Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia by Ren-Hsuan Ku, Hsu-Feng Lu, Li-Hua Li, Li-Hua Li, Ting-Yu Yeh, Yi-Tsung Lin, Yi-Tsung Lin, Tsuey-Ching Yang

“…The contribution of rpoEc-chrR-chrA operon to oxidative stress alleviation and antibiotic susceptibility was evaluated using mutant constructs and stress-tolerance assays. …”
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Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit by Fei Wu, Yuanyuan Ying, Min Yin, Yi Jiang, Chongyang Wu, Changrui Qian, Qianqian Chen, Kai Shen, Cong Cheng, Licheng Zhu, Kewei Li, Teng Xu, Qiyu Bao, Junwan Lu

“…The whole genome encoded 34 antibiotic resistance genes including a newly identified chromosome-encoded florfenicol resistance gene named mdfA2. pR46-270, besides encoding 26 antibiotic resistance genes, carried four clusters of heavy metal resistance genes and several virulence-related genes or gene clusters. …”
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Pola Sensitifitas dan Resistensi Kuman Urin, Ujung Kateter dan Ujung Drain Pasien Resipient Transplantasi Ginjal di RS PGI Cikini Jakarta by Etriyel Myh, David Manuputty

“…Meropenem is the most sensitive antibiotic for urine infection and imipenem for infection from tip of drain. …”
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Impact of the COVID-19 Pandemic on Epidemiological Trends in Pediatric Cervical Abscess-Forming Infections by Shuhei Takahashi, Ai Kishino, Kentaro Miyai, Shigeru Takishima, Tae Omori, Hidehiro Furuno, Ryosei Iemura, Makoto Ono, Keisuke Ogasawara, Akito Sutani, Masayuki Nagasawa

“…No significant changes were found in the pharyngeal streptococcal antigen positivity rate, rate of oral antibiotic use before hospitalization, length of hospital stay, or duration of antibiotic administration before and after the COVID-19 pandemic. …”
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Probiotic potential and safety properties of Limosilactobacillus fermentum A51 with high exopolysaccharide production by Guangqiang Wei, Daodian Wang, Daodian Wang, Teng Wang, Gao Wang, Yunmei Chai, Yufang Li, Minhui Mei, Hao Wang, Aixiang Huang

“…PGAAP annotation identified 2,152 protein-encoding genes and 58 rRNAs, 15 tRNAs, and 5 5sRNAs. Hemolysis and antibiotic resistance tests, combined with the analysis of genes involved in antibiotic resistance, virulence factor, and hemolysins, suggested that L. fermentum A51 is safe. …”
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Susceptibility profile and associated factors of urinary tract infections among women with established preterm labor delivering at a tertiary teaching hospital in Eastern Uganda: a... by Abdirizak Ahmed Ifrah, Marie Pascaline Sabine Ishimwe, Carlos Antonio Batista Cedeño, Eilu Emmanuel, Theoneste Hakizimana

“…The effectiveness of antibiotics against common Urinary tract Infection (UTI) pathogens varied significantly. …”
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Blowhole Colostomy for Clostridium difficile-Associated Toxic Megacolon by Jeroen Kerstens, Ian Diebels, Charles de Gheldere, Patrick Vanclooster

“…This infection occurred under antibiotic coverage with amoxicillin-clavulanic acid, four days after laparoscopic sigmoidectomy in our hospital. …”
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Myocarditis Caused by Brucella melitensis in the Absence of Endocarditis: Case Report and Review of the Literature by Maria Lagadinou, Virginia Mplani, Dimitrios Velissaris, Periklis Davlouros, Markos Marangos

“…Clinicians should be aware of this clinical entity especially in endemic areas as appropriate antibiotic treatment is life-saving and may prevent serious cardiologic disorders.…”
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Influence of Aging and Immune Alterations on Susceptibility to Pneumococcal Pneumonia in the Elderly by Nathan Kang, Veedamali S. Subramanian, Anshu Agrawal

“…Management of <i>S. pneumoniae</i> infections in the elderly is challenging due to impaired antibody responses to polysaccharides and surface proteins, compounded by rising antibiotic resistance. The underlying mechanisms for increased susceptibility remain unclear, but age-related changes in the immune system, particularly in dendritic cells and T cells, are implicated. …”
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Metagenomics approaches for studying the human microbiome by Biniam Moges, Degisew Yinur Mengistu

“…Hence, metagenomics analysis is a powerful advanced technology for comprehensively studying human microbial composition and diversity, exploring novel and antibiotic resistance genes, microbial metabolic pathways, functional dysbiosis, and co-evolution of the microbiome with the host. …”
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First Pediatric Case of Tularemia after a Coyote Bite by Bruno B. Chomel, Jane A. Morton, Rickie W. Kasten, Chao-chin Chang

