Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii by Nicolas Flaugnatti, Loriane Bader, Mary Croisier-Coeytaux, Melanie Blokesch

“…This T6SS impairment is further enhanced when CPS is overproduced due to genetic modifications or antibiotic treatment. Furthermore, we demonstrate that the bacterium adjusts the level of the T6SS inner tube protein Hcp according to its secretion capacity, by initiating a degradation process involving the ClpXP protease. …”
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The role of the early-life gut microbiome in childhood asthma by Ulrika Boulund, Jonathan Thorsen, Urvish Trivedi, Kaare Tranæs, Jie Jiang, Shiraz A. Shah, Jakob Stokholm

“…These factors include cesarean birth, antibiotic use, breastfeeding, and having siblings or pets, among others. …”
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Bacterial Profile and Antimicrobial Susceptibility Pattern of the Isolates from Stethoscope, Thermometer, and Inanimate Surfaces of Mizan-Tepi University Teaching Hospital, Southwe... by Teshale Worku, Dejene Derseh, Abera Kumalo

“…The severity of infection depends on the characteristics of microorganisms with a high risk of being acquired when the environment is contaminated. Antibiotic-resistant bacteria are emerging rapidly around the globe creating a serious threat. …”
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Epidemiological Study of Hospital-Acquired Bacterial Conjunctivitis in a Level III Neonatal Unit by Catarina Dias, Márcia Gonçalves, Anabela João

“…Susceptibility patterns revealed bacterial resistances to several antibiotic classes. Gentamicin remains the adequate choice for empirical treatment of HAC in our NICU. …”
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Severe Wound Infection with Photobacterium damselae ssp. damselae and Vibrio harveyi, following a Laceration Injury in Marine Environment: A Case Report and Review of the Literatur... by Jörg Hundenborn, Steffi Thurig, Mechthild Kommerell, Heike Haag, Oliver Nolte

“…Management with daily wound dressing and antibiotic therapy (ofloxacin empirically, followed by doxycycline after availability of microbiology) led in the reported case to a favorable outcome, which seems to be, however, the exception based on a review of the available literature.…”
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Embolic risk management in infective endocarditis: predicting the ‘embolic roulette’ by Adela Mihaela Șerban, Diana Pepine, Andreea Inceu, Alexandra Dadarlat, Alexandru Achim

“…Therefore, future perspectives should focus on identifying high-risk profiles for EE and investigating whether early surgical intervention benefits these patients, even if they respond favourably to antibiotic therapy. This review explores current literature on echocardiographic and biomarker predictors of EE in IE, aiming to enhance clinical strategies for mitigating embolic complications and improving patient outcomes.…”
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Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease by Helen C. Steel, Riana Cockeran, Ronald Anderson, Charles Feldman

“…Notwithstanding the HIV pandemic, major challenges confronting the control of CAP include the range of bacterial and viral pathogens causing this condition, the ever-increasing problem of antibiotic resistance worldwide, and increased vulnerability associated with steadily aging populations in developed countries. …”
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Antimicrobial membranes based on polycaprolactone:pectin blends reinforced with zeolite faujasite for cloxacillin-controlled release by Bárbara Bernardi, João Otávio Donizette Malafatti, Ailton José Moreira, Andressa Cristina de Almeida Nascimento, Juliana Bruzaca Lima, Lilian Aparecida Fiorini Vermeersch, Elaine Cristina Paris

“…In this study, biopolymeric fibers based on polycaprolactone (PCL) and pectin (PEC) were reinforced with faujasite zeolite (FAU) for cloxacillin antibiotic (CLX) loading. FAU with a high specific surface area (347 ± 8 m2 g−1), high crystallinity and particles with a diameter of up to 100 nm were produced under optimized synthesis conditions (100 °C/4 h). …”
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mecA and PVL genes in methicillin-resistant Staphylococcus aureus from clinical specimens: a cross-sectional hospital based study from Nepal by Sirjana Adhikari, Supriya Sharma, Sanjib Adhikari, Sanjit Shrestha, Dwij Raj Bhatta

“…We aimed to determine the prevalence and antibiotic susceptibility pattern of MRSA isolated from patients attending a burn center and to detect mecA and PVL genes among MRSA isolates. …”
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Enhancement of the Antibacterial Efficiency of Silver Nanoparticles against Gram-Positive and Gram-Negative Bacteria Using Blue Laser Light by Anes Al-Sharqi, Kasing Apun, Micky Vincent, Devagi Kanakaraju, Lesley Maurice Bilung

