The Treatment Effect of Plantago Major on Lung Cancer Based on the Computed Tomography and Pathological Findings: A Case Report Study by Saade Abdalkareem Jasim, Bashar Mudhaffar Abdullah, Patricio Yánez-Moretta, Wesam R. Kadhum, Yasser Fakri Mustafa, Enas R. Alwaily, Munther Abosoda, Ali Alsalamy, Sada Ghalib Al-Musawi, Alaa A. Omran

“…Conclusion: Based on our human study, PM, as a natural compound with antioxidant, anti-inflammatory, and antibiotic characteristics, could have an anti-proliferative effect on non-small cell lung cancer. …”
Get full text

Can Gut Microbiota Analysis Reveal <i>Clostridioides difficile</i> Infection? Evidence from an Italian Cohort at Disease Onset by Roberto Rosato, Gianluca Quaranta, Giulia Santarelli, Giovanni Fancello, Delia Mercedes Bianco, Francesca Romana Monzo, Stefano Bibbò, Giovanni Cammarota, Maurizio Sanguinetti, Luca Masucci, Flavio De Maio

“…<i>Clostridioides difficile</i> infection (CDI) is predominantly associated with the overuse of antibiotics, resulting in a significant alteration in the gut’s microbial balance. …”
Get full text

A quantitative PCR to detect non-toxigenic Clostridioides difficile by Khurshida Begum, Hubert C. Chua, M. Jahangir Alam, Kevin W. Garey, Jinhee Jo

“…Detecting these strains is critical as it underscores the importance of avoiding unnecessary antibiotic treatment in patients colonized with NTCD. …”
Get full text

Bacteraemia in a Nigerian hospital: Implementing antimicrobial resistance surveillance by Adewale A. Amupitan, Adeyemi T. Adeyemo, Adefunke O. Amupitan, Temitope O. Obadare, Aaron O. Aboderin

“…Bacterial identification, antibiotic susceptibility testing and detection of AMR genes followed standard protocols. …”
Get full text

Comparison of phenotypic and genetic traits of ESBL-producing UPEC strains causing recurrent or single episode UTI in postmenopausal women by Michelle Kalu, Peter Jorth, Annie Wong-Beringer

“…These results emphasize the potential microbial contributions to recurrence in postmenopausal women and warrant future investigations on the impact of antibiotic therapy and host response on IBC-supportive UPEC virulence.…”
Get full text

A systematic review on gut microbiota in type 2 diabetes mellitus by Serena Chong, Serena Chong, Mike Lin, Mike Lin, Deborah Chong, Slade Jensen, Slade Jensen, Slade Jensen, Namson S. Lau, Namson S. Lau, Namson S. Lau

Get full text

Methicillin-Resistant Staphylococcus aureus (MRSA): Prevalence and Antimicrobial Sensitivity Pattern among Patients—A Multicenter Study in Asmara, Eritrea by Eyob Yohaness Garoy, Yacob Berhane Gebreab, Oliver Okoth Achila, Daniel Goitom Tekeste, Robel Kesete, Robel Ghirmay, Ruta Kiflay, Thomas Tesfu

“…Isolates that are resistant to other tested antibiotics including vancomycin are also reported. …”
Get full text

Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile by Constanza Cárdenas, Paula Santana, Claudio Álvarez, Luis Mercado, Sergio Marshall, Fernando Albericio, Fanny Guzmán

“…One particularly relevant area is in drug discovery, offering alternatives to face the emergence of antibiotic-resistant microorganisms. Peptides are also prevalent in other sectors, such as the food industry, where they serve as food additives to enhance nutritional characteristics or aid in food preservation. …”
Get full text

Clostridium Scindens Protects Against Vancomycin‐Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR‐FGF15/19 Signaling by Jintao Xiao, Yanliang Hou, Xingyang Luo, Yuhao Zhu, Wenhu Li, Bingbing Li, LinXiang Zhou, Xia Chen, Ying Guo, Xiaomei Zhang, Haiyue He, Xiaowei Liu

“…Vancomycin, a glycopeptide antibiotic, has emerged as a promising candidate. However, the mechanism by which vancomycin impacts the progression of PSC remains unknown. …”
Get full text

Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae by Ye Huang, Yuan Huang, Zhiping Wu, Ziyue Fan, Fanglin Zheng, Yang Liu, Xinping Xu

“…Bacteriophages, also known as phages, are viruses that specifically infect bacteria; thus, phage-based therapies offer promising alternatives to antibiotic treatments targeting Hv-CRKp infections. …”
Get full text

Effectiveness of an electronic clinical decision support system in improving the management of childhood illness in primary care in rural Nigeria: an observational study by Marek Kwiatkowski, Rodolfo Rossi, Torsten Schmitz, Fenella Beynon, Capucine Musard, Marco Landi, Daniel Ishaya, Jeremiah Zira, Muazu Muazu, Camille Renner, Edwin Emmanuel, Solomon Gideon Bulus

