Targeting the NOTCH2/ADAM10/TCF7L2 Axis‐Mediated Transcriptional Regulation of Wnt Pathway Suppresses Tumor Growth and Enhances Chemosensitivity in Colorectal Cancer by Zhen Xiang, Yiwei Wang, Xiao Ma, Shuzheng Song, Yuanqiao He, Jiamin Zhou, Longhai Feng, Su Yang, Yibin Wu, Bingran Yu, Guangkai Xia, Weiqi Xu, Yiming Zhao, Lu Wang

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CHARACTERISTICS OF CYTOPROTECTIVE EFFECT ON THE GASTRIC MUCOSA OF CRYOPRESERVED PLACENTA EXTRACT UNDER WATER-IMMOBILIZATION STRESS by Illia Koshurba, Fedir Hladkykh, Mykola Chyzh

“…Thus, NOS activity statistically significantly (p<0.001) decreased by 35.8%, and iNOS activity statistically significantly (p<0.001) decreased by 58.4% relative to the control animals. CEP under the prophylactic regimen showed more pronounced anti-ulcer activity than esomeprazole, which was 96.4% and 69.2%, respectively.…”
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100 essential questions for the future of agriculture by Yuming Hu, Taolan Zhao, Yafang Guo, Meng Wang, Kerstin Brachhold, Chengcai Chu, Andrew Hanson, Sachin Kumar, Rongcheng Lin, Wenjin Long, Ming Luo, Jian Feng Ma, Yansong Miao, Shaoping Nie, Yu Sheng, Weiming Shi, James Whelan, Qingyu Wu, Ziping Wu, Wei Xie, Yinong Yang, Chao Zhao, Lei Lei, Yong‐Guan Zhu, Qifa Zhang

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Generation of Insulin-Producing Cells from Canine Adipose Tissue-Derived Mesenchymal Stem Cells by Takahiro Teshima, Keiji Okamoto, Kazuho Dairaku, Tomokazu Nagashima, Masaki Michishita, Ryohei Suzuki, Hirotaka Matsumoto, Hidekazu Koyama

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Corrigendum: Notoginsenoside R1 protects against diabetic cardiomyopathy through activating estrogen receptor α and its downstream signaling by Bin Zhang, Bin Zhang, Bin Zhang, Bin Zhang, Jingyi Zhang, Jingyi Zhang, Jingyi Zhang, Jingyi Zhang, Chenyang Zhang, Chenyang Zhang, Chenyang Zhang, Chenyang Zhang, Xuelian Zhang, Xuelian Zhang, Xuelian Zhang, Xuelian Zhang, Jingxue Ye, Shihuan Kuang, Guibo Sun, Guibo Sun, Guibo Sun, Guibo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun

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Kefir Prevents Adipose Tissue Growth Through the Induction of Apoptotic Elements in High-Fructose Corn Syrup-Fed Rats by Esra Aslan, Gokhan Sadi, Hilal Guzel, Cigdem Karaca, Omer Adil Korkmaz, Mine Kanat Pektas, Mehmet Celegen, Tugce Aladag, Seyma Oncu, Mehmet Bilgehan Pektas

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Socio-economic assessment of drought impacts in Lesotho: implications for early action by Relebohile Agnes Mojaki, Makoala Vitalis Marake, Evan Easton-Calabria, Joalane Rethabile Marunye, Erin Coughlan de Perez

“…Drought-related impacts reported were: cost of food, prevalence of diarrhoea in children under five years of age, conflicts over resources, animal diseases and mortality, aridity and crop failure. …”
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Effect of Boiling on Colour, Contents of Betalains and Total Phenolics and on Antioxidant Activity of Colourful Powder Derived from Six Different Beetroot (Beta vulgaris L. var. co... by Jan Bárta, Veronika Bártová, Tereza Šindelková, Markéta Jarošová, Zuzana Linhartová, Jan Mráz, Jan Bedrníček, Pavel Smetana, Eva Samková, Ivana Laknerová

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Pengaruh Cairan Cultur Filtrate Fibroblast (CFF) Terhadap Penyembuhan Luka; Penelitian eksperimental pada Rattus Norvegicus Galur Wistar by Oky Masir, Menkher Manjas, Andani Eka Putra, Salmiah Agus

“…This study used an experimental design method post test only control group design and randomized block design (RBD) by using wistar mice. Experimental animals were divided into 4 groups, the two groups of treatment given to the area of excision wound CFF and the control group were given 0.9% NaCl solution to the excision wound area. …”
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The effectiveness of Lemna perpusilla as phytoremediation agent in giant gourami culture media on 3 ppt by Alexander Burhani Marda, Kukuh Nirmala, Enang Harris, Eddy Supriyono

