Investigation of some anaerobic bacteria in the sputum of cystic fibrosis patients and healthy people in Tehran, Iran by Homa Hamayeli, Ahya Abdi-Ali, Bahareh Attaran, Morvarid Shafiei, Mohammadreza Modaresi

“…The results of Spearman's correlation also showed an inverse relationship between age and gender (men) with disease and a direct relationship between antibiotic use and disease. Conclusions: The abundance of potentially beneficial species of Bifidobacterium and Prevotella was lower in CF than in healthy people. …”
Get full text

Salmonella enteridis Septic Arthritis: A Report of Two Cases by Esat Uygur, Krishna Reddy, Feyza Ünlü Özkan, Salih Söylemez, Özlem Aydin, Serkan Şenol

“…The gold standard treatment of septic arthritis is joint debridement, antibiotic therapy according to the culture results, and physiotherapy, which should start in the early postoperative period to prevent limitation of motion. …”
Get full text

A CDFT-Based Computational Peptidology (CDFT-CP) Study of the Chemical Reactivity and Bioactivity of the Marine-Derived Alternaramide Cyclopentadepsipeptide by Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik

“…Alternaramide is a cyclic pentadepsipeptide isolated from marine sources that has been shown to present weak antibiotic activity against Bacillus subtilis and Staphylococcus aureus as well as inhibitory effects on inflammatory mediator expressions. …”
Get full text

Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…Besides, the increasing attention of doctors and scientists is attracted to the issue intestinal microflora changes at antibiotic treatment. Conclusion. «The Human microbiome project» is implemented within identification and characterization of the microorganisms associated to the different anatomical regions of the human body tasks of the project include the study of inand interindividual microbiome disorders and their possible effect on the human health. …”
Get full text

A Para-Canalicular Abscess Resembling an Inflamed Chalazion by Diamantis Almaliotis, Elias Nakos, Thomas Siempis, Triantafyllia Koletsa, Ioannis Kostopoulos, Maria Chatzipantazi, Vasileios Karampatakis

“…A surgical excision was performed followed by administration of local antibiotic therapy. The histopathological examination of the extracted mass revealed the existence of actinomycosis. …”
Get full text

Comparison of Different Phenotypic Tests versus PCR in the Detection of Carbapenemase-Producing Pseudomonas aeruginosa Isolates in Hamadan, Iran by Masoumeh Beig, Mohammad Taheri, Mohammad Reza Arabestani

“…Moreover, among the carbapenem antibiotics, the highest resistance was to imipenem (49.4%). …”
Get full text

Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes by Mahnoor Mahnoor, Syeda Aina Ali, Saira Nasir, Moiz Azmat, Hafiz Muhammad Umer Farooqi

“…The patient was managed with third-generation antibiotics over two weeks, leading to full recovery without surgical intervention. …”
Get full text

Incontinentia Pigmenti Misdiagnosed as Neonatal Herpes Simplex Virus Infection by Fahimeh Abdollahimajd, Minoo Fallahi, Mohammad Kazemian, Yalda Nilipour, Mitra Radfar, Sedigheh Tahereh Tehranchi

“…She was admitted in the maternity hospital that was born and was treated by antibiotic and acyclovir for 11 days. Then, she readmitted for her distributed vesicular lesions. …”
Get full text

Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes by Maria Fransiska Priska Yulianti, Anita Lidesna Shinta Amat, Regina Marvina Hutasoit, Prisca Deviani Pakan

“…The inappropriate use of antibiotics can lead to resistance, necessitating the search for alternative therapies from plants with high antibacterial potential. …”
Get full text

Flavonoid Compounds from Ethanol Extract of Sungkai Leaves (Peronema canescens. Jack) and Antibacterial Activity Test Against Staphylococcus epidermidis and Escherchia coli by Nindita Clourisa Amaris Susanto, Jammes Ardhica, Nelson, Madyawati Latief

“… The rise of antibiotic-resistant bacteria has intensified the global search for alternative antimicrobial agents, particularly from natural sources. …”
Get full text

Diagnostic Challenges of Helicobacter pylori Infection in Ethiopia: A Community-Based Cross-Sectional Study by Esayas Kebede Gudina, Hiwot Amare, Solomon Ali, Melkamu Berhane Arefayine, Dagmawi Tewolde, Million Tesfaye Eshete, Mulusew Gerbaba Jebena, Andreas Wieser, Guenter Froeschl, Markos Tesfaye, Hailemichael Desalegn, Mulatu Gashaw

“…With these methods, it will be hard to ensure adequate diagnosis and early treatment of H. pylori infection, as well as rational antibiotic use.…”
Get full text

