L’aqueduc du Gier : nouvelles données sur le pont-siphon de Beaunant à Sainte-Foy-lès-Lyon (Métropole de Lyon) by David Baldassari, François Blondel, Stéphane Gaillot

“…The presence of this masonry structure suggests that in Antiquity the main channels of the river probably passed between the piers at the bottom of the eastern slope of the valley.Beyond this indication of the old route of the river, the geoarchaeological approach also provides matter for discussion on the possible causes of the collapse of the bridge, which probably involved one or more consecutive or associated factors: weaknesses in the subsoil, the influence of meteorological factors or natural disasters.The data acquired during this excavation contribute significantly to ideas about the techniques and architectural choices that governed the construction of the bridge, together with more general thinking about the dating of a hydraulic structure as important as the Gier aqueduct, which is of not insignificant impact for the analysis of the urban development of the Roman colony of Lugdunum.…”
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USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer by Fang Yuan, Juan Xu, Lingmei Xuan, Chan Deng, Wei Wang, Rong Yang

“…Finally, we looked into the biological processes linked to USP14 using gene set enrichment analysis (GSEA), which was later verified. Results: We observed a significant upregulation of USP14 in human ESCA tissues and cell lines, especially in those with radioresistance. …”
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Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018 by Bouchez-Zacria, Malika, Calenge, Clément, Villers, Alexandre, Lecollinet, Sylvie, Gonzalez, Gaelle, Quintard, Benoit, Leclerc, Antoine, Baurier, Florence, Paty, Marie-Claire, Faure, Éva, Eraud, Cyril, Decors, Anouk

“…In addition, common blackbird populations could be monitored through another network (REZOP). Statistical analysis (spatial, temporal, spatiotemporal and environmental determinants) of the SAGIR and AFVPZ network data helped to highlight the early appearance of separate large clusters of USUV cases in mid-July 2018, the subsequent diffusion into smaller and secondary clusters at the end of August 2018, and a meanwhile enlargement of the first clusters with an increase in the number of cases. …”
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The Adaptation, Implementation, and Performance Evaluation of Intake24, a Digital 24-h Dietary Recall Tool for South Asian Populations: The South Asia Biobank by Divya Bhagtani, Birdem Amoutzopoulos, Toni Steer, David Collins, Suzanna Abraham, Bridget A Holmes, Baldeesh K Rai, Rajendra Pradeepa, Sara Mahmood, Abu Ahmed Shamim, Poorvee Mathur, Lathika Athauda, Laksara De Silva, Khadija I Khawaja, Vinitaa Jha, Anuradhani Kasturiratne, Prasad Katulanda, Malay K Mridha, Ranjit M Anjana, John C Chambers, Polly Page, Nita G Forouhi

“…Conclusions: Intake24 enables comprehensive dietary assessment in regions of South Asia and will facilitate the analysis of dietary patterns, food and nutrient intake, and their relationship with health outcomes among South Asians.…”
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Description of global innovative methods in developing the WHO Community Engagement Package by Jackeline Alger, Don Mathanga, Semeeh Akinwale Omoleke, Noel Juban, Meredith Labarda, Obinna Ikechukwu Ekwunife, Obioma Nwaorgu, Allan Ulitin, Jana Deborah Mier-Alpaño, María Isabel Echavarría, Yolanda Vargas Bayugo, Jose Rene Bagani Cruz, Pauline Marie Padilla Tiangco, Ukam Ebe Oyene, Alberto Ong Jr, Marvinson See Fajardo, Barwani Khaura Msiska, Lorena Abella Lizcano, Natalia Gomez Quenguan, Claudia Ivette Nieto Anderson, Briana Yasmin Beltran, Elsy Denia Carcamo Rodriguez, Eduardo Salomón Núñez, Vera Nkosi-Kholimeliwa, Glory Mwafulirwa-Kabaghe

“…Interviews with CE practitioners were also conducted.Results A total of 356 cases were found to fit the inclusion criteria and proceeded to data extraction and thematic analysis. Themes were organised according to rationale, key points and insights, facilitators of CE and barriers to CE. …”
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Psychological counselling interventions to improve perceived quality of life and counter anxiety and depression in pulmonary-arterial-hypertension patients: A clinical trial by Emilia TARANTINO, Pietro CRESCENZO, Maria CAMPOBASSO, Francesca D’ALESSANDRO, Paola ARGIENTO, Emanuele ROMEO, Stefano GHIO, Patrizio VITULO, Francesco PARISI, Massimiliano MULÈ, Carlo ALBERA, Carmine Dario VIZZA, Michele D’ALTO

