A comparison of two systems for group housing of gestating sows - effects on productivity, removal, and treatments by Kaisa Ryytty Sylvén, Torun Wallgren, Pontus Almerheim, Lena Eliasson Selling, Magdalena Jacobson, Per Wallgren

“…Conclusions This study indicated that sows kept in larger groups provided with a larger floor space (a total area of 156 m2, corresponding to 3.9 m2 per sow) and housed on deep straw had a higher number of liveborn and weaned piglets and lower incidence of antibiotic treatments than sows with less floor space (a total area of 24.5 m2, corresponding to 2.5–3.1 m2 per sow) and less bedding/manipulable material.…”
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Cell-associated flagella enhance the protection conferred by mucosally-administered attenuated Salmonella Paratyphi A vaccines. by Orit Gat, James E Galen, Sharon Tennant, Raphael Simon, William C Blackwelder, David J Silverman, Marcela F Pasetti, Myron M Levine

“…<h4>Background</h4>Antibiotic-resistant Salmonella enterica serovar Paratyphi A, the agent of paratyphoid A fever, poses an emerging public health dilemma in endemic areas of Asia and among travelers, as there is no licensed vaccine. …”
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Factors associated with hospital length of stay in patients with thoracic hydatid cyst disease undergoing surgical intervention: a retrospective study by Reza Ershadi, Mohammadreza Salehi, Ghazal Roostaei, Niloofar Khoshnam Rad, Sara Soltanmohammadi, Hesam Amini

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Antibacterial and antibiofilm activities of kaffir lime essential oils and their active constituents against Staphylococcus aureus focusing on sortase A by Chayapol Pontanayodsakorn, Chatchakorn Eurtivong, Pimsumon Jiamboonsri

“…Staphylococcus aureus biofilm has become a global medical concern due to rising antibiotic resistance. This study aimed to evaluate the potential activities of kaffir lime essential oils and their active compounds as alternative anti-S. aureus biofilm agents. …”
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Costs and Outcomes of Clostridioides difficile Infections in Germany: A Retrospective Health Claims Data Analysis by Katharina Schley, Kirstin Heinrich, Jennifer C. Moïsi, Dennis Häckl, Dominik Obermüller, Gordon Brestrich, Christof von Eiff, Thomas Weinke

“…Propensity score matching was conducted on age, sex, comorbidities, and antibiotic use to identify four matched controls (i.e., patients without CDI) for every eligible adult patient with CDI (i.e., case) in the study cohort. …”
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Phenotypic and genotypic screening of multidrug resistant Klebsiella pneumoniae isolated from ready to eat street food in Tanta, Egypt by Hadeer M. Bedair, Mohamed Emara, Shima Mahmoud Ali, Tamer M. Samir, Mahmoud A.F. Khalil

“…Objective This study aimed at evaluating the potential burden of antibiotic-resistant Klebsiella pneumoniae contaminating RTESF and assessing the microbiological quality of RTESF in Egypt. …”
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CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1 by Kamilla Wiull, Lisa K. Haugen, Vincent G. H. Eijsink, Geir Mathiesen

“…An obstacle in developing bacterial delivery vehicles is generating a production strain that lacks antibiotic resistance genes and contains minimal foreign DNA. …”
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EVALUATION OF ANTIBACTERIAL ACTIVITY OF TRICHILIA DREGEANA SOND (MELIACEAE) CRUDE EXTRACTS AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA by Tesfa Mossie, Temesgen Kasa, Bekesis Urge, Hilena Yifred

“…The methanol crude extract of plants is an effective antibacterial agent for treating bacterial infections since the extract showed significant antibacterial potency comparable with that of the standard antibiotic disk. The findings are promising and encourage further investigation of the crude extracts’ phytochemical, toxicological, and pharmacological aspects to support their potential rational use in antimicrobial therapy. …”
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Comparison of chromogenic and cysteine lactose electrolyte deficient agar for identification of uropathogens in Gujarat, India by Nisha Vadivelu, Rashmika D. Parmar, Hitesh Shingala, Krunal D. Mehta

“…Conventional culture techniques, such as cystine lactose electrolyte deficient (CLED) agar, can delay treatment and contribute to inappropriate antibiotic use. Not much is known about alternatives such as chromogenic UTI agar. …”
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Implications of the Intestinal Microbiota in Diagnosing the Progression of Diabetes and the Presence of Cardiovascular Complications by Alina Mihaela Leustean, Manuela Ciocoiu, Anca Sava, Claudia Florida Costea, Mariana Floria, Claudia Cristina Tarniceriu, Daniela Maria Tanase

“…Intestinal microbiota can be modulated by changing one’s lifestyle but also by antibiotic, probiotic, prebiotic, and fecal transplantation. …”
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The periplasmic protein HslJ is the first-line of defense against oxidative stress in Acinetobacter baumannii by Daniela Scribano, Martina Pasqua, Dolores Limongi, Lucia Nencioni, Anna Teresa Palamara, Cecilia Ambrosi

