Impact of meropenem exposure on fluoroquinolone and carbapenem resistance in Pseudomonas aeruginosa infection in inpatients in a Japanese university hospital: Insights into oprD mu... by Tadanori Yamochi, Kazuhisa Ugajin, Rintaro On, Sho Inoue, Hiromi Ikeda, Toshiko Yamochi, Masafumi Takimoto, Issei Tokimatsu

“…The minimal inhibitory concentrations of clinically relevant antibiotics were determined. Quantitative PCR was performed to analyze oprD, mexB, mexC, mexE, and mexY expression. …”
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Does macrolide use confer risk of out-of-hospital cardiac arrest compared with penicillin V? A Danish national case-crossover and case–time–control study by Lars Køber, Freddy Lippert, Charlotte Andersson, Peter E Weeke, Gunnar H Gislason, Frederik Boetius Hertz, Aksel Jensen, Jenny D Knudsen, Magnus Arpi, Christian Torp–Pedersen

“…From nationwide registries, we identified all OHCAs in Denmark from 2001 to 2010 and use of antibiotics.Ethics The present study was approved by the Danish Data Protection Agency (Danish Data Protection Agency (ref.no. 2007-58-0015, local ref.no. …”
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Prediction model for unfavorable treatment outcome for complicated sever acute malnutrition (SAM) in under five children admitted in hospitals at Amhara Region by Almaw Genet Yeshiwas, Zelalem Alamrew Anteneh, Tilahun Degu Tsega, Ahmed Fentaw Ahmed, Chalachew Yenew

“…Emphasis should be placed on timely interventions, including the administration of folic acid and Vitamin A supplementation, as well as intravenous antibiotics. Implementing a comprehensive care plan that addresses these factors will significantly improve treatment outcomes and enhance recovery in this vulnerable population.…”
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Clinical Features of iatrogenic Pharyngo-esophageal perforation in very low birth weight infants by Shu Eguchi, Yoshiya Hisaeda, Toshiko Ukawa, Mayu Koto, Miku Hosokawa, Chisa Tsurisawa, Tomohiro Takeda, Shusuke Amagata, Atsushi Nakao

“…All patients were treated conservatively with antibiotics and survived. Conclusions: When inserting a gastric tube for premature infants, it is critical to remember that these infants are at risk of IPEP. …”
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Candida Bloodstream Infection: Changing Pattern of Occurrence and Antifungal Susceptibility over 10 Years in a Tertiary Care Saudi Hospital by Nawaf Alkharashi, Sameera Aljohani, Laila Layqah, Emad Masuadi, Waleed Baharoon, Hamdan AL-Jahdali, Salim Baharoon

“…Use of broad spectrum antibiotics (82%), prior ICU admission (60%) and use of central venous catheters (58%) were the most prevalent predisposing factors of candidemia. …”
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The β-Lactamase Gene Profile and a Plasmid-Carrying Multiple Heavy Metal Resistance Genes of Enterobacter cloacae by Chongyang Wu, Chaoqin Lin, Xinyi Zhu, Hongmao Liu, Wangxiao Zhou, Junwan Lu, Licheng Zhu, Qiyu Bao, Cong Cheng, Yunliang Hu

“…In this work, by high-throughput sequencing, antibiotic resistance genes, including class A (blaCTX-M, blaZ, blaTEM, blaVEB, blaKLUC, and blaSFO), class C (blaSHV, blaDHA, blaMIR, blaAZECL-29, and blaACT), and class D (blaOXA) β-lactamase genes, were identified among the pooled genomic DNA from 212 clinical Enterobacter cloacae isolates. …”
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Efficacy of Adjunctive Antiseptic Lavage Solution in Managing Acute Hip/Knee Prosthetic Joint Infection: A Comparative Study in a Tertiary Revision Center by Jonathan Quinn, FRACS, Bernard H. van Duren, DPhil, FRCS, Reshid Berber, PhD, FRCS, Mark Higgins, FRCS, Hosam E. Matar, FRCS, Andrew R. Manktelow, FRCS, Benjamin V. Bloch, FRCS

“…Background: Debridement, antibiotics and implant retention (DAIR) procedure is well-established as a management option for acute periprosthetic joint infection (PJI). …”
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Can Gut Microbiota Analysis Reveal <i>Clostridioides difficile</i> Infection? Evidence from an Italian Cohort at Disease Onset by Roberto Rosato, Gianluca Quaranta, Giulia Santarelli, Giovanni Fancello, Delia Mercedes Bianco, Francesca Romana Monzo, Stefano Bibbò, Giovanni Cammarota, Maurizio Sanguinetti, Luca Masucci, Flavio De Maio

“…<i>Clostridioides difficile</i> infection (CDI) is predominantly associated with the overuse of antibiotics, resulting in a significant alteration in the gut’s microbial balance. …”
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Antibacterial Effect of Luma apiculata (DC.) Burret Extracts in Clinically Important Bacteria by Tiare Araya-Contreras, Rhonda Veas, Carlos A. Escobar, Pamela Machuca, Mauricio Bittner

“…Moreover, the resistance to antibiotics by these bacteria makes it necessary to find new treatments to fight them. …”
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Perforated Carcinoma in the Gastric Remnant: A Case of Conservative Treatment Prior to Successful Curative R0 Resection by Ken Yuu, Hiroshi Kawashima, Sho Toyoda, Satoshi Okumura, Kansuke Yamamoto, Naoto Mizumura, Aya Ito, Hiromitsu Maehira, Atsuo Imagawa, Masao Ogawa, Masayasu Kawasaki, Masao Kameyama

“…Conservative medical management was selected, including nasogastric tube insertion, antibiotics, and proton pump inhibitors, because his peritonitis was limited to his epigastrium and his general condition was stable. …”
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Sensitivitas Bakteri Penyebab Sepsis Neonatorum terhadap Meropenem di Neonatal Intensive Care Unit dan Perinatologi RSUP DR M Djamil Padang Padang Tahun 2012 by Susan Insani Putri, Aziz Djamal, Rahmatini .