“…However, between pre- and post-session evaluations, the analysis showed a significant change in the EQ-VAS score (P = 0.00) and the anxiety/depression dimension (P = 0.02) in the EG. …”
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Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome by Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng

“…MA displayed similar therapeutic effects but had less pronounced effects on GnRH axons. Transcriptome analysis revealed distinct mechanisms for these two approaches: EA primarily regulates neuroglial plasticity, whereas MA predominantly targets neurotransmitter regulation. …”
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Ultrasound and histopathological assessment of benign, borderline, and malignant thyroid tumors in pediatric patients: an illustrative review and literature overview by Dominika Januś, Dominika Januś, Monika Kujdowicz, Monika Kujdowicz, Aleksandra Kiszka-Wiłkojć, Aleksandra Kiszka-Wiłkojć, Konrad Kaleta, Anna Taczanowska-Niemczuk, Anna Taczanowska-Niemczuk, Jan Radliński, Kamil Możdżeń, Zuzanna Nowak, Wojciech Górecki, Wojciech Górecki, Jerzy B. Starzyk, Jerzy B. Starzyk

“…However, given that not all solid thyroid nodules are malignant, a more conservative approach may also be appropriate in certain cases.ObjectiveThis study aims to present an illustrative analysis of the pathological foundations underlying the sonographic appearance of benign, borderline, and malignant thyroid nodules in the pediatric population at a single tertiary thyroid center.MethodsA total of 47 well-documented pediatric patients referred for thyroid surgery between 2010 and 2023 were analyzed. …”
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Knowledge, attitude, and perception of Pakistani populations toward monkeypox: a cross-section study by Humayun Yousaf, Abdul Qadeer, Muhammad Sohail, Maqbool Khan, Muhammad Farooq, Zakir Khan, Dalia Fouad, Yu-Chia Liu, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen

“…Statistical analyses were performed in Jupyter Notebook using Python 3 and the Pandas, Matplotlib, and stats libraries.ResultsThe chi-square test and regression analysis evaluated factors related to Mpox knowledge, attitude, and perception of three thousand four hundred sixty-five participants. …”
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Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor by Ke Sun, Yong-Li Wang, Chen-Chen Hou, Da Shang, Lin-Juan Du, Lan Bai, Xing-Yu Zhang, Chuan-Ming Hao, Sheng-Zhong Duan

“…Consistently, BP in Ang II-infused KO mice decreased significantly to the similar level as those in LC mice after amiloride treatment. ChIP analysis revealed that NCOR1 deficiency increased the enrichment of mineralocorticoid receptor (MR) on the promoters of the three ENaC genes in primary inner medulla collecting duct (IMCD) cells. …”
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Pengaruh Hiperglikemia terhadap Gambaran Histopatologis Pulau Langerhans Mencit by Muhammad Farid, Eryati Darwin, Delmi Sulastri

“…The objective of this study was to determine the effect of hyperglycemia on histopathological features of islet of Langerhans, we examined pancreatic tissues from 24 male Swiss Albino mice: 6 control (K) and 18 glucose-treated mice with 3 different doses (G1=2g/kg, G2=4g/kg, G3=6g/kg) for 14 days to induce hyperglycemia. Morphometric analysis of islet of Langerhans on H&E-stained pancreatic sections showed that the islet area and diameter were increased in group G1 (48607.13 μm2 and 240713.25 nm, respectively; p<0.01) but decreased in group G2 (5471.42 μm2 and 81170.83 nm, p<0.01) and G3 (4628.07 μm2 and 74730.86 nm, p<0.05). …”
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Indocyanine Green Fluorescence Plus Blue Dye for Sentinel Lymph Node Biopsy in Patients Undergoing Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter, Prospective Cohort Stu... by Miao Liu, Yang Yang, Bin Hua, Rui Feng, Tianyu Xu, Mengyuan Wang, Xiaowei Qi, Yingming Cao, Bo Zhou, Fuzhong Tong, Peng Liu, Hongjun Liu, Lin Cheng, Houpu Yang, Fei Xie, Siyuan Wang, Chaobin Wang, Yuan Peng, Danhua Shen, Lei Chen, Jun Jiang, Shu Wang

“…Negative predictive value was 95.7% (88/92; 95% CI, 89.4%–98.3%). In the subgroup analysis stratified by ycN status, FNR was 4.0% (1/25; 95% CI, 0.7%–19.5%) and 8.6% (3/35; 95% CI, 3.0%–22.4%) in the ycN0 and ycN+ subgroups, respectively. …”
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Delta radiomics modeling based on CTP for predicting hemorrhagic transformation after intravenous thrombolysis in acute cerebral infarction: an 8-year retrospective pilot study by Xiaxia Wu, Xiaxia Wu, Jinfang Yang, Jinfang Yang, Xianqun Ji, Yingjian Ye, Ping Song, Lina Song, Peng An, Peng An

