In-Hospital Macro-, Meso-, and Micro-Drivers and Interventions for Antibiotic Use and Resistance: A Rapid Evidence Synthesis of Data from Canada and Other OECD Countries by Rosa Stalteri Mastrangelo, Anisa Hajizadeh, Thomas Piggott, Mark Loeb, Michael Wilson, Luis Enrique Colunga Lozano, Yetiani Roldan, Hussein El-Khechen, Anna Miroshnychenko, Priya Thomas, Holger J. Schünemann, Robby Nieuwlaat

“…Hospitals continue to face challenges in reducing incorrect antibiotic use due to social and cultural factors at the level of the health system, the care facility, the provider, and the patient. …”
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Synthesizing evidence to guide the design and implementation of effective strategies for discontinuing postoperative antibiotic prophylaxis in surgical settings: an umbrella review post-WHO 2018 recommendations by George Msema Bwire, Renatus B. Magati, Hafidhi H. Ntissi, Tusaligwe Mbilinyi, Martine A. Manguzu, Goodluck G. Nyondo, Belinda J. Njiro, Lilian B. Nkinda, Castory G. Munishi, Obadia Nyongole, Pacifique Ndayishimiye, Mtebe V. Majigo

Subjects: “…Postoperative antibiotic prophylaxis…”
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Impact of video-based educational intervention to improve parents’ knowledge and awareness towards risk of antibiotic resistance in children: A pre-post interventional design by Syam Wahyu Romizatul Isnaeni, Kaaffah Silma, Fauziah Fauziah

“…Due to parental ignorance, carelessness, and inappropriate antibiotic treatment, antibiotic resistance in children is on the rise in Indonesia. …”
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New Option for Antibiotic Susceptibility Testing in Clinical Practice: Performance Evaluation of AutoMic-i600 Automatic System Based on Broth Microdilution Method by Lin C, Zhang H, Wu Q, Qiu X, Li Q, Wu G

Subjects: “…antibiotic susceptibility testing…”
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Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016–2021) by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

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Additive Effects of Glutathione in Improving Antibiotic Efficacy in HIV–<i>M.tb</i> Co-Infection in the Central Nervous System: A Systematic Review by Leena Nabipur, Michael Mouawad, Vishwanath Venketaraman

“…Glutathione (GSH) has the therapeutic potential to enhance treatment outcomes by improving antibiotic efficacy, reducing inflammation, and mitigating immune dysfunction. …”
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Clinical efficacy of antibiotic-loaded bone cement and negative pressure wound therapy in multidrug-resistant organisms diabetic foot ulcers: a retrospective analysis by Huihui Guo, Zhenqiang Xue, Siwei Mei, Tengfei Li, Haiyang Yu, Tao Ning, Yongbin Fu

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Exploring the potential mediating role of systemic antibiotics in the association between early-life lower respiratory tract infections and asthma at age 5 in the CHILD study by Maria V. Medeleanu, Maria V. Medeleanu, Myrtha E. Reyna, Myrtha E. Reyna, Darlene L. Y. Dai, Geoffrey L. Winsor, Fiona S. L. Brinkman, Rahul Verma, Ella Nugent, Nashita Riaz, Elinor Simons, Piushkumar J. Mandhane, Piushkumar J. Mandhane, Meghan B. Azad, Meghan B. Azad, Stuart E. Turvey, Stuart E. Turvey, Theo J. Moraes, Theo J. Moraes, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao, Padmaja Subbarao

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Assessment of Antibiotic Resistance and Efflux Pump Gene Expression in Neisseria Gonorrhoeae Isolates from South Africa by Quantitative Real-Time PCR and Regression Analysis by Nireshni Mitchev, Ravesh Singh, Veron Ramsuran, Arshad Ismail, Mushal Allam, Stanford Kwenda, Florah Mnyameni, Nigel Garrett, Khine Swe Swe-Han, Abraham J. Niehaus, Koleka P. Mlisana

“…The aim of this study was to correlate mRNA expression levels in Neisseria gonorrhoeae antibiotic target genes and efflux pump genes to antibiotic resistance in our population. …”
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Antibiotic Susceptibility Patterns and Virulence Profiles of Classical and Hypervirulent <i>Klebsiella pneumoniae</i> Strains Isolated from Clinical Samples in Khyber Pakhtunkhwa, Pakistan by Azra, Taj Ali Khan, Ihtisham Ul Haq, Woranich Hinthong, Susana Campino, Aisha Gohar, Noman Khan, Muhammad Kashif, Ihsan Ullah, Taane G. Clark

Subjects: “…antibiotic resistance…”
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Tristemma hirtum and Five Other Cameroonian Edible Plants with Weak or No Antibacterial Effects Modulate the Activities of Antibiotics against Gram-Negative Multidrug-Resistant Phenotypes by Gaëlle S. Nguenang, Armelle T. Mbaveng, Aimé G. Fankam, Hermione T. Manekeng, Paul Nayim, Brice E. N. Wamba, Victor Kuete

