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The evaluation of pharmacokinetic parameters of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide and its metabolites in rat plasma
Published 2024-12-01“…It is necessary to calculate the pharmacokinetic parameters of this compound and its metabolites in blood plasma of laboratory animals during a preclinical study. Aim: Evaluation of pharmacokinetic parameters of ODASA and its metabolites in rat bloodplasma after instillation of ocular suspension and its intraperitoneal administration. …”
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Curcumin administration alleviates seminal vesicle damage in type 1 diabetic rats by promoting AQP8 expression through AR activation
Published 2025-01-01“…This study revealed that (1) seminal vesicle volume and seminal fluid secretion were reduced in diabetic rats and (2) ultrasonography can predict seminal vesicle secretory dysfunction in diabetic rats, providing a theoretical basis for selecting animal models of diabetic seminal vesicle dysfunction for subsequent studies. …”
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12403
Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet
Published 2025-02-01“…These results highlight potential mechanistic explanations and therapeutic targets for addressing sex differences and underscore the need to study both sexes in animal models and human MASH.…”
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12404
Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia
Published 2025-01-01“…Using a chronic unpredictable mild stress (CUMS) combined with multi-platform water environment sleep deprivation (SD) as an animal model, the occurrence and development of human depression combined with insomnia were simulated. …”
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12405
EyeLiner
Published 2025-03-01“…Results: EyeLiner effectively aligns longitudinal image pairs from FIRE, SIGF, and CORIS, as qualitatively evaluated through registration checkerboards and flicker animations. Quantitative results show that the MD decreased for this model after alignment from 321.32 to 3.74 pixels for FIRE, 9.86 to 2.03 pixels for CORIS, and 25.23 to 5.94 pixels for SIGF. …”
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12406
Enhancing surveillance for dengue fever in Oyo State, Nigeria – a one health approach
Published 2025-01-01“…Abstract Background Dengue fever (DF) poses a growing global threat, necessitating a comprehensive one-health approach to address its complex interplay between human, animal, and environmental factors. In Oyo State, Nigeria, the true burden of DF remains unknown due to underdiagnosis and misdiagnosis as malaria, exacerbated by poor health-seeking behavior, weak surveillance systems, and inadequate health infrastructure. …”
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Vaccines in the fight against antimicrobial resistance – perspectives from South Africa
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Detection and characterization of bovine hepacivirus in cattle and sheep from Hulunbuir, northeastern China
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Multiomics identify the gene expression signature of the spinal cord during aging process
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12413
Une gestion plurielle des illégalismes : négociations et contradictions dans la régulation des eaux usées au Maroc
Published 2022-12-01“…Thus, the moqqadems are structurally inclined to forbearance because of two main factors : their daily confrontation with users’ capacities of resistance, which dissuades them from repressing too harshly ; and their homology of subaltern position with the latter, which makes them sensitive to the moral economy of subsistence that animates the farmers. However, this posture of indulgence only heightens tensions with other State actors. …”
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Testicular biometrics of Murrah buffaloes in different age groups
Published 2023-11-01“…In addition, it was estimated that, for each kilogram of live weight that the animal gains, the SC grows 0.05 ± 0.00 cm (p<0.01) and TV 0.42 ± 0.1 cm3 (p<0.01). …”
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Disponibilidad de biomasa y contenido de proteína cruda de cuatro especies de pasto asociadas con Leucaena leucocephala cultivar Cunninghan en sistema de pasturas en callejones
Published 2024-11-01“…La disponibilidad de biomasa con alto contenido de proteína es esencial en la nutrición animal, la que puede ser obtenida combinando especies de pasto con leguminosas forrajeras. …”
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Differentiations in Illness Duration, Thyroid-Stimulating Hormone, Glucose and P300 Latency Between Drug-Naïve Unipolar and Bipolar Depression: A Comparative Cross-Sectional S...
Published 2025-01-01“…Chao Li,1,2 Lei Yang,1,2 Qiuyu Zhang,1,2 Ying Zhang,1,2 Ranli Li,1,2 Feng Jia,1,2 Lina Wang,1,2 Xiaoyan Ma,1,2 Kaifang Yao,1,2 Hongjun Tian,3,* Zengxun Liu,4,* Chuanjun Zhuo1,2,* 1Computational Biology and Animal Imaging Center (CBAC), Tianjin Anding Hospital, Nankai University Affiliated Tianjin Anding Hospital, Tianjin Medical University Affiliated Tianjin Anding Hospital, Tianjin Medical University Affiliated Tianjin Mental Health Center, Tianjin, 300222, People’s Republic of China; 2Laboratory of Psychiatric-Neuroimaging-Genetic and Co-morbidity (PNGC_Lab), Tianjin Anding Hospital, Tianjin Mental Health Center of Tianjin Medical University, Tianjin, 300222, People’s Republic of China; 3Department of Psychiatry, Tianjin Fourth Center Hospital, Nankai University Affiliated Tianjin Fourth Center Hospital, Tianjin, 300140, People’s Republic of China; 4Department of Psychiatry, Shandong Mental Health Center, Jinan, 250014, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuanjun Zhuo, Tianjin Anding Hospital, Nankai University Affiliated Tianjin Anding Hospital, Tianjin Medical University Affiliated Tianjin Anding Hospital, Tianjin Medical University Affiliated Tianjin Mental Health Center, Tianjin, 300222, People’s Republic of China, Tel/Fax +86-22-24394542, Email chuanjunzhuotjmh@163.comBackground: Distinguishing bipolar depression (BD) from unipolar depression (UD) remains a major clinical challenge, especially in drug-naïve patients. …”
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