Assessment of Polypharmacy, Drug Use Patterns, and Associated Factors at the Edna Adan University Hospital, Hargeisa, Somaliland by Temesgen Sidamo, Alemu Deboch, Mohamed Abdi, Fikru Debebe, Khalid Dayib, Tamrat Balcha Balla

“…There was overuse of brand drugs (63.9%) and antibiotics (55.2%), while the use of injectables (19.9%) was within the acceptable range. …”
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Characterization of Carbapenem-Resistant Acinetobacter baumannii Strains Isolated from Hospitalized Patients in Palestine by Regeen Handal, Lulu Qunibi, Ibrahim Sahouri, Maha Juhari, Rula Dawodi, Hiyam Marzouqa, Musa Hindiyeh

“…All the isolates were resistant to all the β–lactam antibiotics including the carbapenems. Of the 69 isolates, 82.6% were positive for blaOXA-23, 14.5% were positive for blaOXA-24, and 3% were positive for blaOXA-58. …”
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High-Titre Neutralizing Antibodies to H1N1 Influenza Virus after Mouse Immunization with Yeast Expressed H1 Antigen: A Promising Influenza Vaccine Candidate by Edyta Kopera, Konrad Zdanowski, Karolina Uranowska, Piotr Kosson, Violetta Sączyńska, Katarzyna Florys, Bogusław Szewczyk

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Retropharyngeal Abscess in Adults: Five Case Reports and Review of the Literature by A. Harkani, R. Hassani, T. Ziad, L. Aderdour, H. Nouri, Y. Rochdi, A. Raji

“…The management of these cases is based on antibiotics and surgical drainage.…”
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Lemierre Syndrome with Extensive Thrombosis: A Unique Case Report and Literature Review by Stergos Koukias, Asimenia Athousaki, Dionisios Klonaris, Melina Kavousanaki, Georgios Papazoglou, Nikolaos Papanikolaou

“…Treatment included intravenous broad-spectrum antibiotics and anticoagulation therapy. Response to treatment was satisfactory. …”
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A Fatal Case of Septic Shock Secondary to Acinetobacter Bacteremia Acquired from a Platelet Transfusion by C. Nevala-Plagemann, P. Powers, M. Mir-Kasimov, R. Rose

“…Despite aggressive resuscitative efforts and appropriate antibiotics, the patient died approximately 48 hours following the transfusion reaction. …”
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Study of some virulence genes from uropathogenic Klebsiella pneumoniae and Pseudomonas aeruginosa isolated in Wasit Province, Iraq by Rana H. Raheema, Sabaa Hilal Hadi, Zainab Adil Ghani Chabuck

“…Abstract Background: Klebsiella pneumoniae and Pseudomonas aeruginosa are the most common causes of nosocomial urinary tract infections (UTIs), and in recent years, these bacteria have become significantly more resistant to antibiotics. Objective: The objective of the study was to determine the frequency of uropathogenic K. pneumoniae and P. aeruginosa in clinical urine samples from patients with UTIs in Wasit Province. …”
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Prevalence of Plasmid-Mediated Quinolone Resistance Determinants and OqxAB Efflux Pumps among Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae Isolated from Patients w... by Mehdi Goudarzi, Mehdi Azad, Sima Sadat Seyedjavadi

“…Given the linkage observed between resistance to quinolones and beta lactam antibiotics, therapeutic protocol with fluoroquinolones and beta lactam antibiotics should be seriously revised in Tehran hospitals.…”
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The genus Nocardia as a source of new antimicrobials by Napawit Nonthakaew, Liam K. R. Sharkey, Sacha J. Pidot

“…As a relatively underexplored genus, Nocardia represents a promising source for new antibiotics to combat the growing resistance crisis.…”
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Pneumonia due to a Rare Pathogen: Achromobacter xylosoxidans, Subspecies denitrificans by Hesham Awadh, Munthir Mansour, Obadah Aqtash, Yousef Shweihat

“…Diagnosis depends on cultures of appropriate specimens, and management usually is by administration of appropriate antibiotics (usually agents with antipseudomonal activity). …”
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A Multidimensional Approach to the Management of Severe Asthma: Inflammometry, Molecular Microbiology and Bronchial Thermoplasty by Conor Cox, Melanie Kjarsgaard, Michael G Surette, P Gerard Cox, Parameswaran Nair

