Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates by Charlotte Michel, Fedoua Echahidi, Geraldine De Muylder, Max Sewell, Ian Boostrom, Olivier Denis, Owen B. Spiller, Denis Pierard

“…Although Legionella pneumophila is known as pathogenic, systematic investigations into antibiotic resistance are scarce, and reports of resistance in isolates are recently emerging. …”
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Risk of infection and conversion time from external to definitive fixation in open tibial fracture by Wazzan S. Aljuhani, Yasir A. Alshabi, Abdullah M. Alanazi, Meshal A. Alothri, Saleh A. Almutairi, Ziad A. Aljaafri, Abdullah M. Alzahrani

“…However, no association was observed between infection and antibiotic duration or initial debridement time (P = 0.689 and P = 0.963, respectively). …”
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The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) by V. T. Ivashkin, O. P. Alekseyeva, A. Yu. Baranovsky, Ye. K. Baranskaya, Ye. V. Beloborodova, T. A. Kolesov, N. V. Korochanskaya, K. . Lang, T. L. Lapina, I. V. Mayev, M. V. Mokshina, D. L. Nepomnyashchy, Ye. V. Onuchina, R. G. Sayfutdinov, T. H. Sviridova, V. I. Simanenkov, A. V. Tkachev, A. S. Trukhmanov, L. P. Faizova, I. B. Khlynov, O. B. Khlynova, A. A. Sheptulin

“…Potential of PylopassTM combination to various H. pylori eradication therapy modes is a subject offutnet multicenter randomized clinical trials for assessment of optimal combination to antibiotic drugs, treatment duration and adverse effect rates. …”
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Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy by Benjamine Lapras, Camille Merienne, Emma Eynaud, Léa Usseglio, Chloé Marchand, Mathieu Médina, Camille Kolenda, Thomas Briot, Frédéric Laurent, Fabrice Pirot, PHAGEinLYON

“…Abstract Phage therapy uses viruses (phages) against antibiotic resistance. Tailoring treatments to specific patient strains requires stocks of various highly concentrated purified phages. …”
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Prospects of betulin application in broiler farming by M. V. Novikova, I. A. Lebedeva, L. I. Drozdova, A. V. Byuler

“…It is an urgent task today to seek and implement nature-like technologies in broiler production and obtain biologically complete and safe poultry products, thus refusing from antibiotic use in feed. Feed additives based on natural components can be an effective tool for implementation of preventive and therapeutic veterinary measures. …”
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Fecal Microbiota Transplantation: A Systematic Review of Therapeutic Potential, Preparation Techniques, and Delivery Methods Across Medical Conditions by Syamand Ahmed Qadir, Qausar Hamed ALKaisy, Abdulbasit F. Hasan, Farhang Hameed Awlqadr, Ammar B. Altemimi, Aryan Mahmood Faraj, Angelo Maria Giuffrè, Mohammed N. Saeed, Sherzad Rasul Abdalla

“…FMT has demonstrated high success rates, particularly in treating recurrent and refractory Clostridium difficile infections (CDI), with up to 90% effectiveness, establishing it as a primary treatment for antibiotic-resistant cases. FMT’s applications are expanding to inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, as well as metabolic disorders and neuropsychiatric conditions. …”
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Synthesis, crystal structure, hirshfeld study, DFT analysis, molecular docking study, antimicrobial activity of β-enaminonitrile bearing 1H-pyran by Al-Anood M. Al-Dies, Fawzia F. Alblewi, Rawda M. Okasha, Mosa H. Alsehli, Rita M. A. Borik, Saleh Ihmaid, Abd El-Galil E. Amr, Hazem A. Ghabbour, Ahmed A. Elhenawy, Ahmed M. El-Agrody

“…Compound 4 was screened for its antimicrobial capability against three Gram-positive, three Gram-negative bacteria, and three fungi, utilizing the reference antibiotic drug Ampicillin, Gentamycin, and Ketoconazole. …”
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Clostridium Scindens Protects Against Vancomycin‐Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR‐FGF15/19 Signaling by Jintao Xiao, Yanliang Hou, Xingyang Luo, Yuhao Zhu, Wenhu Li, Bingbing Li, LinXiang Zhou, Xia Chen, Ying Guo, Xiaomei Zhang, Haiyue He, Xiaowei Liu

“…Vancomycin, a glycopeptide antibiotic, has emerged as a promising candidate. However, the mechanism by which vancomycin impacts the progression of PSC remains unknown. …”
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Differences in the effects and action modes of gut commensals against dextran sulfate sodium-induced intestinal inflammation by Dingwu Qu, Zhennan Gu, Saisai Feng, Leilei Yu, Fengwei Tian, Hao Zhang, Wei Chen, Qixiao Zhai

