Meningococcal Antigen Typing System Development and Application to the Evaluation of Effectiveness of Meningococcal B Vaccine and Possible Use for Other Purposes by Alexander Domnich, Roberto Gasparini, Daniela Amicizia, Giuseppe Boccadifuoco, Marzia Monica Giuliani, Donatella Panatto

“…Development of the 4-component meningococcal serogroup B vaccine (4CMenB) has required new assays for the reliable evaluation of the expression and cross-reactivity of those specific antigen variants that are predicted to be targeted by bactericidal antibodies elicited by the vaccine in different isolates. …”
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Lethal End of Spectrum of Clots-Thrombotic Storm by Muhammad Asim Rana, Ahmed F. Mady, Abdullah Ali Lashari, Rehab Eltreafi, Nicola Fischer-Orr, Kamal Naser

“…Usually, younger female patients are affected; in some patients, there is an association with an autoimmune disorder like lupus erythematosus, and they show evidence of antiphospholipid antibodies or other phenotypic expressions of anticoagulation disorders. …”
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Effects of Diet Based on IgG Elimination Combined with Probiotics on Migraine Plus Irritable Bowel Syndrome by Yangzhi Xie, Guijuan Zhou, Yan Xu, Bing He, Yilin Wang, Rundong Ma, Yunqian Chang, Duanqun He, Chenlin Xu, Zijian Xiao

“…A total of 60 patients diagnosed with migraine plus IBS were recruited for the study. IgG antibodies against 266 food varieties were detected by ELISA. …”
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Development of Acute Inflammatory Demyelinating Polyneuropathy 11 Days after Spinal Surgery: A Case Report and Literature Review by Eiichi Kakehi, Tadataka Kawakami, Yukiko Ishikawa, Takashi Matsuoka, Naoki Nakagawa, Tugutake Morishita, Shohei Taniguchi, Yukinobu Akamatsu, Shigehisa Sakurai, Akane Hirotani, Takafumi Nozaki, Keisuke Shoji, Seiji Adachi, Kazuhiko Kotani, Masami Matsumura

“…Although anti-GM1 and anti-GalNAc-GD1a antibodies were positive, the patient was clinically diagnosed with acute inflammatory demyelinating polyradiculoneuropathy (a subtype of GBS), not acute motor axonal neuropathy. …”
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Successful Management of Hemolytic Anemia Due to Rh-immunization, Diagnosed Antenatally by Sevinch Mahmudova, Gulnar Elizade, Nezrin Hesenli, Turab Janbakhishov, Sarkhan Elbayiyev

“…HDFN occurs when maternal alloimmunization leads to the production of immunoglobulin G (IgG) antibodies that cross the placenta and trigger fetal red blood cell hemolysis. …”
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Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

“…In a mouse xenograft model, M5A CAR-T cells displayed better antitumor efficacy without preconditioning.DiscussionOur findings suggest that scFvs derived from different antibodies have distinctive characteristics, and stable expression and appropriate affinity are critical for robust antitumor efficacy. …”
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Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle by A. D. Alekseev

“…It was established that injection of «Vidoral» in combination with vaccination against infectious rhinotracheitis, viral diarrhea, infection with respiratory syncytial virus and parainfluenza-3 virus induced generation of specific antibodies against the abovementioned infections.…”
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Tumor Biomarker In-Solution Quantification, Standard Production, and Multiplex Detection by Nicole C. Japp, Joshua J. Souchek, Aaron R. Sasson, Michael A. Hollingsworth, Surinder K. Batra, Wade M. Junker

“…This differs slightly from the R&D setting, where serum samples are often limiting; therefore, multiplexing antibodies to test multiple biomarkers in low serum volumes may be preferred. …”
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Vaccination Coverage and Associated Factors among Children Aged 12–23 Months in Debre Markos Town, Amhara Regional State, Ethiopia by Tenaw Gualu, Abebe Dilie

“…Vaccination is the administration of a vaccine or a biological substance intended to stimulate a recipient’s immune system to produce antibodies or undergo other changes that provide future protection against specific infectious diseases. …”
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Localisation of Abundant and Organ-Specific Genes Expressed in Rosa hybrida Leaves and Flower Buds by Direct In Situ RT-PCR by Agata Jedrzejuk, Heiko Mibus, Margrethe Serek

