Humans at the Fetal or the Neonatal Stage
Published 2011-01-01“…Numerous T-cells recognizing the allogeneic, host-type antigens are identified in these patients, but these cells are anergized, following interaction with epithelial cells of the host thymus. …”
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2000
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies
Published 2016-01-01“…Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic. …”
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