Corneal Subbasal Nerve Recovery in an Acute Case of Ultraviolet Keratitis Treated with Autologous Serum Eye Drops by Farshad Abedi, Pedram Hamrah

“…She was initially started on antibiotic ointment and lubricant eye drops. On her follow-up visit 3 days later, corneas had persistent SPK bilaterally. …”
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From Bench to Bedside to Bug: An Update of Clinically Relevant Advances in the Care of Persons with Helicobacter pylori Associated Diseases by N Chiba, ABR Thomson, P Sinclair

“…The one-week proton pump inhibitor-based triple regimens remain the gold standard of H pylori therapy, but some of the ranitidine bismuth citrate plus two antibiotic regimens also achieve an 80% H pylori eradication rate on an intention-to-treat basis. …”
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Comparative analysis of qPCR and metagenomics for detecting antimicrobial resistance in wastewater: a case study by William Taylor, Kristin Bohm, Kristin Dyet, Louise Weaver, Isabelle Pattis

“…While AMR surveillance of human clinical isolates is well-established in many countries, the increasing threat of AMR has intensified efforts to detect antibiotic resistance genes (ARGs) accurately and sensitively in environmental samples, wastewater, animals, and food. …”
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Enhanced Isolation of Streptomyces from Different Soil Habitats in Calamba City, Laguna, Philippines using a Modified Integrated Approach by Jhon Wilson A. Antido, Fresthel Monica M. Climacosa

“…Streptomyces species are considered to be the most prolific sources of various bioactive secondary metabolites that are important for antibiotic production. Here, we describe a modified integrated approach to isolate Streptomyces species from diverse soil habitats, such as dumpsite, garden, forest, grassland, and riverside in Calamba City, Laguna, Philippines. …”
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New Bioactive Metabolites from the Thermophilic Fungus Penicillium sp. Isolated from Ghamiqa Hot Spring in Saudi Arabia by Raha Orfali, Shagufta Perveen

“…All isolated metabolites were studied for their antibiotic effect against several pathogenic bacteria and for their cytotoxicity against the lymphoma human cancer cell line HTB-176. …”
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Characterization of Enterobacter phage vB_EcRAM-01, a new Pseudotevenvirus against Enterobacter cloacae, isolated in an urban river in Panama. by Ednner E Victoria-Blanco, Jean Pierre González-Gómez, Juan Raúl Medina-Sánchez, Alexander A Martínez, Nohelia Castro Del Campo, Cristóbal Chaidez-Quiroz, Jordi Querol-Audi, Alex Omar Martínez-Torres

“…The Enterobacter cloacae complex, a prominent bacterium responsible worldwide for most bloodstream infections in the hospital environment, has shown broad-spectrum antibiotic resistance, including carbapenems. Therefore, bacteriophages have again attracted the attention of the science and medical community as an alternative to control Multidrug resistant bacteria. …”
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Retained multiple contact lenses in a vulnerable dementia patient by Rohit SHARMA, Zuhair SHARIF

“…Treated ‘on and off ’ by various doctors and healthcare professionals with antibiotic drops for eight months with no improvement. …”
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Noninvasive Monitoring of Pneumococcal Meningitis and Evaluation of Treatment Efficacy in an Experimental Mouse Model by Jagath L. Kadurugamuwa, Kshitij Modi, Jun Yu, Kevin P. Francis, Carlos Orihuela, Elaine Tuomanen, Anthony F. Purchio, Pamela R. Contag

“…Mice treated with the antibiotic survived infection, whereas all mice in untreated groups became moribund, first in the IC group then in the LP group. …”
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The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. by Catherine B Reynolds, Jenny E Emerson, Lucia de la Riva, Robert P Fagan, Neil F Fairweather

“…Clostridium difficile is the main cause of antibiotic-associated diarrhea, leading to significant morbidity and mortality and putting considerable economic pressure on healthcare systems. …”
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Development of a broad-spectrum epitope-based vaccine against Streptococcus pneumoniae. by Md Nahian, Muhammad Shahab, Md Rasel Khan, Shopnil Akash, Tanjina Akhtar Banu, Murshed Hasan Sarkar, Barna Goswami, Sanjana Fatema Chowdhury, Mohammad Ariful Islam, Ahmed Abu Rus'd, Shamima Begum, Ahashan Habib, Aftab Ali Shaikh, Jonas Ivan Nobre Oliveira, Shahina Akter

