Spread of TEM, VIM, SHV, and CTX-M β-Lactamases in Imipenem-Resistant Gram-Negative Bacilli Isolated from Egyptian Hospitals by El sayed Hamdy Mohammed, Ahmed Elsadek Fakhr, Hanan Mohammed El sayed, Said abd Elmohsen Al Johery, Wesam Abdel Ghani Hassanein

“…The isolates were collected from various clinical samples, identified by conventional methods and confirmed by API 20E. Antibiotic susceptibility testing was determined by Kirby-Bauer technique and interpreted according to CLSI. …”
Get full text

Primary pulmonary diffuse large B cell lymphoma presenting with features of organizing pneumonia: a case report by Sunjie Li, Yige Huang, Linlin Wang, Jintao Zhou

“…Case presentation An 81-year-old Chinese man presented with a 4-month history of pulmonary nodules and a 2-month history of cough and dyspnea. Initial empiric antibiotic therapy for suspected lung infection was ineffective. …”
Get full text

Cost–consequence analysis of COPD treatment according to NICE and GOLD recommendations compared with current clinical practice in the UK by Jennifer K Quint, Helene Vioix, Toby Capstick, Sue Langham, Jennifer Cook, Antony Wright, Shamika de Silva

“…Cost savings arose from a reduction in the rates of pneumonia, with an associated decrease in costs associated with antibiotic use and hospitalisation. Savings were achieved overall despite a small increase in the rate of exacerbations due to the redistribution of certain patients currently undergoing triple inhaled therapy to therapies not containing inhaled corticosteroids.Conclusion Redistribution of patients with COPD from current clinical practice to treatment according to published recommendations would provide substantial cost savings over the first year.…”
Get full text

Optimizing chitosan derived from Metapenaeus affinis: a novel anti-biofilm agent against Pseudomonas aeruginosa by Anali Riahi, Hadideh Mabudi, Elahe Tajbakhsh, Laleh Roomiani, Hasan Momtaz

“…The extracted chitosan demonstrated a significant synergistic antibiotic effect against P. aeruginosa when combined with ceftazidime, enhancing its bactericidal activity by up to 15-fold. …”
Get full text

Clinical value of quantitative echocardiographic features in preterm infants with necrotizing enterocolitis by Wenmei li, Wenqiang Sun, Zexi Sun, Huawei Wang, Xueping Zhu

“…Umbilical vein cannulation, antibiotic duration, total red blood cell infusion, duration of total parenteral and total enteral nutrition, respiratory failure, hemodynamically significant patent ductus arteriosus, anemia, neutropenia, hyperbilirubinemia were significantly higher than those in the control group. …”
Get full text

Persistent Chronic Periprosthetic Joint Infection Treated with Three-Stage Revision Hip Arthroplasty: A Case Report by Nurul Ramadian, Jifaldi Afrian Maharaja Dinda Sedar

“…The infecting bacteria is one of the major risk factors, and therefore appropriate antibiotic is important. Augmentation of bone graft can also supplement acetabular bone loss during failed THA as it helps as a scaffold for bone healing. …”
Get full text

Comparative Study of Frequency of Alveolar Osteitis, with and without using Platelet-Rich Fibrin in Mandibular Third Molar Surgery by Maryam Asif, Ahsan Ullah, Hasan Mujtaba, Muhammad Farooq Umer, Zohaib Khurshid

“…Exclusion criteria were patients who were medically compromised, smokers, alcoholic, poor oral hygiene, third molar having associated periapical pathology, and receiving antibiotic regime in the last 2 weeks. Before starting surgical procedure, patients were randomly divided into two groups using lottery method. …”
Get full text

Effects of proton pump inhibitors and histamine-2 receptor antagonists on response to fidaxomicin or vancomycin in patients with Clostridium difficile-associated diarrhoea by Thomas Louie, Karl Weiss, Mark A Miller, Kathleen Mullane, Derrick W Crook, Sherwood L Gorbach

