An Insight into Potential Pharmacotherapeutic Agents for Painful Diabetic Neuropathy by Zunaira Qureshi, Murtaza Najabat Ali, Minahil Khalid

“…Clinical studies have shown that anticonvulsant and antidepressant therapies have proven fruitful in management of pain associated with PDN. …”
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Maternal Characteristics of Women Exposed to Hypnotic Benzodiazepine Receptor Agonist during Pregnancy by Bjarke Askaa, Espen Jimenez-Solem, Henrik Enghusen Poulsen, Jon Traerup Andersen

“…Compared to unexposed women, exposed women were characterized by being older, with higher BMI, in their third or fourth parity, of lower income and education level, more frequently smokers, and more likely to be comedicated with antipsychotic, anxiolytic, or antidepressant drugs (P<0.0001). Conclusion. Women using HBRAs during their pregnancy differ from unexposed women in socioeconomic factors and were more likely to receive comedication. …”
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Adult-Onset Idiopathic Cervical Dystonia by Shameer Rafee, Mahmood Al-Hinai, Michael Hutchinson

“…Comprehensive modern management of patients with AOICD requires recognition of presence of mood disorders, and actively treating the endogenous mood disorder with antidepressant therapy. Botulinum toxin injections alone, no matter how expertly given, will not provide optimal therapy and improved health-related quality of life without an holistic approach to patient management. …”
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Cannabidiol Modulates Neuroinflammatory and Estrogen-Related Pathways in a Sex-Specific Manner in a Chronic Stress Model of Depression by Uri Bright, Irit Akirav

“…These findings highlight the sex-specific mechanisms of CBD’s antidepressant effect, with hippocampal neuroinflammatory and estrogenic pathways playing a key role in males.…”
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The Role of Neurokinin-1 Receptor in the Microenvironment of Inflammation and Cancer by Marisa Rosso, Miguel Muñoz, Michael Berger

“…Antagonists against the NK-1 receptor are safe clinical drugs that are known to have anti-inflammatory, analgesic, anxiolytic, antidepressant, and antiemetic effects. Recently, it has become apparent that SP can induce tumor cell proliferation, angiogenesis, and migration via the NK-1 receptor, and that the SP/NK-1 receptor complex is an integral part of the microenvironment of inflammation and cancer. …”
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Agomelatine Efficacy in the Night Eating Syndrome by Walter Milano, Michele De Rosa, Luca Milano, Anna Capasso

“…This paper describes a case report of an NES patient treated with agomelatine, an antidepressant analogue of melatonin, which acts by improving not only the mood but also by regulating sleep cycles and appetite. …”
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Depression as a Neuroendocrine Disorder: Emerging Neuropsychopharmacological Approaches beyond Monoamines by Mervin Chávez-Castillo, Victoria Núñez, Manuel Nava, Ángel Ortega, Milagros Rojas, Valmore Bermúdez, Joselyn Rojas-Quintero

“…Currently available antidepressant drugs are notoriously problematic, with suboptimal remission rates and troubling side-effect profiles. …”
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Possible Protective Effect of Sertraline against Cisplatin-Induced Ototoxicity: An Experimental Study by Murat Ozturk, Selcuk Ucar, Fatih Sarı, Selvet Erdogan, Murat Topdag, Mete Iseri

“…The aim of this study was to evaluate the otoprotective effect of sertraline, which is an antidepressant with neuroprotective effects, against cisplatin, in rats. …”
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Comparison of Different Machine Learning Methodologies for Predicting the Non‐Specific Treatment Response in Placebo Controlled Major Depressive Disorder Clinical Trials by Roberto Gomeni, Françoise Bressolle‐Gomeni

“…ABSTRACT Placebo effect represents a serious confounder for the assessment of treatment effect to the extent that it has become increasingly difficult to develop antidepressant medications appropriate for outperforming placebo. …”
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Phenotyping the males of mouse and rat strains with genetically defined behavioral disturbances in a model of sexual activation by M. A. Tikhonova, T. G. Amstislavskaya

