Antimicrobial Stewardship in the Pediatric Emergency Department: An Observational Pre-Post Study by Erika Silvestro, Ilaria Mussinatto, Antonia Versace, Marco Denina, Giulia Pruccoli, Raffaella Marino, Giulia Mazzetti, Lorenzo Scaglione, Federico Vigna, Alessandra Macciotta, Silvia Garazzino, Claudia Bondone

“…We recorded all systemic antibiotic prescriptions for children attending our pediatric ED from January to March and from July to September 2020. …”
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Confocal Microscopy for Detection of Intracellular Bacteria in Urine Samples of patients Suspected with Urinary Tract Infection: A Cross-sectional Observational Study by Bhagyashri Patil-Takbhate, Nilam Memane, Srikanth Tripathy, Nageswari Gandham, Shahzad Mirza

“…Hence diagnosis of IIB/IBC is crucial for the management of recurrent UTI and precise antibiotic therapy to avoid antibiotic resistance.…”
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Oral Fluoroquinolones in the Treatment of Pneumonia, Bronchitis and Sinusitis by Nicole Mittmann, Farah Jivraj, Angelina Wong, Alice Yoon

“…BACKGROUND: Despite a relatively large number of clinical studies comparing oral fluoroquinolones to one antibiotic class comparator, there is limited information on the relative efficacy of different fluoroquinolones.…”
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Clostridium difficile – an Important Opportunistic Pathogen in Healthcare-Associated Infections by Soohyoun Ahn, Amarat H. Simonne

“…One opportunistic pathogen, Clostridium difficile, has been getting more attention in recent years because of its association with antibiotic use and high death rate in the elderly. This factsheet will provide an overview of Clostridium difficile infection (CDI) with a focus on healthcare-associated infections. …”
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Facts about Wildlife Diseases: Ehrlichiosis by Yasmin Tavares, Samantha M. Wisely

“…In most cases, symptoms are mild, but sometimes if antibiotic treatment is delayed, it can cause severe illness and even death. …”
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Closed Catheter Drainage for Klebsiella pneumoniae Empyema Necessitans by Mohammed Ishaq, Abdullah Bahadi

“…Scarce evidence with regard to adult empyema necessitans with Klebsiella was found in the literature where adult cases were managed exclusively using combination of intravenous (IV) antibiotic and closed drainage, reporting such case can help guiding management for similar presentation.…”
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Facts about Wildlife Diseases: Ehrlichiosis by Yasmin Tavares, Samantha M. Wisely

“…In most cases, symptoms are mild, but sometimes if antibiotic treatment is delayed, it can cause severe illness and even death. …”
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Clostridium difficile – an Important Opportunistic Pathogen in Healthcare-Associated Infections by Soohyoun Ahn, Amarat H. Simonne

“…One opportunistic pathogen, Clostridium difficile, has been getting more attention in recent years because of its association with antibiotic use and high death rate in the elderly. This factsheet will provide an overview of Clostridium difficile infection (CDI) with a focus on healthcare-associated infections. …”
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Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance by Paul H Roy

“…The advent of antibiotics in clinical medicine has resulted in the emergence of multiresistant strains of bacteria. …”
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Binocular Diplopia: A Possible Adverse Effect of Fluoroquinolone Therapy by Mariama Touray, Victoria Ando, Erwin Samutelela, Jean-Philippe Zuber

“…We present an interesting case of a 41-year-old male with binocular diplopia most likely induced by the use of a fluoroquinolone antibiotic.…”
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Incomplete Kawasaki Disease Associated with Complicated Streptococcus pyogenes Pneumonia: A Case Report by Timothy Ronan Leahy, Eyal Cohen, Upton D Allen

“…The patient improved with antibiotic therapy and drainage of the empyema.…”
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Risk Factors of Multidrug-Resistant Bacteria in Lower Respiratory Tract Infections: A Systematic Review and Meta-Analysis by Gang Chen, Kailiang Xu, Fangyuan Sun, Yuxia Sun, Ziyuan Kong, Bangjiang Fang