“…However, it is not known whether the use of PPIs or histamine-2 receptor antagonists (H2RAs) concurrently with CDAD-targeted antibiotic treatment affects clinical response or recurrence rates.Design In two phase 3 trials, patients with toxin-positive CDAD were randomised to receive fidaxomicin 200 mg twice daily or vancomycin 125 mg four times daily for 10 days. …”
Get full text

The Incidence of Nosocomial Bloodstream Infections in Children With Congenital Heart Disease Undergoing Cardiac Surgery: A Retrospective Study by Mohammad Mehdi Rajabi, Behdad Gharib, Mohammad Reza Mirzaaghayan

“…Our results highlight the need for stronger infection control measures and targeted antibiotic therapies to effectively manage BSIs. Further research is recommended to validate these results and improve preventive measures in pediatric cardiac units. …”
Get full text

Bacterial and Parasitic Assessment from Fingernails in Debre Markos, Northwest Ethiopia by Abeba Mengist, Yibeltal Aschale, Alemayehu Reta

“…This study was conducted to determine the prevalence of bacteria and intestinal parasites among food handlers and antibiotic susceptibility profile of the isolated bacteria in Debre Markos University, Ethiopia. …”
Get full text

Molecular Detection of Staphylococcal Enterotoxins and mecA Genes Products in Selected Food Samples Collected from Different Areas in Khartoum State by Mohammed Yahya Ahmed, Hashim Abdalbagi Ali, Babbiker Mohammed Taher Gorish, Sara Omer Ali, Eman Saif Aldein Abdalrhim, Mawada Hamza Mergani, Asmaa Abass Abd Elgadir, Somaya Khalid Mohammed, Salma Omer Ahmed, Naglaa Alsaeid Musa, Alaa Saeed Ahmed, Wafaa Mohammed Abdalla, Yousif Fadlallah Hamedelnil, Ahmed Ibrahim Hashim, Hisham N. Altayb

“…Nowadays, many researchers worldwide noted an emergence of resistant strains such as Staphylococci particularly for the antibiotic methicillin. Therefore, this study was aimed to determine the existence of Staphylococcus aureus and its enterotoxins, mecA genes, in selected food samples. …”
Get full text

Effect of a chemically-modified-curcumin on dental resin biodegradation by Qi Dai, Hsi-Ming Lee, Austin Giordano, Fu-Pen Chiang, Stephen G. Walker, Rafael Delgado-Ruiz, Francis Johnson, Lorne M. Golub, Ying Gu

“…Doxycycline achieved similar inhibition by completely eradicating S. mutans with its antibiotic action; hence, it is not recommended for long-term use.…”
Get full text

Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children by Yali Zhang, Yali Zhang, Yingying Xu, Yingying Xu, Ling Hu, Ling Hu, Xiaomei Wang

“…Numerous clinical trials have unequivocally demonstrated that supplementing with probiotics can significantly reduce both the frequency and severity of RRTIs in children while also simultaneously decreasing antibiotic usage. However, there are ongoing controversies and challenges in current research concerning the influence of probiotic type, dosage, duration of use, and other factors on efficacy. …”
Get full text

Diagnosis and management of de novo non-specific spinal infections: European Association of Neurosurgical Societies (EANS) Spine Section Delphi consensus recommendations by Andreas Kramer, Santhosh G. Thavarajasingam, Jonathan Neuhoff, Benjamin Davies, Giuseppe Barbagallo, Bertrand Debono, Bart Depreitere, Sven O. Eicker, Nikolay Gabrovsky, Marisa L. Gandia-Gonzalez, Marcel Ivanov, Radek Kaiser, Stanislav Kaprovoy, Nikolay Konovalov, Jesus Lafuente, Andrzej Maciejczak, Bernhard Meyer, Paulo Pereira, Yana Petrova, Wilco C. Peul, Carla Reizinho, Yu-Mi Ryang, Nico Sampron, Ralph Schär, Enrico Tessitore, Claudius Thomé, Jake Timothy, Carmen Vleggeert-Lankamp, Andreas K. Demetriades, Ehab Shiban, Florian Ringel

