New insights into anti-depression effects of bioactive phytochemicals by Ruohan Zhao, Jingwen Wang, Sookja Kim Chung, Baojun Xu

“…Therefore, this review aims to provide robust evidence for subsequent research into developing phytochemical resources as effective antidepressant agents.…”
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Overlapping of Serotonin Syndrome with Neuroleptic Malignant Syndrome due to Linezolid-Fluoxetine and Olanzapine-Metoclopramide Interactions: A Case Report of Two Serious Adverse D... by Faizan Mazhar, Shahzad Akram, Nafis Haider, Rafeeque Ahmed

“…Antipsychotic and antidepressant are often used in combination for the treatment of neuropsychiatric disorders. …”
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Exercise‐Activated mPFC Tri‐Synaptic Pathway Ameliorates Depression‐Like Behaviors in Mouse by Tian Lan, Ye Li, Xiao Chen, Wenjing Wang, Changmin Wang, Haiyan Lou, Shihong Chen, Shuyan Yu

“…In addition, it is found that exercise may exert antidepressant effects through regulating synaptic plasticity within this tri‐synaptic pathway. …”
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Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density? by Kim Chau, Stephanie A. Atkinson, Valerie H. Taylor

“…Both depression and antidepressant use have been identified as secondary causes of osteoporosis. …”
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Low molecular mass chondroitin sulfate suppresses chronic unpredictable mild stress-induced depression-like behavior in mice by Si Xiao-Ming, Tian Yu-Hua, Zhang Sha-Sha, Gao Hua, Liu Kun, Jin Jing-Yu

“…The present study is aimed at testing the antidepressant--like effects and probable mechanisms of action of low molecular mass chondroitin sulfate (LMMCS) on depression induced by chronic unpredictable mild stress (CUMS) in mice. …”
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The Role of Neural Plasticity in Depression: From Hippocampus to Prefrontal Cortex by Wei Liu, Tongtong Ge, Yashu Leng, Zhenxiang Pan, Jie Fan, Wei Yang, Ranji Cui

“…The changes in neural plasticity induced by stress and other negative stimuli play a significant role in the onset and development of depression. Antidepressant treatments have also been found to exert their antidepressant effects through regulatory effects on neural plasticity. …”
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Suicide Research and Adolescent Suicide Trends in New Zealand by Said Shahtahmasebi

“…In recent years, there have been a number of claims and counterclaims from suicide research using time series and longitudinal data; in particular, the linkage of increased antidepressant prescriptions to a decrease in suicide rates. …”
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Muscle Relaxant and Sedative-Hypnotic Activities of Extract of Viola betonicifolia in Animal Models Supported by Its Isolated Compound, 4-Hydroxy Coumarin by Naveed Muhammad, Mohammad Saeed, Haroon Khan, Achyut Adhikari, Khalid Mohammed Khan

“…The crude methanolic extract of the whole plant of Viola betonicifolia (VBME) was investigated for anxiolytic, muscle relaxant, sleep induction, antidepressant, and sedative activities) to ascertain its scientific values. …”
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Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes by Wenbo Xu, Xiaoxiao Yao, Fangyi Zhao, Haisheng Zhao, Ziqian Cheng, Wei Yang, Ranji Cui, Songbai Xu, Bingjin Li

“…Studies have shown that some antidepressants can treat depression by changing the plasticity of the hippocampus. …”
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Comparative Pharmacokinetic Study of Three Major Bioactive Components in the Normal and Different Courses of Liver-Stagnation and Spleen-Deficiency Syndrome Depressive Rats after I... by Kaiwen Luo, Mengdie Wang, Xiangxiang Pan, Yadong Xing

“…This study provided important information for the clinical rational use of ZZHPD in antidepressant treatment.…”
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Transient Serotonin Toxicity Evoked by Combination of Electroconvulsive Therapy and Fluoxetine by René Klysner, Birgitte Bjerg Bendsen, Maja Soon Hansen

“…The serotonin syndrome has been described only in rare instances for electroconvulsive therapy combined with an antidepressant medication. We describe a case of serotonin toxicity induced by electroconvulsive therapy in combination with fluoxetine.…”
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Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression—An Animal Model Study by O. Malkesman, T. Asaf, L. Shbiro, A. Goldstein, R. Maayan, A. Weizman, N. Kinor, E. Okun, B. Sredni, G. Yadid, A. Weller

“…In the second phase, we examined the responsiveness of prepubertal WKY rats to different types of chronic antidepressant treatments: Fluoxetine, Desipramine, and dehydroepiandrosterone sulfate (DHEAS). …”
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The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth by Erin Graves, David J. Hill, Susan Evers, Kristine Van Aarsen, Brie Yama, Su Yuan, M. Karen Campbell

“…High prepregnancy BM, height, antidepressant use, pregnancy weight-gain exceeding 40 pounds, and high blood sugar were associated with LGA birth, but not necessarily infant weight/length ratio. …”
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Radix Scutellariae Ameliorates Stress-Induced Depressive-Like Behaviors via Protecting Neurons through the TGFβ3-Smad2/3-Nedd9 Signaling Pathway by Fan Zhao, Chenyiyu Zhang, Dong Xiao, Weihua Zhang, Liping Zhou, Simeng Gu, Rong Qu

“…These results suggest that RS could exert antidepressant effects via protecting neurons. And the molecular mechanism might be related to the regulation of the TGFβ3-SMAD2/3-NEDD9 pathway.…”
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Neurobiology of Major Depressive Disorder by Rosa Villanueva

“…Controversial issues, such as whether neurogenesis is the basis of the disease or whether it is a response induced by antidepressant treatments, are also discussed.…”
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Crack Cocaine-Induced Cardiac Conduction Abnormalities Are Reversed by Sodium Bicarbonate Infusion by Carlos Henrique Miranda, Antônio Pazin-Filho

“…During this intoxication, electrocardiographic abnormalities similar to those found in tricyclic antidepressant poisoning were observed, and they were reversed by intravenous sodium bicarbonate infusion.…”
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Do individuals with inflammatory arthritis receive minimally adequate treatment for incident depression and anxiety: A population-based study by Alyssa Howren, Eric C. Sayre, J. Antonio Avina-Zubieta, Joseph H. Puyat, Deborah Da Costa, Hui Xie, Eileen Davidson, Amit Gupta, Mary A. De Vera

“…We defined minimally adequate pharmacotherapy as antidepressant prescriptions filled with ≥ 84 days’ supply and adequate psychological treatment as ≥ 4 counselling/psychotherapy services. …”
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Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression by Kasper Recourt, Joop Van Gerven, Joop Van Gerven, Nadieh Drenth, Jeroen van der Grond, Kantaro Nishigori, Nic J. Van Der Wee, Gabriël E. Jacobs, Gabriël E. Jacobs

“…IntroductionKetamine demonstrates robust and rapidly occurring antidepressant effects in patients with difficult-to-treat major depressive disorder. …”
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Use of Methadone for Neuropathic Pain by Dwight Moulin

“…Anticonvulsant and antidepressant treatments provide effective analgesia in up to 50% of patients with chronic neuropathic pain (2) and there is a growing body of high-quality evidence that controlled-release opioid analgesics provide substantial pain relief in a further subset of patients (3-6). …”
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Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature by Lampros Samartzis, Paraskevi Savvari, Sofoklis Kontogiannis, Stavros Dimopoulos

“…We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, the tricyclic antidepressant amitriptyline and the opioid analgesic fentanyl in a 68-year-old woman with advanced ischemic peripheral arterial disease and sepsis, under empirical antibiotic treatment. …”
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