Streptococcal periorbital necrotizing fasciitis: Case series on a rare but potentially life-threatening entity by Isabella D. Baur, Isabel Habert, Monica Markstaller, Kathrin Hartmann, Arthur Mueller

“…We performed early and consequent debridement of necrotic tissue to control the infection alongside adequate systemic antibiotic therapy including clindamycin in all cases of suspected NSTI. …”
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Atypical Sjögrenʼs Syndrome Initially Presenting as Lymphocytic Interstitial Pneumonitis followed by Immune Thrombocytopenia by Maham Mehmood, Abhishrut Jog, Masooma Niazi, Arlene Tieng, Giovanni Franchin

“…Laboratory studies revealed hemoglobin of 11.9 g/dL, white blood cell count of 16,000/uL, and platelet count of 250,000/uL. Empiric antibiotic therapy was begun for suspected community acquired pneumonia, and then he was discharged home. …”
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Using the Sleeping Beauty Transposon System for Doxycycline-inducible Gene Expression in RAW264.7 Macrophage Cells to Study Phagocytosis by Parsa Kamali, Gregory Fairn

“…Experimentally, the system introduces two plasmids: one carrying the Sleeping Beauty transposase and the other with an integration cassette carrying the gene of interest, a reverse-doxycycline controlled repressor gene, and an antibiotic resistance gene. The construct used in this protocol provides puromycin resistance. …”
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Prosthetic Joint Infection Trends at a Dedicated Orthopaedics Specialty Hospital by Robert P. Runner, Amanda Mener, James R. Roberson, Thomas L. Bradbury, George N. Guild, Scott D. Boden, Greg A. Erens

“…These results suggest a change in the microbiologic profile of PJI when transitioning to a dedicated orthopaedic facility and that greater Gram-negative antibiotic coverage could be considered.…”
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The use of human antiretroviral drugs (ARVs) in broiler chicken and domestic pig farming in Tanzania by Zuhura I. Kimera, Emmanuel C. Balandya, Mecky I. N. Matee, Lisa V. Adams

“…Conclusion High usage of veterinary, human, and other medicines, including ARVs, in animal production predisposes the Tanzanian community to public health threats, including antibiotic and antiretroviral resistance. We recommend implementing urgent mitigation strategies to control the misuse of human ARVs in animal production.…”
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Development and Optimization of a Nanoparticle-Based Imidacloprid Insecticide for Effective Control of Blattella germanica by Ismael Saba, Amir Amani, Mozhgan Baniardalani, Hamidreza Basseri

“…Blattella germanica threatens human health by producing asthma-inducing allergens, carrying pathogenic/antibiotic-resistant microbes, and contributing to unhealthy indoor environments. …”
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Association between maternal rectovaginal group B streptococcus and the risk of stillbirth: a meta-analysis by Yujue Wang, Jingjing Liu, Jinlian Song, Teng Zhang

“…However, sensitivity analyses revealed a significant association in studies that included intrapartum antibiotic prophylaxis (IAP) (OR: 1.36, 95% CI [1.02–1.80], p = 0.03). …”
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DJK-5, an anti-biofilm peptide, increases Staphylococcus aureus sensitivity to colistin killing in co-biofilms with Pseudomonas aeruginosa by Samuel J. T. Wardell, Deborah B. Y. Yung, Anupriya Gupta, Mihnea Bostina, Joerg Overhage, Robert E. W. Hancock, Daniel Pletzer

“…We investigated the efficacy of combining the last-line antibiotic colistin with a membrane- and stringent stress response-targeting anti-biofilm peptide DJK-5 against co-biofilms comprised of multidrug-resistant P. aeruginosa and methicillin-resistant S. aureus (MRSA). …”
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Microbiological Profile of Neonatal Sepsis at a Maternity Hospital in Omdurman, Sudan by Manal Abdelaziz, Yassir Hamadalnil, Omaima Hashim, Tahane Bashir, E. S. Mahjoub

“…The best choice for treatment is Vancomycin (8.4%) and Imepenem (2.7%) for gram-positive and gram-negative, respectively. Adherence to antibiotic policy, antimicrobial surveillance, and policy updating is necessary.…”
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Oral Lichen Planus and Lichenoid Lesions in Sjogren’s Syndrome Patients: A Prospective Study by Raouaa Belkacem Chebil, Yassine Oueslati, Marwa Marzouk, Fatma Ben Fredj, Lamia Oualha, Nabiha Douki

“…OLP lesions showed improvement in symptoms after topical or general corticosteroids treatment, while OLL showed improvement only under antibiotic treatment. Conclusion. The results of our analysis suggest that patients with SS have 30% prevalence of OLP and OLL. …”
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Pathobiology of Helicobacter pylori Infection in Children by Robert H Riddell

