Antimicrobial Susceptibility Patterns of Shigella Species among Children under Five Years of Age with Diarrhea in Selected Health Centers, Addis Ababa, Ethiopia by Basha Ayele, Zeleke Mekonnen, Tesfaye Sisay Tessema, Etsehiwot Adamu, Estifanos Tsige, Getenet Beyene

“…The high levels of antibiotic resistance observed among the commonly prescribed antibiotics are alarming. …”
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CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1 by Kamilla Wiull, Lisa K. Haugen, Vincent G. H. Eijsink, Geir Mathiesen

“…An obstacle in developing bacterial delivery vehicles is generating a production strain that lacks antibiotic resistance genes and contains minimal foreign DNA. …”
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The Novel Role of Healing from Bacterial Infections of Lower Limb Open Fractures by X-Ray Exposure by Ali A. Mahdi, Tuqa S. Al-Salmani, Mustafa M. Al-Qaisi

“…All the bacterial isolates recorded high levels of antibiotic resistance against most tested antibiotics. Wound cultures of grade II fractures appeared sterile after the first X-ray exposure, and these wounds were infected with S. aureus or P. aeruginosa. …”
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Isolation and characterization of a novel lytic phage K14-2 infecting diverse species of the genus Klebsiella and Raoultella by Seomin Kang, Jeong-Eun Han, Young-Sik Choi, In-Chul Jeong, Jin-Woo Bae, Jin-Woo Bae, Jin-Woo Bae

“…Notably, the genera Klebsiella and Raoultella are of concern due to their association with human infections and the transfer of antibiotic-resistance genes. Phage therapy has recently garnered attention as a novel approach to treating these infections. …”
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Metagenomic insights into pathogenic bacteria and antimicrobial resistance in offshore coastal sediments – An example from Gulf waters by Nazima Habibi, Saif Uddin, Hanan Al Sarawi, Ahmad Aldhameer, Montaha Behbehani, Saja Fakhraldeen, Waleed Al-Zekri, Nasreem Abdulrazzack, Farhana Zakir, Anisha Shajan

“…Globally, indiscriminate waste discharges in marine environments are one of the key contributors to pathogenic bacteria, antibiotic resistance genes (ARGs), and mobile genetic elements (MGEs). …”
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The periplasmic protein HslJ is the first-line of defense against oxidative stress in Acinetobacter baumannii by Daniela Scribano, Martina Pasqua, Dolores Limongi, Lucia Nencioni, Anna Teresa Palamara, Cecilia Ambrosi

“…Its adaptability to antibiotic resistance and tolerance to various stresses, including reactive oxygen species (ROS), contribute to its persistence in healthcare environments. …”
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Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents by Jie Dai, Qianyue Li, Ziyi Li, Zhonglin Zang, Yan Luo, Chenghe Zhou

“…The overprescription of antibiotics in medicine and agriculture has accelerated the development and spread of antibiotic resistance in bacteria, which severely limits the arsenal available to clinicians for treating bacterial infections. …”
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6-Bromoindole- and 6-Bromoindazole-Based Inhibitors of Bacterial Cystathionine γ-Lyase Containing 3-Aminothiophene-2-Carboxylate Moiety by Roman A. Novikov, Dmitry N. Platonov, Alexander Yu. Belyy, Konstantin V. Potapov, Maxim A. Novikov, Yury V. Tomilov, Olga I. Kechko, Tatiana A. Seregina, Anastasia S. Zemskaya, Pavel N. Solyev, Vladimir A. Mitkevich

“…Their action can significantly enhance the antibacterial effect and limit the spread of antibiotic resistance through inhibition of bacterial cystathionine-γ-lyase. …”
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Effects of butyric acid and Protoxin probiotic in the feeding of Siberian sturgeon (Acipenser baerii) by Rasool Zare, Abdolmohammad Abedian Kenari

“…However, scientific knowledge and public concerns about the development of antibiotic resistance have led to a global reduction or prohibition of these compounds. …”
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Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting by Douglas Slain, Arif R. Sarwari, Karen O. Petros, Richard L. McKnight, Renee B. Sager, Charles J. Mullett, Alison Wilson, John G. Thomas, Kathryn Moffett, H. Carlton Palmer, Harakh V. Dedhia

“…Despite variability in antibiotic usage from the stewardship efforts, we were overall unable to show statistical relationships with P. aeruginosa resistance rate. Conclusion. Antibiotic resistance in the ICU setting is complex. Multimodal stewardship efforts attempt to prevent resistance, but such programs clearly have their limits.…”
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Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy by Benjamine Lapras, Camille Merienne, Emma Eynaud, Léa Usseglio, Chloé Marchand, Mathieu Médina, Camille Kolenda, Thomas Briot, Frédéric Laurent, Fabrice Pirot, PHAGEinLYON

