Comprehensive characterization of higher order structure changes in methionine oxidized monoclonal antibodies via NMR chemometric analysis and biophysical approaches by Mingyue Li, Victor A. Beaumont, Shahajahan Akbar, Hannah Duncan, Arch Creasy, Wenge Wang, Kelly Sackett, Lisa Marzilli, Jason C. Rouse, Hai-Young Kim

“…The higher order structure (HOS) of monoclonal antibodies (mAbs) is an important quality attribute with strong contribution to clinically relevant biological functions and drug safety. …”
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Clinicopathological characteristics and outcomes of PLA2R related idiopathic membranous nephropathy in patients with seronegative PLA2R antibodies by Xue Li, Yang Shen, Yanchun Li, Lijie Ma, Qianmei Sun

“…We categorized patients into two groups based on the presence or absence of serum PLA2R antibody. Data on clinical features, pathological features, and outcomes were collected. …”
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Hyperbaric oxygen facilitates teniposide-induced cGAS-STING activation to enhance the antitumor efficacy of PD-1 antibody in HCC by Jian Lv, Kui-Sheng Yang, Chuan-Qi Xu

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A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies by Muhammed Emin Özcan, Meriç Adil Altınöz, Hasan Hüseyin Karadeli, Talip Asil, Abdulkadir Koçer

“…Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. …”
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Comparing Antibody Responses to Homologous vs. Heterologous COVID-19 Vaccination: A Cross-Sectional Analysis in an Urban Bangladeshi Population by Kazi Istiaque Sanin, Mansura Khanam, Azizur Rahman Sharaque, Mahbub Elahi, Bharati Rani Roy, Md. Khaledul Hasan, Goutam Kumar Dutta, Abir Dutta, Md. Nazmul Islam, Md. Safiqul Islam, Md. Nasir Ahmed Khan, Mustufa Mahmud, Nuzhat Nadia, Fablina Noushin, Anjan Kumar Roy, Protim Sarker, Fahmida Tofail

“…This study aimed to compare antibody responses between these booster approaches. …”
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Anti-SARS-CoV-2 Antibody Level among Renal Transplant Recipients: A Case Report from Nepal by Kamal Ranabhat, Bhuvan Saud, Saroj Adhikari, Suraj Bhattarai, Rojan Adhikari, Bhoj Raj Luitel, Mahesh Raj Sigdel

“…In this case report, we present the level of anti-SARS-CoV-2 antibody of three kidney transplant recipients after vaccination against COVID-19 virus. …”
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Development of a Luciferase Immunosorbent Assay for Detecting Crimean–Congo Hemorrhagic Fever Virus IgG Antibodies Based on Nucleoprotein by Qi Chen, Yuting Fang, Ning Zhang, Chengsong Wan

“…However, current methods for detecting anti-CCHFV antibodies are limited. This study aimed to develop a novel luciferase immunosorbent assay (LISA) for the detection of CCHFV-specific IgG antibodies. …”
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A Case of Systemic Lupus Erythematosus/Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Overlap Syndrome with Dissociated Pathological and Immunological Findings by Kazuhiko Kato, Tetsuya Kawamura, Risa Terashima, Yukiko Tsuchiya, Yasuhito Takahashi, Kenji Kasai, Takashi Yokoo

“…Systemic lupus erythematosus/antineutrophil cytoplasmic antibody-associated vasculitis overlap syndrome (SLE/AAV OS) describes a pathological condition that presents with overlapping features of two diseases. …”
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Significance of Semiquantitative Assessment of Preformed Donor-Specific Antibody Using Luminex Single Bead Assay in Living Related Liver Transplantation by Atsushi Yoshizawa, Hiroto Egawa, Kimiko Yurugi, Rie Hishida, Hiroaki Tsuji, Eiji Ashihara, Aya Miyagawa-Hayashino, Satoshi Teramukai, Taira Maekawa, Hironori Haga, Sinji Uemoto

