Pooling the complex survey data across the 64 lower and middle-income countries: A study on antibiotic usage in under-five children by Md Fakrul Islam, Prosenjit Basak Arka, Mahfuzer Rohman, Md Sabbir Hossain, Md Rashed Babu, Hasin Anupama Azhari, Md Jamal Uddin

“…This excessive use could result in higher healthcare costs, and antibiotic resistance is an alarming trend in developing countries. …”
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Enhancing antibacterial photodynamic therapy with NIR‐activated gold nanoclusters: Atomic‐precision size effect on reducing bacterial biofilm formation and virulence by Chengyu Liu, Tenghui Tian, Yujia Shi, Meiqi Li, Le Hong, Jing Zhou, Jia Liu, Yuan Zhong, Xue Wang, Zhenyu Wang, Xue Bai, Lin Wang, Chunyan Li, Zhennan Wu

“…Abstract Persistent biofilm infections pose a critical health threat with their relentless presence and amplified antibiotic resistance. Traditional antibacterial photodynamic therapy can inhibit bacteria extracellularly but struggles to control biofilm formation and virulence. …”
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Overcoming beta-lactam resistance in Pseudomonas aeruginosa by targeting metallo-beta-lactamase VIM-1: a one-microsecond molecular dynamics simulation study by Mohammed Salleh M. Ardawi, Samar A. Badreddine, Muhammad Yasir, Muhammad Yasir, Aiah M. Khateb, Aiah M. Khateb, Safaa A. Turkistani, Ahmed Afandi, Samah O. Noor, Adhari Alselmi, Adhari Alselmi, Vivek Dhar Dwivedi, Vivek Dhar Dwivedi, Esam I. Azhar, Esam I. Azhar

“…The findings highlighted that these four potent MBL-VIM-1 inhibitors show superior binding affinity and stability, suggesting their potential to combat antibiotic resistance in P. aeruginosa. The identified compounds offer a promising avenue for developing novel therapeutics to restore the efficacy of beta-lactam antibiotics against resistant bacterial strains. …”
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Antimicrobial Resistance Genes in Clinical <i>Escherichia coli</i> Strains from Livestock and Poultry in Shandong Province, China During 2015–2020 by Miaoli Wang, Shaopeng Wu, Yao Wang, Feng Chen, Zhangqi Shen, Zouran Lan

“…There have been a lot of studies on the antibiotic resistance of <i>E. coli</i> in livestock and poultry, but few of them have focused on clinical pathogens. …”
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Early onset neonatal bloodstream infections in South African hospitals by Genevieve Theron, Adrie Bekker, Larisse Bolton, Andrew Whitelaw, Arnoldus Engelbrecht, Louisa Erasmus, Aaqilah Fataar, Chandre Geldenhuys, Marlize Kunneke, Dave Le Roux, Natasha O’Connell, Kessendri Reddy, Natasha Rhoda, Lloyd Tooke, Mark Wates, Thandi Wessels, Angela Dramowski

“…Abstract Background Neonatal sepsis is a leading cause of death in low- and middle- income countries (LMIC). Increasing antibiotic resistance in early onset (< 72 h of life) bloodstream infection (EO-BSI) pathogens in LMIC has reduced the effectiveness of the recommended empiric antibiotic regimen (ampicillin plus gentamicin). …”
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Microbial community structure and functional traits involved in the adaptation of culturable bacteria within the gut of amphipods from the deepest ocean by Yukun Cui, Yu Xiao, Zhuo Wang, Paiyao Ji, Changhao Zhang, Yongqi Li, Jiasong Fang, Xi Yu

“…In addition, the presence of antibacterial compounds and antibiotic resistance genes, as well as the ability to form a biofilm, facilitated the successful colonization of P. pentosaceus XY62 in the gut environment.IMPORTANCEAmphipods are widely distributed in the Hadal trenches, and the study of their gut microbes has garnered considerable scientific interest. …”
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Targeted Antibiotic Prophylaxis for Lung Transplantation in Cystic Fibrosis Patients Colonised with Pseudomonas aeruginosa Using Multiple Combination Bactericidal Testing by Helmy Haja Mydin, Paul A. Corris, Audrey Nicholson, John D. Perry, Gerard Meachery, Emma C. L. Marrs, Steven Peart, Christine Fagan, James L. Lordan, Andrew J. Fisher, Frances K. Gould

