Showing 281 - 300 results of 303 for search '"antidepressant"', query time: 0.07s Refine Results
  1. 281

    Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary car... by Alice Malpass, Glyn Lewis, Jude Robinson, Christopher Dowrick, Naila Khan, Louise Fusco

    Published 2017-05-01
    “…Our objectives were to ascertain patients’ views on the source and meaning of mismatches and assess their clinical significance.Design Qualitative study nested within a cohort, in a programme investigating the indications for prescribing antidepressants that will lead to a clinical benefit.Setting Primary care practices in north-west England.Participants We invited 32 adults with a recent diagnosis of depression and evidence of mismatch between GRC and PHQ-9 Scores to participate. …”
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  2. 282

    Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. by Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins

    Published 2025-01-01
    “…In this pilot study, our goal was to classify 19 neuroactive compounds into their functional categories: antipsychotics, anxiolytics, and antidepressants. Drug classification was performed with the same computational methods, using either physicochemical descriptors or planarian behavioral profiling. …”
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  3. 283

    Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression by Lili Hu, Na Wu, Jue Wang, Donghui Cai

    Published 2025-01-01
    “…Our research reveals novel mechanisms underlying the anti-MDD effects of PHE through network pharmacology and experiments, which provides a new direction for the development of antidepressants.…”
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  4. 284

    Neuropathic pain among patients with primary knee osteoarthritis: Results of a cross-sectional study from a tertiary care center in Southern India by R Vignesh Narayan, Molly Mary Thabah, Murali Poduval

    Published 2017-01-01
    “…Centrally acting drugs such as tricyclic antidepressants or duloxetine can be used to improve the quality of life and physical function of knee OA patients with neuropathic pain.…”
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  5. 285

    Enhancement of BDNF Concentration and Restoration of the Hypothalamic-Pituitary-Adrenal Axis Accompany Reduced Depressive-Like Behaviour in Stressed Ovariectomised Rats Treated wit... by Badriya Al-Rahbi, Rahimah Zakaria, Zahiruddin Othman, Asma’ Hassan, Asma Hayati Ahmad

    Published 2014-01-01
    “…In conclusion, both Tualang honey and E2 mediate antidepressive-like effects in stressed OVX rats, possibly acting via restoration of hypothalamic-pituitary-adrenal axis and enhancement of the BDNF concentration.…”
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  6. 286

    Drugs and Constipation in Elderly in Nursing Homes: What Is the Relation? by Gunvor S. Fosnes, Stian Lydersen, Per G. Farup

    Published 2012-01-01
    “…Reduced activity of daily living (OR = 0.71, 95% CI : 0.60–0.84, P<0.001), other antidepressants (N06AX) (OR 3.08, 95% CI : 1.09–8.68, P=0.03), and benzodiazepine derivatives (N05BA) (OR = 2.80, 95% CI : 1.12–7.04, P=0.03) were significantly associated with constipation; drugs with markedly anticholinergic effect (OR = 3.7, 95% CI : 0.78–17.53, P=0.10), natural opium alkaloid (N02AA) (OR = 5.01, 95% CI : 0.95–25.94, P=0.06), and propionic acid derivatives (M01AE) (OR = 7.00, 95% CI : 0.75–65.08, P=0.09) showed a trend. …”
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  7. 287

    Physicians’ and patients’ perceived risks of chronic pain medication and co-medications in Quebec, Canada: a cross-sectional study by Gwenaëlle De Clifford-Faugère, Anaïs Lacasse, Hermine Lore Nguena Nguefack, Marimée Godbout-Parent, Aline Boulanger, Nancy Julien

    Published 2025-01-01
    “…For eight subclasses, the difference in the mean perceived risk score was > 2 points and statistically significant (p < 0.05): non-specific oral NSAIDs, acetaminophen in combination with an opioid, short-acting opioids, long-acting opioids, tricyclic antidepressants, antipsychotics, benzodiazepines, and medical cannabis. …”
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  8. 288

    Trazodone effectiveness in depression: impacts of trazodone extended release vs SSRIs on the health status and quality of life of patients with major depressive disorder by Marcin Siwek, Adrian Andrzej Chrobak, Anna Julia Krupa, Aleksandra Gorostowicz, Andrzej Juryk, Dominika Dudek

    Published 2025-01-01
    “…Studies have confirmed that antidepressants generally improve the functional outcomes in MDD, but very few works have compared the efficacies of specific drugs. …”
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  9. 289
  10. 290

    Reduction of depressive symptoms among patients with inflammatory bowel disease treated with biological therapy: a quantitative comparative incision study by J. Zinkevičiūtė, S. Ambrasas, A. Kiziela, R. Strumila, S. Brašiškienė, E. Dlugauskas

    Published 2019-06-01
    “…Patients diagnosed with active ulcerative colitis or Crohn’s disease and not using antidepressants were included in the study. Participants were divided into an experimental group (receiving tumor necrosis factor-alpha inhibitors) and control group (receiving treatment with other drugs). …”
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  11. 291

    Central nervous system (CNS) medications and polypharmacy in later life: cross-sectional analysis of the English Longitudinal Study of Ageing (ELSA) by Natasha Slater, Simon White, Martin Frisher

    Published 2020-09-01
    “…The most common CNS drug classes in polypharmacy regimens were non-opioid analgesics, opioid analgesics, tricyclic and related antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) (34.6%, 13.2%, 10.9% and 10.4%, respectively). …”
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  12. 292