“…To analyze the risks of preoperatively produced donor-specific antibody (DSA) in liver transplantation. Methods. DSA was assessed using direct complement-dependent cytotoxicity (CDC) and anti-human globulin- (AHG-) CDC tests, as well as the Luminex Single Antigen assay. …”
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Immunotherapy with IgY Antibodies toward Outer Membrane Protein F Protects Burned Mice against Pseudomonas aeruginosa Infection by Fatemeh Norouzi, Bahador Behrouz, Mahya Ranjbar, Seyed Latif Mousavi Gargari

“…The aim of this study was to evaluate the protective efficacy of egg yolk-specific antibody (IgY) raised against recombinant OprF (r-OprF) protein in a murine burn model of infection. …”
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Antibodies from a Patient with Type 1 Diabetes and Celiac Disease Bind to Macrophages that Express the Scavenger Receptor CD163 by Brigitte Sonier, Alexander Strom, Gen-Sheng Wang, Christopher Patrick, Jennifer A Crookshank, Majid Mojibian, Amanda J MacFarlane, Fraser W Scott

“…Blood monocytes and macrophage-like cells in human duodenum were also labelled with the enriched antibodies. Blocking studies revealed that binding to CD163+ macrophages was not due to cross-reactivity with anti-Glo-3A antibodies, but rather to non-Glo-3A antibodies co-purified during antibody enrichment. …”
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Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals by Najat Saeed Hussein, Izzat Abdulsatar Al-Rayahi, Salwa S. Muhsin, Redhwan Abdul Kareem Alameer

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Safety and Intranasal Retention of a Broad-Spectrum Anti-SARS-CoV-2 Monoclonal Antibody SA55 Nasal Spray in Healthy Volunteers: A Phase I Clinical Trial by Chaoying Hu, Yibo Zhou, Xing Meng, Jianhua Li, Jinxia Chen, Zhifang Ying, Xiaoliang Sunney Xie, Yaling Hu, Yunlong Cao, Ronghua Jin

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Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

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Assessment of infectious diseases in commercial frozen semen straws of water buffalo bulls. Preliminary results by Rosaura Pérez-Gil

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Rituximab (monoclonal anti-CD20 antibody) induced posterior reversible encephalopathy syndrome (PRES): A case report and literature review by Praveen K. Sharma, MD, Sanjaykanth Balachandar, MBBS, Michael Antony Vikram, MBBS, Pujitha Duvooru Sukumar, MD

“…Here, we present a 23-year-old female patient with systemic lupus erythematosus (SLE) and lupus nephritis who developed PRES following Rituximab (a monoclonal anti-CD-20 antibody) administration. The patient initially presented with severe headaches, visual disturbances, and an altered mental status. …”
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Long-term antibody responses to COVAXIN and COVISHIELD vaccines in rheumatoid arthritis patients and healthy control population – A cross-sectional study by Vijaya Prasanna Parimi, Anand Pyati, Madhavi Eerike

Subjects: “…antispike antibodies…”
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A simple, highly sensitive and specific serological test for the detection of antibodies to Varicella-zoster virus (<i>Varicellovirus humanalpha3</i>) by Firaya G. Nagieva, Elena P. Barkova, Olga S. Kharchenko, Alexander V. Sidorov, Galina I. Alatortseva, Bogdan S. Cherepovich, Yulia N. Tarakanova, Olga A. Trubacheva, Evgeny A. Pashkov, Artem A. Rtishchev, Oksana A. Svitich, Vitaly V. Zverev

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Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2 by Sophia Liu, Yuetian Yan, Cody M. Secor, Zachary R. Oberholtzer, Donna J. Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles

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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity by Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi

“…However, shedding or downregulation of NKG2D ligands (NKG2DL) can prevent NKG2D activation, resulting in escape of cancer cells from NKG2D-dependent immune surveillance.Methods To enable tumor-specific targeting of NKG2D-expressing effector cells independent of membrane-anchored NKG2DLs, we generated a homodimeric recombinant antibody which harbors an N-terminal single-chain fragment variable (scFv) antibody domain for binding to NKG2D, linked via a human IgG4 Fc region to a second C-terminal scFv antibody domain for recognition of the tumor-associated antigen ErbB2 (HER2). …”
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