Grave’s Disease with Severe Hepatic Dysfunction: A Diagnostic and Therapeutic Challenge by Ashok Krishna Bhuyan, Dipti Sarma, Uma Kaimal Saikia, Bipul Kumar Choudhury

“…Propylthiouracil was stopped and lithium along with steroid coverage was given to control her thyrotoxicosis which was later changed to methimazole. Broad spectrum antibiotic therapy was also started but without any response. …”
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Iatrogenic Proximal Urethro–Rectal Perforation During Foley Catheter Insertion by Claude Tayar, Ali Alameh, Rawan Abdallah, Jamil Boufarah, Yehya Tlaiss, Hadi Farhat

“…The inadvertent creation of a rectourethral fistula during the procedure led to an urgent multidisciplinary approach involving surgery and postoperative management, including fecal and urine diversion and antibiotic therapy. The case highlights the critical importance of meticulous technique and comprehensive preoperative patient assessment in minimizing the risk of such iatrogenic complications. …”
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Native Valve Endocarditis due to Veillonella Species: A Case Report and Review of the Literature by Lakshmi Saladi, Cosmina Zeana, Manisha Singh

“…The patient was discharged home after 10 days of inpatient antibiotic therapy and completed 4 weeks of IV ceftriaxone at home without any adverse events. …”
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Antimicrobial Effects of Egyptian Local Chicory, Cichorium endivia subsp. pumilum by Ahmed M. Amer

“…The discovery of novel and more efficient antimicrobial agents from natural sources like plants is one of the most important ways through which the growing threat of antibiotic-resistant pathogens can be overcome. Herein, we report the potential antimicrobial activity of Cichorium endivia L. subsp. pumilum. …”
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An Unusual Case of Cystic Fibrosis Associated Pneumocystis jiroveci Pneumonia in an Infant by Ravinder Kaur, Priyanka Katariya, Megh Singh Dhakad, Bhanu Mehra, Urmila Jhamb, A. P. Dubey

“…Bronchoalveolar lavage (BAL) fluid was collected and Pseudomonas aeruginosa was isolated on culture. Empirical antibiotic regimen comprising ceftriaxone and azithromycin was initiated that was switched to meropenem as per antimicrobial susceptibility report, but the patient did not improve. …”
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Mutant Prevention Concentrations of Imipenem and Meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii by E. Dahdouh, S. H. Shoucair, S. E. Salem, Z. Daoud

“…Detection of the mechanisms of resistance was performed using Antibiotic Susceptibility Testing, Double Disk Synergy, disk antagonism, addition of NaCl to the medium, addition of PBA or EDTA to Carbapenem disks, addition of PBA to Cefoxitin disks, and CCCP test for 10 Pseudomonas spp. and Acinetobacter baumannii strains. …”
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PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkholderia cenocepacia by Tinatini Tchatchiashvili, Helena Duering, Lisa Mueller-Boetticher, Christian Grune, Dagmar Fischer, Mathias W. Pletz, Oliwia Makarewicz

“…The results indicated that these organic NPs are effective vehicles for targeted antibiotic delivery in bacterial cells, explaining the observed increase in the efficacy of encapsulated tobramycin against biofilms. …”
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Spontaneously Regressing Neonatal Oral Aphthous Ulceration of the Palate by Sandara Wayangi Madurapperuma, Andra Hennadige Heshan Malinga Jayaweera, Ruwan Duminda Jayasinghe

“…Nasogastric feeding was commenced to avoid any irritation of the ulcer, and glycerine was applied on the ulcer. Antibiotic therapy was continued because of the intermittent mild fever. …”
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Disruption of biological membranes by hydrophobic molecules: a way to inhibit bacterial growth by Alejandra Gabriela Valdez-Lara, Ángela M. Jaramillo-Granada, Daniel Ortega-Zambrano, Eristeo García-Marquez, Jorge Alberto García-Fajardo, H. Mercado-Uribe, J. C. Ruiz-Suárez

“…With antibiotic resistance increasing in the global population every year, efforts to discover new strategies against microbial diseases are urgently needed. …”
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Targeting the Heart of Mycobacterium: Advances in Anti-Tubercular Agents Disrupting Cell Wall Biosynthesis by Ahmad Diab, Henry Dickerson, Othman Al Musaimi

“…<i>Mycobacterium tuberculosis</i> infections continue to pose a significant global health challenge, particularly due to the rise of multidrug-resistant strains, random mycobacterial mutations, and the complications associated with short-term antibiotic regimens. Currently, five approved drugs target cell wall biosynthesis in <i>Mycobacterium tuberculosis</i>. …”
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Meropenem Continuous Infusion in a Septic Patient with Periprosthetic Infection and End-Stage Renal Disease Undergoing Prolonged Intermittent Renal Replacement Therapy by Assiya Kadralinova, Maiya Konkayeva, Serik Dzhandayev, Aidos Konkayev