“…Microorganisms cultured were mapped against antibiotic resistance, method of sensitivity testing, and antibiotics administered peritransplant. 129 patients were identified (mean age 28, male : female, 63 : 66). …”
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Understanding phage BX-1 resistance in Vibrio alginolyticus AP-1 and the role of quorum-sensing regulation by Xiaoyu Li, Xin Liu, Tianyi Ma, Haochen Su, Bingrui Sui, Lili Wang, Bilal Murtaza, Yongping Xu, Na Li, Demeng Tan

“…Collectively, our findings reveal the intricate dynamics of phage-host interactions, adding a new layer of complexity to our understanding of phage receptor regulations.IMPORTANCEPhage therapy has garnered significant attention as a promising solution to antibiotic resistance in aquaculture. However, its application is hindered by a limited understanding of the genotypic and phenotypic dynamics governing phage-host interactions. …”
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Genomic epidemiology and antimicrobial resistance of Morganella clinical isolates between 2016 and 2023 by Wentao Zhu, Qian Liu, Jinlv Liu, Jinlv Liu, Yaqi Wang, Yaqi Wang, Hong Shen, Ming Wei, Ji Pu, Li Gu, Jing Yang, Jing Yang, Jing Yang

“…The highest rates of antibiotic resistance were observed with SAM (68.3%), followed by CIP (39.9%), and SXT (37.2%). …”
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Comparison of Nasal Colonization of Methicillin-Resistant Staphylococcus aureus in HIV-Infected and Non-HIV Patients Attending the National Public Health Laboratory of Central Nepa... by Kalash Neupane, Binod Rayamajhee, Jyoti Acharya, Nisha Rijal, Dipendra Shrestha, Binod G C, Mahesh Raj Pant, Pradeep Kumar Shah

“…Intrinsically developed antibiotic resistance has sharply increased the burden of MRSA which is often associated with morbidity and mortality of the patients. …”
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Clinical Characteristics and Optimization of Empirical Antimicrobial Therapy for Febrile Neutropenia in Patients With Hematologic Malignancies by Cui Y, Liu X, Feng S

“…Empirical broad-spectrum antibiotics can be safely discontinued in FUO patients after 48 hours of clinical stability and apyrexia.Conclusion: Proper selection of empirical antibiotics and determining optimal treatment duration are essential for reducing antibiotic resistance and improving outcomes in HM patients with FN. …”
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Detection of Integrase Gene in E. coli Isolated from Pigs at Different Stages of Production System by Eulalia de la Torre, Rocío Colello, Nora Lía Padola, Analía Etcheverría, Edgardo Rodríguez, Fabián Amanto, María Ofelia Tapia, Alejandro Luis Soraci

“…Integrons are one of the genetic elements involved in the acquisition of antibiotic resistance. The aim of the present research is to investigate the presence of integrons in commensal Escherichia coli (E. coli) strains, isolated from pigs at different stages of production system and from the environment in an Argentinian farm. …”
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Exogenous cystine increases susceptibility of drug-resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels by Junyuan Du, Junyuan Du, Zhiyi Wu, Zhiyi Wu, Chunyang Zhu, Chunyang Zhu, Heng Yang, Heng Yang, Feike Zhao, Feike Zhao, Binghu Fang, Binghu Fang

“…Numerous studies have demonstrated that the addition of adjuvants can counteract bacterial antibiotic resistance.MethodCystine treatment was verified in vitro to promote the lethal effect of gentamicin on Salmonella using in vitro bactericidal counting methods. …”
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Phenotypic and genotypic characterization of clinical carbapenem-resistant Acinetobacter species harboring the metallo-beta-lactamases IMP-8 or NDM-1 in China by Qingye Xu, Xinli Mu, Jintao He, Haiyang Liu, Xiaochen Liu, Yanfei Wang, Xiaoting Hua, Yunsong Yu

