A Challenging Case of Limb Salvage Requiring a Combination of Composite Fixation and Masquelet Technique to Address Significant Segmental Bone Loss by C. Blair, A. T. Simela, B. J. Cross

“…During the second stage of the procedure, the pseudomembrane is incised, the antibiotic spacer removed, and bone graft is placed. …”
Get full text

SEROTYPING AND ANTIMICROBIAL RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM DIARRHEIC CALVES IN THE PROVINCE OF TIZI-OUZOU, ALGERIA by Madjid Akkou, Madjid Sadi, Lamia Bentayeb, Yacine Titouche

“…The excessive use of antibiotics reduced their effectiveness, which eventually led to the risk of emergence of antibiotic resistance. …”
Get full text

Pattern of Bacterial Pathogens and Their Susceptibility Isolated from Surgical Site Infections at Selected Referral Hospitals, Addis Ababa, Ethiopia by Walelign Dessie, Gebru Mulugeta, Surafael Fentaw, Amete Mihret, Mulu Hassen, Engida Abebe

“…More than 58 (75%) of the Gram negative isolates showed multiple antibiotic resistance (resistance ≥ 5 drugs). Pan-antibiotic resistance was noted among 8 (34.8%) Acinetobacter species and 3 (12.5%) E. coli. …”
Get full text

Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review by Ioannis A. Ziogas, Alexandros P. Evangeliou, Olga Tsachouridou, Alexandra Arvanitaki, Afroditi Tsona, Vassilios Kamperidis, Marianthi Papagianni, Theofilos Panagiotidis, Ilias A. Tourtounis, George Giannakoulas, Symeon Metallidis

“…Timely diagnosis and antibiotic management are of paramount importance in order to avoid the potentially fatal sequelae.…”
Get full text

Complete genome sequencing and probiotic characterization of promising lactic acid bacterial strains isolated from dairy products in Egyptian markets by Mostafa F. El-Hosseny, Mohamed G Seadawy, Mohammed O Abdel-Monem, Mervat G Hassan

“…It may be beneficial to administer probiotic strains resistant to antibiotics concurrently with an antibiotic treatment. …”
Get full text

Comprehensive Analysis of <i>blaCTX-M1</i> Gene Expression Alongside <i>iutA</i>, <i>csgA</i>, and <i>kpsMII</i> Virulence Genes in Septicemic <i>Escherichia coli</i> Using Real-Ti... by Mohsen Karbalaei, Mojgan Esmailpour, Valentyn Oksenych, Majid Eslami

“…The key to treating these diseases is having sophisticated diagnostic tools and using antibiotics cautiously.…”
Get full text

Determination of In Vitro Antimicrobial Activity of Five Sri Lankan Medicinal Plants against Selected Human Pathogenic Bacteria by Manikkuwadura Hasara Nethmini De Zoysa, Hasanga Rathnayake, Ruwani Punyakanthi Hewawasam, Weerasinghe Mudiyanselage Dilip Gaya Bandara Wijayaratne

“…Introduction. Antibiotic resistance is one of the greatest threats of the 21st century. …”
Get full text

Antimicrobial Susceptibility Patterns of Shigella Species among Children under Five Years of Age with Diarrhea in Selected Health Centers, Addis Ababa, Ethiopia by Basha Ayele, Zeleke Mekonnen, Tesfaye Sisay Tessema, Etsehiwot Adamu, Estifanos Tsige, Getenet Beyene

“…The high levels of antibiotic resistance observed among the commonly prescribed antibiotics are alarming. …”
Get full text

Prevalence and Antimicrobial Resistance of Diarrheagenic Escherichia coli and Shigella Species Associated with Acute Diarrhea in Tehran, Iran by Fereshteh Jafari, Mohammad Hamidian, Maryam Rezadehbashi, Michael Doyle, Siavosh Salmanzadeh-ahrabi, Faramarz Derakhshan, Mohammad Reza Zali

“…The predominant E coli was Shiga toxin-producing E coli (105 isolates [34.5%]) and the predominant Shigella serotype was Shigella sonnei (88 isolates [56.1%]). A high rate of antibiotic resistance was observed among E coli, with 40 of 53 (75.5%) Shiga toxin-producing E coli isolates resistant to amoxicillin and tetra-cycline, and eight (5.2%) E coli isolates resistant to more than six antibiotics. …”
Get full text

Genome sequence and evaluation of safety and probiotic potential of Lacticaseibacillus paracasei LC86 and Lacticaseibacillus casei LC89 by Ting Chen, Yunjiao Zhao, Yunjiao Zhao, Yixuan Fan, Yao Dong, Zhonghui Gai