“…This case report highlights the use of continuous infusion of meropenem in a 42-year-old septic female patient with periprosthetic infection and end-stage renal disease receiving prolonged intermittent renal replacement therapy (PIRRT). Antibiotic infusion in patients receiving renal replacement therapy has its own peculiarities. …”
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Ovarian Fibroma as a Possible Cause of Fever of Unknown Origin by İkbal Kaygusuz, Ayla Eser, İlknur İnegöl Gümüş, İsmail Kırbaş, Kayıhan Akın, Hacer Haltas, Hasan Kafalı

“…Pus drainage was then planned but 3cc of serous material was drained from the adnexal mass with ultrasound-guide. Despite antibiotic therapy, her fever continued. She had a comprehensive work-up for FUO, including rheumatologic, infectious, and malignant etiologies. …”
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A two-strain TB model with multiplelatent stages by Azizeh Jabbari, Carlos Castillo-Chavez, Fereshteh Nazari, Baojun Song, Hossein Kheiri

“…A two-strain tuberculosis (TB) transmission model incorporating antibiotic-generated TB resistant strains and long and variable waiting periods within the latently infected class is introduced. …”
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Predicting phage-host interaction via hyperbolic Poincaré graph embedding and large-scale protein language technique by Jie Pan, Rui Wang, Wenjing Liu, Li Wang, Zhuhong You, Yuechao Li, Zhemeng Duan, Qinghua Huang, Jie Feng, Yanmei Sun, Shiwei Wang

“…Summary: Bacteriophages (phages) are increasingly viewed as a promising alternative for the treatment of antibiotic-resistant bacterial infections. However, the diversity of host ranges complicates the identification of target phages. …”
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Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine by Indrit Greca, Jihad Ben Gabr, Andras Perl, Stephanie Bryant, Dan Zaccarini

“…As a result, patients can be initiated on benign anti-inflammatory agents, avoiding invasive testing and unnecessary antibiotic exposure.…”
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Insights from a Genome-Wide Study of <i>Pantoea agglomerans</i> UADEC20: A Promising Strain for Phosphate Solubilization and Exopolysaccharides Production by Edith Elizondo-Reyna, Humberto Martínez-Montoya, Yahaira Tamayo-Ordoñez, María Antonia Cruz-Hernández, Mauricio Carrillo-Tripp, María Concepción Tamayo-Ordoñez, Gerardo de Jesús Sosa-Santillán, José Antonio Rodríguez-de la Garza, Mario Hernández-Guzmán, Virgilio Bocanegra-García, Erika Acosta-Cruz

“…The comprehensive set of genes supporting phosphate solubilization, EPS synthesis, and secretion, along with its low virulence and antibiotic resistance levels, justify further research for its potential biotechnological application and possible use as a plant growth-promoting agent in the field. …”
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Antimicrobial potential and mechanism of infant feces-derived Enterococcus faecalis in inhibiting Enterotoxigenic Escherichia coli by Xi Lu, Wei Sang, Lei Pan

“…Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in infants and travelers. However, antibiotic treatment is challenged by growing resistance. …”
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Relapsing Campylobacter jejuni Systemic Infections in a Child with X-Linked Agammaglobulinemia by Paola Ariganello, Giulia Angelino, Alessia Scarselli, Irene Salfa, Martina Della Corte, Arianna De Matteis, Patrizia D'Argenio, Susanna Livadiotti, Emma C. Manno, Cristina Russo, Andrea Finocchi, Caterina Cancrini

“…The humoral defect is considered to be crucial for this phenomenon, as well as the difficulties to eradicate the pathogen with an appropriate antibiotic therapy; drug resistance is raising in Campylobacter species, and the appropriate duration of treatment has not been established. …”
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Incontinentia Pigmenti Misdiagnosed as Neonatal Herpes Simplex Virus Infection by Fahimeh Abdollahimajd, Minoo Fallahi, Mohammad Kazemian, Yalda Nilipour, Mitra Radfar, Sedigheh Tahereh Tehranchi

“…She was admitted in the maternity hospital that was born and was treated by antibiotic and acyclovir for 11 days. Then, she readmitted for her distributed vesicular lesions. …”
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The effect of particle size on photocatalytic degradation of oxytetracycline by ZnO nanoparticles by Reza Torkamani, Bagher Aslibeiki, Masih Darbandi, Hamid Naghshara

“…The toxicity of oxytetracycline (OTC) antibiotic remains in the environment and threatens the life of living things. …”
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