Difference in Antibody Responses to Mycobacterium tuberculosis Antigens in Japanese Tuberculosis Patients Infected with the Beijing/Non-Beijing Genotype by Jingge Zhao, Beata Shiratori, Masao Okumura, Hideki Yanai, Makoto Matsumoto, Chie Nakajima, Kazue Mizuno, Kenji Ono, Tetsuya Oda, Haorile Chagan-Yasutan, Yugo Ashino, Takashi Matsuba, Takashi Yoshiyama, Yasuhiko Suzuki, Toshio Hattori

“…The plasma samples from 20 cases of Beijing and 16 cases of non-Beijing MTB infected individuals and 24 healthy controls (HCs) were collected, and antibodies against 11 antigens (Rv0679c142Asn, Rv0679c142Lys, Ag85B, Ag85A, ARC, TDM-M, TDM-K, HBHA, MDP-1, LAM, and TBGL) were measured by ELISA. …”
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Study of morphology with assessment of expression of proliferation marker Ki67 antigen and P53 protein in lesions of gall bladder by Ojasvi Ramesh, Mamta Gupta, Sanjay Kaushik, Seema Acharya, Brijesh Thakur, Aparna Bhardwaj

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Identification of TTLL8, POTEE, and PKMYT1 as immunogenic cancer-associated antigens and potential immunotherapy targets in ovarian cancer by Esen Yonca Bassoy, Remya Raja, Thomas E. Rubino, Fabian Coscia, Krista Goergen, Paul Magtibay, Kristina Butler, Alessandra Schmitt, Ann L. Oberg, Marion Curtis

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In Silico Screening of Putative Corynebacterium pseudotuberculosis Antigens and Serological Diagnosis for Caseous Lymphadenitis in Sheep by Enzyme-Linked Immunosorbent Assay by Daniela Droppa-Almeida, Caroline de Santana Ferreira, Ioná Brito, Sibele Borsuk, Jorge Alberto López Rodríguez, Isabel Bezerra Lima-Verde, Francine Ferreira Padilha

“…The expressed proteins were used as an antigen for serological diagnosis by ELISA. All proteins showed distinct immunodominant epitopes and potential antigenic characteristics. …”
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ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS by A. V. Konstantinov, S. K. Starov, V. I. Diev, N. V. Moroz, E. V. Kurnenkova, D. K. Basova, A. V. Kononov, K. Yu. Fedoseyev, V. P. Melnikov

“…The study results demonstrated tat associated as well as monovalent virus vaccines against sheep pox, goat pox and peste des petits rum^nts have good antigenic properties. The vaccination induced high level of virus neutralizing antibodies against each of the above listed diseases and ensured formation of strong immunity tat is supported by the results of tallenge of sheep with virulent sheep pox virus (“Afghanistan” strain). …”
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Antigen-Specific Tissue-Resident Memory T Cells in the Respiratory System Were Generated following Intranasal Vaccination of Mice with BCG by Qiongli Wu, Shuangpeng Kang, Jun Huang, Shunqiao Wan, Binyan Yang, Changyou Wu

“…Taken together, our data demonstrated that intranasal vaccination of mice with BCG could induce antigen-specific CD4+ and CD8+ TRM cells in the respiratory system and have the ability to provide protection against pulmonary reinfection.…”
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Systematic review on the compliance of WHO guidelines in the management of patients with advanced HIV disease in Africa: The case of cryptococcal antigen screening. by Zuhura Mbwana Ally, Jackline Vicent Mbishi, Mariam Salim Mbwana, Hafidha Mhando Bakari, Swalehe Mustafa Salim, Zarin Nudar Rodoshi, Muhidin Ibrahim Hundisa, Rebecca Mesfin Sileshi, Biruk Demisse Ayalew, Rahma Musoke, Lynn Moshi, Yousef Elias Fakhoury, Haji Mbwana Ally, Habib Omari Ramadhani

“…<h4>Background</h4>The World Health Organization (WHO) recommended cryptococcal antigen (CrAg) screening for people presenting with advanced HIV disease (AHD) and for those with positive CrAg without evidence of meningitis to initiate preemptive antifungal medication. …”
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Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade by Sinda Bigenzahn, Ines Pree, Christoph Klaus, Nina Pilat, Benedikt Mahr, Elisabeth Schwaiger, Patrick Nierlich, Friedrich Wrba, Thomas Wekerle

“…We therefore investigated the impact of minor antigen disparities on the induction of mixed chimerism and tolerance. …”
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Immunoglobulin G4-Related disease, constitutional symptoms, human leukocyte antigen b27 positivity, and sacroiliitis – Reply by S Verma, L Khurshid, P R Voleti, A N Malaviya

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Association of Cytotoxic T Lymphocyte Antigen-4 Gene Polymorphisms with Psoriasis Vulgaris: A Case-Control Study in Turkish Population by Hatice Gül Dursun, Hüseyin Osman Yılmaz, Recep Dursun, Sevsen Kulaksızoğlu