“…Pediatricians should be aware of this risk after a carnivore bite and implement appropriate antibiotic therapy, as amoxicillin/clavulanate potassium (Augmentin) may have prolonged the typical two to three days’ incubation period commonly observed for tularemia after an animal bite and was not effective in preventing clinical signs in this child. …”
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Ischemic Retinal Vasculitis Associated with Cataract Surgery and Intracameral Vancomycin by Lucas T. Lenci, Eric K. Chin, Christi Carter, Stephen R. Russell, David R. P. Almeida

“…We present a case of a 65-year-old woman who underwent uncomplicated phacoemulsification and posterior chamber intraocular lens implantation followed by intracameral antibiotic prophylaxis. Unlike prior reports, this report demonstrates a case of mild visual reduction and minimal inflammation with subtle but complete unilateral peripheral retinal ischemia associated with cataract surgery and intracameral vancomycin, suggesting a spectrum of toxicity that may be underrecognized.…”
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Effectiveness of iNTS vaccination in sub-Saharan Africa by Daniele Cassese, Nicola Dimitri, Gianluca Breghi, Tiziana Spadafina

“…Abstract Invasive non-Typhoidal Salmonella (iNTS) is one of the leading causes of blood stream infections in Sub-Saharan Africa, especially among children. iNTS can be difficult to diagnose, particularly in areas where malaria is endemic, and difficult to treat, partly because of the emergence of antibiotic resistance. We developed a mathematical model to evaluate the impact of a vaccine for iNTS in 49 countries of sub-Saharan Africa. …”
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Ovarian hyperstimulation syndrome. A case report by Práxedes de Regla Rojas Quintana, Sandra Gómez Fonseca, Alejandrina Najarro Navarro

“…For these reasons, the case of a patient who underwent medical and surgical treatment, with in vitro fertilization and embryo transfer, who developed severe ovarian hyperstimulation syndrome with pregnancy si presente Since the syndrome could not be controlled and worsened with pregnancy and sepsis, with changes in addition to hepatorenal dysfunction, it was decided to terminate the pregnancy at six weeks of gestation, since the patient's life was in danger, and antibiotic therapy was started for sepsis. After 25 days of hospitalization, she was discharged from the institution after recovery and was followed up by assisted reproduction consultation. …”
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Pancreas as an Occult Source of Recurrent Salmonella enteritidis Bacteremia in an Immunocompromised Patient by Don Bambino Geno Tai, Laxmi Upadhyay, Ruchika Jain, Robert Goldstein

“…She was treated with intravenous and oral antibiotics but still had recurrence of fevers and bacteremia. …”
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Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae. by Hedi Mammeri, Youssouf Sereme, Eya Toumi, Hélène Faury, David Skurnik

“…The increasing resistance of Gram-negative bacteria to last resort antibiotics, such as carbapenems, is particularly of concern as it is a significant cause of global health threat. …”
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Exogenous Pulmonary Surfactant as a Vehicle for Antimicrobials: Assessment of Surfactant-Antibacterial Interactions In Vitro by Alexei Birkun

“…Owing to its unique surface-active properties, an exogenous pulmonary surfactant may become a promising drug delivery agent, in particular, acting as a vehicle for antibiotics in topical treatment of pneumonia. The purpose of this study was to assess a mutual influence of natural surfactant preparation and three antibiotics (amikacin, cefepime, and colistimethate sodium) in vitro and to identify appropriate combination(s) for subsequent in vivo investigations of experimental surfactant/antibiotic mixtures. …”
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An Infected, Noncoronary, Bare Metal Stent Presenting as a Right Groin Abscess by Madiha Khan, Youssef Mourad, Alan Zeitlin, Martine Alice Louis, Syed Ali Rizvi, Kelly L. Cervellione

“…The patient was not an ideal candidate for explantation and bypass due to significant medical comorbidities and underwent local debridement and long-term antibiotic management instead. His postoperative course was uncomplicated, and he had a successful outcome with management utilizing antibiotics and debridement. …”
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Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection. by Zhihao Chen, Qiyuan Jin, Jinqi Zhong, Zonggang Xie, Qi Chen, Liubing Li, Jijie Li, Chenhao Zhao, Junfeng Wang, Xiaoying Tang, Mingxiao Han, Ru Li, Ziyuan Li, Zelei Tong, Min Wang, Hong Du, Haifang Zhang

“…Bone infections are mainly caused by S. aureus and require extensive surgical intervention and long-term antibiotic therapy. The host autophagy response is critical to the elimination of S. aureus infections. …”
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A Pharmacological and Toxicological Profile of Silver as an Antimicrobial Agent in Medical Devices by Alan B. G. Lansdown

“…Silver is used widely in wound dressings and medical devices as a broad-spectrum antibiotic. Metallic silver and most inorganic silver compounds ionise in moisture, body fluids, and secretions to release biologically active Ag+. …”
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