Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells by Dana Emerson, Eve Merriman, Pia P. Yachi

“…We also assessed RA synovial fluid stimulated samples in the presence of various single cytokine neutralizing antibodies or SOC therapeutics, including glucocorticoids, TNF, IL-6 receptor and JAK inhibitors. …”
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Rimegepant for the treatment of migraine by Amnon A. Berger, Ariel Winnick, Austin H. Carroll, Alexandra Welschmeyer, Nathan Li, Marc Colon, Antonella Paladini, Giovanni F. Ramírez, Jamal Hasoon, Elyse M. Cornett, Jaehong Song, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…Novel medications, targeting CGRP, divide into CGRP antibodies and receptor antagonists (gepants). Rimegepant, a second-generation gepant, has shown efficacy in several clinical trials in treating acute migraine. …”
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Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-Infrared Fluorescent Anti–Epidermal Growth Factor Receptor Nanobody by Sabrina Oliveira, Guus A.M.S. van Dongen, Marijke Stigter-van Walsum, Rob C. Roovers, Jord C. Stam, Willem Mali, Paul J. van Diest, Paul M.P. van Bergen en Henegouwen

“…A number of studies have employed monoclonal antibodies as probes; however, their characteristic long half-life in the bloodstream has encouraged the development of smaller probes. …”
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Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer by Yao Mao, Jian'an Ren, Jieshou Li

“…Seventeen specimens of Crohn's disease dated between 2003/1/1 and 2005/1/1 were collected and underwent immunohistochemical analyses with cylcooxygenase 1, cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1 antibodies. Results. (1) The spatial distribution of the three leading enzymes in arachidonic acid pathway—cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1—followed sequential arrangement in Crohn's ulcer: neutrophils highly expressing 5-lipoxygenase were in the utmost surface which bordered the band of cyclooxygenase-2 expression that is located just beneath it, and in the lower layers and below the granulation region were eosinophils carrying 15-lipoxygeanse-1. (2) Cyclooxygenase-2 and 15-Lipoxygenase-1-positive cells formed two barrier-like structures that possibly inhibited neutrophil infiltration. …”
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Growth Hormone Therapy for Small for Gestational Age Short Stature Develops Type 2 Diabetes by Naohiro Nomura, Yuko Tanabe, Miki Minami, Junji Takaya, Kazunari Kaneko

“…Blood test results were negative for anti-glutamic acid decarboxylase and anti-islet antigen-2 antibodies. The patient discontinued GH therapy and started diet therapy and oral metformin (500 mg/day) administration. …”
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DEVELOPMENT AND IMPROVEMENT OF ASF SEROLOGICAL DIAGNOSTIC TECHNIQUES by D. V. Sharypova, O. V. Kapustina, I. Yu. Zhukov, N. N. Vlasova, A. S. Igolkin

“…The research is devoted to development of rapid test methods for rapid detection of antibodies to ASFV in blood sera of infected animals as well as to analysis of their use effectiveness. …”
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The Proviral Reservoirs of Human Immunodeficiency Virus (HIV) Infection by Andrey I. Murzin, Kirill A. Elfimov, Natalia M. Gashnikova

“…Uncovering the causes of this phenomenon will bring humanity closer to curing HIV infection, potential approaches to which include stem cell transplantation, clustered regularly interspaced short palindromic repeats (CRISPR)/cas9, “Shock and kill”, “Block and lock”, and the application of broad-spectrum neutralizing antibodies (bNAbs).…”
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Treatment of Functional Dyspepsia in Outpatients after COVID-19 Infection by M. S. Turchina, Yu. M. Morozov, T. I. Obolenskaya

“…All patients were divided in 2 groups by randomization: Group 1 received omeprazole at a dose of 80 mg/day, Group 2 received a combination of omeprazole and Kolofort® (a combined action drug product containing technologically processed antibodies to S100, TNF-alpha, and histamine) at a dose of 80 mg/day. …”
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Bidirectional Interaction of Thyroid-Kidney Organs in Disease States by Fateme Shamekhi Amiri

“…No association between antimicrosomal antibodies with estimated glomerular filtration rate was seen. …”
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Immune Responses to Tissue-Restricted Nonmajor Histocompatibility Complex Antigens in Allograft Rejection by Ankit Bharat, T. Mohanakumar

