Isolation of Bacillus sphaericus from Lombok Island, Indonesia, and Their Toxicity against Anopheles aconitus by Bambang Fajar Suryadi, Bagyo Yanuwiadi, Tri Ardyati, Suharjono

“…Suspension was heat-shocked at 80°C for 30 minutes and then spread onto antibiotic-supplemented NYSM solid medium. Colonies grown were characterized and subjected to initial toxicity test against anopheline larvae. …”
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Metagenomic insights into pathogenic bacteria and antimicrobial resistance in offshore coastal sediments – An example from Gulf waters by Nazima Habibi, Saif Uddin, Hanan Al Sarawi, Ahmad Aldhameer, Montaha Behbehani, Saja Fakhraldeen, Waleed Al-Zekri, Nasreem Abdulrazzack, Farhana Zakir, Anisha Shajan

“…Globally, indiscriminate waste discharges in marine environments are one of the key contributors to pathogenic bacteria, antibiotic resistance genes (ARGs), and mobile genetic elements (MGEs). …”
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Development and Validation of a Decision-Making Stratification Algorithm to Optimize the Use of Rapid Diagnostic Testing for Patients with Staphylococcus Bacteremia by Thamer A. Almangour, Abdullah A. Alhifany, Deanne E. Tabb

“…The average expected time avoided to optimize antibiotic therapy is 35±16 hours. If the QuickFISH test had been indiscriminately implemented for all cases, the cost for performing this test would have been $5,590. …”
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Isolation and Identification of Methicillin-Resistant Staphylococcus aureus (MRSA) from Milk in Shire Dairy Farms, Tigray, Ethiopia by Weldemelak Girmay, Getachew Gugsa, Habtamu Taddele, Yisehak Tsegaye, Nesibu Awol, Meselu Ahmed, Aklilu Feleke

“…Antibiotic-resistant Staphylococcus aureus isolates pose a severe challenge to both veterinary and health professions and dairy cattle producers. …”
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Improving Geldanamycin Production in <i>Streptomyces geldanamycininus</i> Through UV Mutagenesis of Protoplast by Yuan Yuan, Lu Yang, Zhikai Fang, Haimin Chen, Fei Sun, Hong Jiang, Jian Zhou

“…Geldanamycin, a benzoquinone ansa antibiotic, has been extensively applied in medical, agricultural, and health research areas due to its antitumor, antifungal, herbicidal, and antiradiation effects. …”
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Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism by Simon Nicolas, Vincent Blasco‐Baque, Audren Fournel, Jerome Gilleron, Pascale Klopp, Aurelie Waget, Franck Ceppo, Alysson Marlin, Roshan Padmanabhan, Jason S Iacovoni, François Tercé, Patrice D Cani, Jean‐François Tanti, Remy Burcelin, Claude Knauf, Mireille Cormont, Matteo Serino

“…To investigate this question, we transferred caecal microbiota from either obese or lean mice to antibiotic‐free, conventional wild‐type mice. We found that transferring obese‐mouse gut microbiota to mice on normal chow (NC) acutely reduces markers of hepatic gluconeogenesis with decreased hepatic PEPCK activity, compared to non‐inoculated mice, a phenotypic trait blunted in conventional NOD2 KO mice. …”
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Epidemiology and Genetic Diversity of Colistin Nonsusceptible Nosocomial Acinetobacter baumannii Strains from Russia for 2013-2014 by Eugene A. Sheck, Mikhail V. Edelstein, Marina V. Sukhorukova, Natali V. Ivanchik, Elena Yu. Skleenova, Andrey V. Dekhnich, Ilya S. Azizov, Roman S. Kozlov

“…This article presents the epidemiological features and genetic diversity of colistin nonsusceptible A. baumannii strains collected as part of a national multicenter epidemiological study of the antibiotic resistance of pathogens of nosocomial infections (MARATHON), which was conducted in 2013-2014 in Russia. …”
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Granulomatous Lung Disease Requiring Mechanical Ventilation Induced by a Single Application of Oxaliplatin-Based Chemotherapy for Colorectal Cancer: A Case Report by Dane Wildner, Frank Boxberger, Axel Wein, Kerstin Wolff, Heinz Albrecht, Gudrun Männlein, Rolf Janka, Kerstin Amann, Jürgen Siebler, Werner Hohenberger, Markus F. Neurath, Richard Strauß

“…Despite high-dose empiric antibiotic and antimycotic treatment, no clinical improvement was seen. …”
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Neutropenic Sepsis in the ICU: Outcome Predictors in a Two-Phase Model and Microbiology Findings by Jan M. Kruse, Thomas Jenning, Sibylle Rademacher, Renate Arnold, Clemens A. Schmitt, Achim Jörres, Philipp Enghard, Michael Oppert

“…Ineffective initial antibiotic therapy, fungal infections, and detection of multiresistant bacteria displayed a particularly poor outcome. …”
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Antibacterial potential of celery (Apium graveolens L.) extract gel against Staphylococcus aureus by Martinus Ezra Sunarno, Anita Lidesna Shinta Amat, Arley Sadra Telussa, Prisca Deviani Pakan

“…Conventional topical therapies often lead to side effects such as contact dermatitis and pruritus, compounded by the increasing problem of antibiotic resistance. Natural ingredients like celery (Apium graveolens L.) offer promising alternatives due to their antibacterial properties and gentler effects. …”
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Uncovering the genetic basis of antiviral polyketide limocrocin biosynthesis through heterologous expression by Sofiia Melnyk, Marc Stierhof, Dmytro Bratiichuk, Franziska Fries, Rolf Müller, Yuriy Rebets, Andriy Luzhetskyy, Bohdan Ostash