“…Minimally invasive surgery (MIS) was endorsed whenever feasible, and a 12 week antibiotic treatment regimen was favored in cases of complicated infections. …”
Get full text

Ribosome pausing in amylase producing Bacillus subtilis during long fermentation by Yaozu Han, Biwen Wang, Alberto Agnolin, Gaurav Dugar, Frans van der Kloet, Christopher Sauer, Paul Igor Costea, Max Fabian Felle, Mathis Appelbaum, Leendert W. Hamoen

“…Results We began by assessing our ribosome profiling procedure using the antibiotic mupirocin that blocks translation at isoleucine codons. …”
Get full text

Antibacterial Activity of Traditional Medicinal Plants Used for the Treatment of Acute Diarrheal Diseases in Chiapas, Mexico by Jesús Mauricio Ernesto Hernández-Méndez, Israel Peña-Hernández, Mariela Tapia-Nazario, Gerardo Leyva-Padrón, Abumalé Cruz-Salomón, María Emperatriz Domínguez-Espinosa, Héctor Armando Esquinca-Avilés, Maritza del Carmen Hernández-Cruz, Rocío Magdalena Sánchez-Albores, Kelly del Carmen Cruz-Salomón, Rosa Isela Cruz-Rodríguez, Martha Guadalupe Gómez-Santos

“…The <i>Enterobacteriaceae</i> family poses health risks due to its role in gastrointestinal diseases like acute diarrhea. With rising antibiotic resistance, plants offer promising antibacterial compounds with low toxicity. …”
Get full text

Isolation and Characterization of Colistin-Resistant <i>Enterobacteriaceae</i> from Foods in Two Italian Regions in the South of Italy by Rosa Fraccalvieri, Angelica Bianco, Laura Maria Difato, Loredana Capozzi, Laura Del Sambro, Stefano Castellana, Adelia Donatiello, Luigina Serrecchia, Lorenzo Pace, Donatella Farina, Domenico Galante, Marta Caruso, Maria Tempesta, Antonio Parisi

“…Furthermore, 56 antimicrobial resistance genes were identified, suggesting the genetic mechanisms underlying resistance to several antibiotic classes. Virulence gene analysis showed that <i>E. coli</i> and other isolates carried genes linked to pathogenicity, increasing the potential risk to public health. …”
Get full text

Metabolites Profiling of Soil Actinomycetes with Antimicrobial and Anticancer Activities by Ram Prabodh Yadav, Bibek Raj Bhattarai, Rabin Budhathoki, Padamlal Budthapa, Monika Rana, Rubin Thapa Magar, Bijaya Bahadur Thapa, Akkal Dev Mishra, Niranjan Parajuli

“…Gas Choursomatography-Mass Spectrometry (GC-MS) analysis revealed particularly volatile chemical constituents in the extracts. Antibiotic agents such as diketopiperazines and hexahydropyrrolo[1,2-a]pyrazine-1,4-dione were prevalent in the extracts of these isolates. …”
Get full text

The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers by Giulia Solazzo, Sabrina Rovelli, Simona Iodice, Matthew Chung, Michael Frimpong, Valentina Bollati, Luca Ferrari, Elodie Ghedin

“…Additionally, both indoor and outdoor TSP samples contained broad spectrum antibiotic resistance genes. Indoor TSP exposure was negatively associated with commensal bacteria and positively associated with Staphylococcus aureus relative abundance. …”
Get full text

Evaluating the risk of acute kidney injury and mortality associated with concomitant use of vancomycin with piperacillin/tazobactam or meropenem in critically ill and non-criticall... by Abdulmajeed M. Alshehri, Majed S. Al Yami, Atheer Aldairem, Lama Alfehaid, Abdulaali R. Almutairi, Omar A. Almohammed, Amal Mohammad Badawoud

“…Conclusion The findings suggest that the use of VPT is associated with a higher risk of AKI compared to VM and highlight the need for cautious antibiotic selection and monitoring of renal function in patients receiving these combinations.…”
Get full text