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  1. 681

    Study on static characteristics of a novel prestress-reinforced railway subgrade by Junli Dong, Fang Xu, Qishu Zhang, Wuming Leng, Yafeng Li, Qi Yang

    Published 2024-08-01
    “…Abstract Understanding the reinforcement effect of the newly developed prestressed reinforcement components (PRCs) (a system composed of prestressed steel bars (PSBs), protective sleeves, lateral pressure plates (LPPs), and anchoring elements) is technically significant for the rational design of prestressed subgrade. …”
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  2. 682
  3. 683

    Like objects or like subjects? Effects of student–robot interaction (SRI) and mathematical ability on students learning outcomes by Segun Michael Ojetunde, Umesh Ramnarain

    Published 2025-01-01
    “…This constitutes the major reason why the study investigated the effects of student–robot interaction and mathematical ability on students' learning outcomes, particularly among Nigerian high school students where the robotics curriculum is at the early stage of implementation. The study was anchored on engagement theory. A mixed-methods explanatory sequential Quant-dominant approach was adopted. …”
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  4. 684

    Hip Arthroscopy for Femoroacetabular Impingement Syndrome: Preoperative Radiographic Findings and Risk Factors for Reoperation at 3–6 Years Postoperatively by Andrea H. Johnson, Laura A. Stock, Jane C. Brennan, Justin J. Turcotte, Benjamin M. Petre

    Published 2023-01-01
    “…Patients who underwent a subsequent THA were significantly older (P < 0.001) and required more suture anchors for repair (P < 0.001) than those that did not. …”
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  5. 685

    Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. by Rana Zakerzade, Ching-Ho Chang, Kamalakar Chatla, Ananya Krishnapura, Samuel P Appiah, Jacki Zhang, Robert L Unckless, Justin P Blumenstiel, Doris Bachtrog, Kevin H-C Wei

    Published 2025-01-01
    “…Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where central elements are connected on two sides by the transverse filaments to the chromatin-anchoring lateral elements. Despite being found in most major eukaryotic taxa implying a deeply conserved evolutionary origin, several components of the complex exhibit unusually high rates of sequence turnover. …”
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  6. 686

    Inhibition of hippocampal interleukin-6 receptor-evoked signalling normalises long-term potentiation in dystrophin-deficient mdx mice by Kimberley A. Stephenson, Aaron Barron, Mark G. Rae, Dervla O'Malley

    Published 2025-02-01
    “…In non-contracting cells, such as neurons, dystrophin is likely to have a functional role in synaptic plasticity, anchoring post-synaptic receptors. Dystrophin-expressing hippocampal neurons are key to cognitive functions such as emotions, learning and the consolidation of memories. …”
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  7. 687

    The Content-Validated Geometry Lessons in Islam Observed Brain-based Learning by Sherma O. Sappari, Florante P. Ibarra, Amirul Mukminin, Kasinyo Harto, Lenny Marzulina, Herri Mulyono, Asmendri Asmendri

    Published 2023-11-01
    “… This study examined the process of learning geometry in content-validated lessons with the integration of Islamic values as perceived to have observed brain-based learning principles. Anchored in a grounded theory, theoretical sampling was utilized among sixteen 4th and 5th grade students in geometry class including three teacher-observers and one teacher-demonstrator playing the “emic-etic” role or participant observer. …”
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  8. 688

    From Silos to Synergy: Conceptualizing an integrated infrastructure design for climate resilience in Rotterdam by Angela Ordóñez Llancce, Yirang Lim, Theresa Audrey O. Esteban, Joep van Leeuwen, Johan Ninan

    Published 2025-01-01
    “…In recent years, municipalities have been recognised for their crucial role in protecting cities from climate change impacts by adopting mitigative and adaptive strategies to enhance climate resilience. However, anchoring these strategies demands multiple interventions, which are often hindered by the current siloed organization of departments and disciplines. …”
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  9. 689

    Molecular genetic basis of epidermolysis bullosa by Yu. Yu. Kotalevskaya, V. A. Stepanov

    Published 2023-03-01
    “…To date, pathogenic variants in 16 different genes are associated with EB and encode proteins that are part of the skin anchoring structures or are signaling proteins. Genetic mutations cause dysfunction of cellular structures, differentiation, proliferation and apoptosis of cells, leading to mechanical instability of the skin. …”
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  10. 690

    Barriers and facilitators to implementation of non-medical independent prescribing in primary care in the UK: a qualitative systematic review by Nicola Carey, Judith Edwards, Melaine Coward

    Published 2022-06-01
    “…The Diffusion of Innovations and Consolidated Framework for Implementation Research were guiding theoretical anchors.Primary and secondary outcome measures N/A.Results Twenty-three articles addressing nurse, pharmacist and physiotherapist IP were included. …”
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  11. 691

    Entanglement negativity and replica symmetry breaking in general holographic states by Xi Dong, Jonah Kudler-Flam, Pratik Rath

    Published 2025-01-01
    “…For k < 1, which includes the case of E $$ \mathcal{E} $$ (A : B) at k = 1/2, we use a modified cosmic brane proposal to derive a new holographic prescription for E 2 k $$ {\mathcal{E}}^{(2k)} $$ and show that it is given by a new saddle with multiple cosmic branes anchored to subregions A and B in the original state. …”
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  12. 692

    Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. by Athos Silva De Oliveira, Leroy Versteeg, Neima Briggs, Rakesh Adhikari, Maria Jose Villar, JeAnna R Redd, Peter Hotez, Maria Elena Bottazzi, Jeroen Pollet

