Carbapenem-resistant Acinetobacter baumannii and Ventilator-associated Pneumonia; Epidemiology, Risk Factors, and Current Therapeutic Approaches by Malihe Kazemi Najafabadi, Rasool Soltani

“…Some approaches have been taken to deal with CRAB, such as combination therapy and the synergistic effect of certain antibiotics, but the best antibiotic regimen is still unknown. …”
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Impalement injury to the head with intact neurology following spontaneous Dane gun explosion: Two case reports and review of the literature by Yahaya A, Koko AM

“…Conclusion: The two cases of impalement head injury had remarkable recovery following prompt surgical removal, antibiotics and wound care. …”
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A rare case of culture-negative infective endocarditis following cataract surgery by Gayashani K. Jayasinghe, Logeswaran Dinusha, Udara S. Perera, Indrakumar Jegarajah

“…The patient was treated with empirical antibiotics, including vancomycin and ceftriaxone, which led to significant improvement. …”
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Understanding gender inequities in antimicrobial resistance: role of biology, behaviour and gender norms by Esmita Charani, Srishti Goel, Deepshikha Batheja

“…Key drivers of bacterial AMR include the misuse of antibiotics, inadequate water, sanitation and hygiene infrastructure and poor infection control practices. …”
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Colistin: The phoenix Arises by JM Conly, BL Johnston

“…The polymyxins were discovered in the 1940s and represent a group of closely related polypeptide antibiotics obtained from Bacillus polymyxa, which was originally isolated from soil (1,2). …”
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Acute Psychotic Episode Induced by Antimicrobial Treatment by Savera I. Arain, Majed Al Shakhori, Shabeer A. Thorakkattil, Omer Amin

“…Even though transient psychotic episodes have been reported previously with antibiotics, this case emphasizes the increased need for vigilance and reporting in patients receiving antimicrobials.…”
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Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review by Deepak Sharma, Ankur Patel, Priyanka Soni, Pradeep Sharma, Basudev Gupta

“…The sepsis screen was positive and blood culture and cerebrospinal fluid showed growth of Empedobacter brevis that was resistant to multiple antibiotics. The neonate was treated with appropriate antibiotics and was discharged successfully. …”
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Urosepsis Causing Gastric Ischemia: A Rare but Deadly Complication by Vijay Jarodiya, Chirag Kher, Sangeetha Nanthabalan, Gunjan Shah

“…The patient was treated conservatively with intermittent nasogastric tube suctioning, acid suppression therapy and broad-spectrum antibiotics. The patient improved clinically and repeat imaging and EGD showed resolution of the ischemia. …”
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The Mechanisms of Catalysis by Metallo 𝛽-Lactamases by Michael I. Page, Adriana Badarau

“…Class B 𝛽-lactamases or metallo-𝛽-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of 𝛽-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. …”
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Pancreas as an Occult Source of Recurrent Salmonella enteritidis Bacteremia in an Immunocompromised Patient by Don Bambino Geno Tai, Laxmi Upadhyay, Ruchika Jain, Robert Goldstein

“…She was treated with intravenous and oral antibiotics but still had recurrence of fevers and bacteremia. …”
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Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae. by Hedi Mammeri, Youssouf Sereme, Eya Toumi, Hélène Faury, David Skurnik

“…The increasing resistance of Gram-negative bacteria to last resort antibiotics, such as carbapenems, is particularly of concern as it is a significant cause of global health threat. …”
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Neglected Fournier’s Gangrene Caused by Acinetobacter baumannii: A Rare Case Report by Arif Emre, Mehmet Sertkaya, Sami Akbulut, Yakup Duman, Ilhami Taner Kale

“…Many treatment modalities including broad-spectrum antibiotics, aggressive debridement, negative pressure wound therapy, diversion colostomy, and partial-thickness skin grafts were applied to save the patient’s life.…”
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Primary Meningococcal Type C Arthritis: A Case Report and Literature Review by Maximiliano Barahona, Jaime Catalan, Yoshiro Sato, Jaime Hinzpeter

“…It has a very good response to antibiotics and arthroscopy procedure. Short-term follow-up and functional results are often good or excellent.…”
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Pouchitis unveiled: exploring clinical features, diagnosis, and cutting-edge treatments by Francesca Lusetti, Camilla Almeida Martins Helfenberger, Munique Kurtz de Mello, Natália Sousa Freitas Queiroz

“…Traditionally the mainstay treatment of acute pouchitis involves the use of antibiotics, but one-fifth of patients develop chronic pouchitis (CP), which may be dependent or resistant to antibiotics, posing significant challenges in the management of this condition. …”
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Trichophyton as a Rare Cause of Postoperative Wound Infection Resistant to Standard Empiric Antimicrobial Therapy by Sheema Gaffar, John K. Birknes, Kenji M. Cunnion

“…Multiple wound cultures consistently grew Trichophyton fungus, and his wound infection clinically improved rapidly after starting terbinafine and discontinuing antibiotics.…”
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Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development by Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussy, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga

“…Recent studies have shown that several natural product antibiotics targeting the unfoldase N-terminal domain can impair MtbClpC1 function resulting in cell death. …”
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Pola Kepekaan Bakteri Penyebab Pneumonia terhadap Antibiotika di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari sampai Desember 2011 by Jaka Kurniawan, Erly ., Rima Semiarty

“…The research method used was a descriptive and retrospective review of secondary data and antibiotic sensitivity test results of 432 patients types of germs. …”
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Determinants of Deescalation Failure in Critically Ill Patients with Sepsis: A Prospective Cohort Study by Nawal Salahuddin, Lama Amer, Mini Joseph, Alya El Hazmi, Hassan Hawa, Khalid Maghrabi

“…In this prospective study of patients with sepsis/septic shock, patients were categorized into 4 groups based on antibiotic administration: no change in antibiotics, deescalation, escalation (where antibiotics were changed to those with a broader spectrum of antimicrobial coverage), or mixed changes (where both escalation to a broader spectrum of coverage and discontinuation of antibiotics were carried out). …”
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Understanding biofilm--phage interactions in cystic fibrosis patients using mathematical frameworks by Emerenini Blessing O., Hartung Doris, Reyes Grimaldo Ricardo N. G., Canner Claire, Williams Maya, Agyingi Ephraim, Osgood Robert

“…Biofilm formation in a host can be extremely problematic if left untreated, especially since antibiotics can be ineffective in treating the bacteria. …”
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Clostridium difficile Peritonitis: An Emerging Infection in Peritoneal Dialysis Patients by Saira Chaughtai, Bhavika Gandhi, Zeeshan Chaughtai, Dana Tarina, Mohammad A. Hossain, Arif Asif

“…While the peritoneal fluid culture did not grow the organism (possibly because of prior empiric broad-spectrum antibiotics use), the positive PCR on stool analysis suggested C. difficile-related peritonitis, along with the rapid clinical improvement induced by C. difficile-directed therapy (metronidazole) and discontinuation of broad-spectrum antibiotics. …”
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