“…In order to contribute to the fight against infectious diseases, the in vitro antibacterial activity and the antibiotic-potentiating effects of Tristemma hirtum and five other Cameroonian edible plants have been evaluated against Gram-negative multidrug-resistant (MDR) phenotypes. …”
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Impact of Antimicrobial Stewardship and Infection Prevention and Control Programmes on Antibiotic Usage and A. baumannii resistance: A 2016&ndash;2023 Multicentre Prospective Study by Liu L, Liu B, Li L, Li Y, Zhou X, Li Q

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A Novel BiOBr/CAU‐17 Composite with Enhanced Photo‐Catalytic Performance for Dye Degradation and Removal of Tetracycline Antibiotic Under Visible Light by Mansoor Akhtar, Shifa Ullah Khan, Ghulam Mustafa, Muhammad Ahmad, Tansir Ahamad

“…This study offers a new understanding for the design of green synthesis schemes for photo‐catalytic dye degradation and removal of certain antibiotics from the aquatic environment.…”
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Bacterial Profile and Antibiotic Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Antenatal Care at a Tertiary Care Hospital in Southern Ethiopia by Ashenafi Tula, Abraham Mikru, Tsegaye Alemayehu, Beyene Dobo

“…Screening for the presence of urinary tract infection during pregnancy will improve the quality of antenatal care further reducing complication. The above antibiotics can be prescribed based on the side effect to pregnant women in case empirical treatment is mandatory in the study area.…”
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Impact of Topically Administered Steroids, Antibiotics, and Sodium Hyaluronate on Bleb-Related Infection Onset: The Japan Glaucoma Society Survey of Bleb-Related Infection Report 4 by Hideto Sagara, Tetsuya Yamamoto, Kimihiro Imaizumi, Tetsuju Sekiryu

“…The median duration from surgery to infection for the antibiotic-administered eyes was 6.4 years versus 3.9 years for eyes without antibiotic administration (P=0.025). …”
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Whole-Genome Sequence of Streptomyces pluripotens strain MUM 16J, a Potential Resource of Glycopeptide Antibiotic and Biocontrol Agent against Biofilm-forming Bacteria by Priyia Pusparajah, Jodi Woan-Fei Law, Kok-Gan Chan, Bey-Hing Goh, Kar-Wai Hong, Learn-Han Lee, Loh Teng-Hern Tan

“…Here we report the draft genome of this strain to highlight its potential in producing glycopeptide antibiotic as well as catechol, a biocontrol agent of biofilm-producing bacteria. …”
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Antibacterial efficacy and antibiotic sensitivity augmentation potential of selected traditional medicinal plant extracts against Vibrio cholerae O1 E1 Tor Ogawa by Pruthviraj Chavan, Kamakshi Naik, Soumika Ghosal, Rajitha Charla, Rajalakshmi Patil, Jyoti N. Guruputranavar, Vishal S. Patil, Darasaguppe R. Harish, Subarna Roy

Subjects: “…Antibiotic potentiation…”
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Sulbactam–Durlobactam: A Novel Antibiotic Combination for the Treatment of Acinetobacter baumannii–Calcoaceticus Complex (ABC) Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia by Wissam K. Kabbara, Elina Sadek, Hanine Mansour

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Examining the effect of direct-from-blood bacterial testing on antibiotic administration and clinical outcomes: a protocol and statistical analysis plan for a pragmatic randomised trial by Li Wang, Wesley H Self, Todd W Rice, Matthew W Semler, Karen F Miller, Cheryl L Gatto, Andrea Fletcher, Romney M Humphries, Joanna L Stollings, Adrienne Baughman, Jakea Johnson, Edward T Qian, Mary Lynn Dear, David C Gaston, Ariel A Lewis, George E Nelson, Benjamin J Ereshefsky, Matthew A Christensen, Ritu Banerjee, Dan Albert, Alison Benton, Laura Bobbitt, Carleigh Burns, Timothy Duff, David C. Gaston, MLS Sharon Glover, Allyson Hobbie, Austin Ing, Gabriel Kemp, Sheryl Mangrum, Geoff Mavrak, Kelly Moser, David Mulherin, Shannon Pugh, Matthew Rodgers, Chrissie Schaeffer, Adam Turner, Sabrina Shipman, Halden Z VanCleave, Hamilton Wen Li Wang, LaKeysha Wiggins

“…Introduction Patients with suspected bacterial infection frequently receive empiric, broad-spectrum antibiotics prior to pathogen identification due to the time required for bacteria to grow in culture. …”
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“Arming half-baked people with weapons!” Information enclaving among professionals and the need for a care-centred model for antibiotic use information in Uganda, Tanzania and Malawi by Susan Nayiga, Eleanor E MacPherson, John Mankhomwa, Fortunata Nasuwa, Raymond Pongolani, Rita Kabuleta, Mike Kesby, Russell Dacombe, Shona Hilton, Delia Grace, Nicholas Feasey, Clare I.R. Chandler

“…But while antibiotics are widely available, information on when and how to use them is not. …”
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