    Published 2025-01-01
    “…<h4>Methodology/findings</h4>By leveraging the flexible design of RNA vaccines and protein intracellular trafficking signal sequences, we developed three variants of Na-GST-1 as native (cytosolic), secretory, and plasma membrane-anchored (PM) antigens. After one immunization in mice, mRNA vaccines induced an earlier onset of antigen-specific antibodies compared to rNa-GST-1. …”
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  13. 693

    Empagliflozin Reverses Oxidized LDL-Induced RECK Suppression, Cardiotrophin-1 Expression, MMP Activation, and Human Aortic Smooth Muscle Cell Proliferation and Migration by Bysani Chandrasekar, Srinivas Mummidi, Vincent G. DeMarco, Yusuke Higashi

    Published 2023-01-01
    “…Reversion-inducing cysteine-rich protein with Kazal motifs (RECK) is a membrane-anchored MMP inhibitor. Empagliflozin is an SGLT2 inhibitor and exerts pleiotropic cardiovascular protective effects, including antioxidant and anti-inflammatory effects. …”
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  14. 694

    Emyooga Programme and Job Creation in Kabale District Uganda. by Niwasasira, Saviour

    Published 2024
    “…The study was guided by specific objectives which included: assessing the extent to which the Emyooga programme has contributed to job creation in Kabale District; examining the relationship between governance structures in the Emyooga programme and job creation in Kabale District; establishing the relationship between the capacity-building mechanisms in the Emyooga programme and job creation in Kabale District; and, to evaluate the relationship between infrastructure framework in the Emyooga programme and job creation in Kabale District. The study was anchored on the“Theory of Change” whose roots are traced back to the 1990s. …”
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  15. 695

    Examining reliability of WHOBARS: a tool to measure the quality of administration of WHO surgical safety checklist using generalisability theory with surgical teams from three New... by Jennifer M Weller, Carmen Skilton, Derryn A Gargiulo, Oleg N Medvedev, Simon J Mitchell, Alan F Merry

    Published 2019-01-01
    “…Objectives To extend reliability of WHO Behaviourally Anchored Rating Scale (WHOBARS) to measure the quality of WHO Surgical Safety Checklist administration using generalisability theory. …”
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  16. 696

    Guest-Host Interactions in Symmetrical Carboxy Heptamethine Cyanine Dyes-Titanium Dioxide Systems: Synthesis, Theoretical Calculations, Aggregation Properties, and Application in D... by Rodrigo da Costa Duarte, Matheus Costa de Oliveira, Josene Maria Toldo, Paulo Fernando Bruno Gonçalves, Marcos José Leite Santos, Fabiano Severo Rodembusch

    Published 2021-01-01
    “…Heptamethine cyanines containing carboxylic anchoring groups were obtained with good yields. The cyanines present UV-Vis absorption in methanol and dimethylformamide solutions ascribed to fully allowed electronic transitions (1ππ∗), as well as fluorescence emission in the NIR region, with any evidence of aggregations in both ground and excited states. …”
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  17. 697

    Akt/p27kip1 Pathway Is Not Involved in Human Insulinoma Tumorigenesis by Adriana Graciela Díaz, Andrea Paes de Lima, Paula Garibaldi, Maria de los Milagros Rubio, Florencia García, Marta Kral, Oscar D. Bruno

    Published 2018-01-01
    “…Cytoplasmic p27kip1 in both insulinomas and normal islet cells could reflect the low rate of replication of beta cells, while nuclear p27kip1 would seem to indicate stabilization and nuclear anchoring of the cyclin D-Cdk4 complex. Our data seem to suggest that the Akt pathway is not involved in human insulinoma tumorigenesis.…”
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  18. 698

    Observations of Loki Patera by Juno during Close Flybys by Alessandro Mura, Rosaly M. C. Lopes, Federico Tosi, Francesca Zambon, Roberto Sordini, Peter J. Mouginis-Mark, Julie Rathbun, Scott Bolton, Jani Radebaugh, Alberto Adriani, Andrea Cicchetti, Davide Grassi, Melissa Mirino, Raffaella Noschese, Giuseppe Piccioni, Christina Plainaki, Giuseppe Sindoni

    Published 2025-01-01
    “…The persistence of these islands challenges resurfacing models of Loki, as they have remained fixed—likely anchored to the lava lake floor—and have not noticeably changed in size, arguing against large-scale thermal erosion. …”
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  19. 699

    An assessment of the progress made in the implementation of the regional framework for cholera prevention and control in the WHO African region by Miriam Nanyunja, Allan Mpairwe, Ibrahim Mamadu, Otim Patrick Cossy Ramadan, Mory Keïta, Tamayi Mlanda, Abdou Salam Gueye, Ebenezer Obi Daniel, Etien Luc Koua, Dick Chamla, Fiona Braka, Fred Kapaya, Vincent Dossou Sodjinou, Godwin Akpan, Shikanga O-tipo, Amarachi Tikal Abianuru, John Masina, Alice Igale Ladu, Fred Athanasius Dratibi, Philippe Barboza

    Published 2025-01-01
    “…Effective implementation of the cholera prevention and control framework anchored on strong government commitment and ownership is essential to curb the current trend of cholera outbreaks and improve the likelihood of cholera elimination by 2030 in Africa.…”
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  20. 700

    PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) DENGAN HYPERCOAGULABLE STATE by Fitrach Desfiyanda, Irza Wahid

    Published 2018-07-01
    “…Hal ini disebabkan oleh kelainan seluler karena mutasi somatik pada hematopoetic stem cell yang menyebabkan terjadinya defisiensi berbagai jenis protein yang diperlukan bagi pembentukan glycosylphosphatidylinositol (GPI) anchored, yakni antara lain yang tersering decay accelerating factor (DAF, CD55) dan membrane inhibitor of reactive lysis (MIRL, CD59). …”
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