“…Some diseases, particularly Crohn’s disease, but also human immunodeficiency virus infection, have a negative association with H pylori that appears not to be simply a result of the excess antibiotic therapy that these patients receive. These variations in association and reactions to H pylori, some of which are age-related, may allow the different host responses to H pylori that occur in humans to be examined.…”
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First report of MDR virulent Pseudomonas aeruginosa in apparently healthy Japanese quail (Coturnix japonica) in Bangladesh. by Alamgir Hasan, Md Tanjir Ahmmed, Bushra Benta Rahman Prapti, Aminur Rahman, Tasnim Islam, Chandra Shaker Chouhan, A K M Anisur Rahman, Mahbubul Pratik Siddique

“…Bacterial isolation and identification were performed using cultural, morphological, biochemical, and polymerase chain reaction (PCR) methods. Antibiotic susceptibility was assessed using the disc diffusion method, and virulence genes were detected through PCR. …”
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Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties by Ling Yien Ing, Noraziah Mohamad Zin, Atif Sarwar, Haliza Katas

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Clinical Profile and Risk Factors of Group B Streptococcal Colonization in Mothers from the Eastern District of China by Jin Jiao, Weiwei Wu, Feng Shen, Zhongyuan Liu, Huiru Zhou, Gang Fan, Yuxia Zhou

“…Penicillin could still be used as the first agent of choice for intrapartum antibiotic prophylaxis (IAP).…”
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Coexistence of Virulence Factors and Efflux Pump Genes in Clinical Isolates of Pseudomonas aeruginosa: Analysis of Biofilm-Forming Strains from Iran by Shahram Shahraki Zahedani, Hamed Tahmasebi, Mojdeh Jahantigh

“…Biofilm formation and efflux pumps (EPs) correlation play a critical role in the pathogenicity and antibiotic resistance of Pseudomonas aeruginosa. In this study, biofilm formation and EP’s collaborative role in clinical isolates of P. aeruginosa infection were investigated. …”
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Understanding transmission pathways and integrated digital surveillance potential of antimicrobial resistance in Ethiopia in a One Health approach: a mixed-method study protocol by Muhammad Asaduzzaman, Christoph Gradmann, Andrea Sylvia Winkler, Zeleke Mekonnen, Ernst Kristian Rodland

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Vancomycin population pharmacokinetic models: Uncovering pharmacodynamic divergence amid clinicobiological resemblance by Peggy Gandia, Sahira Chaiben, Nicolas Fabre, Didier Concordet

“…Abstract Vancomycin is an antibiotic used for severe infections. To ensure microbiological efficacy, a ratio of AUC/MIC ≥400 is recommended. …”
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Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department by John E. Schneider, Jonathan Romanowsky, Philipp Schuetz, Ivana Stojanovic, Henry K. Cheng, Oliver Liesenfeld, Ljubomir Buturovic, Timothy E. Sweeney

“…Reductions in hospital days (-0.80 days, -36.7%), antibiotic days (-1.49 days, -29.5%), and percent 30-day mortality (-1.67%, -13.64%) were driven by HostDx Sepsis providing fewer “noninformative” moderate risk predictions and more “certain” low- or high-risk predictions compared to standard of care, especially for patients who were not severely ill. …”
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Seminoma of Testis Masquerading as Orchitis in an Adult with Paraplegia: Proposed Measures to Avoid Delay in Diagnosing Testicular Tumours in Spinal Cord Injury Patients by Subramanian Vaidyanathan, Peter L. Hughes, Paul Mansour, Bakul M. Soni

“…To prevent delay in the diagnosis of testicular tumours in SCI patients, we propose the following measures: (1) patients who develop swelling of the testis should consult a physician as soon as possible for clinical examination; blind antibiotic therapy should be avoided if possible; (2) if clinical examination reveals a hard swelling of the testis and the typical features of acute urinary infection are absent, an ultrasound scan of the scrotum should be performed as soon as possible; (3) in patients with equivocal ultrasound findings, ultrasound-guided, fine-needle aspiration cytology may allow an early diagnosis of testicular malignancy; (4) education of SCI patients and their caregivers is needed to implement these recommendations.…”
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Antimicrobial Peptides from Porcine Blood Cruor Hydrolysates as a Promising Source of Antifungal Activity by Sara García-Vela, Aurore Cournoyer, Zain Sánchez-Reinoso, Laurent Bazinet

“…AMPs can exhibit both antibacterial and/or antifungal properties, thus improving food safety and addressing the growing concern of antibiotic and antifungal resistance. The objective of this study was to evaluate the antimicrobial activity of potential AMPs previously identified from porcine cruor hydrolysates. …”
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