“…This retrospective analysis serves as a form of “bacterial archaeology,” providing evidence of the evolutionary changes in genetic elements conferring antibiotic resistance.…”
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Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming by Maciej Nowak, Zbigniew Paluszak, Natalia Wiktorczyk-Kapischke, Katarzyna Grudlewska-Buda, Anna Budzyńska, Joanna Skonieczna-Kurpiel, Ewa Wałecka-Zacharska, Monika Huse-Kutowska, Krzysztof Skowron

“…In addition, the results presented can help to introduce standards regulating the safety of organic farming, taking into account the occurrence of antibiotic-resistant or highly invasive strains, thus maintaining food safety.…”
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The Importance of Antimicrobial Strategies Associated with Clinical Cure and Increased Microbiological Eradication in Patients with Complicated Urinary Tract Infections and High Ri... by José Medina Polo, Jose Luis Alfonso Sánchez, Jorge Arca-Suárez, Ángel Estella, Pablo González, Martí Blasco, Alicia Gil, Leonor del Mar Periañez Párraga, Francisco Javier Membrillo de Novales

“…Antimicrobial therapeutic strategies associated with increased microbiological eradication in cUTI patients with a high risk of relapse are crucial to prevent relapses and development of antibiotic resistance.…”
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Safety assessment of a novel marine multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 according to phenotype and whole genome-sequencing analysis by Xueyan Mo, Mengcheng Zhou, Yanmei Li, Lili Yu, Huashang Bai, Peihong Shen, Xing Zhou, Haojun Zhu, Huijie Sun, Ru Bu, Chengjian Jiang

“…Results showed that the genes and phenotypic expression of related virulence, antibiotic resistance and retroelement were rarely found. …”
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Prevalence of common diarrheagenic enterobacteriaceae in Iran (2000–2023): a systematic review and meta-analysis by Mozhgan Derakhshan-Sefidi, Fereshteh Eidy, Somayyeh Nadi-Ravandi, Sareh Bagheri-Josheghani, Maryam Mirfakhraei

“…Further research should investigate the factors contributing to the prevalence of diarrheagenic Enterobacteriaceae, including genetic diversity of diarrheagenic Enterobacteriaceae isolates, molecular mechanisms underlying the virulence of these pathogens, or antibiotic resistance patterns.…”
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Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system by Sarah Hollingshead, Gareth McVicker, Maria R. Nielsen, YuGeng Zhang, Giulia Pilla, Rebekah A. Jones, Jonathan C. Thomas, Sarah E. H. Johansen, Rachel M. Exley, Ditlev E. Brodersen, Christoph M. Tang

“…TA systems have also been implicated in bacterial persistence and antibiotic tolerance, which can be precursors of antibiotic resistance. Here, we identified a clinical isolate of Shigella sonnei (CS14) with a remarkably stable pINV virulence plasmid; pINV is usually frequently lost from S. sonnei, but plasmid loss was not detected from CS14. …”
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Emerging Resistance and Virulence Patterns in <i>Salmonella enterica</i>: Insights into Silver Nanoparticles as an Antimicrobial Strategy by Irina Gheorghe-Barbu, Ilda Czobor Barbu, Rareș-Ionuț Dragomir, Ioana Cristina Marinaș, Miruna Silvia Stan, Radu Pericleanu, Andreea Ștefania Dumbravă, Liviu-Iulian Rotaru, Simona Paraschiv, Leontina Mirela Bănică, Ionuț Pecete, Dan Oțelea, Violeta Corina Cristea, Mircea Ioan Popa, Marilena Monica Țânțu, Marius Surleac

“…Background/Objectives: This study aims to characterize antibiotic resistance (AR) and virulence markers in <i>Salmonella</i> spp. isolated from Romanian outpatients’ stool samples. …”
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