“…Available pneumonia vaccines have limitations since they only cover particular serotypes and have high production costs. The emergence of antibiotic-resistant SPN strains further underscores the need for a new, cost-effective, broad-spectrum vaccine. …”
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PhoU homologs from Staphylococcus aureus dimerization and protein interactions by Clayton T. Matthews, Sakib Mahmud, Stewart G. Gardner

“…ABSTRACT PhoU proteins are negative regulators of the phosphate response, regulate virulence, and contribute to antibiotic resistance. Staphylococcus aureus has multiple genes encoding PhoU homologs that regulate persister formation and potentially virulence, but the molecular mechanisms of this regulation are not fully understood. …”
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Effect of Ozone Gel on Postoperative Sequelae after Surgical Removal of Impacted Lower Third Molars. by Sherwan Faisal Hamadamin, Ahmad Abdulla Haider

“…Methods: the current study enrolled 50 patients divided randomly in to two equal groups, Group I (study group) received ozone gel intra-socket and oral placebo postoperatively and Group II (control group) received a systemic antibiotic. Clinical examination includes assessment of maximal mouth opening on the day of surgery, panoramic x-ray was used for evaluation of the location and configuration of impacted lower third molars, surrounding bone, mandibular canal and adjacent tooth. …”
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Optimized Synthesis of Magnesium Oxide Nanoparticles as Bactericidal Agents by Mohammad Moslem Imani, Mohsen Safaei

“…Increased antibiotic resistance of microorganisms as well as the need to reduce health-care costs necessitates the production of new antimicrobials at lower costs. …”
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The N-terminus of the Clostridioides difficile transferase A component directs toxin activity and potency by Robin M. Mullard, Michael J. Sheedlo

“…ABSTRACT Clostridioides difficile infection is the leading cause of antibiotic-associated, hospital-acquired diarrhea in the USA; the pathology of which is mediated by toxins. …”
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Multidrug Resistance and Plasmid Profiles of Escherichia coli Isolated from Lebanese Broiler Farms by Houssam Shaib, Paul Aoun, Ahmad Ghaddar, Hamza Al Labadi, Youssef Obeid

“…The best-performing antibiotic families were Carbapenems (Imipenem) and Quinolones (Ciprofloxacin and Norfloxacin) to which only 0.0 and 8.3% of the isolates were resistant, respectively. …”
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Clinical-epidemiological study on Fournier's gangrene in a Luanda hospital. From January 2016 to December 2021 by Tomas Ariel Lombardo Vaillant

“…Pain with increased scrotal volume predominated in 43 (67.2%) subjects; early surgical debridement with antibiotic therapy was the key to management. Five patients died. …”
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Environmental Metagenomic Analysis of "ESKAPE" Pathogens in the Pediatric Intensive Care Unit of General Hospital Yogyakarta Indonesia by Ludhang Pradipta Rizki, Indah Kartika Murni, Abu Tholib Aman, Titik Nuryastuti

“…Noteworthy findings include resistome genes characterized by mechanisms like efflux pumps (MDR) and alterations in antibiotic targets. …”
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Nutritional Interventions May Improve Outcomes of Patients Operated on for Diabetic Foot Infections: A Single-Center Case-Control Study by Ilker Uçkay, Vinoth Yogarasa, Felix W. A. Waibel, Annette Seiler-Bänziger, Maja Kuhn, Margrit Sahli, Martin C. Berli, Benjamin A. Lipsky, Madlaina Schöni

“…DFI cases who had professional nutritionists’ interventions had a significantly shorter hospital stay, had shorter antibiotic therapies, and tended to fewer surgical debridements. …”
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Efficacy of Contezolid in the Treatment of Catheter-Related Bloodstream Infections Caused by Methicillin-Resistant Staphylococcus aureus in a Patient with Hepatorenal Syndrome and... by Zhang X, Huang H, Wang J, Wei B

“…To address this complex clinical challenge, a novel oxazolidinone antibiotic, contezolid (800mg orally every 12 hours), was introduced into the patient’s anti-infection regimen. …”
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Molecular Characterization of Staphylococci Recovered from Hospital Personnel and Frequently Touched Surfaces in Tianjin, China by Yuting Liu, Liqin Chen, Yuping Duan, Zhen Xu

“…One hundred and ninety-five staphylococci were recovered, and 94% of isolates were resistant to at least one antibiotic. Eighty-five staphylococci were mecA gene-positive, and 40% of them harbored SCCmec IV and V. …”
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