“…., cross-matching) to detect antibodies (Abs) against donor human leukocyte antigens, which has been shown to reduce Ab-mediated hyperacute rejection. …”
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Anti-SARS-CoV-2 Biotherapeutics and Chemotherapeutics: An Insight into Product Specifications and Marketing Dynamics by Vijay Kotra, Dinakar Mallem, Anil Kumar Kanuri, Mahesh Reddy Burra, Shaik Nyamathullah, Looi Shu Ying, Khairul Anwar Husain, Ravi Varala, Madhadevi Sudhakar, Khang Wen Goh, Toong Hai Sam, Long Chiau Ming

“…Hence, the prices of anti-viral and monoclonal antibodies in top COVID-19 affected countries is also presented here. …”
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ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics by Lennox Chitsike, John Krstenansky, Penelope J. Duerksen-Hughes

“…There is therefore an urgent need for additional therapies that complement vaccines and approved therapies such as antibodies in the fight to end or slow down the pandemic. …”
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Myasthenia gravis complicated by pure red cell aplasia with clonal large granular lymphocytosis in the absence of thymoma: a rare case report and literature review by Lijun Du, Yiping Liu, Qiaolin Zhou, Fang Xu

“…She was later diagnosed with myasthenia gravis (MG) based on positive acetylcholine receptor antibodies. Her muscle weakness was subsequently well-controlled with pyridostigmine bromide, azathioprine, and prednisone. …”
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Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning by Yue Hu, Yating Lin, Bo Peng, Chunyan Xiang, Wei Tang

“…The recent emergence of monoclonal antibodies, including mepolizumab, reslizumab, and benralizumab, offers therapeutic promise, yet their efficacy varies due to the heterogeneous nature of asthma. …”
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Tolerogenic Splenic IDO+ Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis by Jie Yang, Yiming Yang, Huahua Fan, Hejian Zou

“…The serological levels of inflammatory cytokines and anti-CII antibodies were low and TGF-β production was high in the DCiTreg-treated group. …”
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Acute Low-Dose Hydralazine-Induced Lupus Pneumonitis by Sarah K. Holman, Donique Parris, Sarah Meyers, Jason Ramirez

“…A clinical diagnosis of hydralazine-induced lupus (HIL) with pneumonitis was made. Antihistone antibodies were positive supporting a diagnosis of HIL. …”
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Prevalence of feline viral leukemia in Moscow and the Moscow Oblast with the analysis of hematological and biochemical blood parameters by A. P. Zenchenkova

“…Despite the statistical records that have been successfully kept in other countries for many years, there is little data on the prevalence of the infection in the Russian Federation, and the samples are represented by a small number of animals. 11,807 blood samples collected in Moscow and the Moscow Oblast were tested for FeLV antigen and antibodies against FeLV by polymerase chain reaction, enzyme immunoassay, and immunochromatographic assay. …”
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Canine parvovirus enteritis: epidemic situation analysis and perspectives by T. S. Galkina, A. К. Karaulov

“…Despite extensive vaccination, the main reason for the wide spread of the virus is either interference with maternal antibodies in vaccinated puppies or low level of immune protection in adult dogs.…”
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High Prevalence of Neutrophil Cytoplasmic Autoantibodies in Infants with Food Protein-Induced Proctitis/Proctocolitis: Autoimmunity Involvement? by Alena Sekerkova, Martin Fuchs, Eva Cecrdlova, Veronika Svachova, Ivana Kralova Lesna, Ilja Striz, Helena Tlaskalova-Hogenova

“…Results. Atypical-pANCA antibodies of IgG isotype were detected in the sera of 24 patients by the method of indirect immunofluorescence, and 5 patients showed also the positivity of IgA isotype. …”
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Complement activated granulocytes can cause autologous tissue destruction in man by E. Löhde, H. Raude, M. Lück, E. Kraas, W. Lierse

“…The respiratory burst could be completely abolished by decomplementation and preincubation with rabbit antihuman C5a antibodies. Observation of human omentum using electron microscopy showed intravascular aggregation of PMNs, with capillary thrombosis and diapedesis of the cells through endothelial junctions 90 s after exposure to ZAP. …”
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