Bidirectional relationship between sleep and depression by Shinnosuke Yasugaki, Hibiki Okamura, Ami Kaneko, Yu Hayashi

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Assessment of Antidepressant Activity of Ethanolic Extract of Hibiscus rosa sinensis Linn.... by Sneha Ray, Swanand S Pathak

“…Hibiscus rosa sinensis (HRS) Linn (Malvaceae) blooms are a rich source of flavonoids, which have been shown to possess antidepressant properties. The current investigation seeks to evaluate the antidepressant effects of flavonoids in HRS Linn petals. …”
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Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness by Zhilu Zou, Yin Chen, Qinqin Shen, Xiaoyan Guo, Yuxuan Zhang, Gang Chen

“…We showed that a single low dose of Yueju demonstrated antidepressant effects in tests of tail suspension, forced swim, and novelty-suppressed feeding. …”
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Psychotropic drugs and bone by R.W. Gasser, H. Resch

Subjects: “…antidepressants…”
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Comparative antidepressant effects and safety of intravenous racemic ketamine, psilocybin and theta burst stimulation for major depressive disorder: A systematic review and network meta‐analyses of randomized controlled trials by Itsuki Terao, Wakako Kodama

“…In another subgroup analysis focusing on periods of 4 weeks or longer, IV ketamine and psilocybin showed significantly better antidepressant effects than placebo. The confidence in the evidence ranged from very low to moderate. …”
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Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis by Awad Al-Omari, Juthaporn Cowan, Lucy Turner, Curtis Cooper

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The risks of adverse events with mirtazapine for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis by Caroline Barkholt Kamp, Johanne Juul Petersen, Pascal Faltermeier, Sophie Juul, Christina Dam Bjerregaard Sillassen, Faiza Siddiqui, Rebecca Kjaer Andersen, Joanna Moncrieff, Mark Abie Horowitz, Michael Pascal Hengartner, Irving Kirsch, Christian Gluud, Janus Christian Jakobsen

Subjects: “…Antidepressants…”
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Insomnia: definition, pathophysiological models, diagnosis, and treatment by E. Sakalauskaitė-Juodeikienė, R. Masaitienė

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MORE ATTENTION TO QUALITY OF PHARMACOTHERAPY IN PSYCHIATRY by ERKKI ISOMETSÄ

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Unveiling the Mechanisms of a Remission in Major Depressive Disorder (MDD)-like Syndrome: The Role of Hippocampal Palmitoyltransferase Expression and Stress Susceptibility by Careen A. Schroeter, Anna Gorlova, Michael Sicker, Aleksei Umriukhin, Alisa Burova, Boris Shulgin, Sergey Morozov, Joao P. Costa-Nunes, Tatyana Strekalova

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Guidelines on the management of irritable bowel syndrome by Anna Pietrzak, Barbara Skrzydło-Radomańska, Agata Mulak, Michał Lipiński, Ewa Małecka-Panas, Jarosław Reguła, Grażyna Rydzewska

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Fractal cycles of sleep, a new aperiodic activity-based definition of sleep cycles by Yevgenia Rosenblum, Mahdad Jafarzadeh Esfahani, Nico Adelhöfer, Paul Zerr, Melanie Furrer, Reto Huber, Famke F Roest, Axel Steiger, Marcel Zeising, Csenge G Horváth, Bence Schneider, Róbert Bódizs, Martin Dresler

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Neuropathic Pain Management: Prescription Strategies in a Tertiary Care Setting by Chethan Kumar JK, Jason Fernandes Jokem, Chandralekha N, Padmaja Udaykumar

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Depression Following Thrombotic Cardiovascular Events in Elderly Medicare Beneficiaries: Risk of Morbidity and Mortality by Christopher M. Blanchette, Linda Simoni-Wastila, Fadia T. Shaya, Denise Orwig, Jason Noel, Bruce Stuart

“…Purpose. Depression and antidepressant use may independently increase the risk of acute myocardial infarction and mortality in adults. …”
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Effect of Vitamin B12 supplementation in late-life depression: A randomized controlled trial by Pooja Misal, Shrikant Srivastava, Akanksha Sonal, Vivek Agarwal, Wahid Ali

“…Background: Late-life depression (LLD) has a poor response to the first-line standard antidepressant medications. This study aims to determine the effect of Vitamin B12 supplementation as an augmentation to the antidepressant medications as the first-line therapy in LLD to accelerate and/or maximize the response and remission. …”
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Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression by Juan Du, Ruyun Liu, Lin Ma, Yue Liu, Wei Wei, Ning Liu, Qiuhua Cao, Jianqiang Yu

“…Abstract Histone deacetylase-5 (HDAC5) is implicated in the pathogenesis of depression and the mechanistic pathways underlying the effects of antidepressant medications. We previously identified a novel HDAC5 inhibitor, T2943, with antidepressant properties that promote histone 3 lysine-14 acetylation (H3K14ac) by inhibiting HDAC5 activity. …”
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Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1α/FNDC5/BDNF Pathway by Yanqin Wu, Fusheng Sun, Yujin Guo, Yumao Zhang, Li Li, Ruili Dang, Pei Jiang

“…Of note, the PGC-1α inhibitor SR18292 remarkably reversed the beneficial effects of CUR on depressed rats, indicating an important role of PGC-1α in the antidepressant-like effects of CUR. Conclusion. Collectively, our data evaluating the neuroprotective action of CUR in the CUMS rats highlights the involvement of the PGC-1α/FNDC5/BDNF pathway in the antidepressant-like effects of CUR.…”
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C-Reactive Protein As A Response Indicator In Drug-Naïve Patients With Major Depressive Disorder: A Hospital-Based Study by Ather Muneer, Nargis Munir, Nadia Shams, Mirza Inam, Usman Ghani, Neelam Ayub

“…Patients with first-episode MDD with no history of antidepressant exposure and other medical comorbidity were recruited for pharmacotherapy with escitalopram, a first-line antidepressant. …”
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Mirtazapine Treatment of a Severe Depressive Episode and Resolution of Elevated Inflammatory Markers by Shahzad M. Alikhan, Jessica A. Lee, Luiz Dratcu

“…This observation adds to the evidence that changes in inflammatory responses may be implicated in the mode of action of antidepressants. Further studies of antidepressant responses to mirtazapine and levels of inflammatory markers in depressed patients without medical comorbidity can help elucidate the role of the immune system in the pathophysiology of depression, and hence contribute to the development of novel antidepressant therapies.…”
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Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review by Perez-Rodriguez V, Aymerich C, Catalan A, Jauhar S, Salazar de Pablo G

“…In severe presentations, antidepressant-antipsychotic combination would be the treatment of choice. …”
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