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161
Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders
Published 2012-01-01“…In addition, adult hippocampal neurogenesis is highly correlated with the remission of the antidepressant effect. In this paper, we discuss three major psychiatric disorders, depression, schizophrenia, and drug addiction, in light of preclinical evidence used in establishing the neurobiological significance of adult neurogenesis. …”
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162
Aspects of improving metrological characteristics of a sensor based on palladium nanoparticles for methionine determination
Published 2025-01-01“…It enhances the synthesis of phospholipids, choline, and lecithin, as well as having an antidepressant effect due to its s-adenosylmethionine content. …”
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163
Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism
Published 2016-01-01“…In this test, a compound qualifies as a potential antidepressant if it prevents or delays the transition to this passive (energy conserving) behavioural style. …”
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164
Fluoxetine attenuates stress-induced depression-like behavior due to decrease in pro-inflammatory cytokines in male rats.
Published 2024“…We also investigated the effect of prior administration of the antidepressant drug fluoxetine on cytokines in animals exposed to both models of DLB. …”
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165
Behavioral phenotyping of Kaiso-deficient mice
Published 2015-12-01“…However, Kaiso gene deficiency produces a pronounced antidepressant-like effect in the forced swim test: Unlike WT mice, KO mice do not show any depressive-like freezing in this test. …”
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166
Effectiveness of Plant Adaptogens in Sports: Bibliometric Study and Prospects for Use
Published 2024-12-01“…Various publications have noted effects such as increased athletic performance, normalization of stress hormones after competitions, acceleration of healing of injuries, stimulation of muscle mass gain, an antidepressant effect, as well as acclimatization during intercontinental flights and preparation for competitions in unfavourable conditions. …”
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167
Phytochemistry and Biological Activities of Poria
Published 2021-01-01“…In this paper, we reviewed the literature, summarized the main compound types, and reviewed in detail their pharmacological effects in antitumor, immunomodulatory, effects on kidney, hepatoprotective activity, effects on blood sugar, antioxidant effects, anti-inflammatory effects, effects on the gut, antidepressant, and so on, and also categorized the compounds with the same or similar pharmacological effects to provide a reference for the in-depth study of the material basis of the pharmacological effect, quality standards, and pharmacological activity of Poria.…”
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168
Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review
Published 2025-01-01“…Rapid-acting neuroactive steroid-based antidepressants have been studied and approved in the United States (US) for the treatment of adult females with PPD. …”
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169
Improvement of Depression after Treatment of Dural Arteriovenous Fistula: A Case Report and a Review
Published 2012-01-01“…After this treatment, his depression as well as Gerstmann's syndrome was improved and the quantity of the antidepressants decreased. The patient returned to work without any antidepressant two years after the treatment. …”
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170
Role of BDNF-mTORC1 Signaling Pathway in Female Depression
Published 2021-01-01“…Moreover, recent studies suggest that the brain-derived neurotrophic factor- (BDNF-) mammalian target of rapamycin complex-1 (mTORC1) signaling pathway is a crucial target pathway for improving depression and mediates the rapid antidepressant-like effects of various antidepressants. …”
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171
Anxiety and depression in people with epilepsy during and one year after the COVID‐19 pandemic
Published 2025-02-01“…The only significant finding was that patients on anxiolytic or antidepressant medication had lower scores for anxiety and depression. …”
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172
Drug-Induced Myoclonus: A Systematic Review
Published 2025-01-01“…The subclasses of medications with level A evidence were intravenous anesthetics (etomidate), cephalosporins (ceftazidime, cefepime), fluoroquinolones (ciprofloxacin), selective serotonin reuptake inhibitors (citalopram, escitalopram, paroxetine, sertraline), tricyclic antidepressant (amitriptyline), glutamate antagonist (amantadine), atypical antipsychotics (clozapine, quetiapine), antiseizure medications (carbamazepine, oxcarbazepine, phenytoin, gabapentin, pregabalin, valproate), pure opioid agonist (fentanyl, morphine), bismuth salts, and mood stabilizers (lithium). …”
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173
Bifidobacterium breve BB05 alleviates depressive symptoms in mice via the AKT/mTOR pathway
Published 2025-01-01“…Mechanistic analysis revealed that BB05 exerts antidepressant effects by activating the AKT/mTOR signaling pathway in the prefrontal cortex, promoting neuroprotection, neurogenesis, and synaptic plasticity.DiscussionThese findings suggest that BB05, particularly at higher doses, effectively alleviates CUMS-induced depressive behaviors and improves physiological outcomes, supporting the use of probiotics as a potential treatment for depression by targeting the AKT/mTOR pathway.…”
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174
New Therapeutic Targets for Mood Disorders
Published 2010-01-01“…The paper reviews data on new compounds that have shown antimanic or antidepressant effects in subjects with mood disorders, or similar effects in preclinical animal models. …”
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175
Role of Ketamine in the Treatment of Psychiatric Disorders
Published 2021-06-01“…Current first-line treatment options are antidepressants of the selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) class. …”
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176
Predicting treatment response to ketamine in treatment-resistant depression using auditory mismatch negativity: Study protocol.
Published 2024-01-01“…Despite ketamine's promising results in treating depression, a significant number of patients do not respond to the treatment, and predicting who will benefit remains a challenge. Although its antidepressant effects are known to be linked to its action as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, the precise mechanisms that determine why some patients respond and others do not are still unclear.…”
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177
Acupuncture Alleviates CUMS-Induced Depression-Like Behaviors by Restoring Prefrontal Cortex Neuroplasticity
Published 2023-01-01“…Our study provides new insights into the antidepressant approach, and further studies are warranted to elucidate the mechanisms of acupuncture involved in depression treatment.…”
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178
Melatonin and its physiological and therapeutic effects: A review
Published 2024-01-01“…It has been proven that melatonin exerts neuroprotective and antidepressant like effects. Also, many researchers have found that melatonin plays an important role in various cardiovascular diseases. …”
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179
Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Transcranial Infrared Laser Stimulation
Published 2025-03-01“…This is the first study to investigate whether TILS would augment the antidepressant effects of internet-based cognitive behavioral therapy. …”
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180
Naringenin, a Food Bioactive Compound, Reduces Oncostatin M Through Blockade of PI3K/Akt/NF-κB Signal Pathway in Neutrophil-like Differentiated HL-60 Cells
Published 2025-01-01“…Although the food bioactive compound naringenin (NAR) exerts various useful effects, including antitussive, anti-inflammatory, hepatoprotective, renoprotective, antiarthritic, antitumor, antioxidant, neuroprotective, antidepressant, antinociceptive, antiatherosclerotic, and antidiabetic effects, the modulatory mechanism of NAR on OSM expression in neutrophils has not been specifically reported. …”
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