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70661
Evolution of Green Technology, Technology Gap and International Trade A Comparative Study of Developing and Developed Countries
Published 2024-12-01“…The data used in this analysis spans during 2008 - 2019 and is sourced from UNCTAD and WORLD BANK. …”
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70662
IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3
Published 2025-02-01“…HT1080 and 4T1 cells treated with IFNβ were subjected to RNA-Seq analysis. STAT1, STAT3, TRIM21, and TRIM22 were silenced by siRNAs to examine their effects on IFNβ-induced ferroptosis. …”
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70663
Assessing microbial biodiversity in oil palm seedlings using oil palm waste compost mixed media
Published 2024-10-01“…Method: The study compared microbial biodiversity in soil media with compost amendments by employing DNA sequencing to assess microbial communities. The analysis focused on bacterial species richness and the prevalence of key phyla, including Proteobacteria, Actinobacteria, Acidobacteria, and others. …”
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70664
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease
Published 2025-02-01“…Network pharmacology identified the PRKAA2 (AMPK) and SIRT1 as key hub targets. Futher analysis of their structures using AlphaFold3 algorithms, yielded high-ranking scores of 0.97 and 0.93, respectively. …”
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70665
Infrared illumination for difficult peripheral venous catheterisation in critically ill adult patients: the prospective, randomised, multicentre ICARE trial
Published 2025-02-01“…Our hypothesis is that infrared vein illumination could improve the success rate of peripheral venous catheterisation in critically ill patients at risk of difficult catheterisation.Methods and analysis This is a prospective, multicentre, randomised, open-label controlled trial. …”
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70666
Treatment failure and drug resistance among the newly reported HIV-infected patients in Taizhou City from 2020 to 2022
Published 2024-11-01“…Multivariate logistic regression analysis was used to analyze the influencing factors of treatment failure. …”
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70667
The protective effects of Levilactobacillus brevis FZU0713 on lipid metabolism and intestinal microbiota in hyperlipidemic rats
Published 2023-09-01“…Furthermore, liver metabolomics analysis demonstrated that L. brevis FZU0713 had a significant regulatory effect on the composition of liver metabolites in hyperlipidemic rats, especially the levels of some important biomarkers involved in the metabolic pathways of arachidonic acid metabolism, primary bile acid biosynthesis, amino sugar and nucleotide sugar metabolism, taurine and hypotaurine metabolism, biosynthesis of unsaturated fatty acid, fructose and mannose metabolism, tyrosine metabolism, etc. …”
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70668
Sustainability assessment of animal feed production from by-products of Sago palm smallholder industry
Published 2024-07-01“…Sustainability status and leverage attributes were analyzed by Monte Carlo analysis and alternating least-squares algorithm.FINDINGS: The results showed that the general sustainability indicators in Sago palm smallholder industry had an average value of 46.03 percent. …”
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70669
25 años de cirugía de Ross: seguimiento y resultados en pacientes reoperados en nuestro centro
Published 2025-01-01“…Their characteristics and survival were studied using Kaplan-Meier analysis. Results: The mean follow-up of the patients undergoing RR was 17.5 ± 5 years (median 19 years, range 0-25 years). …”
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70670
Effect of Simultaneous Use of Different Amounts of Biochar and Soil Application of Common Sulfur and Spraying of Nanosulfur on Yield and Yield Components and Some Phytochemical Cha...
Published 2025-09-01“…The data were analyzed using composite analysis. Different biochar levels (5, 10, and 20 t.ha⁻¹, plus a control) and sulfur nutritional treatments (common sulfur, nano-sulfur, and control) were assigned to the main and subplots, respectively.Results and Discussion The results of this study showed that the highest and lowest seed number per m2 and flowering shoot weight were obtained in treatments of 20 t.ha-1 biochar and spraying of nanosulfur (with 27777 seeds per m2 and 25.67 g flowering shoot, respectively) and non-application of biochar and control (with 8024 seeds per m2 and 6.24 g flowering shoot, respectively). …”
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70671
Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF...
Published 2025-01-01“…The molecular function of transmembrane proline‐rich Gla proteins (PRRGs) remains unexplored. Methods Analysis of pancreatic ductal adenocarcinoma (PDAC) datasets, including transcription profiles, clinical data, and tissue microarrays, was conducted to evaluate PRRG1 expression and its clinical relevance. …”
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70672
Genomic insights into population dynamics and adaptive strategies of the endangered dipterocarp, Hopea chinensis
Published 2025-01-01“…Furthermore, selective sweep analysis showed 12 genes associated with cold and drought tolerance and plant defense and immunity. …”
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70673
Anti-Inflammatory Potential and Synergic Activities of <i>Eclipta prostrata</i> (L.) L. Leaf-Derived Ointment Formulation in Combination with the Non-Steroidal Anti-Inflammatory Dr...
Published 2024-12-01“…The plant extract was used to make a cream formulation for treating atopic dermatitis and as an antibacterial agent against <i>Staphylococcus aures</i>, the major infectious agent associated with AD. The phytochemical analysis of the <i>E. prostrata</i> extract showed the presence of various phytochemicals, including flavonoids, Tannin, saponin, terpenoids, glycosides, phenol, alkaloids, quinone, and protein. …”
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70674
FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma
Published 2025-02-01“…Accordingly, in vitro and in vivo studies have confirmed the inhibitory role of FAM210B on the growth and tumor metastasis of LUAD cells. RNA-seq analysis further indicated that FAM210B plays a role in regulating innate immune-related signaling pathways in LUAD cells, particularly involving the production of type I interferon (IFN-α/β). …”
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70675
A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
Published 2021-01-01“…These observations were confirmed at the protein level for HepG2 and DLD-1 cells grafted on a chorioallantoic membrane. Cell-cycle analysis showed a complete loss of proliferating cells with a simultaneous increase in S-phase arrest beginning at a threshold dose of 30 μM. …”
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70676
SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer
Published 2025-03-01“…Mechanistically, we observed that in chemoresistant breast cancer cell lines, SLC31A1 knockdown resulted in a substantial decrease in the expression of carnitine palmitoyltransferase 1A (CPT1A), a rate-limiting enzyme of fatty acid oxidation (FAO). RNA-Seq analysis indicated that FAO might be implicated in SLC31A1-mediated breast cancer progression. …”
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70677
An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept studyResearch in context
Published 2025-02-01“…Key features for identifying agitation included low nocturnal respiratory rate, heightened alertness during sleep, and increased indoor illuminance, as revealed by statistical and feature importance analysis. Using our interactive tool, we identified indoor lighting and temperature adjustments as the most promising and feasible intervention options within our cohort. …”
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70678
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
Published 2021-02-01“…These findings were validated by flow cytometric analysis of both mouse (LLC-OVA, MC38 and B16-OVA) and human (NSCLC and melanoma) tumor samples. …”
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70679
Effects of water flow treatment on muscle quality, nutrient composition and volatile compounds in common carp (Cyprinus carpio)
Published 2025-02-01“…Conversely, SG showed elevated ∑EPA + DHA and ω-3 fatty acid levels compared to IG. Volatile compound analysis demonstrated that CG contained higher levels of aldehydes and alcohols, associated with off-flavors, whereas IG and SG produced fresher and sweeter aroma profiles, enhancing sensory quality. …”
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70680
An Overview of Solar Orbiter Observations of Interplanetary Shocks in Solar Cycle 25
Published 2025-01-01“…Finally, we give details and guidance on the access use of the present survey, available on the EU-project “Solar Energetic Particle Analysis Platform for the Inner Heliosphere” website. …”
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