“…Its adaptability to antibiotic resistance and tolerance to various stresses, including reactive oxygen species (ROS), contribute to its persistence in healthcare environments. …”
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Synthesis, Molecular Docking, MEP and SAR Analysis, ADME-Tox Predictions, and Antimicrobial Evaluation of Novel Mono- and Tetra-Alkylated Pyrazole and Triazole Ligands by Y. Kaddouri, B. Bouchal, F. Abrigach, M. El Kodadi, M. Bellaoui, R. Touzani

“…ADME-Tox studies suggested that compounds 12 and 13 exhibit better toxicity profiles than the commercial antibiotic streptomycin. MEP studies suggested that compounds 12 and 13 have the same charge locations but differ in their values which are due to the condensed geometry of compound 13 that make it more polarizable than compound 12. …”
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The Result of Timely Therapy for Whipple's Disease: a Clinical Case by S. N. Mekhtiev, O. A. Mekhtieva, E. Yu. Kalinina, V. E. Karev, A. V. Vanyan, O. M. Berko

“…Timely diagnosis and initiation of antibiotic therapy will help to avoid late complications of the disease, including death.…”
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Adsorption characteristics of metronidazole on CoZr-LDH and its GO nanocomposite: Experimental and theoretical study by Edris Jamshidi, Fateme Fathabadi, Faranak Manteghi, Rahime Eshaghimalekshah

“…CoZr-LDH and its Graphene Oxide (GO) nanocomposite were synthesized by mechanochemical and hydrothermal methods, respectively, and were applied to absorb metronidazole as a pollutant antibiotic from an aqueous solution. In this study, Tetravalent and divalent metal cations were employed. …”
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Never mind the bug: no differences in infection-free survival after periprosthetic joint infections with Staphylococcus aureus, Coagulase-negative Staphylococcus, or Streptococcus by Anders Brüggemann, Nils P. Hailer

“…Infection-free survival was defined as the absence of (1) further surgery to the index joint due to PJI, (2) suppressive antibiotic therapy, and (3) death due to PJI and was assessed using the Kaplan–Meier method. …”
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Risk of Multidrug Resistant Bacteria Acquisition in Patients with Declared β-Lactam Allergy during Hospitalization in Intensive Care Unit: A Retrospective Cohort Study (2007-2018) by Alessio Strazzulla, Maria Concetta Postorino, Nabil Belfeki, Laura Iordache, Astrid de Pontfarcy, Aurelia Pitsch, Pierre Leroy, Sebastien Jochmans, Mehran Monchi, Sylvain Diamantis

“…The study included all patients admitted in ICU and receiving antibiotic treatment from January 2007 to December 2018. …”
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A Case Report of Bowel Perforation in a Gravid COVID-19 Patient by A. T. Guiritan, J. G. Cataluña

“…Patient was eventually intubated and was given a total of two doses of tocilizumab, adequate antibiotic treatment, remdesivir, and dexamethasone. …”
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Potentiation of Doxorubicin Cytotoxicity Utilizing Clarithromycin Loaded-PEGylated Liposomes by Islam Alfreahat MS, Hamdi Nsairat PhD, Ibrahim Deeb Aldeeb PhD, Ali Al-Samydai PhD, Walhan Alshaer PhD

“…Clarithromycin (CAM), a macrolide antibiotic, inhibits multiple metabolic pathways including CYP3A and P-gp, potentially countering DOX resistance. …”
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Prevalence and predictors of small intestinal bacterial overgrowth in inflammatory bowel disease: a meta-analysis by Xin Feng, Jie Hu, Xin Zhang

“…The odds of lower BMI (mean difference = −1.04; 95% CI −1.86 to −0.23), bloating (OR = 3.02, 95% CI 1.22–7.5), flatulence (OR = 4.70, 95% CI 1.44–15.35), history of abdominal surgery (OR = 2.05, 95% CI 1.35–3.11), and stricturing/penetrating disease behavior (OR = 3.51, 95% CI 1.67–7.40) increased significantly in IBD patients with SIBO compared to those without SIBO. Antibiotic treatment may be effective for SIBO in IBD patients.ConclusionNearly one-third of IBD patients present with SIBO positive, and the odds of SIBO in IBD was increased by 5.25-fold compared with healthy controls. …”
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Impact of trachoma elimination efforts in afar regional state, Ethiopia: survey findings from 26 evaluation units by Getachew Gebreselassie, Kasahun Negash, Dawit Woga, Misrak Makonnen, Baye Deneke, Muluken Desalegn, Seada Ali, Colin L. Beckwith, Fentahun Tadesse, Fikre Seife, Genet Kiflu, Fikreab Kebede

“…Conclusion In seven woredas, further rounds of antibiotic mass drug administration are required, complemented by initiatives to promote facial cleanliness and improve environmental conditions. …”
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