Neurotoxic Dorsal CA1 Lesions versus 4 VO Ischaemic Lesions: Behavioural Comparisons by J. A. Nunn, J. A. Gray, H. Hodges

“…Together with the greater behavioural deficits of ischaemic rats, these data indicate a role for extra-CA1 cell loss in ischaemia-induced memory impairments in both animals and humans.…”
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Paired Stimulation to Promote Lasting Augmentation of Corticospinal Circuits by Noam Y. Harel, Jason B. Carmel

“…This review addresses what is known about paired stimulation of the corticospinal system of both humans and animal models, emphasizes how it qualitatively differs from single-site stimulation, and discusses the gaps in knowledge that must be addressed to maximize its use and efficacy in neurorehabilitation.…”
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CathROB: A Highly Compact and Versatile Remote Catheter Navigation System by Laura Cercenelli, Barbara Bortolani, Emanuela Marcelli

“…We report in vitro and in vivo animal evaluation of CathROB. In vitro results showed good accuracy in remote catheter navigation and automatic repositioning (1.5 ± 0.6 mm for the left-side targets, 1.7 ± 0.4 mm for the right-side targets). …”
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Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review by Lei Lu, Ying Jiang, Ravindran Jaganathan, Yanli Hao

“…Recently, advancements in pluripotent stem cells technology enable restoration of retinal functionalities after transplantation of these cells into animals with retinal degeneration. This review paper summarizes the developments in the current and potential pharmacotherapy and therapeutic technology of DR. …”
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Evaluation of GABAergic Transmission Modulation as a Novel Functional Target for Management of Multiple Sclerosis: Exploring Inhibitory Effect of GABA on Glutamate-Mediated Excitot... by Ankit A. Gilani, Ranjeet Prasad Dash, Mehul N. Jivrajani, Sandeep Kumar Thakur, Manish Nivsarkar

“…In this study, sodium valproate was found to show the best activity in the animal models whereas phenobarbitone sodium showed moderate activity. …”
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Differential Expression of Motilin Receptor in Various Parts of Gastrointestinal Tract in Dogs by Yu He, Hui Wang, DongYan Yang, ChengYan Wang, LanLan Yang, Chunxiang Jin

“…The presence of motilin receptor in the GI tract of different animal species has been verified. However, the quantitation of motilin receptor expression in different regions of the GI tract remains unclear. …”
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Patient-Specific Pluripotent Stem Cells in Neurological Diseases by Serpen Durnaoglu, Sermin Genc, Kursad Genc

“…However, iPSC-based therapeutic strategies need to be thoroughly evaluated in preclinical animal models of neurological diseases before they can be applied in a clinical setting.…”
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Use of Autologous Mesenchymal Stem Cells Derived from Bone Marrow for the Treatment of Naturally Injured Spinal Cord in Dogs by Euler Moraes Penha, Cássio Santana Meira, Elisalva Teixeira Guimarães, Marcus Vinícius Pinheiro Mendonça, Faye Alice Gravely, Cláudia Maria Bahia Pinheiro, Taiana Maria Bahia Pinheiro, Stella Maria Barrouin-Melo, Ricardo Ribeiro-dos-Santos, Milena Botelho Pereira Soares

“…Cell suspensions were prepared and surgically administered into the spinal cord. The animals were clinically evaluated and examined by nuclear magnetic resonance. …”
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Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut by Mehari Endale, H. Ibrahim Aksoylar, Kasper Hoebe

“…In addition, the generation of “IBD-prone” animal models using both reverse and forward genetic approaches has not only helped confirm the identification of susceptibility loci but also shed critical insight into the underlying molecular and cellular pathways that drive colitis development. …”
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Precision nanoparticles for drug delivery, cell therapy tracking, and theranostics by Felder-Flesch, Delphine, Talamini, Laura, Muller, Sylviane

“…Certain dangers or fears regarding their use in human and animal therapy or for users have been mentioned. Finally, conclusions and future perspectives are provided.…”
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Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…Our results showed that ALPP transgenic mice are more susceptible to intraperitoneal injection of LPS in comparison to control animals. In addition, female ALPP transgenic mice were better at delaying the rejection of male skin grafts. …”
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PCL/PHBV Microparticles as Innovative Carriers for Oral Controlled Release of Manidipine Dihydrochloride by Fernanda Malaquias Barboza, Willian Moreira Machado, Luiz Renato Olchanheski Junior, Josiane Padilha de Paula, Sônia Faria Zawadzki, Daniel Fernandes, Paulo Vitor Farago