“…Clinicians could take into account these factors when selecting antibiotics for patients and determine whether coverage for MDR bacteria is required. …”
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Efficient degradation of neomycin by Bacillus velezensis and Cupriavidus basilensis isolated from mangrove soil and pharmaceutical wastewater by Qian Yang, Wenzhuan Huang, Xue Yan, Qiang Ding, Jiaxin Liu, Bo Cheng, Tao Duan

“…Neomycin, an aminoglycoside antibiotic, is widely utilized for veterinary medicine in disease prevention. …”
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Bacterial Contaminants and Antibiogram of Ghana Paper Currency Notes in Circulation and Their Associated Health Risks in Asante-Mampong, Ghana by Denis Dekugmen Yar

“…This study profiled microbial flora and their antibiotic activities from Ghana paper currency (GH¢) notes in circulation in Mampong Municipal of Ashanti Region, Ghana. …”
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Visible-Light-Driven Degradation of Chloramphenicol Using CeO₂ Nanoparticles Prepared by a Supercritical CO₂ Route: A Proof of Concept by Maria Chiara Iannaco, Antonietta Mancuso, Stefania Mottola, Andrea Pipolo, Vincenzo Vaiano, Iolanda De Marco

“…Recently, the extensive use of antibiotics has unavoidably resulted in the discharge of significant quantities of these drugs into the environment, causing contamination and fostering antibiotic resistance. …”
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Vacuum-Assisted Closure and Muscle Flap as An Alternative Modality for Infected Wound After Orif of Tibial Fracture: Case Report by OK Ilham Abdullah Irsyam, Saraswati Hastika, Hendra Hendra, Andrew Budiartha Budisantoso, Tesar Akbar Nugraha

“…Discussion: SSI can be treated by applicating of appropriate antibiotic and surgical procedures. In this case, the infection was treated using third-generation cephalosporin antibiotic, debridement, dissection, and re-elevation of gastrocnemius muscle flap covering the exposed plate area in inferior, split skin graft above the muscle flap and VAC above skin graft with 75 mmHg pressure. …”
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Mucosal snare resection-endoscopic submucosal excavation for gastric submucosal tumors: a retrospective study (with video) by Wei Wei, Xiaolong Zheng, Yongli Ye, Hongxia Li, Yiping Hong, Jianting Cai

“…Propensity score matching (PSM) showed no significant differences in postoperative antibiotic use, fasting time, or intraoperative perforation between the two groups (P>0.05). …”
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Determinants of Deescalation Failure in Critically Ill Patients with Sepsis: A Prospective Cohort Study by Nawal Salahuddin, Lama Amer, Mini Joseph, Alya El Hazmi, Hassan Hawa, Khalid Maghrabi

“…In this prospective study of patients with sepsis/septic shock, patients were categorized into 4 groups based on antibiotic administration: no change in antibiotics, deescalation, escalation (where antibiotics were changed to those with a broader spectrum of antimicrobial coverage), or mixed changes (where both escalation to a broader spectrum of coverage and discontinuation of antibiotics were carried out). …”
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A retrospective clinical study on the influencing factors of Clostridium difficile infection in elderly patients by Yang Chen, Yingjun Gong, Cui Li, Huan Li, Jia Chen, Hui Su, Xiaoming Wang, Xiaoxuan Ning

“…[Conclusion] The incidence of Clostridium difficile infection is negatively correlated with vitamin D, albumin and hemoglobin levels, and positively correlated with antibiotic use and serum creatinine level.The above indicators need to be closely monitored in elderly hospitalized patients.…”
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Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward? by Atul P. Kulkarni, Vasant C. Nagvekar, Balaji Veeraraghavan, Anup R. Warrier, Deepak TS, Jaishid Ahdal, Rishi Jain

“…Judicious prescription of antimicrobial agents, implementation of antibiotic stewardship programmes, and antibiotic policies in hospitals are essential to reduce the problem of drug-resistant infections in India. …”
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