“…We used digoxygenin-11-dUTP, biotin-11-dUTP, and fluorescein-12-dUTP-labelled nucleotides and antidig-AP/ streptavidin-fluorescein-labelled antibodies. All of the used methods gave strong, specific signal and all of them may be used in localization of gene expression on tissue level in rose organs.…”
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Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion. by Francois Dao, Amadou Niangaly, Fanta Sogore, Mamadou Wague, Djeneba Dabitao, Siaka Goita, Aboubacrin S Hadara, Ousmaila Diakite, Mohamed Maiga, Fatoumata O Maiga, Chantal Cazevieille, Cecile Cassan, Arthur M Talman, Abdoulaye A Djimde, Alejandro Marin-Menendez, Laurent Dembélé

“…Regarding RBC invasion, quantified by an adapted flow cytometry based method, our study indicated that none of the seven antibodies tested, against receptors known for their role in P. falciparum invasion, had any impact on the ability of P. malariae to penetrate the host cells. …”
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Phenotype and Function of CD25-Expressing B Lymphocytes Isolated from Human Umbilical Cord Blood by Sylvie Amu, Mikael Brisslert

“…CD25-expressing B cells express a functional IL-2 receptor and high levels of CC-chemokine receptors and spontaneously produce antibodies of IgG and IgM subclass. Conclusions. CD25 expression is a common denominator of a specific immunomodulatory B-cell subset ready to proliferate upon IL-2 stimulation, possibly ready to migrate and home into the peripheral tissue for further differentiation/action.…”
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Urinary Podocyte Excretion Predicts Urinary Protein Selectivity and Renal Prognosis by Makoto Abe, Akiko Kaiga, Takehiro Ohira, Toshihiko Ishimitsu, Akihiro Tojo

“…Podocytes were identified in urinary sediments stained with fluorescent-labeled anti-podocalyxin antibodies in ten high power fields. The amounts of protein bands, separated by SDS-polyacrylamide gel electrophoresis, were calculated using an image software program and the correlation with urinary podocytes was analyzed. …”
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Overlap of Functional Gastrointestinal Disorders: Common Mechanisms of Pathogenesis as a Key to Rational Therapy by S. N. Mekhdiyev, O. A. Mekhdieva, O. M. Berko

“…As a pathogenetically justified pharmacotherapy of overlap syndrome, Kolofort, highly diluted antibodies to TNF-α, histamine and brain-specific protein S-100, is of interest.Conclusion. …”
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Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-γ) expression in colorectal carcinoma: Relation to the available cl... by Asmaa E. Bedeer, Nehal Abd El-Ghaffar Heabah

“…All cases were stained by CXCR4 and PPAR-γ antibodies to assess their immunohistochemical expression. …”
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Vedolizumab for inflammatory bowel diseasesI by Igor L. Khalif, M. V. Shapina

“…The vedolizumab is anti-α4β7-integrin humanized class IgG1 antibodies which suppresses migration of leukocytes in intestinal tissue, interfering thereby with development of pathologic inflammation. …”
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Picking interstitial lung disease out of the myositis haystack by Jennifer Hannah, Harsha Gunawardena

“…A number of myositis-CTD overlap associated antibodies and their clinical patterns have been described over the last few years. …”
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Platelet microparticles level in juvenile idiopathic arthritis: A pediatric population-based cross-sectional study in a tertiary care center by Naresh Kumar, K Anu Punnen, Sukesh Chandran Nair, Visalakshi Jayaseelan, T Sathish Kumar

“…Platelet microparticles were identified by MPs positive for both Annexin V and CD41 antibodies. Results: Out of 26 children with JIA, 12 had active disease group and 14 had inactive disease as assessed by Wallace criteria. …”
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Clinical Validation of an Office-Based 14C-UBT (Heliprobe) for H. pylori Diagnosis in Iranian Dyspeptic Patients by Fariborz Mansour-Ghanaei, Omid Sanaei, Farahnaz Joukar

“…Sera from all patients were investigated for the presence of H. pylori IgG antibodies. The 14C-UBT was performed on all subjects using Heliprobe kit, and results were analyzed against the following gold standard (GS): H. pylori infection considered positive when any two of three diagnostic methods (histopathology, RUT, serology) are positive. …”
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Seropositivity for Bovine Viral Diarrhea and Enzootic Bovine Leukemia viruses in Blanco Orejinegro cattle in Colombia and infection associated-factors by A. Saldarriaga-Saldarriaga, M. Londoño-Gil, L. G. González-Herrera, J. C. Rincón-Flórez, A. López-Herrera

“…A sample of 4 ml of blood was taken from each animal to extract plasma and make indirect Elisa tests to detect antibodies against both pathogens. General seropositivity of 27,1% was obtained for EBL, finding as factors associated with seropositivity the inadequate disposition of placental tissues after delivery of the cows and the non-performance of serological tests on new animals entering the herd. …”
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