Retrovirus Entry by Endocytosis and Cathepsin Proteases by Yoshinao Kubo, Hideki Hayashi, Toshifumi Matsuyama, Hironori Sato, Naoki Yamamoto

“…Retroviruses include infectious agents inducing severe diseases in humans and animals. In addition, retroviruses are widely used as tools to transfer genes of interest to target cells. …”
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IL-10 in Antilipopolysaccharide Immunity Against Systemic Klebsiella Infections by Tomislav Rukavina, Brigita Ticac, Vanja Vasiljev

“…The ratios between IL-10 and proinflammatory cytokines confirmed the suppressed proinflammatory response in protected animals, especially 24 hours postinfection. Hence the mortality in unprotected mice begins immediately after we conclude that such cytokine relation and IL-10 production are, at least partially, responsible for the destiny of infected animals and the outcome of infection.…”
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Effect of Multiple Stresses (Thermal, Nutritional, and Walking Stress) on the Reproductive Performance of Malpura Ewes by V. Sejian, V. P. Maurya, K. Kumar, S. M. K. Naqvi

“…The ewes were randomly allocated into two groups of twelve animals each namely, GI (𝑛=12; Control), and GII (𝑛=12; Multiple stresses). …”
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Metabolic Context Regulates Distinct Hypothalamic Transcriptional Responses to Antiaging Interventions by Alexis M. Stranahan, Bronwen Martin, Wayne Chadwick, Sung-Soo Park, Liyun Wang, Kevin G. Becker, William H. WoodIII, Yongqing Zhang, Stuart Maudsley

“…In this paper, we investigated the effects of two well-characterized antiaging interventions, caloric restriction and voluntary wheel running, in two distinct physiological paradigms, that is, diabetic (db/db) and nondiabetic wild-type (C57/Bl/6) animals to investigate the contextual sensitivity of hypothalamic transcriptomic responses. …”
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Sympathoexcitation Associated with Renin-Angiotensin System in Metabolic Syndrome by Takuya Kishi, Yoshitaka Hirooka

“…As a novel aspect connecting the importance of SNS and RAS activation, we and other investigators have recently demonstrated that angiotensin II type 1 receptor (AT1R) blockers (ARBs) improve SNS activation in patients with MetS. In the animal studies, SNS activation is regulated by the AT1R-induced oxidative stress in the brain. …”
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Effects of Selected Antioxidants on Electroretinography in Rodent Diabetic Retinopathy by Radosław Dutczak, Marita Pietrucha-Dutczak

“…Since numerous studies are based on animal models, validating the ERG results from animals is pivotal. …”
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Characteristics of the intestinal tract microbiota in calves with various forms of acute catarrhal bronchopneumonia by N. Yu. Rodionova, E. V. Kulikov, E. D. Sotnikova, I. E. Prozorovskiy, Yu. A. Vatnikov, V. B. Rudenko, P. A. Rudenko

“…The samples taken from clinically healthy animals (n = 8) were used as controls. It has been shown that in calves with compensated acute catarrhal bronchopneumonia, the qualitative and quantitative composition of the intestinal microbiome does not differ from clinically healthy animals. …”
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Adipose-Derived Stem Cells Are an Efficient Treatment for Fistula-in-ano of Japanese Rabbit by Xiao Qin, Peng Wang, Yongming Huang, Yansen Li, Min Chao, Wei Wang

“…The rabbit is an effective animal model for evaluating FIA therapeutic options.…”
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Advanced In Vitro Models for Preclinical Drug Safety: Recent Progress and Prospects by Dileep G. Nair, Ralf Weiskirchen

“…Traditionally, identifying DILI risk has been difficult due to the poor correlation between preclinical animal models and in vitro systems. Differences in physiology between humans and animals or cell lines contribute to the failure of many drug programs during clinical trials. …”
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Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent by V. A. Graham, G. J. Hatch, K. R. Bewley, K. Steeds, A. Lansley, S. R. Bate, S. G. P. Funnell