“…Cytotoxic T lymphocyte antigen-4 (CTLA-4) expressed only on activated T cells is an immunoregulatory molecule and plays a role in the pathogenesis of autoimmune disorders. …”
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Factors Requiring Adjustment in the Interpretation of Serum Carcinoembryonic Antigen: A Cross-Sectional Study of 18,131 Healthy Nonsmokers by Hae Yeon Kang, Eun Kyung Choe, Kyu Joo Park, Young Lee

“…Serum carcinoembryonic antigen (CEA) is a well-known tumor marker for colorectal adenocarcinoma. …”
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Differential regulation of the release of tumor necrosis factor-α and of eicosanoids by mast cells in rat airways after antigen challenge by Aryene Goes Trezena, Zilma Lucia da Silva, Ricardo Martins Oliveira-filho, Amilcar Sabino Damazo, Anita Hilda Straus, Helio Kiyoshi Takahashi, Sonia Maria Oliani, Wothan Tavares de Lima

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Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes by Thilde Nordmann Winther, Kari Stougaard Jacobsen, Aashiq Hussain Mirza, Ida Louise Heiberg, Claus Heiner Bang-Berthelsen, Flemming Pociot, Birthe Hogh

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Tolerance in TCR/Cognate Antigen Double-TransgenicMice Mediated by Incomplete Thymic Deletion andPeripheral Receptor Downregulation by Clio Mamalaki, Marianna Murdjeva, Mauro Tolaini, Trisha Norton, Phillip Chandler, Alain Townsend, Elizabeth Simpson, Dimitris Kioussis

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Partial Purification of Integral Membrane Antigenic Proteins from Trypanosoma evansi That Display Immunological Cross-Reactivity with Trypanosoma vivax by Norma P. Velásquez, Rocío E. Camargo, Graciela L. Uzcanga, José Bubis

“…Since the production of T. vivax antigens is a limiting factor as this parasite is difficult to propagate in experimental animal models, our goal has been to identify and isolate antigens from T. evansi that cross-react with T. vivax. …”
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Evaluation of the transmission-blocking potential of Plasmodium vivax antigen Pvg37 using transgenic rodent parasites and clinical isolates by Di Zhang, Yan Zhao, Dongyan Liu, Fei Liu, Pengbo Liu, Biying Zhang, Zifang Wu, Wanlapa Roobsoong, Sirasate Bantuchai, Sataporn Thongpoon, Piyarat Sripoorote, Meilian Wang, Liwang Cui, Yaming Cao

“…Transmission-blocking vaccines (TBVs) have shown the potential to inhibit malaria transmission by targeting antigens expressed in sexual-stage parasites. Pbg37, a conserved protein expressed in sexual stages from gametocyte to ookinete in the rodent parasite P. berghei, is a viable target for TBV development.Methods and findingsIn this study, we constructed a transgenic strain, TrPvg37Pb, expressing Pvg37 using the P. berghei ΔPbg37 strain. …”
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Meningococcal Antigen Typing System Development and Application to the Evaluation of Effectiveness of Meningococcal B Vaccine and Possible Use for Other Purposes by Alexander Domnich, Roberto Gasparini, Daniela Amicizia, Giuseppe Boccadifuoco, Marzia Monica Giuliani, Donatella Panatto

“…Development of the 4-component meningococcal serogroup B vaccine (4CMenB) has required new assays for the reliable evaluation of the expression and cross-reactivity of those specific antigen variants that are predicted to be targeted by bactericidal antibodies elicited by the vaccine in different isolates. …”
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The Association between Deoxyribonucleic Acid Hypermethylation in Intron VII and Human Leukocyte Antigen-C∗07 Expression in Patients with Endometriosis by Wenrong Zhao, Lei Lei, Rui Chen, Yanmin Zhang, Linlin Chang, Jingxin Cheng

“…Fifteen differentially methylated CpG sites were found among the patients and healthy women, and five CpG sites were mapped to the introns of the human leukocyte antigen-C (HLA-C) gene; these were highly polymorphic between different HLA-C alleles and were HLA-C∗07 specific. …”
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Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy by Laura Grunewald, Lena Andersch, Konstantin Helmsauer, Silke Schwiebert, Anika Klaus, Anton G. Henssen, Teresa Straka, Marco Lodrini, Sebastian G. Wicha, Steffen Fuchs, Falk Hertwig, Frank Westermann, Alice Vitali, Carlotta Caramel, Gabriele Büchel, Martin Eilers, Kathy Astrahantseff, Angelika Eggert, Uta E. Höpken, Johannes H. Schulte, Thomas Blankenstein, Kathleen Anders, Annette Künkele

“…Primary neuroblastomas possessing high MYCN levels expressed lower levels of both the L1CAM transcript and L1CAM tumor antigen. MLN8237 treatment restored L1CAM tumor expression and L1CAM-CAR T cell effector function. …”
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. by Athos Silva De Oliveira, Leroy Versteeg, Neima Briggs, Rakesh Adhikari, Maria Jose Villar, JeAnna R Redd, Peter Hotez, Maria Elena Bottazzi, Jeroen Pollet

“…<h4>Background</h4>The antigen Na-GST-1, expressed by the hookworm Necator americanus, plays crucial biochemical roles in parasite survival. …”
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