Establishment of a rapid and quantitative method for detecting the range of infection exposure in preclinical dental education by Ayaka Ueda, Yuki Shinoda-Ito, Kazu Takeuchi-Hatanaka, Takashi Ito, Shintaro Ono, Kimito Hirai, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba

“…The spread of infections such as SARS-CoV-2, antibiotic-resistant bacteria, and oral bacteria are sometimes lethal for medically compromised patients. …”
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Hexagonal zinc oxide nanoparticles: a novel approach to combat multidrug-resistant Enterococcus faecalis biofilms in feline urinary tract infections by Alaa H. Sewid, Alaa H. Sewid, Mohamed Sharaf, Mohamed Sharaf, Azza S. El-Demerdash, Sherif M. Ragab, Fatimah O. Al-Otibi, Mohamed Taha Yassin, Chen-Guang Liu

“…The synergistic effects of the combined formulation may offer a novel approach to overcome antibiotic resistance and improve the treatment outcomes of E. faecalis UTIs in domestic cats.…”
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Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…Conclusion Our meta-analysis suggests that PEDD is a potentially effective and safe intervention for SI. Optimizing antibiotic discontinuation and postoperative care strategies may contribute to reducing reoperation rate. …”
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Bearberry in the treatment of acute uncomplicated cystitis (BRUMI): protocol of a multicentre, randomised double-blind clinical trial by Péter Hegyi, Noémi Gede, Szilárd Váncsa, Barbara Tóth, András Jávorházy, Péter Nyirády, Boglárka Csupor-Löffler, Péter Birinyi, George Zhanel, Kurt Naber, Reinhard Länger, Nóra Vörhendi, Dezső Csupor

“…The antimicrobial activity of its extracts and some of its individual constituents has been observed in vitro; however, the efficacy of bearberry compared with standard antimicrobial therapy has not been assessed yet.Objective The objective of the study is to assess the safety and non-inferiority of bearberry as an alternative therapy in the treatment of acute uncomplicated cystitis in comparison with standard antibiotic therapy (fosfomycin).Methods and analysis This is a randomised controlled double-blinded multicentre trial. …”
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Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study by Ridhofar Akbar Khusnul Abdillah, Theresia Indah Budhy, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Muhammad Luthfi, Ninik Mas Ulfa, Albertus Putera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor, Alexander Patera Nugraha

“…Administering doxycycline may be the solution, but long-term side effects result in antibiotic resistance. Roselle flowers (Hibiscus sabdariffa) possess beneficial active phytochemical substances, which may have potential as an OMI peri-implantitis alternative therapy. …”
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Multiple viral infections and antimicrobial use in hospitalized children with respiratory illness during pandemic and early post-pandemic era, Taiwan by Chyi-Liang Chen, Yi-Ching Chen, Hsuan-Ling Hsiao, Yi-Jung Chang, Hsin-Chieh Li, Merve Arslan Aydin, Cheng-Hsun Chiu

“…Pediatric physicians continued to use antibiotics for febrile symptoms in hospitalized children with respiratory illness, even when viral pathogens were identified.…”
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Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

“…However, we encountered challenges that complicated pleural infection interpretation, including: (i) uncertainties regarding microbial pathogenicity and the impact of prior antibiotic therapy on diagnostic performance; (ii) lack of a clinical diagnostic gold-standard for molecular performance comparisons; (iii) potential microbial contamination during specimen collection or processing; and (iv) difficulties distinguishing background microbial noise from true microbial signal in low-biomass specimens. …”
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The MIL-125(Ti)/Co3O4 towards efficiently removing tetracycline by synergistic adsorption-photocatalysis roles by Qiuyang Dai, Guicheng Gao, Jijun Tang, Rongfei Jiang, Shijiao Sun, Yonglin Ye, Shiyun Li, Rong Xie, Jiaoxia Zhang

“…The efficient removal of antibiotic residues from water has become a significant concern in environmental management. …”
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Factors Predicting Ventilator Dependence in Patients with Ventilator-Associated Pneumonia by Chia-Cheng Tseng, Kuo-Tung Huang, Yung-Che Chen, Chin-Chou Wang, Shih-Feng Liu, Mei-Lien Tu, Yu-Hsiu Chung, Wen-Feng Fang, Meng-Chih Lin

“…Results from the Kaplan-Meier method indicate that initial therapy with antibiotics could increase the ventilator weaning rate (log Rank test, P<0.001). …”
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Insights from a Genome-Wide Study of <i>Pantoea agglomerans</i> UADEC20: A Promising Strain for Phosphate Solubilization and Exopolysaccharides Production by Edith Elizondo-Reyna, Humberto Martínez-Montoya, Yahaira Tamayo-Ordoñez, María Antonia Cruz-Hernández, Mauricio Carrillo-Tripp, María Concepción Tamayo-Ordoñez, Gerardo de Jesús Sosa-Santillán, José Antonio Rodríguez-de la Garza, Mario Hernández-Guzmán, Virgilio Bocanegra-García, Erika Acosta-Cruz