“…New vaccines against biodefense-related and emerging pathogens are being prepared for licensure using the US Federal Drug Administration’s “Animal Rule.” This allows licensure of drugs and vaccines using protection data generated in animal models. …”
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Is the BCG Vaccine Safe for Undernourished Individuals? by Larissa Lumi Watanabe Ishikawa, Larissa Camargo da Rosa, Thais Graziela Donegá França, Raphael Sanches Peres, Fernanda Chiuso-Minicucci, Sofia Fernanda Gonçalves Zorzella-Pezavento, Alexandrina Sartori

“…In addition, only undernourished animals had bacteria in the lungs and thymus. Concomitant with higher mycobacterial loads and more widespread BCG dissemination in undernourished mice, production of TNF-α, IFN-γ, and IL-10 was also diminished in these mice. …”
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Mouse Thyroid Gland Changes in Aging: Implication of Galectin-3 and Sphingomyelinase by Giovanna Traina, Samuela Cataldi, Paola Siccu, Elisabetta Loreti, Ivana Ferri, Angelo Sidoni, Michela Codini, Chiara Gizzi, Marzia Sichetti, Francesco Saverio Ambesi-Impiombato, Tommaso Beccari, Francesco Curcio, Elisabetta Albi

“…Importantly, in comparison with the thyroid of young animals, we have found a higher expression of galectin-3 and a delocalization of neutral sphingomyelinase in the thyroid of old animals. …”
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Serological Survey and Factors Associated with Toxoplasma gondii Infection in Domestic Goats in Myanmar by Saw Bawm, Wint Yi Maung, Myat Yee Win, May June Thu, Hla Myet Chel, Tin Aye Khaing, Soe Soe Wai, Lat Lat Htun, Tin Tin Myaing, Saruda Tiwananthagorn, Makoto Igarashi, Ken Katakura

“…With the occurrence value obtained in this first study, a second one, more complete, with larger number (162) of animals and properties, was carried out and the risk factors and prevalence were determined. …”
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Use of p30,pK205R and pB602L recombinant proteins for African swine fever serodiagnosis by M. R. Yakupov, A. S. Yakovleva, A. V. Scherbakov

“…The sensitivity рЗО-ELIS A and pK205R-ELIS A used for testing sera from experimentally and naturally infected animals was found to be higher than that one of commercial test systems and comparable to the ELISA recommended by the World Animal Health Organization for ASF serological diagnosis. …”
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Mechanism of Human Tooth Eruption: Review Article Including a New Theory for Future Studies on the Eruption Process by Inger Kjær

“…The aetiology or the mechanism behind eruption has never been fully understood and the scientific literature in the field is extremely sparse. Human and animal tissues provide different possibilities for eruption analyses, briefly discussed in the introduction. …”
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TESTING OF COMBINED VACCINES AGAINST AUJEZSKY’S DISEASE, PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME AND PORCINE PARVOVIRUS INFECTION FOR THEIR ANTIGENICITY by Ye. P. Baborenko, Ye. K. Dolganova, K. N. Gruzdev

“…The use of the vaccine based on marker Aujeszky’s disease virus strain allows differentiation between the animals that have antibodies to the marker vaccine strain (in the absence of antibodies to the glycoprotein gE in 100% of cases) from the animals with antibodies to field strains of the Aujeszky’s disease virus in their sera. …”
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The Discovery of Novel Experimental Therapies for Inflammatory Arthritis by Charles J. Malemud

“…Indeed several experimental compounds alter the biological activity of these targets and have shown clinical efficacy in animal models of arthritis. A few of them have even entered the first phase of human clinical trials.…”
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Qu’est-ce qu’une « race animale pure » ? by Patricia Pellegrini, Marie-Dominique Ribereau-Gayon

“…In France, studies on farm animal breeding in various disciplines (anthropology, sociology, history, zootechny, etc.) extensively use the notion of “race”. …”
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A Case Report of Monkeypox in a 4-Year-Old Boy from the DR Congo: Challenges of Diagnosis and Management by Anna Korsgaard Eltvedt, Michael Christiansen, Anja Poulsen

“…Furthermore, closer contact between humans and bush animals could play a role along with the ongoing difficulties of controlling HIV in the same geographical area. …”
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Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus by Garrick Salois, Jeffrey S. Smith

“…Furthermore, the most complex astrocytes were significantly more complex among animals housed in EE compared to standard environments.…”
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