Targeting Acinetobacter baumannii resistance-nodulation-division efflux pump transcriptional regulators to combat antimicrobial resistance by Ruwani L. Wimalasekara, Dawn White, Ayush Kumar

“…Though the role of efflux systems in antibiotic expulsion are well recognized, the regulatory mechanisms controlling their expression remain understudied. …”
Get full text

In Vitro Evaluation of Antimicrobial Efficacy of Extracts Obtained from Raw and Fermented Wild Macrofungus, Lenzites quercina by Olusola Clement Ogidi, Victor Olusegun Oyetayo, Bamidele Juliet Akinyele

“…In recent time, there is a major concern about antibiotic resistance displayed by some pathogenic microorganisms and this had involved a continuous search for natural antimicrobial products. …”
Get full text

Distribution and Characteristics of Bacteria Isolated from Cystic Fibrosis Patients with Pulmonary Exacerbation by Soroor Erfanimanesh, Mohammad Emaneini, Mohammad Reza Modaresi, Mohammad Mehdi Feizabadi, Shahnaz Halimi, Reza Beigverdi, Vajiheh Sadat Nikbin, Fereshteh Jabalameli

“…A cross-sectional study was conducted on the bacterial profile and antibiotic resistance pattern of 103 respiratory specimens from CF patients with signs of pulmonary exacerbation. …”
Get full text

Associations of time to the operating room on outcomes in odontogenic infection by Jeffrey N. James, Ryan Bloomquist, Kiara Brown, Stephen Looney, Dylan Walker, Tyler Day

“…Time of admission, time of surgical intervention, patient demographics, admission lab values, and space involvement were measured and compared to the primary outcome variables including complications of intubation attempts and type, ICU admission, length of hospitalization, number of changes in antibiotic therapy, and frequency of return to the operating room. …”
Get full text

A Phage‐Based Approach to Identify Antivirulence Inhibitors of Bacterial Type IV Pili by Tori M. Shimozono, Nancy J. Vogelaar, Megan T. O'Hara, Zhaomin Yang

“…ABSTRACT The increasing threat of antibiotic resistance underscores the urgent need for innovative strategies to combat infectious diseases, including the development of antivirulants. …”
Get full text

Impact of order set implementation on appropriate treatment of community-acquired pneumonia (CAP) by Han Pham, Michell J. Stein, Lacy J. Worden

“…Antibiotic order sets will be a useful tool for antimicrobial stewardship program expansion into other common community-acquired infections. …”
Get full text

Growth Characteristics of Sheep-Derived <i>Bacteroides fragilis</i> and Preliminary Research on Effects in Mice and Lambs by Cheng Cheng, Jinye Du, Jianping Tao, Darong Cheng

“…However, lamb diarrhea, a disease with high mortality rates, significantly hampers the industry’s growth. Traditional antibiotic treatments often disrupt the Intestinal microbiota, induce antibiotic resistance, and cause adverse side effects, highlighting the urgent need to develop alternative therapies. …”
Get full text

Economic Evaluation of Fidaxomicin for the Treatment of Clostridium Difficile Infection (C. difficile-associated diarrhoea) in Ireland by Anke van Engen, Montserrat Casamayor, Fidelma Loftus, Martin Coen, Andy Garnham, Maureen Watt, Larry Lacey

“…**Background:** Clostridium difficile is associated with 20–30% of cases of antibiotic-associated diarrhoea. The incidence of C. difficile infection (CDI) is higher in Ireland than in other countries in Europe, and it is associated with considerable morbidity. …”
Get full text

A Comprehensive Study of the Relationship between the Production of β-Lactamase Enzymes and Iron/Siderophore Uptake Regulatory Genes in Clinical Isolates of Acinetobacter baumannii... by Mahyar Porbaran, Hamed Tahmasebi, MohammadReza Arabestani

“…However, IUS’s role in antibiotic resistance and the production of β-lactamase enzymes of A. baumannii are unclear. …”
Get full text

Association of qnr Genes and OqxAB Efflux Pump in Fluoroquinolone-Resistant Klebsiella pneumoniae Strains by Fereshteh Amereh, Mohammad Reza Arabestani, Seyed Mostafa Hosseini, Leili Shokoohizadeh

