Optimization of the Antibacterial Activity of a Three-Component Essential Oil Mixture from Moroccan <i>Thymus satureioides</i>, <i>Lavandula angustifolia</i>, and <i>Origanum major... by Amine Elbouzidi, Mohamed Taibi, Naoufal El Hachlafi, Mounir Haddou, Mohamed Jeddi, Abdellah Baraich, Saad Bougrine, Ramzi A. Mothana, Mohammed F. Hawwal, Waleed A. Alobaid, Abdeslam Asehraou, Bouchra El Guerrouj, Hanae Naceiri Mrabti, Francois Mesnard, Mohamed Addi

“…Background/Objectives: The rise of antibiotic-resistant pathogens has become a global health crisis, necessitating the development of alternative antimicrobial strategies. …”
Get full text

An In Vitro Synergistic Interaction of Combinations of Thymus glabrescens Essential Oil and Its Main Constituents with Chloramphenicol by Budimir S. Ilić, Branislava D. Kocić, Vojislav M. Ćirić, Olga G. Cvetković, Dragoljub L. Miladinović

“…The essential oil exhibited in vitro antibacterial activity against all tested bacterial strains, but the activities were lower than those of the standard antibiotic and thymol. A combination of  T. glabrescens oil and chloramphenicol produced a strong synergistic interaction (FIC indices in the range 0.21–0.87) and a substantial reduction of the MIC value of chloramphenicol, thus minimizing its adverse side effects. …”
Get full text

Uji Daya Hambat Isolat Actinomycetes sebagai Antibakteri terhadap Pertumbuhan Pseudomonas aeruginosa ATCC 27853 secara In Vitro by Saskia Arientika Wahyuningrum, Meiskha Bahar, Andri Pramesyanti Pramono

“…Pneumonia is a lung parenchymal infection caused by Pseudomonas aeruginosa.It is Gram negative bacteria that have developed antibiotic resistance. Actinomycetes are Gram-positive bacteria that produce secondary metabolites which have the ability as antimicrobial. …”
Get full text

Primary Cutaneous Cryptococcosis Treated with Debridement and Fluconazole Monotherapy in an Immunosuppressed Patient: A Case Report and Review of the Literature by Jennifer Wang, Luther Bartelt, Deborah Yu, Anjali Joshi, Bradley Weinbaum, Tiffany Pierson, Michael Patrizio, Cirle A. Warren, Molly A. Hughes, Gerald Donowitz

“…This case highlights the importance of early recognition of aggressive cellulitis that fails standard empiric antibiotic treatment in an immunocompromised patient. …”
Get full text

Mutant Prevention Concentrations of Imipenem and Meropenem against Pseudomonas aeruginosa and Acinetobacter baumannii by E. Dahdouh, S. H. Shoucair, S. E. Salem, Z. Daoud

“…Detection of the mechanisms of resistance was performed using Antibiotic Susceptibility Testing, Double Disk Synergy, disk antagonism, addition of NaCl to the medium, addition of PBA or EDTA to Carbapenem disks, addition of PBA to Cefoxitin disks, and CCCP test for 10 Pseudomonas spp. and Acinetobacter baumannii strains. …”
Get full text

Administration of Rhodiola kirilowii Extracts during Mouse Pregnancy and Lactation Stimulates Innate but Not Adaptive Immunity of the Offspring by Sławomir Lewicki, Ewa Skopińska-Różewska, Aleksandra Brewczyńska, Robert Zdanowski

“…The use of antibiotics during pregnancy and lactation is associated with an increased risk of developmental disorders. …”
Get full text

From Bench to Bedside to Bug: An Update of Clinically Relevant Advances in the Care of Persons with Helicobacter pylori Associated Diseases by N Chiba, ABR Thomson, P Sinclair

“…The one-week proton pump inhibitor-based triple regimens remain the gold standard of H pylori therapy, but some of the ranitidine bismuth citrate plus two antibiotic regimens also achieve an 80% H pylori eradication rate on an intention-to-treat basis. …”
Get full text

Enhanced Isolation of Streptomyces from Different Soil Habitats in Calamba City, Laguna, Philippines using a Modified Integrated Approach by Jhon Wilson A. Antido, Fresthel Monica M. Climacosa

“…Streptomyces species are considered to be the most prolific sources of various bioactive secondary metabolites that are important for antibiotic production. Here, we describe a modified integrated approach to isolate Streptomyces species from diverse soil habitats, such as dumpsite, garden, forest, grassland, and riverside in Calamba City, Laguna, Philippines. …”
Get full text

New Bioactive Metabolites from the Thermophilic Fungus Penicillium sp. Isolated from Ghamiqa Hot Spring in Saudi Arabia by Raha Orfali, Shagufta Perveen