    INTENSITY OF OXIDATIVE STRESS DEVELOPMENT IN RAT MAJOR CEREBRAL HEMISPHERES UNDER COMBINED CONDITIONS OF SYSTEMIC INFLAMMATORY RESPONSE, CHANGES IN THE NORMAL LIGHT-DARK CYCLE, AN... by O.A. Volkova, V.O. Kostenko

    Published 2024-07-01
    “…At present, the relevance of examining changes to the normal light-dark cycle is increasing, and the connection between the development of the systemic inflammatory response (SIR) and circadian rhythm disorders has been confirmed. The effects of antidepressants on the human body are also actively studied. …”
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  13. 293

    Focus on Depression in Parkinson’s Disease: A Delphi Consensus of Experts in Psychiatry, Neurology, and Geriatrics by Luis Agüera-Ortiz, Rocío García-Ramos, Francisco J. Grandas Pérez, Jorge López-Álvarez, José Manuel Montes Rodríguez, F. Javier Olazarán Rodríguez, Javier Olivera Pueyo, Carmelo Pelegrín Valero, Jesús Porta-Etessam

    Published 2021-01-01
    “…Efficacious and well-tolerated pharmacological options for Parkinson’s comorbid depression were selective serotonin reuptake inhibitors (especially sertraline), dual-action serotonin and norepinephrine reuptake inhibitors (venlafaxine, desvenlafaxine, and duloxetine), multimodal (vortioxetine, bupropion, mirtazapine, and tianeptine), and anti-Parkinsonian dopamine agonists (pramipexole, ropinirole, and rotigotine). Tricyclic antidepressants and combining type B monoamine oxidase inhibitors with serotonergic drugs have serious side effects in these patients and therefore should not be prescribed. …”
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  14. 294

    Suicidality and Illness Course Worsening in a Male Patient with Bipolar Disorder during Tamoxifen Treatment for ER+/HER2+ Breast Cancer by Claudia Carmassi, Francesco Pardini, Valerio Dell’Oste, Annalisa Cordone, Virginia Pedrinelli, Marly Simoncini, Liliana Dell’Osso

    Published 2021-01-01
    “…The clinical picture showed poor response to treatment trials based on various associations of mood-stabilising, antidepressants, and antipsychotic drugs. During the second hospitalization, after a multidisciplinary evaluation, the oncologists agreed on Tamoxifen discontinuation upon the severity of the psychiatric condition. …”
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  15. 295

    Patterns of self-harm presentations at a Tertiary Urban Hospital in Kenya: A retrospective 5-year study (2018-2022). by Willie Njoroge, Catherine Gitau, Everline Onchari, Linnet Ongeri, Linda Khakali, Murad Khan, Zul Merali, Lukoye Atwoli, Jasmit Shah

    Published 2025-01-01
    “…Analgesics were the most frequently reported type of overdose, followed by tricyclic antidepressants. In context of self-injury, cutting emerged as the predominant form of self-harm. …”
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  16. 296

    Impact of the COVID-19 pandemic on psychotropic prescribing: a systematic review by Nikolaos Mastellos, Marie line El Asmar, Kanika I Dharmayat, Antonio J Vallejo-Vaz, Ryan Irwin, Swettha Mahesarajah

    Published 2024-09-01
    “…No particular trends were observed for the prescription rates of hypnotics, antidepressants or antipsychotics.Conclusions Findings support mixed trends in the prescription of psychotropic medications in a range of settings, hindering conclusive statements on COVID-19’s impact on prescribing. …”
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  17. 297
  18. 298

    Rural–urban and age differences in association between depression and suicidal attempt: a large retrospective clinical sample study in China by Yong Xia, Dandan Ge, Zhonghua Zhang

    Published 2025-01-01
    “…Notably, the predominant methods of suicide among individuals with depression were the utilisation of sleeping pills or antidepressants.Conclusion Our study found individuals with depression are at higher risk of SA, especially juveniles and urban individuals. …”
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  19. 299

    Dietary habits and weight change during the second wave of the COVID-19 pandemic among the Egyptian population by Samar Abd ElHafeez, Yasmine Amr Issa, Samar Tharwat, Ahmed Yahia Elmowafy, Karem Mohamed Salem, Noha Gaber Amin, Mohammed Kamal Nassar, Ramy Ghazy Mohamed

    Published 2025-01-01
    “…Weight loss was predicted by following COVID-19 pandemic reports daily [adjusted odds ratio (AOR) = 0.50 (95% CI, 0.27–0.93), p = 0.03], monthly income change [AOR = 2.52 (95% CI, 1.51–4.22), p < 0.001], starting antidepressants [AOR = 3.57 (95% CI, 1.08–11.76), p = 0.03], and increase in social media use [AOR = 1.81 (95% CI, 1.05–3.13), p = 0.03]. …”
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  20. 300

    Effects of physical activity on depressive and anxiety symptoms of women in the menopausal transition and menopause: a comprehensive systematic review and meta-analysis of randomiz... by Hongyu Yue, Yijiao Yang, Fangfang Xie, Jiahe Cui, Yang Li, Mengran Si, Shanshan Li, Fei Yao

    Published 2025-01-01
    “…In addition to traditional treatment strategies such as hormone therapy, antidepressants, and psychotherapy, physical activity (PA) have been increasingly studied, but there is no consensus about their role in menopausal women with depression and anxiety. …”
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