“…Interestingly, B. breve JSNJJNM2 with high anti-inflammatory potential in the MLN model could relieve colitis symptoms in antibiotic cocktail (Abx)-treated mice. Meanwhile, E. faecalis FJSWX25M1 induced low levels of cytokines in vitro and showed no beneficial effects. …”
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Novel derivative of nicotinic acid ameliorates doxorubicin-induced cardiac injury via regulation of redox homeostasis by Yana V. Loboda, Mikhail V. Korokin, Alexey V. Kuznetsov, Tatiana N. Malorodova, Anton P. Danilenko, Anna A. Peresypkina, Oleg S. Gudyrev, Ol’ga A. Kop’eva, Tatyana G. Pokrovskaya, Liliya V. Korokina, Valeriya N. Khruslova, Valeriya A. Nazarenko, Tatyana V. Avtina, Alexey V. Deikin, Aleksandr A. Dolzhikov, Tatiana V. Puzanova, Lyudmila M. Danilenko

“…Introduction: Doxorubicin (DOX) is an anthracycline antibiotic with considerable significance in clinics as an anticancer agent, which is limited by its cardiotoxicity, though. …”
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Cystitis glandularis due to Escherichia coli infection in a diabetic Miniature Schnauzer: a case report by J. P. Rey Amunategui, D. Echeverria, A. Duchene

“…After initiation of antibiotic therapy and pain management, the dog's clinical signs improved markedly until complete remission of the bladder lesions. …”
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Attitudes of healthcare workers at a District in KwaZulu-Natal regarding institutionalisation of antimicrobial stewardship by Andile P. Dlungele, Lehlohonolo J. Mathibe

“…Eighty percent (n = 40; median score 5, interquartile range [IQR] 4–5) and 67% (n = 33; median score 4, IQR 3–4) of participants felt that they had a key role in reducing antibiotic resistance; and good knowledge of antimicrobials as well as AMS programmes, respectively. …”
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Implementation and evaluation of a complex outpatient oral antimicrobial therapy program (COpAT) in Canada by Maggie Wong, Davie Wong

“…Twenty-two patients developed an adverse reaction, of which three required a change in therapy and one resolved with antibiotic dose reduction. No C. difficile infections or mortality were reported 30-days post COpAT discharge. …”
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Dereplication of Natural Product Antifungals via Liquid Chromatography–Tandem Mass Spectrometry and Chemical Genomics by Nathaniel J. Brittin, David J. Aceti, Doug R. Braun, Josephine M. Anderson, Spencer S. Ericksen, Scott R. Rajski, Cameron R. Currie, David R. Andes, Tim S. Bugni

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Rifaximin versus Nonabsorbable Disaccharides for the Treatment of Hepatic Encephalopathy: A Meta-Analysis by Dong Wu, Shu-Mei Wu, Jie Lu, Ying-Qun Zhou, Ling Xu, Chuan-Yong Guo

“…Many studies have found that the antibiotic rifaximin is effective for the treatment of hepatic encephalopathy. …”
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Decomposition of the pangenome matrix reveals a structure in gene distribution in the Escherichia coli species by Siddharth M. Chauhan, Omid Ardalani, Jason C. Hyun, Jonathan M. Monk, Patrick V. Phaneuf, Bernhard O. Palsson

“…This approach reveals the genetic basis for differential traits across phylogroups, offering insights into pathogenicity, antibiotic resistance, and evolutionary adaptations. …”
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An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH by Claire Healy, Sabine Ehrt, Alexandre Gouzy

“…This study reveals an unexpected role of the Pi starvation response in regulating acid growth arrest and highlights the intricacy of the mechanisms regulating redox homeostasis, acid stress response, and nutrient utilization in Mtb.IMPORTANCEDespite the availability of antibiotic treatment, M. tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a major infectious disease killer worldwide. …”
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PREDISPOSITION FACTORS ANALYSIS FOR FOURNIER'S GANGRENE DEFECTS CLOSURE COMPLICATION by Bayu Fasi Bermani, Sitti Rizaliyana, Ira Handriani

“…All patients received broad-spectrum antibiotic therapy, and extensive surgical excision. …”
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Dermatologic Adverse Events Following Afatinib in a Woman with Non-Small-Cell Lung Cancer: A Case Report by Tsaqilah L, Putri AD, Avriyanti E

“…The administration of afatinib was continued and the patient was treated with moisturizer, sunscreen, and mild cleanser, topical antibiotic, and topical steroid along with oral doxycycline and oral cetirizine for four weeks. …”
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Estimating the Risk of Maternal Death at Admission: A Predictive Model from a 5-Year Case Reference Study in Northern Uganda by Gasthony Alobo, Cristina Reverzani, Laura Sarno, Barbara Giordani, Luigi Greco

“…This calls for prompt and better assessment of referred mothers and specific attention to antibiotic therapy before and after caesarean section, especially among HIV-positive women.…”
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