“…Abstract Background Streptomyces roseochromogenes NRRL 3504 produces clorobiocin, an aminocoumarin antibiotic that inhibits DNA replication. No other natural products have been isolated from this bacterium so far, despite the presence of a rich repertoire of specialized metabolite biosynthesis gene clusters (smBGCs) within its genome. …”
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The complexities of elexacaftor/tezacaftor/ivacaftor therapeutic drug monitoring in a person with cystic fibrosis and Mycobacterium abscessus pulmonary disease by Claire Y Mou, Daniel J Henderson, Angela G Matson, Karen M Herd, David W Reid, Timothy Riddles, Ellie Johnson, Brett McWhinney, Rebecca Swenson, Andrew Burke, Ieuan E S Evans

“…Utilising National Association of Testing Authorities (NATA) accredited assays and target considerations published by the Therapeutic Goods Administration (TGA), Australia, ETI plasma concentration variability was monitored over the course of an acute admission with added complexity from an antibiotic regimen including rifabutin, a moderate cytochrome P450 3A (CYP3A) inducer, and clofazimine, a mild CYP3A inhibitor. …”
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Amodiaquine and Ciprofloxacin Combination in Plasmodiasis Therapy by Peace Mayen Edwin Ubulom, Chinweizu Ejikeme Udobi, Mark Iheukwumere Madu

“…Amodiaquine (a known antiplasmodial agent) had a fairly significant antiplasmodial effect reducing the parasites for every 100 red blood cells (RBC) from 66 to 16 (75.75%) at the tolerable dosage level of 7.5 mg/kg body weight while Ciprofloxacin (an antibiotic known to have antimalarial effect) showed an insignificant antiplasmodial effect reducing the parasites for every 100 RBC from 65 to 64 (1.53%) at the tolerable dosage level of 10.7 mg/kg body weight. …”
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Retrospective Use of Whole-Genome Sequencing Expands the Multicountry Outbreak Cluster of Listeria monocytogenes ST1247 by Mihkel Mäesaar, Rafael Mamede, Terje Elias, Mati Roasto

“…It was concluded that the persistent nature of the multicountry outbreak-related L. monocytogenes strain VLTRLM2013 together with stress island, virulence, and antibiotic resistance genes could potentially be the determining factors for the extensive and prolonged outbreak affecting five European Union countries. …”
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Epidemiological Study of Hospital-Acquired Bacterial Conjunctivitis in a Level III Neonatal Unit by Catarina Dias, Márcia Gonçalves, Anabela João

“…Susceptibility patterns revealed bacterial resistances to several antibiotic classes. Gentamicin remains the adequate choice for empirical treatment of HAC in our NICU. …”
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Severe Wound Infection with Photobacterium damselae ssp. damselae and Vibrio harveyi, following a Laceration Injury in Marine Environment: A Case Report and Review of the Literatur... by Jörg Hundenborn, Steffi Thurig, Mechthild Kommerell, Heike Haag, Oliver Nolte

“…Management with daily wound dressing and antibiotic therapy (ofloxacin empirically, followed by doxycycline after availability of microbiology) led in the reported case to a favorable outcome, which seems to be, however, the exception based on a review of the available literature.…”
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Treated Follicular Lymphoma, Recurrent Invasive Pneumococcal Disease, Nonresponsiveness to Vaccination, and a Unique Pneumococcus by Clare Murphy, Donald Inverarity, Claire McGoldrick, Lindsay Mitchell, Pamela Paterson, Louise Thom, Giles Edwards

“…Patient management was influenced by host predisposition to pneumococcal infection, antibiotic intolerance, and poor response to polysaccharide pneumococcal vaccine. …”
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Evaluating the Factors Affecting COVID-19 Patients’ Mortality in Arak in 2020 by Hossein Mazaherpour, Masoumeh Soofian, Elham Farahani, Ahmad Saebbian, Mostafa Etebari, Sakineh Mazaherpour, Fatemeh Ashrafian, Amitis Ramezani

“…There was a significant relationship in terms of blood pressure, age, oxygen saturation, tachycardia, tachypnea, the interval between the onset of symptoms and hospitalization, diabetes mellitus, lung disease, cardiovascular disease, history of opium abuse, C-reactive protein, white blood cell, lymphocytes, hemoglobin, creatinine elevation, elevated liver enzyme, creatine phosphokinase, lactate dehydrogenase, ferritin, D-dimer, troponin, prothrombin time, international normalized ratio, intensive care unit admission days, arrhythmia, sepsis, acute respiratory distress syndrome, acute kidney injury (AKI), and the type of antiviral and antibiotic therapy between the two groups of patients. …”
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24-epibrassinolide regulates oxytetracycline-induced phytotoxicity and its detoxification mechanism by Suya Chen, Shanshan Zhou, Xuan Xuan, Lili Niu, Lu Zhao, Jingjie Guo, Dongmei Xu

“…Oxytetracycline (OTC), a crop-absorbable antibiotic, poses a health risk to humans through the food chain. …”
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<i>Salmonella</i> bacteria in farm animal feeds. Review by N. B. Shadrova, O. V. Pruntova, G. S. Skitovich, О. А. Akulich

“…A research into antimicrobial resistance of Salmonella isolates demonstrated resistance to such medicinalproducts as ceftriaxone, carbopenem and imipenem; and full genome sequencing showed at least one antibiotic resistance gene in 40% of Salmonella isolates detected at pig feed production plants.…”
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