Short-Term Effect of Continuous Subcutaneous Insulin Infusion and Multiple Daily Injection in Perioperative Patients with Type 2 Diabetes Mellitus by Wei Song, Jianxuan Wen, Jinming Zhang, Meng Luo, Yue Hu, Yu Zhang, Guanjie Fan, Ling Zhao

“…Regarding slack variables, with higher surgical levels, the CSII group was closer to the ideal state than the MDI group, which indicated in improving the average fasting blood glucose (AFBG), antibiotic use days (AUD), preoperative blood glucose control time (PBGCT), first postoperative day fasting blood glucose (FPDFBG), and postoperative hospitalization days (PHD). …”
Get full text

Challenges in Diagnosis and Management of Altered Mental Status in the Setting of Urosepsis and Hydrocephalus Secondary to an Occlusive Cyst of the Fourth Ventricle: A Case Report by Matthew Van Ligten, Miles Hudson, Jonathon J. Parker, Wayne A. Martini

“…The acute management involved empirical antibiotic therapy for associated sepsis, followed by the placement of an external ventricular drain for cerebrospinal fluid diversion and sampling, including cytology and cell counts, given the concern for tonsillar herniation with a lumbar puncture. …”
Get full text

Diagnosis of Vitreoretinal Aspergillosis with Transvitreal Retinochoroidal Biopsy by Krishi Peddada, Nida M. Khan, Jascha Rubin, Haykanush Zakaryan, Yaobin Liu, Nikolay Popnikolov, Roshun Sangani, Weiye Li

“…However, the patient’s vision and mental status continued to clinically decline despite being started on intravitreal and systemic antibiotic and antifungal therapy. Neuroimaging revealed rim-enhancing brain lesions. …”
Get full text

Synthesis, antibacterial evaluation and in silico studies of novel 2-(benzo[d]thiazol-2-yl)-N-arylacetamides and their derivatives as potential DHFR inhibitors by Nadia Hanafy Metwally, Galal Hamza Elgemeie, Aya Ragab Abdelrazek, Salwa Magdy Eldaly

“…Additionally, compounds 2c and 4m showed enzyme inhibition against dihydrofolate reductase in Escherichia coli with greater potency (IC50 for 2c = 3.796 µM, IC50 for 4m = 2.442 µM) than the standard antibiotic trimethoprim (IC50 = 8.706 µM). Investigation of the physicochemical properties of the newly compounds exhibited their better ADME properties that can be developed for the discovery of new antibacterial agents. …”
Get full text

Biofilm Formation and blaOXA Genes Detection Among Acinetobacter baumannii from Clinical Isolates in a Tertiary Care Kirtipur Hospital, Nepal by Upasana Ghimire, Rupesh Kandel, Mary Neupane, Sanjit Shrestha, Sudeep K C, Santosh Khanal, Dev Raj Joshi

“… (1) Background: Acinetobacter baumannii has emerged as a leading cause of nosocomial infections as they are capable of evolving resistance to various classes of antibiotics. The ability of A. baumannii to form biofilm might also be associated with increased antibiotic resistance and hence treatment failure. …”
Get full text

Unveiling promising sepsis biomarkers: a clinical perspective by Hong Zhang, Junpeng Zhao, Zhiping Wang, Mengxiang Huang, Zhonghua Tan, Feng Jiang, Yuhong Zhou, Linhua Wang, Mingbing Xiao

“…It can be used to guide antibiotic use but should not be used as a standalone diagnostic indicator. …”
Get full text

Antifungal Susceptibility and Biofilm Production of Candida spp. Isolated from Clinical Samples by Munmun B. Marak, Biranthabail Dhanashree

“…Presence of other risk factors such as diabetes mellitus, history of antibiotic use, and any urinary tract instrumentations was also recorded. …”
Get full text

A Rare Case of Pneumonia Caused by Shewanella putrefaciens by Rajshree Patel, Albin Abraham, Johnson Thomas, Wanqing Zhi, Shadab Ahmed, Janice Verley

“…On the second day of hospitalization, he was diagnosed to have pneumonia based on the clinical, radiological, and laboratory findings. Empirical antibiotic treatment with vancomycin and piperacillin/tazobactam combination was initiated. …”
Get full text

Genomic characterization of antimicrobial-resistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombia. by María Isabel García-Álvarez, Juana L Vidal, Pilar Donado-Godoy, Jared Smith, Nikki Shariat, María Fernanda Valencia, Luis M Gómez-Osorio, Sara López-Osorio, Jenny J Chaparro-Gutiérrez

“…Genes encoding resistance were found for 10 different groups of antibiotics (beta-lactam, aminoglycosides, chloramphenicol, rifampicins, lincosamides, fluoroquinolones, tetracyclines, sulfonamides and trimethoprim). …”
Get full text