Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1α/FNDC5/BDNF Pathway by Yanqin Wu, Fusheng Sun, Yujin Guo, Yumao Zhang, Li Li, Ruili Dang, Pei Jiang

“…Of note, the PGC-1α inhibitor SR18292 remarkably reversed the beneficial effects of CUR on depressed rats, indicating an important role of PGC-1α in the antidepressant-like effects of CUR. Conclusion. Collectively, our data evaluating the neuroprotective action of CUR in the CUMS rats highlights the involvement of the PGC-1α/FNDC5/BDNF pathway in the antidepressant-like effects of CUR.…”
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New insights into anti-depression effects of bioactive phytochemicals by Ruohan Zhao, Jingwen Wang, Sookja Kim Chung, Baojun Xu

“…Therefore, this review aims to provide robust evidence for subsequent research into developing phytochemical resources as effective antidepressant agents.…”
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The Role of Neural Plasticity in Depression: From Hippocampus to Prefrontal Cortex by Wei Liu, Tongtong Ge, Yashu Leng, Zhenxiang Pan, Jie Fan, Wei Yang, Ranji Cui

“…The changes in neural plasticity induced by stress and other negative stimuli play a significant role in the onset and development of depression. Antidepressant treatments have also been found to exert their antidepressant effects through regulatory effects on neural plasticity. …”
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Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review by Perez-Rodriguez V, Aymerich C, Catalan A, Jauhar S, Salazar de Pablo G

“…In severe presentations, antidepressant-antipsychotic combination would be the treatment of choice. …”
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Low molecular mass chondroitin sulfate suppresses chronic unpredictable mild stress-induced depression-like behavior in mice by Si Xiao-Ming, Tian Yu-Hua, Zhang Sha-Sha, Gao Hua, Liu Kun, Jin Jing-Yu

“…The present study is aimed at testing the antidepressant--like effects and probable mechanisms of action of low molecular mass chondroitin sulfate (LMMCS) on depression induced by chronic unpredictable mild stress (CUMS) in mice. …”
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Transient Serotonin Toxicity Evoked by Combination of Electroconvulsive Therapy and Fluoxetine by René Klysner, Birgitte Bjerg Bendsen, Maja Soon Hansen

“…The serotonin syndrome has been described only in rare instances for electroconvulsive therapy combined with an antidepressant medication. We describe a case of serotonin toxicity induced by electroconvulsive therapy in combination with fluoxetine.…”
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Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression—An Animal Model Study by O. Malkesman, T. Asaf, L. Shbiro, A. Goldstein, R. Maayan, A. Weizman, N. Kinor, E. Okun, B. Sredni, G. Yadid, A. Weller

“…In the second phase, we examined the responsiveness of prepubertal WKY rats to different types of chronic antidepressant treatments: Fluoxetine, Desipramine, and dehydroepiandrosterone sulfate (DHEAS). …”
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Crack Cocaine-Induced Cardiac Conduction Abnormalities Are Reversed by Sodium Bicarbonate Infusion by Carlos Henrique Miranda, Antônio Pazin-Filho

“…During this intoxication, electrocardiographic abnormalities similar to those found in tricyclic antidepressant poisoning were observed, and they were reversed by intravenous sodium bicarbonate infusion.…”
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Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density? by Kim Chau, Stephanie A. Atkinson, Valerie H. Taylor

“…Both depression and antidepressant use have been identified as secondary causes of osteoporosis. …”
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Tea and depression by Klaus W. Lange, Yukiko Nakamura, Katharina M. Lange, Hui Zhao

“…A wide range of potentially antidepressive biological activities of tea components have been reported. …”
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Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature by Lampros Samartzis, Paraskevi Savvari, Sofoklis Kontogiannis, Stavros Dimopoulos