“…Molecular microbiology and extended culture methods identified anaerobes and other airway microbiome that helped to guide the use of antibiotics. Further control of asthma was achieved by performing bronchial thermoplasty.…”
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Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Meningitis and Cerebral Abscess in a Neonate: Therapeutic Challenge by Surasak Puvabanditsin, Marianne Jacob, Maaz Jalil, Samhita Bhattarai, Qaiser Patel, Mehrin Sadiq, Rajeev Mehta

“…The patient received a 7-day course of antibiotics just few days prior to the infection. The incidence of infections from ESBL-producing E. coli is increasingly emerging. …”
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Scleredema Diabeticorum with Superimposed Cellulitis and Abscess Formation by Binav Shrestha, Eliza Sharma, Osama Mukhtar, Jaspreet Kaler, Shivani Thapa, Mazin Khalid

“…We present a case of an obese male with poorly controlled diabetes who came to the hospital with upper back pain and subsequently developed sepsis due to a small deep-seated abscess in his back that was drained and treated with antibiotics. He was also found to have extensive induration of the skin over his back and neck. …”
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A nursing and midwifery training program in Kathmandu on antimicrobial resistance and stewardship and infection prevention and control: a qualitative and quantitative outcomes and... by Jamuna Tamrakar Sayami, Rakchya Amatya, Kshitij Karki, Deepak Bajracharya, Basudha Shrestha, Sreenidhi Srinivasan, Tyler Prentiss, Anita Shallal, Marcus Zervos, Katie Latack, Linda Kaljee

“…Key outcomes were AMS and IPC knowledge, and decision-making about empirical dispensing of antibiotics. The process evaluation focused on training content, integration into practice, implementation barriers, and recommendations for dissemination. …”
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Necrotizing Fasciitis of the Nose Complicated with Cavernous Sinus Thrombosis by D. Swaminath, R. Narayanan, M. A. Orellana-Barrios, B. Temple

“…Treatment for septic cavernous sinus thrombosis is controversial but early use of empirical antibiotics is imperative.…”
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Ventricular Tachycardia from a Central Line Fracture Fragment Embolus: A Rare Complication of a Commonly Used Procedure—A Case Report and Review of the Relevant Literature by Saptarshi Biswas, Patrick McNerney

“…A 22-year-old male admitted with multiple gunshot wounds (GSW) had central line placed initially for hemodynamic monitoring and later for long term antibiotics and total parenteral nutrition (TPN). On postoperative day 4 he presented with bouts of nonsustained ventricular tachycardia; the cause was unknown initially and later attributed to a catheter fragment accidentally severed and lodged in the right heart. …”
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A Rare Twist of the Forgotten Disease: A Case of Fusobacterium necrophorum Sepsis with Portomesenteric Thrombosis and a Review of the Literature by Nicholas Lazar, Kamil Sardarli, Zaid Imam, Majd Khasawneh, Ismail Hader

“…We hereby report a case of pylephlebitis secondary to F. necrophorum bacteremia in a 57-year-old female originating from bacterial translocation secondary to colitis, who developed a favorable outcome with prompt treatment with antibiotics and anticoagulation. We also perform a literature review on similar cases in the literature and discuss management options of this rare but potentially fatal complication.…”
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Splenic Abscess after Sleeve Gastrectomy by Rany Aoun, Michel Gabriel, Elias El Haddad, Roger Noun, Ghassan Chakhtoura

“…The preferred treatment is either conservative, with intravenous antibiotics and percutaneous drainage, or splenectomy. …”
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Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis by Jeffrey R Schriber, John J Freedman, Joseph M Brandwein

“…The patient responded to therapy with plasmapheresis and antiplatelet agents as well as antibiotics. Coincident infection should be searched for in all cases of TTP.…”
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Abscess Formation after Septic Arthritis in the Sternoclavicular Joint of Two Healthy Men by Jeppe Henriksen, Mariann Tang, Vibeke Hjortdal

“…The abscesses were both treated surgically with debridement followed by negative pressure wound therapy and antibiotics. The cases differ in diagnostic procedures and delay of diagnosis and broach the issues of handling a rare disease.…”
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