“…Meropenem is a third line antibiotics with ultra-broad spectrum. It is widely used in many installations at RSUP DR M. …”
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Can the Risk Factors Predicting Surgical Treatment be Determined in Patients with Tubo-Ovarian Abscess? by Tayfun Vural, Burak Bayraktar, Suna Yildirim Karaca, Emir Gurbuz, Mehmet Ozeren, Cuneyt Eftal Taner

“…Sixty-nine patients with tubo-ovarian abscess were treated with parenteral antibiotics. Some of them required surgery because antibiotic treatment was not successful. …”
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Retrospective cross-sectional study on bronchiectasis in adult Aboriginal Australians: disease characteristics and comparison with ethnically diverse global bronchiectasis registry... by Timothy Howarth, Subash Heraganahally, Claire Gibbs, Lata Jayaram, Asanga Abeyaratne, Shiidheshwar J Ravichandran, Davaadorj Erdenebayar, Winnie Chen, Hubertus Jersmann

“…Chest CT demonstrated multilobar and lower lobes involvement in 73% and inhaled pharmacotherapy use was recorded in up to 62% and long-term antibiotics in 5%.Conclusion The overall bronchiectasis disease burden is higher in Aboriginal Australian adults in comparison with global ethnically diverse non-Indigenous populations. …”
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Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…Conclusion Our meta-analysis suggests that PEDD is a potentially effective and safe intervention for SI. Optimizing antibiotic discontinuation and postoperative care strategies may contribute to reducing reoperation rate. …”
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Multiple viral infections and antimicrobial use in hospitalized children with respiratory illness during pandemic and early post-pandemic era, Taiwan by Chyi-Liang Chen, Yi-Ching Chen, Hsuan-Ling Hsiao, Yi-Jung Chang, Hsin-Chieh Li, Merve Arslan Aydin, Cheng-Hsun Chiu

“…Pediatric physicians continued to use antibiotics for febrile symptoms in hospitalized children with respiratory illness, even when viral pathogens were identified.…”
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A Multifunctional Cobalt‐Containing Implant for Treating Biofilm Infections and Promoting Osteointegration in Infected Bone Defects Through Macrophage‐Mediated Immunomodulation by Nongyang Yan, Hao Zhou, Penghe Jin, Tengfei Li, Qi Liu, Hao Ning, Zhixin Ma, Linfei Feng, Tao Jin, Youwen Deng, Zhengwei Wu

“…Abstract Treating bone infections and ensuring bone recovery is one of the major global problems facing modern orthopedics. Prolonged antibiotic use may increase the risk of antimicrobial resistance, and inflammation caused by biofilms can obstruct tissue healing, making bone infection treatment even more challenging. …”
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Phage vB_KlebPS_265 Active Against Resistant/MDR and Hypermucoid K2 Strains of <i>Klebsiella pneumoniae</i> by Vyacheslav I. Yakubovskij, Vera V. Morozova, Yuliya N. Kozlova, Artem Yu. Tikunov, Valeria A. Fedorets, Elena V. Zhirakovskaya, Igor V. Babkin, Alevtina V. Bardasheva, Nina V. Tikunova

“…<i>Klebsiella pneumoniae</i> is an important opportunistic pathogen often resistant to antibiotics. Specific phages can be useful in eliminating infection caused by <i>K. pneumoniae</i>. …”
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Lethal necrotizing granulomatous vasculitis after bariatric surgery and bilateral mammaplasty by O. V. Blagova, D. Kh. Aynetdinova, A. V. Nedostup, N. A. Novikova, Ye. A. Kogan, Yu. V. Lerner, L. V. Kozlovskaya, V. V. Rameyev, N. A. Mukhin

“…Patient underwent multiple investigations aimed for ruling out infectious causes of the disease that yielded negative result, repetitive courses of antibiotics provided transient positive effect at onset of disease. …”
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Genomic Diversity and Potential Transmission and Persistence of Salmonella in the Cambodian Vegetable Supply Chain by Abimel Salazar, Navin Sreng, Chanthol Peng, Yehzi Fu, Erin M. Nawrocki, Taejung Chung, Jessie Vipham, Edward G. Dudley, Jasna Kovac

“…Lastly, among 78 analyzed isolates, 14 carried antimicrobial resistance genes and seven out of these 14 carried genes with predicted resistance to more than three classes of antibiotics. Overall, highly similar isolates of Salmonella were identified over time and at different supply chain stages, suggesting possible persistence and transmission of Salmonella within and between supply chain stages.…”
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Synergistic antimicrobial activity of essential oils mixture of Moringa oleifera, Cinnamomum verum and Nigella sativa against Staphylococcus aureus using L-optimal mixture design by Samah H. Abu-Hussien, Antony R. Nasry, Ziad Samy, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa ElNoby

“…The results underscore how combining essential oils could help address the issue of antibiotic resistance in S. aureus.…”
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