“…In vitro dissolution studies showed that all microparticles prolonged MAN release, mainly which one obtained using PCL that contained 5% of drug loaded (PCL-M5). Animal studies demonstrated that formulation PCL-M5 was able to keep the variation of mean arterial pressure after phenylephrine administration up to 24 hours. …”
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The Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Anterior Segment by Menglei Wang, Meixuan Li, Pisong Yan, Qiang Luo, Yu Zhang, Zhiyu Du

“…The right corneas of 36 New Zealand rabbits were treated with HIFU keratoplasty. The animals were sacrificed at 1, 7, 15, 30, 60, and 90 days after operation. …”
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Facultative parthenogenesis: a transient state in transitions between sex and obligate asexuality in stick insects? by Larose, Chloé, Lavanchy, Guillaume, Freitas, Susana, Parker, Darren J., Schwander, Tanja

“…Such a trade-off could help explain why facultative parthenogenesis is rare among animals, despite its potential to combine the known benefits of sex and parthenogenesis. …”
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Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in db/db Mice Using Cytokine Antibody Array by Xue Mei Fan, Chun Lian Huang, Yi Ming Wang, Ning Li, Qiong Lin Liang, Guo An Luo

“…The following study investigates the adjustment mechanism of Tangshen formula (TSF) on cytokine expressions in db/db mice (DN animal model). Materials and Methods. Db/db mice were randomly divided into three groups. …”
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Impact of Chlorella vulgaris and probiotic supplementation on performance, immunity and intestinal microbiota of broiler chickens. by Verena Pereira Dinalli, Marcio Carvalho Costa, Emerson José Venâncio, João Antônio Barbosa Filho, José Antônio Bessegatto, Augusto Tasch Holkem, Amauri Alcindo Alfieri, Caio Abercio da Silva, Alexandre Oba

“…Bifidobacterium spp. was found in animals receiving 1% microalgae and probiotics on day 42, suggesting that this genus has benefited from microalgae supplementation. …”
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Stability and neurotoxic impact of organophosphate pesticides in aqueous environments by Vladan J. Anićijević, Tamara Tasić, Vedran Milanković, Radovan M. Karkalić, Tamara D. Lazarević Pašti

“…Their acute toxicity is ascribed to inhibiting acetylcholinesterase (AChE), a key enzyme in the transmission of nerve impulses in animals. Their toxic effects manifest by acetylcholine accumulation in the nerve synapses and can lead to paralysis or death. …”
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Evaluation of the Association Metformin: Plantago ovata Husk in Diabetic Rabbits by Raquel Díez-Láiz, Juan J. García-Vieitez, M. José Diez-Liébana, Matilde Sierra-Vega, Ana M. Sahagún-Prieto, Ángela P. Calle-Pardo, Nélida Fernández-Martínez

“…Insulin pharmacokinetics parameters after treatment with oral metformin showed an important increase in Cmax, AUC, and tmax in animals fed with fiber. We conclude that Plantago ovata husk intake can contribute to the oral antihyperglycemic treatment of type 2 diabetes.…”
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Germination and establishment of Teramnus labialis (L.f.) Spreng plants are affected by scarification treatment used by Yanier Acosta, Sershen, Jorge A. Sánchez, Inaudis Cejas, Dayamí Fontes, Marcos E. Martínez-Montero

“… Background: Some of the species that make up the legume family are used as animal feed and to improve soil fertility. However, their use is limited due to low seed availability and low germination rates. …”
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OCCURRENCE OF LUMPY SKIN DISEASE IN CATTLE IN THE WORLD by V. P. Semakina, M. V. Zhiltsova, A. V. Savvin, T. P. Akimova

“…Virus is transmitted through skin, mucous membranes of respiratory, digestive organs and conjunctiva, then it enters into the lymph nodes where it replicates, and then it is transported along the body with blood. Animals excrete the virus with expired air, saliva, semen, milk, nasal and ocular discharges, and exudates. …”
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