“…Molecular typing of qnr-positive K. pneumoniae isolates was assessed by ERIC-PCR. Results. Antibiotic susceptibility testing showed high resistance (>80%) to fluoroquinolones. …”
Get full text

Infective endocarditis following transcatheter mitral valve-in-valve replacement: a clinical case report by Jing-Wei Zhang, Si-ying Liao, Jie Li, Feng-Juan Yao

“…Additionally, an appropriate perioperative antibiotic regimen is essential to prevent infection and improve prognosis.…”
Get full text

Antibacterial Activity and Mechanisms of Action of Inorganic Nanoparticles against Foodborne Bacterial Pathogens: A Systematic Review by Abayeneh Girma, Birhanu Abera, Bawoke Mekuye, Gedefaw Mebratie

“…Therefore, this study recommends the proper use of nontoxic inorganic nanoparticle products for food processing industries to ensure the quality and safety of food while minimizing antibiotic resistance among foodborne bacterial pathogens.…”
Get full text

Chlamydial Pneumonitis: A Creepy Neonatal Disease by Kam Lun Hon, Alexander K. C. Leung

“…The literature is searched to review if treatment with a systemic macrolide antibiotic is needed in an otherwise asymptomatic neonate with chlamydial pneumonitis.…”
Get full text

Temporary Mental Nerve Paresthesia Originating from Periapical Infection by Ozgur Genc Sen, Volkan Kaplan

“…Resolution of the paresthesia began two weeks after conventional root canal treatment associated with antibiotic therapy and was completed in eight weeks. …”
Get full text

Brucella Endocarditis as a Late Onset Complication of Brucellosis by Panagiotis Andriopoulos, Christos Antoniou, Panagiota Manolakou, Athanassios Vasilopoulos, George Assimakopoulos, Maria Tsironi

“…The patient underwent valve replacement and required prolonged antibiotic treatment because of rupture of the noncoronary leaflet and development of congestive heart failure. …”
Get full text

A Case of Prolonged Cholestatic Hepatitis Induced by Azithromycin in a Young Woman by Caterina Maggioli, Luca Santi, Giacomo Zaccherini, Vittoria Bevilacqua, Francesca Giunchi, Paolo Caraceni

“…Azithromycin, a semisynthetic macrolides, is frequently prescribed for the treatment of middle ear and upper respiratory tract infections, bronchitis, and community-acquired pneumonia. This antibiotic is usually well tolerated, and a rapid resolving cholestatic hepatitis has been described up to now only in six patients all, except one, over 65 years of age. …”
Get full text

Tracking des transferts des bactéries porteuses de résistances entre animal, homme et environnement by Meyer, Sylvain, Laval, Lucie, Pimenta, Mélanie, González-Flores, Yolanda, Gaschet, Margaux, Couvé-Deacon, Elodie, Barraud, Olivier, Dagot, Christophe, Ploy, Marie-Cécile

“…The fight against antibiotic resistance must incorporate the “One Health” concept to be effective. …”
Get full text

Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…Pan-genome analysis with Roary identified core and accessory genes. Antibiotic resistance genes, virulence factors, and toxins were detected using the CARD and VFDB databases, and the ABRicate software. …”
Get full text

Efficient degradation of neomycin by Bacillus velezensis and Cupriavidus basilensis isolated from mangrove soil and pharmaceutical wastewater by Qian Yang, Wenzhuan Huang, Xue Yan, Qiang Ding, Jiaxin Liu, Bo Cheng, Tao Duan

“…Neomycin, an aminoglycoside antibiotic, is widely utilized for veterinary medicine in disease prevention. …”
Get full text

Colistin broth disk elution for the detection of Colistin resistance among Carbapenem-resistant Klebsiella pneumoniae by Phu Thien Truong, Ngoc Bich Tran, Hoang Huy Pham, Van Thi Hue Tran, Hoang Thanh Phan, Binh Thai Pham, Lam Thi Ngoc Tran, Truc Thi Thanh Nguyen, Mai Le Phuong, Dat Quoc Ngo

“…The escalating resistance to colistin, a crucial last-resort antibiotic, underscores the need for precise and dependable antimicrobial susceptibility testing (AST) methods. …”
Get full text