“…., age, sex, NIHSS score, medical history) to establish various models for predicting HT-ACI through multivariable logistic regression analysis. The predictive performance of the models was compared using DeLong curves, clinical net benefit was assessed using decision curves, and model predictions were validated using the XGboost algorithm. …”
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A Mixed Project-and-Stock Portfolio Optimization Model with Mean-SemiVariance-SemiEntropy Approach by Amirhosein Khayyatian, Majid Shakhsi-Niaei

“…By incorporating project investments alongside traditional stocks, the proposed model offers more efficient portfolios that can lead to improved return/risk ratios for investors seeking to optimize their overall financial strategy.Design/methodology/approach: An attempt has been made to bridge the gap between the distinct spaces of projects and stocks to facilitate their joint analysis. Subsequently, a Mean-SemiVariance-SemiEntropy approach has been employed to develop a model within a probabilistic framework. …”
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Identification of as a Susceptibility Locus for Kawasaki Disease in Patients Younger than 6 Months of Age by Hea-Ji Kim, Sin Weon Yun, Jeong Jin Yu, Kyung Lim Yoon, Kyung-Yil Lee, Hong-Ryang Kil, Gi Beom Kim, Myung-Ki Han, Min Seob Song, Hyoung Doo Lee, Kee Soo Ha, Sejung Sohn, Ryota Ebata, Hiromichi Hamada, Hiroyuki Suzuki, Yoichiro Kamatani, Michiaki Kubo, Kaoru Ito, Yoshihiro Onouchi, Young Mi Hong, Gi Young Jang, Jong-Keuk Lee

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Impact of Nutritional Support for Tuberculosis on Intermediate and Terminal Undernutrition and Treatment Outcomes (INSTITUT) study: a protocol for a quasi-experimental study to ass... by Dissou Affolabi, Chelsie Cintron, Madolyn Dauphinais, Attannon Arnauld Fiogbe, Mohammed Fall Dogo, Safiou Ate, Christine Adjonou, Kokou Agossou, Susie Jiaxing Pan, Marius Esse, Benjamin Ade, Komi Séraphin Adjoh, Pranay Sinha, Kobto G Koura

“…Comparing treatment outcomes of PWTB treated in Benin and Togo can help us understand the impact of nutritional support for PWTB.Methods and analysis We designed a programmatic, prospective cohort study to assess the treatment outcomes among persons with pulmonary tuberculosis under programmatic conditions. …”
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Noninvasive Evaluation of Liver Fibrosis in a Sample of Putative Inactive HBV Carriers in Rome, Italy by Marco Delle Monache, Alessio Petrelli, Alessandra Rossi, Roberto Cecere, Concetta Mirisola, Gianfranco Costanzo, Chiara Francia, Federica Cerini, Andrea Cavani, Lorenzo Nosotti

“…Patients with HBV-DNA <2000 IU/ml had a significantly lower LS than those with HBV-DNA ≥2000 IU/ml (5.30 ± 1.43 vs. 7.69 ± 1.07, p<0.0001). Conclusions. Analysis shows lower effectiveness of FS vs. TE in the assessment of putative inactive HBV carriers. …”
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Evaluation of eco-driving performance of electric vehicles using driving behavior-enabled graph spectrums: A naturalistic driving study in China by Hui Zhang, Yiyue Luo, Naikan Ding, Toshiyuki Yamamoto, Chenming Fan, Chunhui Yang, Wei Xu, Chaozhong Wu

“…After the six drivers with the highest and lowest ecological assessment of driving behavior using the behavior graph and energy consumption graph, proposing the quantitative analysis of fifteen drivers' ecology driving behavior. …”
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Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+ by Zhian Chen, Tianhua Zhou, Zhengbo Yin, Peiya Duan, Ying Zhang, Yujiao Feng, Rongmao Shi, Yongqing Xu, Rongqing Pang, Hongbo Tan

“…Cartilage damage was detected by gross observation, micro-CT, and histological analysis. The expression levels of related genes were detected by real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR). …”
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Pengaruh Pemberian Kopi Instan Oral Terhadap Kadar Asam Urat pada Tikus Wistar by Fauzan Arisyi Koto, Husnil Kadri, Zelly Dia Rofinda

“…One way Anova dan Post hoc tests analysis showed significant differences of uric acid levels only between control and treatment 2 group and between treatment 1 group and treatment 2 group (p&lt;0,05). …”
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