“…All isolated metabolites were studied for their antibiotic effect against several pathogenic bacteria and for their cytotoxicity against the lymphoma human cancer cell line HTB-176. …”
Get full text

Prevalence and Antimicrobial Susceptibility Patterns of Neisseria gonorrhoeae among Suspected Patients Attending Private Clinics in Jimma, Ethiopia by Addisu Sahile, Lule Teshager, Minale Fekadie, Mulatu Gashaw

“…In most African countries including Ethiopia, Neisseria gonorrhoeae infections were diagnosed clinically and its antibiotic susceptibility was rarely tested. This study aimed to determine the prevalence and antimicrobial susceptibility patterns of N. gonorrhoeae among suspected patients attending private clinics in Jimma, Ethiopia. …”
Get full text

A Case of Early Disseminated Neurological Lyme Disease Followed by Atypical Cutaneous Manifestations by Vamsi Kantamaneni, Vikas Sunder, Mohammad Bilal, Scott Vargo

“…The patient’s symptoms including facial droop resolved within 24 hours of antibiotic therapy. Polymerase chain reaction of the blood, IgM ELISA, and IgM Western blot testing for LD came back positive a few days after initiation of therapy. …”
Get full text

Clinical case of treatment of subacute endocarditis in a patient after occluder closing of the patent foramen ovale by G.I. Kovtun, S.O. Sheludko, D.O. Loskutov, H.Yu. Melnyk

“…The total duration of the antibiotic therapy was 5 weeks…”
Get full text

Toward <i>Mycobacterium tuberculosis</i> Virulence Inhibition: Beyond Cell Wall by Maria S. Kotliarova, Mikhail S. Shumkov, Anna V. Goncharenko

“…<i>Mycobacterium tuberculosis</i> (Mtb) is one of the most successful bacterial pathogens in human history. Even in the antibiotic era, Mtb is widespread and causes millions of new cases of tuberculosis each year. …”
Get full text

Meropenem Continuous Infusion in a Septic Patient with Periprosthetic Infection and End-Stage Renal Disease Undergoing Prolonged Intermittent Renal Replacement Therapy by Assiya Kadralinova, Maiya Konkayeva, Serik Dzhandayev, Aidos Konkayev

“…This case report highlights the use of continuous infusion of meropenem in a 42-year-old septic female patient with periprosthetic infection and end-stage renal disease receiving prolonged intermittent renal replacement therapy (PIRRT). Antibiotic infusion in patients receiving renal replacement therapy has its own peculiarities. …”
Get full text

Pyelonephritis and Bacteremia Caused by Klebsiella variicola following Renal Transplantation by Cody Lo, Shazia Masud, Gregory D. Deans

“…Despite the risk of allograft failure in this circumstance, this patient was successfully treated with a 14-day course of antibiotic therapy.…”
Get full text

Ovarian Fibroma as a Possible Cause of Fever of Unknown Origin by İkbal Kaygusuz, Ayla Eser, İlknur İnegöl Gümüş, İsmail Kırbaş, Kayıhan Akın, Hacer Haltas, Hasan Kafalı

“…Pus drainage was then planned but 3cc of serous material was drained from the adnexal mass with ultrasound-guide. Despite antibiotic therapy, her fever continued. She had a comprehensive work-up for FUO, including rheumatologic, infectious, and malignant etiologies. …”
Get full text

A two-strain TB model with multiplelatent stages by Azizeh Jabbari, Carlos Castillo-Chavez, Fereshteh Nazari, Baojun Song, Hossein Kheiri

“…A two-strain tuberculosis (TB) transmission model incorporating antibiotic-generated TB resistant strains and long and variable waiting periods within the latently infected class is introduced. …”
Get full text

Retained multiple contact lenses in a vulnerable dementia patient by Rohit SHARMA, Zuhair SHARIF

“…Treated ‘on and off ’ by various doctors and healthcare professionals with antibiotic drops for eight months with no improvement. …”
Get full text

Helicobacter pylori: From Bench to Bedside by N Chiba, A Matisko, P Sinclair, ABR Thomson

“…According to the European (Mäastricht) recommendations, if a single treatment attempt with PPI plus two antibiotics fails, PPI plus BMT is recommended.…”
Get full text

Noninvasive Monitoring of Pneumococcal Meningitis and Evaluation of Treatment Efficacy in an Experimental Mouse Model by Jagath L. Kadurugamuwa, Kshitij Modi, Jun Yu, Kevin P. Francis, Carlos Orihuela, Elaine Tuomanen, Anthony F. Purchio, Pamela R. Contag

“…Mice treated with the antibiotic survived infection, whereas all mice in untreated groups became moribund, first in the IC group then in the LP group. …”
Get full text