“…Lemna perpusilla (duckweed) is prospective to use as an agent of phytoremediation of organic waste and can used as animal feed because it has high protein content. Meanwhile water salinity could be accelerate the growth of giant gourami. …”
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Transcriptome analysis reveals that PRV XJ delgE/gI/TK protects against intestinal damage in nose-dropping-infected mice by regulating ECM-ITGA/ITGB-P-FAK by Tong Xu, Yang Zhang, Qian Tao, Lei Xu, Si-Yuan Lai, Yan-Ru Ai, Jian-Bo Huang, Ben-Lu Yang, Ling Zhu, Zhi-Wen Xu

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Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma by Jie Mao, Shu-Ze Zhang, Peng Du, Zhi-Bin Cheng, Huan Hu, Shi-Yao Wang

“…To detect the tumor samples of 122 patients with colorectal carcinoma after surgery, analyze the effect of probiotics on enhancing tumor-infiltrating CD8+T cells to inhibit colorectal carcinoma, and further verify the mechanism of probiotics on enhancing the antitumor immune response of CD8+T cells through animal experiments. Results. The results of immunohistochemistry showed that the proportion of CD8+T cells in the patients treated with probiotics before surgery was increased significantly than that in other patients (P=0.033). …”
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Association of genomic predictions for fertility traits with reproductive outcomes in dairy cows under 2 estrus detection and timed artificial insemination programs by D.B. Melo, R.G.S. Bruno, R.S. Bisinotto, F.S. Lima

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AHP Approach To Developing a New Natural Toothpaste Product by Dikky Indrawan, Stevia Septiani, Galih Saputra Arista, Asep Rakhmat, Yessie W Sari, Nur A Nuzulia, Wulan T Wahyuni, Irmanida Batubara, Y. Aris Purwanto

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Uranium Mineral Transport in the Peña Blanca Desert: Dissolution or Fragmentation? Simulation in Sediment Column Systems by Victoria Pérez-Reyes, Rocio M. Cabral-Lares, Jesús G. Canche-Tello, Marusia Rentería-Villalobos, Guillermo González-Sánchez, Blanca P. Carmona-Lara, Cristina Hernández-Herrera, Fabián Faudoa-Gómez, Yair Rodríguez-Guerra, Gregorio Vázquez-Olvera, Jorge Carrillo-Flores, Ignacio A. Reyes-Cortés, Daniel Hernández-Cruz, René Loredo-Portales, María E. Montero-Cabrera

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Detection of antibodies against H5 subtype highly pathogenic avian influenza viruses in multiple raccoons in Tokachi District, Hokkaido, Japan, from 2022 to 2023 by Minami Komami, James G. Komu, Yuki Ishiguro, Motoki Sasaki, Sachiko Matsuda, Dulamjav Jamsransuren, Vuong Nghia Bui, Yohei Watanabe, Kunitoshi Imai, Haruko Ogawa, Yohei Takeda

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Eficiencia de uso del nitrógeno por forrajeras abonadas con estiércol de bovinos lecheros en la región pampeana, Argentina by M.A. HERRERO, V. CHARLÓN, L.I. CARBÓ, A. CUATRÍN, G.M.I. SARDI, L.1. ROMERO

“…La intensificación de los sistemas ganaderos con el consiguiente aumento de la carga animal incrementa la cantidad de estiércol que puede ser reutilizado como una fuente de nutrientes para cultivos forrajeros. …”
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Results of replacing fish meal with insect protein in carp feeds by O. Deren, O. Bernakevych, L. Bobeliak, N. Hrytsyshyna, M. Koryliak

“…The application of the knowledge gained in fish farming practice will provide an opportunity to replace traditional feed components with an alternative cheap, affordable and environmentally friendly source of animal protein.…”
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Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function... by Shan-Shan Zhao, De-Liang Tao, Jin-Ming Chen, Ming-Yi Zhang, Xin Yang, Jun-Ke Song, Qun Liu, Guang-Hui Zhao

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Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii by Wang M, Zeng Y, Liu M, Zhang D, Zhao D, Wang J, Liu Y, Zhao W

“…Developing an appropriate animal model will help further study the pathogenesis of CNGM.Methods: Seventy-two rats were randomly assigned to seven groups: group A (n=12, tissue suspension 0.2mL), group B (n=12, 1× 10^8 CFU/mL Corynebacterium kroppenstedtii (CK) suspension 0.1mL), group C (n=12, 1× 10^9 CFU/mL CK suspension 0.1mL), group D (n=12, tissue suspension 0.1mL + 1× 10^8 CFU/mL CK suspension 0.1mL), group E (n=12, tissue suspension 0.1mL + 1× 10^9 CFU/mL CK suspension 0.1mL), group F (n=6, phosphate buffer saline solution 0.1mL), and group G (n=6, physiological saline 0.1mL + Complete Freund’s adjuvant suspension 0.1mL). …”
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