Antibodies to watch in 2024 by Silvia Crescioli, Hélène Kaplon, Alicia Chenoweth, Lin Wang, Jyothsna Visweswaraiah, Janice M. Reichert

Subjects: “…Antibody therapeutics…”
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A Longitudinal Comparison of the Recovery Patterns of Optic Neuritis with MOG Antibody-Seropositive and AQP4 Antibody-Seropositive or -Seronegative for Both Antibodies by Lin Zhou, Xiao Tan, Ling Wang, Xiujuan Zhao, Wei Qiu, Hui Yang

“…In this study, the aim is to compare the recovery pattern among patients with acute myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis (MOG-Ab + ON) attacks and aquaporin-4 antibody-seropositive ON (AQP4-Ab + ON) or -seronegative ON. …”
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Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli by Jacquelyn Blake-Hedges, Dan Groff, Wilson Foo, Jeffrey Hanson, Elenor Castillo, Miao Wen, Diana Cheung, Mary Rose Masikat, Jian Lu, Young Park, Nina Abi Carlos, Hans Usman, Kevin Fong, Abigail Yu, Sihong Zhou, Joyce Kwong, Cuong Tran, Xiaofan Li, Dawei Yuan, Trevor Hallam, Gang Yin

Subjects: “…Antibody–drug conjugate…”
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Can antibodies be “vegan”? A guide through the maze of today’s antibody generation methods by Stefan Dübel

Subjects: “…Monoclonal antibodies…”
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Comparison of IgA Endomysium Antibody and IgA Tissue Transglutaminase Antibody in Celiac Disease by Helen R Gillett, Hugh J Freeman

“…The antigen for immunoglobulin (Ig)Aendomysium antibody (EmA), a sensitive and specific serological marker for celiac disease, has recently been described as tissue transglutaminase (tTG). …”
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Heavy chain-only antibodies with a stabilized human VH in transgenic chickens for therapeutic antibody discovery by Christine N. Vuong, Kevin M. Reynolds, Gerry S. Rivera, Baisen Zeng, Zahra Karimpourkalou, Manith Norng, Yulei Zhang, Robayet Chowdhury, Darlene Pedersen, Melissa Pantoja, Ellen Collarini, Swetha Garimalla, Shelley Izquierdo, Eric G. Vajda, Brett Antonio, Devendra B. Srivastava, Marie-Cecile van de Lavoir, Yasmina Abdiche, William Harriman, Philip A. Leighton

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Developability considerations for bispecific and multispecific antibodies by Alaa Amash, Gesa Volkers, Patrick Farber, Daniel Griffin, K. Shawn Davison, Allison Goodman, Raffi Tonikian, Aaron Yamniuk, Bryan Barnhart, Tim Jacobs

Subjects: “…Antibody…”
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Presence of Autoimmune Antibody in Chikungunya Infection by Wirach Maek-a-nantawat, Udomsak Silachamroon

“…During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. …”
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Cost and supply considerations for antibody therapeutics by Chun Chen, Zoe Garcia, David Chen, Hong Liu, Piper Trelstad

Subjects: “…Antibody…”
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Seropositivity of Dengue Antibodies during Pregnancy by Nor Azlin Mohamed Ismail, Wan Elly Rushima Wan Abd Rahim, Sharifah Azura Salleh, Hui-Min Neoh, Rahman Jamal, Muhammad Abdul Jamil

“…Maternal with paired cord blood samples were tested for dengue antibodies (IgG and IgM) using an enzyme-linked immunosorbent assay (ELISA). …”
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Editorial: Antiviral monoclonal antibody therapies by Catalina Florez, Catalina Florez, Denise Haslwanter, Rohit K. Jangra, Rohit K. Jangra, Rohit K. Jangra

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Editorial: The immune response to therapeutic antibodies by Michael G. Tovey, Arno J. Kromminga, Daniel T. Mytych

Subjects: “…therapeutic antibodies…”
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Biparatopic antibodies: therapeutic applications and prospects by David L. Niquille, Kyle M. Fitzgerald, Nimish Gera

Subjects: “…Antibody engineering…”
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Role of Monoclonal Antibodies in the Treatment of Asthma by Paul M O’Byrne

“…New treatment approaches developed to manage some of the phenotypes of severe refractory asthma have included humanized monoclonal antibodies (hMabs).…”
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New Antibody Conjugates in Cancer Therapy by Serengulam V. Govindan, David M. Goldenberg

“…Targeting of radiation, drugs, and protein toxins to cancers selectively with monoclonal antibodies (MAbs) has been a topic of considerable interest and an area of continued development. …”
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A pivotal decade for bispecific antibodies? by Marlena Surowka, Christian Klein

“…Bispecific antibodies (bsAbs) are a class of antibodies that can mediate novel mechanisms of action compared to monospecific monoclonal antibodies (mAbs). …”
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Unveiling inverted D genes and D-D fusions in human antibody repertoires unlocks novel antibody diversity by Ponraj Prabakaran, Abhinav Gupta, Sambasiva P. Rao, Deepak Rajpal, Maria Wendt, Yu Qiu, Partha S. Chowdhury

“…We identified 25 unique inverted D genes (InvDs) in both naive and memory B cells from antibody repertoires of 13 healthy donors. These InvDs utilize all three reading frames during translation, producing distinct amino acid profiles enriched in histidine, proline, and lysine in CDR-H3s of antibodies with potential functional diversity. …”
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Electrostatic properties of human germlines and biodistribution of small biologics by Leticia Maria De Souza Cordeiro, Kelley Christine Atkinson, Argin Aivazian, Patrick Frank Joyce, Fang Jia, Alessandro Mascioni

Subjects: “…Antibody…”
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scFv Antibody: Principles and Clinical Application by Zuhaida Asra Ahmad, Swee Keong Yeap, Abdul Manaf Ali, Wan Yong Ho, Noorjahan Banu Mohamed Alitheen, Muhajir Hamid

“…Basically, scFv antibodies produced from phage display can be genetically fused to the marker proteins, such as fluorescent proteins or alkaline phosphatase. …”
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Lack of Antilipoprotein Lipase Antibodies in Takayasu's Arteritis by Jozélio Freire de Carvalho, Rosa Maria Rodrigues Pereira, Vilma Santos Trindade Viana, Eloísa Bonfá, Yehuda Shoenfeld

“…Antilipoprotein lipase (anti-LPL) antibodies were described in rheumatic diseases. In systemic lupus erythematosus they were highly associated with inflammatory markers and dyslipidemia, and may ultimately contribute to vascular damage. …”
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