“…Secondly, whole-genome sequencing was performed on LC86 and LC89, and their antibiotic resistance, pathogenicity, and virulence genes were analyzed. …”
Get full text

Patient Perspectives on Evolving Diverticulitis Treatment: An Assessment of Patient Willingness to Enroll in a Randomized Controlled Trial by Annie Altman-Merino, MD, Kemberlee Bonnet, MA, David Schlundt, PhD, Jesse Wrenn, MD, PhD, Wesley H. Self, MD, MPH, Elisa J. Gordon, PhD, MPH, Alexander T. Hawkins, MD, MPH

“…The objective of the study was to assess patients’ attitudes regarding participation in a randomized trial of antibiotics versus placebo for acute diverticulitis. …”
Get full text

Antimicrobial Profiling of Bacteria Isolated from Fish Sold at Informal Market in Mufakose, Zimbabwe by Claudious Gufe, Tinashe Canaan Hodobo, Bernard Mbonjani, Otlia Majonga, Jerikias Marumure, Shuvai Musari, Gilbert Jongi, Pious Vengesayi Makaya, Jairus Machakwa

“…The number of infections caused by antibiotic resistant bacteria is rising worldwide. Fish from multisource pollution waters can harbour multidrug-resistant bacteria that can be disseminated to humans through eating or contact of contaminated fish. …”
Get full text

Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected... by Volker Mai, Maria Ukhanova, Lee Visone, Tamar Abuladze, Alexander Sulakvelidze

“…However, the significant weight loss detected in the control and antibiotic-treated groups was not observed in the infected, ListShield-treated mice. …”
Get full text

Multidrug-Resistant Escherichia coli Resulting in Postpartum Necrotizing Endomyometritis by Joan Tymon-Rosario, Meleen Chuang

“…After three weeks of antibiotic therapy, she had resolution of her infection. …”
Get full text

Microbes as Resources to Remove PPCPs and Improve Water Quality by Francesca Demaria, Marcel Suleiman, Philippe Corvini, Pilar Junier

“…These persistent pollutants can have negative effects on human health, ranging from antibiotic resistance development to endocrine disruption. …”
Get full text

Successful Treatment of High-Level Aminoglycoside-Resistant Enterococcus faecalis Bacteremia in a Preterm Infant with Ampicillin and Cefotaxime by Jennifer Tam, Santina J. Lee, Vibhuti Shah, Shaun K. Morris

“…Enterococcal bloodstream infections are usually treated with single-agent antibiotics. In persistent infections, synergistic combination therapy is often required with a beta-lactam and an aminoglycoside antibiotic. …”
Get full text

Characterization of Staphylococcus aureus Strains Isolated from Veterinary Hospital by Ariel E. Stella, Thaís F. Lima, Cecília N. Moreira, Eric M. N. De Paula

“…Methicillin resistance is determined by a chromosomal gene (mecA), which codes for modifications in the beta-lactam antibiotic receptor, where the penicillin-binding protein will have a low affinity for the antibiotic. …”
Get full text

Neglected adult PFAPA syndrome by Aiping Zhang, Ruifeng Zhang, Yiling Jiang, Ling Shi, Meihong Luo

“…Here we present a case of a 69-year-old woman with PFAPA syndrome, initially misdiagnosed as pharyngitis or lymphadenitis and received multiple antibiotic therapy without any clinical benefit. This report emphasizes the importance of early identification of the disease. …”
Get full text

Lymphomatoid granulomatosis. Case Presentation by Marisela García de la Torre, Yanelka Bouza Jiménez, Stephany Milagros Acosta País, Maribel Misa Menéndez

“…The case of a 21-year-old male patient is presented, who on December 30, 2017 began with increased volume, flushing and heat in the right lateral region of the neck, after the presence of a boil in the occipital region of the scalp. Treatment with antibiotic was started, but erythe-matopapular lesions appeared on the trunk and extremities that were interpreted as a medication adverse reaction. …”
Get full text

Antimicrobial Therapy as a Risk Factor of Multidrug-Resistant Acinetobacter Infection in COVID-19 Patients Admitted to the Intensive Care Unit by P. Mihalov, J. Hodosy, A. Koščálová, M. Čaprnda, M. Kachlíková, J. Jurenka, M. Bendžala, P. Sabaka

“…We assessed the role of prior antibiotic exposure and other factors as independent predictors of MDR-Ab isolation. …”
Get full text