“…Secondary outcomes were antibiotic and antimalarial prescription, referral, and communication of diagnosis and follow-up advice, assessed at day 0 exit interview.Results We recruited 1929 children, of which 1021 (53%) attended ALMANACH facilities, between March and September 2020. …”
Get full text

Establishment of a rapid and quantitative method for detecting the range of infection exposure in preclinical dental education by Ayaka Ueda, Yuki Shinoda-Ito, Kazu Takeuchi-Hatanaka, Takashi Ito, Shintaro Ono, Kimito Hirai, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba

“…The spread of infections such as SARS-CoV-2, antibiotic-resistant bacteria, and oral bacteria are sometimes lethal for medically compromised patients. …”
Get full text

Hexagonal zinc oxide nanoparticles: a novel approach to combat multidrug-resistant Enterococcus faecalis biofilms in feline urinary tract infections by Alaa H. Sewid, Alaa H. Sewid, Mohamed Sharaf, Mohamed Sharaf, Azza S. El-Demerdash, Sherif M. Ragab, Fatimah O. Al-Otibi, Mohamed Taha Yassin, Chen-Guang Liu

“…The synergistic effects of the combined formulation may offer a novel approach to overcome antibiotic resistance and improve the treatment outcomes of E. faecalis UTIs in domestic cats.…”
Get full text

Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…Conclusion Our meta-analysis suggests that PEDD is a potentially effective and safe intervention for SI. Optimizing antibiotic discontinuation and postoperative care strategies may contribute to reducing reoperation rate. …”
Get full text

Bearberry in the treatment of acute uncomplicated cystitis (BRUMI): protocol of a multicentre, randomised double-blind clinical trial by Péter Hegyi, Noémi Gede, Szilárd Váncsa, Barbara Tóth, András Jávorházy, Péter Nyirády, Boglárka Csupor-Löffler, Péter Birinyi, George Zhanel, Kurt Naber, Reinhard Länger, Nóra Vörhendi, Dezső Csupor

“…The antimicrobial activity of its extracts and some of its individual constituents has been observed in vitro; however, the efficacy of bearberry compared with standard antimicrobial therapy has not been assessed yet.Objective The objective of the study is to assess the safety and non-inferiority of bearberry as an alternative therapy in the treatment of acute uncomplicated cystitis in comparison with standard antibiotic therapy (fosfomycin).Methods and analysis This is a randomised controlled double-blinded multicentre trial. …”
Get full text

Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study by Ridhofar Akbar Khusnul Abdillah, Theresia Indah Budhy, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Muhammad Luthfi, Ninik Mas Ulfa, Albertus Putera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor, Alexander Patera Nugraha

“…Administering doxycycline may be the solution, but long-term side effects result in antibiotic resistance. Roselle flowers (Hibiscus sabdariffa) possess beneficial active phytochemical substances, which may have potential as an OMI peri-implantitis alternative therapy. …”
Get full text

Multiple viral infections and antimicrobial use in hospitalized children with respiratory illness during pandemic and early post-pandemic era, Taiwan by Chyi-Liang Chen, Yi-Ching Chen, Hsuan-Ling Hsiao, Yi-Jung Chang, Hsin-Chieh Li, Merve Arslan Aydin, Cheng-Hsun Chiu

“…Pediatric physicians continued to use antibiotics for febrile symptoms in hospitalized children with respiratory illness, even when viral pathogens were identified.…”
Get full text

Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

“…However, we encountered challenges that complicated pleural infection interpretation, including: (i) uncertainties regarding microbial pathogenicity and the impact of prior antibiotic therapy on diagnostic performance; (ii) lack of a clinical diagnostic gold-standard for molecular performance comparisons; (iii) potential microbial contamination during specimen collection or processing; and (iv) difficulties distinguishing background microbial noise from true microbial signal in low-biomass specimens. …”
Get full text

The MIL-125(Ti)/Co3O4 towards efficiently removing tetracycline by synergistic adsorption-photocatalysis roles by Qiuyang Dai, Guicheng Gao, Jijun Tang, Rongfei Jiang, Shijiao Sun, Yonglin Ye, Shiyun Li, Rong Xie, Jiaoxia Zhang

“…The efficient removal of antibiotic residues from water has become a significant concern in environmental management. …”
Get full text

Factors Predicting Ventilator Dependence in Patients with Ventilator-Associated Pneumonia by Chia-Cheng Tseng, Kuo-Tung Huang, Yung-Che Chen, Chin-Chou Wang, Shih-Feng Liu, Mei-Lien Tu, Yu-Hsiu Chung, Wen-Feng Fang, Meng-Chih Lin

“…Results from the Kaplan-Meier method indicate that initial therapy with antibiotics could increase the ventilator weaning rate (log Rank test, P<0.001). …”
Get full text