“…The comprehensive set of genes supporting phosphate solubilization, EPS synthesis, and secretion, along with its low virulence and antibiotic resistance levels, justify further research for its potential biotechnological application and possible use as a plant growth-promoting agent in the field. …”
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Virulence profile of carbapenem-resistant Klebsiella pneumoniae strains by an in vivo model of Galleria mellonella by María Guembe, Rama Hafian, Marta Díaz-Navarro, Andrés Visedo, Flavio De Maio, Fulvia Pimpinelli, Ilaria Cavallo, Mauro Truglio, Francesca Sivori, Enea Gino Di Domenico

“…ABSTRACT Klebsiella pneumoniae is a significant healthcare-associated pathogen, notable for its diverse virulence and antibiotic resistance profiles. This study aimed to characterize the genotypic and phenotypic diversity of K. pneumoniae isolates and evaluate their virulence using the Galleria mellonella model. …”
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Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase by Valeriya Bezkorovayna, Brooke K. Hayes, Francesca N. Gillett, Amy Wright, David I. Roper, Marina Harper, Sheena McGowan, John D. Boyce

“…The increasing development of antibiotic resistance in this organism is a global health concern. …”
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Impact of Early-Life Microbiota on Immune System Development and Allergic Disorders by Norbert Dera, Katarzyna Kosińska-Kaczyńska, Natalia Żeber-Lubecka, Robert Brawura-Biskupski-Samaha, Diana Massalska, Iwona Szymusik, Kacper Dera, Michał Ciebiera

“…In the subsequent stages of a child’s life, breastfeeding, diet and the use of antibiotics influence the state of eubiosis, which determines proper growth and development from the neonatal period to adulthood. …”
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Genetic determinants of silver nanoparticle resistance and the impact of gamma irradiation on nanoparticle stability by Amira M. Mahfouz, Walaa A. Eraqi, Hala Nour El Din El Hifnawi, Alaa El Din Shawky, Reham Samir, Mohamed A. Ramadan

“…Abstract Background One of the main issues facing public health with microbial infections is antibiotic resistance. Nanoparticles (NPs) are among the best alternatives to overcome this issue. …”
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Correction of Dysbiosis in Diversion Proctitis: Possibilities of Intraluminal Sanitation and the Prevention of Complications after Reconstructive Surgery by V. S. Groshilin, D. V. Martynov, Yu. L. Naboka, M. Yu. Bakulyarov, G. A. Mrykhin

“…In the control group (33 patients), routine methods for preventing anastomotic leakage and antibiotic prophylaxis were used. A comparative analysis of the number and severity of purulent-septic complications (taking into account the possibility of their relief), as well as the quality and rate of intestinal dysbiosis relief and the manifestations of diversion proctitis, was carried out.Results. …”
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The kinetics of maternal and self-developed Streptococcus suis-specific antibodies by Sandra Vreman, Rutger Jansen, Mikael Bastian, Patricia Beckers, Miriam van Riet, Helmi Fijten, Jan Fledderus, Astrid de Greeff, Hélène Winkelman, Norbert Stockhofe-Zurwieden, Lluís Fabà, Henk J. Wisselink, Manouk Vrieling

“…Abstract Background Streptococcus suis (S. suis) infections are responsible for a large disease burden in piglets during the nursery phase, compromising animal welfare and increasing antibiotic use. The immune gap caused by decreased maternal-derived antibodies (MDA) and insufficient levels or functionality of acquired antibodies in weaned pigs could play a role in the increased susceptibility to S. suis infections. …”
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Evaluation and Management of Patients with Hematoma After Gynecologic and Obstetric Surgery by Bekir Kahveci, Mehmet Obut, Serhat Ege, Mete Sucu, Nurullah Peker, Osman Uzundere, Gaye Kahveci, Mehmet Sukru Budak

“…In 10 (33.3%) patients, antibiotics were included in the treatment due to infection. …”
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Clarithromycin-Associated Acute Liver Failure Leading to Fatal, Massive Upper Gastrointestinal Hemorrhage from Profound Coagulopathy: Case Report and Systematic Literature Review by Ahmed I. Edhi, Seifeldin Hakim, Christienne Shams, Damanpreet Bedi, Mitual Amin, Mitchell S. Cappell

“…While erythromycin has caused numerous cases of acute liver failure (ALF), clarithromycin, a similar macrolide antibiotic, has caused only six reported cases of ALF. …”
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Prevalence of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Ethiopia: A Systematic Review and Meta-Analysis by Teklehaimanot Kiros, Lema Workineh, Tegenaw Tiruneh, Tahir Eyayu, Shewaneh Damtie, Debaka Belete

“…Their rapid spread in Ethiopia is associated with a lack of regular surveillance and antibiotic stewardship programs. Isolates of ESBL-PE from different regions of Ethiopia were searched exhaustively. …”
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Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers by Gaetano Zizzo, Gabriele Guazzardi, Daniela Bompane, Francesco Di Terlizzi, Giorgio Rotola, Ilario Stefani, Michela Medugno, Mario Bucalo, Antonino Mazzone

“…From 2016 to 2023, MDR+ sepsis frequency declined, due to decreased resistance to several antibiotic classes, such as cephalosporins, fluoroquinolones, and aminoglycosides; however, carbapenemase- and extended-spectrum beta-lactamase-producing Gram-negative bacteria, as well as vancomycin-resistant enterococci, increased, as did the frequency of polymicrobial sepsis following the COVID-19 outbreak.ConclusionThis work provides novel insights into sepsis management in internal medicine units, highlighting the need for validated biomarkers and implemented therapies in this scenario.…”
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