“…The main gene for a high predisposition to catalepsy was shown to be associated with the expression of sexual motivation, but not with the hormonal component of sexual arousal (increase in plasma testosterone levels following exposure to a receptive female). ASC (Antidepressant Sensitive Catalepsy) mice, proposed as a model of depression, had a decreased manifestation of sexual motivation, while male GC (Genetic Catalepsy) strain rats had enhanced sexual motivation. …”
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Magnetic Seizure Therapy for Unipolar and Bipolar Depression: A Systematic Review by Eric Cretaz, André R. Brunoni, Beny Lafer

“…The studies found reported significant antidepressant effects, with remission rates ranging from 30% to 40%. …”
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Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders by Heechul Jun, Syed Mohammed Qasim Hussaini, Michael J. Rigby, Mi-Hyeon Jang

“…In addition, adult hippocampal neurogenesis is highly correlated with the remission of the antidepressant effect. In this paper, we discuss three major psychiatric disorders, depression, schizophrenia, and drug addiction, in light of preclinical evidence used in establishing the neurobiological significance of adult neurogenesis. …”
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Aspects of improving metrological characteristics of a sensor based on palladium nanoparticles for methionine determination by Eduard V. Gorchakov, Darya O. Perevezentseva, Elena A. Vaitulevich, Oksana V. Dubinina

“…It enhances the synthesis of phospholipids, choline, and lecithin, as well as having an antidepressant effect due to its s-adenosylmethionine content. …”
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Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism by E. R. de Kloet, M. L. Molendijk

“…In this test, a compound qualifies as a potential antidepressant if it prevents or delays the transition to this passive (energy conserving) behavioural style. …”
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Fluoxetine attenuates stress-induced depression-like behavior due to decrease in pro-inflammatory cytokines in male rats. by Nabirumbi, Ritah, Onohuean, Hope, Kato, Charles Drago, Alagbonsi, Abdullateef Isiaka, Adedeji1, Ahmed A.

“…We also investigated the effect of prior administration of the antidepressant drug fluoxetine on cytokines in animals exposed to both models of DLB. …”
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Behavioral phenotyping of Kaiso-deficient mice by V. S. Korostina, A. V. Kulikov

“…However, Kaiso gene deficiency produces a pronounced antidepressant-like effect in the forced swim test: Unlike WT mice, KO mice do not show any depressive-like freezing in this test. …”
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Effectiveness of Plant Adaptogens in Sports: Bibliometric Study and Prospects for Use by Igor V. Goncharenko, Viktoriia A. Pastukhova, Halyna V. Lukyantseva

“…Various publications have noted effects such as increased athletic performance, normalization of stress hormones after competitions, acceleration of healing of injuries, stimulation of muscle mass gain, an antidepressant effect, as well as acclimatization during intercontinental flights and preparation for competitions in unfavourable conditions. …”
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Phytochemistry and Biological Activities of Poria by Jie Lu, Jing Tian, Li Zhou, Lijun Meng, Sitan Chen, Changyang Ma, Jinmei Wang, Zhenhua Liu, Changqin Li, Wenyi Kang

“…In this paper, we reviewed the literature, summarized the main compound types, and reviewed in detail their pharmacological effects in antitumor, immunomodulatory, effects on kidney, hepatoprotective activity, effects on blood sugar, antioxidant effects, anti-inflammatory effects, effects on the gut, antidepressant, and so on, and also categorized the compounds with the same or similar pharmacological effects to provide a reference for the in-depth study of the material basis of the pharmacological effect, quality standards, and pharmacological activity of Poria.…”
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Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review by Giannopoulos A, Singh J, Deligiannidis KM

“…Rapid-acting neuroactive steroid-based antidepressants have been studied and approved in the United States (US) for the treatment of adult females with PPD. …”
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Improvement of Depression after Treatment of Dural Arteriovenous Fistula: A Case Report and a Review by Minoru Nakagawa, Kenji Sugiu, Koji Tokunaga, Chihoko Sakamoto, Kenjiro Fujiwara

“…After this treatment, his depression as well as Gerstmann's syndrome was improved and the quantity of the antidepressants decreased. The patient returned to work without any antidepressant two years after the treatment. …”
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