“…We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, the tricyclic antidepressant amitriptyline and the opioid analgesic fentanyl in a 68-year-old woman with advanced ischemic peripheral arterial disease and sepsis, under empirical antibiotic treatment. …”
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Muscle Relaxant and Sedative-Hypnotic Activities of Extract of Viola betonicifolia in Animal Models Supported by Its Isolated Compound, 4-Hydroxy Coumarin by Naveed Muhammad, Mohammad Saeed, Haroon Khan, Achyut Adhikari, Khalid Mohammed Khan

“…The crude methanolic extract of the whole plant of Viola betonicifolia (VBME) was investigated for anxiolytic, muscle relaxant, sleep induction, antidepressant, and sedative activities) to ascertain its scientific values. …”
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The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth by Erin Graves, David J. Hill, Susan Evers, Kristine Van Aarsen, Brie Yama, Su Yuan, M. Karen Campbell

“…High prepregnancy BM, height, antidepressant use, pregnancy weight-gain exceeding 40 pounds, and high blood sugar were associated with LGA birth, but not necessarily infant weight/length ratio. …”
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Comparative Pharmacokinetic Study of Three Major Bioactive Components in the Normal and Different Courses of Liver-Stagnation and Spleen-Deficiency Syndrome Depressive Rats after I... by Kaiwen Luo, Mengdie Wang, Xiangxiang Pan, Yadong Xing

“…This study provided important information for the clinical rational use of ZZHPD in antidepressant treatment.…”
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Radix Scutellariae Ameliorates Stress-Induced Depressive-Like Behaviors via Protecting Neurons through the TGFβ3-Smad2/3-Nedd9 Signaling Pathway by Fan Zhao, Chenyiyu Zhang, Dong Xiao, Weihua Zhang, Liping Zhou, Simeng Gu, Rong Qu

“…These results suggest that RS could exert antidepressant effects via protecting neurons. And the molecular mechanism might be related to the regulation of the TGFβ3-SMAD2/3-NEDD9 pathway.…”
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Pseudopheochromocytoma Associated with Domestic Assault by H. M. Le, G. Carbutti, D. Ilisei, E. Bouccin, X. Vandemergel

“…Treatment of pseudopheochromocytoma can be challenging due to normal blood pressure values in between the hypertensive peaks; it includes alpha- and beta-blockers for moderate crises and prevention and must be combined with psychopharmacologic agents such as anxiolytics or antidepressant drugs. Psychotherapy and dietetic treatment are also crucial in pseudopheochromocytoma management.…”
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Diffuse Hair Loss Induced by Sertraline Use by Yüksel Kıvrak, İbrahim Yağcı, Mehmet Fatih Üstündağ, Halil Özcan

“…Sertraline is a potent antidepressant which inhibits the serotonin reuptake from the presynaptic terminals selectively. …”
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Phytochemistry and Biological Activities of Poria by Jie Lu, Jing Tian, Li Zhou, Lijun Meng, Sitan Chen, Changyang Ma, Jinmei Wang, Zhenhua Liu, Changqin Li, Wenyi Kang

“…In this paper, we reviewed the literature, summarized the main compound types, and reviewed in detail their pharmacological effects in antitumor, immunomodulatory, effects on kidney, hepatoprotective activity, effects on blood sugar, antioxidant effects, anti-inflammatory effects, effects on the gut, antidepressant, and so on, and also categorized the compounds with the same or similar pharmacological effects to provide a reference for the in-depth study of the material basis of the pharmacological effect, quality standards, and pharmacological activity of Poria.…”
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Neurobiology of Major Depressive Disorder by Rosa Villanueva

“…Controversial issues, such as whether neurogenesis is the basis of the disease or whether it is a response induced by antidepressant treatments, are also discussed.…”
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Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression by Kasper Recourt, Joop Van Gerven, Joop Van Gerven, Nadieh Drenth, Jeroen van der Grond, Kantaro Nishigori, Nic J. Van Der Wee, Gabriël E. Jacobs, Gabriël E. Jacobs

“…IntroductionKetamine demonstrates robust and rapidly occurring antidepressant effects in patients with difficult-to-treat major depressive disorder. …”
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