Vic9 mycobacteriophage: the first subcluster B2 phage isolated in Russia by Marina Zaychikova, Maja Malakhova, Dmitry Bespiatykh, Maria Kornienko, Ksenia Klimina, Aleksandra Strokach, Roman Gorodnichev, Arina German, Mikhail Fursov, Dmitry Bagrov, Dmitry Bagrov, Anna Vnukova, Alexandra Gracheva, Anastasia Kazyulina, Margarita Shleeva, Egor Shitikov

“…This collection also holds significant potential for therapeutic applications, particularly as an alternative to antibiotics in combating drug-resistant bacterial strains. …”
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The role of artificial intelligence and machine learning in predicting and combating antimicrobial resistance by Hazrat Bilal, Muhammad Nadeem Khan, Sabir Khan, Muhammad Shafiq, Wenjie Fang, Rahat Ullah Khan, Mujeeb Ur Rahman, Xiaohui Li, Qiao-Li Lv, Bin Xu

“…In addition, AI-based clinical decision support systems in real-time guide healthcare professionals to improve prescribing of antibiotics. The review also outlines how can AI improve AMR surveillance, analyze resistance trends, and enable early outbreak identification. …”
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Evaluation of Tumour Necrosis Factor Alpha, Interleukin-2 Soluble Receptor, Nitric Oxide Metabolites, and Lipids as Inflammatory Markers in Type 2 Diabetes Mellitus

“…To restrict the influence of variables that could interfere in the interpretation of data, subjects with obesity and/or acute or chronic inflammatory disease, haemoglobinopathies, recent use of antibiotics, antiinflammatory drugs, and trauma were excluded. …”
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Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) trial: study protocol for a multicentre, double-blinded, placebo-controlled, phase IIa trial by Julian R Marchesi, Emma Nicholson, Benjamin H Mullish, Renuka Palanicawandar, Graham Wheeler, Francesca Kinsella, Andrew J Innes, Lauren A Roberts, Shian Anim-Burton, Lee Webber, Nicholas A Johnson, Rohma Ghani, Pakhshan Farshi, Anjum B Khan, Panagiotis Kottaridis, Pramila Krishnamurthy, Frances Davies, Jiří Pavlů

“…Most patients undergoing HCT for a haematological malignancy have previously received intensive chemotherapy, resulting in prolonged neutropenic episodes requiring broad-spectrum antibiotics; use of these has been linked to reduced microbiome diversity. …”
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Perbandingan Levofloxacin dengan Ciprofloxacin Peroral dalam Menurunkan Leukosituria Sebagai Profilaksis Isk pada Kateterisasi di RSUP. Dr. M. Djamil Padang by Marwazi Sofyan, Alvarino ., Erkadius3 .

“…It is therefore a research on this efficacy between those antibiotics in lowering the incidence of leukocyturia as the measure to prevent UTI in patients with Foley catheter. …”
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Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing by Qianwen Ge, Qianwen Ge, Liangxing Fang, Liangxing Fang, Liangxing Fang, Yang Yu, Yang Yu, Yang Yu, Ruanyang Sun, Ruanyang Sun, Xiaoping Liao, Xiaoping Liao, Xiaoping Liao, Peng Zhang, Peng Zhang, Peng Zhang

“…Sequence types (STs) were identified by multilocus sequence typing (MLST).ResultsPhenotypic analysis showed that most isolates were susceptible to the tested antibiotics; resistance was most common against tetracycline (27%) and enrofloxacin (20%). …”
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A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas by Kun Xiao, Yan Cao, Zhihai Han, Yuxiang Zhang, Laurence Don Wai Luu, Liang Chen, Peng Yan, Wei Chen, Jiaxing Wang, Ying Liang, Xin Shi, Xiuli Wang, Fan Wang, Ye Hu, Zhengjun Wen, Yong Chen, Yuwei Yang, Haotian Yu, Lixin Xie, Yi Wang

“…Current therapeutic strategies beyond antibiotics and adjuvant therapies are limited, highlighting the need for a deeper understanding of the disease pathogenesis. …”
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Universal antibacterial and anti-inflammatory treatment using chitosan-prussian blue nanozyme by Jian Wang, Jiayi Wang, Huayuan Zhou, Rui Ma, Zhou Fang, Jiawei Zhu, Zhejie Chen, Xinfeng Dai, Dali Wei, Jiabei Li, Yiting Jiang, Qian Xia, Xueliang Liu, Yu Yang

“…Bacterial infections are a growing global public health problem, exacerbated by the widespread and often inappropriate use of antibiotics, leading to the emergence of non-antibiotic pathogens. …”
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Genomic characteristics of a Streptococcus suis of ST353 resulting in severe endophthalmitis with bilateral deafness by Liang Shen, Yanfei Tong, Shichao Li, Yuda Chen, Ruhan A, Zhen Li, Wenling Wang, Lijuan Yin, Jiuming Zou, Ziyong Sun, Changcheng Wu, Wenjie Tan, Haijuan Wang

“…Drug susceptibility testing was conducted to determine the effectiveness of antibiotics. Whole-genome sequencing was used to identify the strain’s sequence type and serotype as well as the presence of pathogenicity islands (PAIs). …”
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Phenotypic and Complete Reference Whole Genome Sequence Analyses of Two <i>Paenibacillus</i> spp. Isolates from a Gray Wolf (<i>Canis lupus</i>) Gastrointestinal Tract by Jessika L. Bryant, Jennifer McCabe, C. Cristoph Klews, MiCayla Johnson, Ariel N. Atchley, Thomas W. Cousins, Maya Barnard-Davidson, Kristina M. Smith, Mark R. Ackermann, Michael Netherland, Nur A. Hasan, Peter A. Jordan, Evan S. Forsythe, Patrick N. Ball, Bruce S. Seal