“…Silver nanoparticles (Ag-NPs) possess excellent antibacterial properties and are considered to be an alternative material for treating antibiotic-resistant bacteria. The present study was aimed at enhancing the antibacterial efficiency of Ag-NPs using visible laser light against Escherichia coli and Staphylococcus aureus in vitro. …”
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Methotrexate Induced Pancytopenia by Fernando Gonzalez-Ibarra, Sahar Eivaz-Mohammadi, Shiri Surapaneni, Hazem Alsaadi, Amer K. Syed, Simon Badin, Valentin Marian, Mazhar Elamir

“…We present a case of a 73-year-old female with pancytopenia causing severe neutropenia, mucocutaneous bleeding, and bruising and requiring intravenous antibiotic therapy and limited transfusion dependence as a result of low dose daily MTX for rheumatoid arthritis.…”
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Efficacy and Tolerability of a Combined Moxifloxacin/Dexamethasone Formulation for Topical Prophylaxis in Phacoemulsification: An Open-Label Single-Arm Clinical Trial by Cesar Ramon G. Espiritu, Mary Ellen A. Sy, Tommee Lynne G. Tayengco

“…The use of a fixed-combination antibiotic corticosteroid for infection prophylaxis in Asian patients undergoing phacoemulsification has not been reported. …”
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The Bacterial Profile and Antimicrobial Susceptibility Patterns of Urinary Tract Infection Patients at Pawe General Hospital, Northwest Ethiopia by Abayeneh Girma, Aleka Aemiro

“…Rapidly increasing antibiotic resistance of uropathogens is resulting in limited treatment options. …”
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Fecal Microbiota Transplantation for Clostridioides Difficile Infection in Patients with Chronic Liver Disease by Alireza Meighani, Maryam Alimirah, Mayur Ramesh, Reena Salgia

“…Fecal microbiota transplantation (FMT) is a well-established therapeutic option for patients with antibiotic resistant Clostridioides difficile infection (CDI). …”
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Universal receptive system as a novel regulator of transcriptomic activity of Staphylococcus aureus by George Tetz, Kristina Kardava, Maria Vecherkovskaya, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Victor Tetz

“…Some of the genetic pathways were related to the inhibition of biofilm formation and increased antibiotic resistance, and we confirmed this at the phenotypic level using in vitro studies. …”
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Case Report: Pediatric pontine abscess and ecthyma gangrenosum due to Pseudomonas aeruginosa septicemia by Jonathan Theros, Madison Wolfe, Larry Kociolek, Larry Kociolek, Irini N. Kolaitis, Irini N. Kolaitis

“…He was initially treated with intravenous ceftazidime. Despite adequate antibiotic coverage he had persistent fevers. Whole-body magnetic resonance imaging revealed an expansile pontine mass; dedicated neuroimaging confirmed a 10 mm pontine abscess. …”
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A sterilization method for human decellularized vaginal matrices by Jayson Sueters, Leonie de Boer, Freek Groenman, Judith A. F. Huirne, Theo H. Smit, Sebastian A. J. Zaat

“…Based on our previously implemented decellularization technique with minor modifications, we designed and examined three sterilization methods consisting of (i) chemical decellularization, (ii) decellularization with additional peracetic acid/hydrogen peroxide (PAA/H2O2); (iii) decellularization with antibiotic and antimycotic (AAE) based treatment. Sterilization efficacy was evaluated through controlled contamination with common vaginal microbes and sterility testing subsequent to each sterilization method. …”
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The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis by Matteo Massara, Michelle Ballabio, Bastien Dolfi, Golnaz Morad, Vladimir Wischnewski, Eleni Lamprou, Joao Lourenco, Stéphanie Claudinot, Hector Gallart-Ayala, Rui Santalla Méndez, Annamaria Kauzlaric, Nadine Fournier, Ashish V. Damania, Matthew C. Wong, Julijana Ivanisevic, Nadim J. Ajami, Jennifer A. Wargo, Johanna A. Joyce

“…We thus evaluated the impact of antibiotics and BrM outgrowth on the gut-brain axis. …”
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Cytotoxicity towards human endothelial cells, induced by neutrophil myeloperoxidase: protection by ceftazidime by M. Mathy-Hartert, G. Deby-Dupont, C. Deby, L. Jadoul, A. Vandenberghe, M. Lamy

“…We investigated the effects of the antibiotic ceftazidime (CAZ) on the cytolytic action of the neutrophil myeloperoxidase–hydrogen peroxide–chloride anion system (MPO/H2O2/Cl−). …”
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Efficacy and safety of Saccharomyces boulardii as an adjuvant therapy for the eradication of Helicobacter pylori: a meta-analysis by Manning Li, Ying Xie

“…Current methods for eradicating H. pylori include triple or quadruple therapy, including antibiotics, proton pump inhibitors, and bismuth agents; however, with antibiotic abuse and increased drug resistance rates, the effectiveness of traditional methods is gradually decreasing, with many adverse effects such as abdominal pain, diarrhea, and intolerance. …”
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