“…Abstract Phage therapy uses viruses (phages) against antibiotic resistance. Tailoring treatments to specific patient strains requires stocks of various highly concentrated purified phages. …”
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Transition from irrigation with untreated wastewater to treated wastewater and associated benefits and risks by Benjamin J. Heyde, Melanie Braun, Leila Soufi, Kathia Lüneberg, Sara Gallego, Wulf Amelung, Katharina Axtmann, Gabriele Bierbaum, Stefanie P. Glaeser, Elisabeth Grohmann, René Arredondo-Hernández, Ines Mulder, Dipen Pulami, Kornelia Smalla, Christiane Zarfl, Christina Siebe, Jan Siemens

“…While this transition reduces many health risks, it may decrease crop yields, and soil carbon storage, cause a release of accumulated pollutants from soils, and increase the spread of antibiotic resistance in the environment. A holistic view on multiple SDGs is necessary to maximize benefits and minimize risks of wastewater treatment for irrigation.…”
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Serotype distribution and antimicrobial susceptibility of Streptococcus suis isolates from porcine diagnostic samples in Hungary, 2020–2023 by Ervin Albert, István Emil Kis, Krisztián Kiss, Katalin K-Jánosi, Tamás Révész, Imre Biksi

“…In contrary, the presence of several resistotypes could indicate the problem of antibiotic resistance in the future.…”
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In silico characterization of defense system hotspots in Acinetobacter spp. by Wenjing Yi, Ning Zhu, Zhihan Peng, Xiao Chu, Haotian Sun, Lei Song, Zhimin Guo, Arnab Pain, Zhaoqing Luo, Qingtian Guan

“…This knowledge lays the foundation for developing targeted interventions  to combat antibiotic resistance Acinetobacter baumannii.…”
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Tetracycline and chloramphenicol exposure induce decreased susceptibility to tigecycline and genetic alterations in AcrAB-TolC efflux pump regulators in Escherichia coli and Klebsi... by Nian Anwar Nasralddin, Mehri Haeili, Sasan Karimzadeh, Fatemeh Alsahlani

“…Unaltered acrB expression level in some strains indicates possible contribution of other efflux pumps or non-efflux-based mechanisms in the development of multiple- antibiotic resistance phenotype.…”
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Hospital-Based Air-Borne and Surface-Borne Bacterial Pathogens and Their Antimicrobial Profiles in Wolaita Sodo, Southern Ethiopia by Chemere Madebo, Admasu Haile, Temesgen Eticha, Fithamlak Solomon

“…A 12.5–100% range of antibiotic resistance levels was detected for all Gram-negative surface-borne bacterial pathogens. …”
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Molecular genetic and bacteriological methods of bovine mycoplasmosis diagnosis by E. V. Remizova, A. V. Gorbatov, L. K. Semina, Z. A. Skulyabina, N. V. Shmidt, G. A. Baldicheva, N. N. Avduevskaya

“…In addition, during microbiological testing, it is possible to assess the antibiotic resistance of mycoplasma isolates, thereby developing an optimal and high-quality scheme of the disease treatment and prevention.…”
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Genotypic and Phenotypic Characterizations of Methicillin-Resistant Staphylococcus aureus (MRSA) on Frequently Touched Sites from Public Hospitals in South Africa by Siyethaba Mkhize, Daniel G. Amoako, Christiana O. Shobo, Oliver T. Zishiri, Linda A. Bester

“…This study aimed to ascertain the prevalence, genetic relatedness, antibiotic resistance, and virulence profile of MRSA on some frequently touched hospital sites in South Africa. …”
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Changes in incidence and epidemiology of antimicrobial resistant pathogens before and during the COVID-19 pandemic in Germany, 2015–2022 by Jonathan H. J. Baum, Achim Dörre, Felix Reichert, Ines Noll, Marcel Feig, Tim Eckmanns, Mirco Sandfort, Sebastian Haller

“…Methods We used two independent datasets, statutory surveillance and laboratory-based Antibiotic Resistance Surveillance (ARS). We included statutory notifications of infections/colonisations of carbapenem-resistant Acinetobacter spp., Klebsiella pneumoniae, Escherichia coli (CRA/CRKP/CREC) and invasive MRSA. …”
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Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review by Noel Gahamanyi, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Erick V. G. Komba

“…Electronic databases, namely, PubMed, Google Scholar, Research4life-HINARI Health, and Researchgate.net, were searched using the following search terms “thermophilic Campylobacter,” “Campylobacter jejuni,” “Campylobacter coli,” “diarrhea/diarrhoea,” “antimicrobial resistance,” “antibiotic resistance,” “humans,” “animals,” “Sub-Saharan Africa,” and “a specific country name.” …”
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