“…The bacteria were typed as Gram-variable, and both were catalase/oxidase positive as well as sensitive to commonly used antibiotics. The bacteria digested complex carbohydrates and lipids by standard assays. …”
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The role of airway management group in tracheotomy decannulation in patients with severe acquired brain injury (气道管理小组在重度获得性脑损伤患者拔除气切套管中的作用)... by LIU Yuewei (刘月伟), WANG Yuan (王远), ZHANG Jimin (张继敏), SONG Lu (宋璐)

“…The incidence of aspiration following extubation, aspiration pneumonia and rate of using antibiotics in the study group were lower than those in the control group (P＜0. 05). …”
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Antimicrobial Stewardship in the Pediatric Emergency Department: An Observational Pre-Post Study by Erika Silvestro, Ilaria Mussinatto, Antonia Versace, Marco Denina, Giulia Pruccoli, Raffaella Marino, Giulia Mazzetti, Lorenzo Scaglione, Federico Vigna, Alessandra Macciotta, Silvia Garazzino, Claudia Bondone

“…We recorded all systemic antibiotic prescriptions for children attending our pediatric ED from January to March and from July to September 2020. …”
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Exploration of the feasibility of clinical application of phage treatment for multidrug-resistant Serratia marcescens-induced pulmonary infection by Xiangke Duan, Wenfeng Liu, Yanyu Xiao, Man Rao, Liyin Ji, Xiaofu Wan, Shuhong Han, Zixun Lin, Haichen Liu, Peifen Chen, Kun Qiao, Mingbin Zheng, Jiayin Shen, Yang Zhou, Tetsuya Asakawa, Minfeng Xiao, Hongzhou Lu

“…It did not induce or deteriorate drug resistance of the involved antibiotics. Importantly, no adverse events were reported during the treatment or follow-up periods. …”
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Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan... by Justine BN, Mushi MF, Silago V, Igembe Z, Muyombe J, Kishengena PP, Michael Jnr NS, Maganga MG, Massenga A, Tegete F, Massaga FA, Seni J

“…Revisiting SSTIs treatment guidelines at BMC and inclusion of SSTIs in the on-going AMR surveillance in Tanzania are recommended.Plain Language Summary: Tanzania National Action Plan on combating resistant bugs is exclusively focused on urinary tract infections and blood stream infections despite enormous impact conferred by skin and soft tissue infections.Bugs which are resistant to commonly used antibiotics were found more among patients admitted in the hospital in contrast to those attending outpatient clinics.This study highlights a pressing need to develop treatment guidelines based on generated local research-evidence to foster favorable patients’ outcomes.Keywords: skin and soft tissue infections, antimicrobial resistance, surveillance, Tanzania…”
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Targeting KRAS G12C and G12S mutations in lung cancer: In silico drug repurposing and antiproliferative assessment on A549 cells by Mansour S. Alturki, Nada Tawfeeq, Amal Alissa, Zahra Ahbail, Mohamed S. Gomaa, Abdulaziz H. Al Khzem, Thankhoe A. Rants'o, Mohammad J. Akbar, Waleed S. Alharbi, Bayan Y. Alshehri, Amjad N. Alotaibi, Fahad A. Almughem, Abdullah A. Alshehri

“…The computational studies involved virtual screening, induced fit, and covalent docking, and molecular dynamics simulations, and identified five promising candidates, the antibiotics; capreomycin, cefadroxil, and Cefdinir, the antifungal; natamycin, and the anti-inflammatory, cortisone. …”
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

“…Typhimurium, ST) is a food-borne pathogen that can be transmitted from animals to humans and causes symptoms such as diarrhea, fever, and vomiting. While antibiotics are commonly used to treat clinical infections, the increase in drug resistance has limited their effectiveness. …”
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Evaluating the health risk of probiotic supplements from the perspective of antimicrobial resistance by Qiwen Tian, Hailv Ye, Xuan Zhou, Junyi Wang, Lifang Zhang, Wenxuan Sun, Chenxin Duan, Minyu Fan, Wei Zhou, Chuyun Bi, Qiong Ye, Aloysius Wong

“…Streptomycin-adapted probiotics also gained resistance to other antibiotics more effectively than non-adapted ones. …”
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Efficacy and safety of anemoside B4 in canine pneumonia treatment: a prospective, randomized controlled trial by Jinzhao Ji, Jinzhao Ji, Xiaoqing Ding, Xiaoqing Ding, Chuanli Liu, Chuanli Liu, Lingling Dai, Lingling Dai, Junting Yu, Junting Yu, Linghao Li, Linghao Li, Shaobing Wan, Shaobing Wan, Yangyang Song, Junqing Zhao, Zhetong Su, Kun Jia, Kun Jia, Shoujun Li, Shoujun Li

“…Current treatment strategies primarily rely on antibiotics and corticosteroids; however, the emergence of antibiotic resistance and potential side effects from prolonged corticosteroid use limit the effectiveness of these therapies in clinical practice. …”
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Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

“…Nineteen articles on human health dealt with prescribing and/or use of antimicrobials, five on self-medication, two on non-compliance of dosage, and 10 on the sensitivity and resistance patterns of antibiotics. Four papers focused on the use of antimicrobials in food animals and seven on environmental contamination. …”
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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…BackgroundAmid growing concern about antimicrobial resistance due to the irrational use of antibiotics in treating common poultry diseases, particularly Salmonella which is a foodborne pathogen in humans. …”
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