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  1. 70241
  2. 70242

    LRP1 involvement in FHIT-regulated HER2 signaling in non-small cell lung cancer by Théophile Ponchel, Emma Loeffler, Julien Ancel, Audrey Brisebarre, Nathalie Lalun, Véronique Dalstein, Anne Durlach, Gaëtan Deslée, Stéphane Dedieu, Myriam Polette, Béatrice Nawrocki-Raby

    Published 2025-03-01
    “…Here, we sought to decipher the FHIT-regulated HER2 signaling pathway in NSCLC. Transcriptomic analysis of tumor cells isolated from NSCLC revealed the endocytic receptor low density lipoprotein receptor-related protein 1 (LRP1), a central regulator of membrane trafficking and cell signaling, as a potential player of this signaling. …”
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  3. 70243

    Ibero-American consensus statement on migraine treatment by José Miguel Láinez, Oscar Pradilla, Pablo Irimia, Fidel Sobrino, Michel Volcy, Pedro Kowaks, Ildefonso Rodríguez Leyva, Fiorella Martín, Lucía Zavala, Alex Espinoza

    Published 2025-01-01
    “…The objective of this document is to establish a consensus position on the pharmacological treatment of migraine, including general measures and detailed analysis of the different options for the treatment of attacks and their prevention, from the perspective of Ibero-American countries. …”
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  4. 70244

    Digital Platforms’ Adoption by Educational Stakeholders in Private Secondary Schools During and after the Lockdown in Port Harcourt Local Government Area, Rivers State by Ella Gogo Blaise, Ebi Bio Awotua-Efebo

    Published 2024-12-01
    “…To collect data, three distinct questionnaires and an observation checklist were administered. The data analysis was done using frequency, ranking, and bar charts. …”
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    Article
  5. 70245

    Establishing a radiomics model using contrast-enhanced ultrasound for preoperative prediction of neoplastic gallbladder polyps exceeding 10 mm by Dong Jiang, Yi Qian, Yijun Gu, Ru Wang, Hua Yu, Zhenmeng Wang, Hui Dong, Dongyu Chen, Yan Chen, Haozheng Jiang, Yiran Li

    Published 2025-02-01
    “…Radiomics with CEUS is a powerful tool for analysis of GBP > 10 mm. The model not only improves diagnostic accuracy and reduces healthcare costs but also optimizes patient management through personalized treatment plans, enhancing clinical outcomes and ensuring resources are more precisely allocated to patients who need surgery.…”
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  6. 70246

    Impact of surgical site infection (SSI) following gynaecological cancer surgery in the UK: a trainee-led multicentre audit and service evaluation by Rachel L O’Donnell, Georgios Angelopoulos, James P Beirne, Ioannis Biliatis, Helen Bolton, Melissa Bradbury, Elaine Craig, Ketan Gajjar, Michelle L Mackintosh, Wendy MacNab, Thumuluru Kavitha Madhuri, Mark McComiskey, Eva Myriokefalitaki, Claire L Newton, Nithya Ratnavelu, Sian E Taylor, Amudha Thangavelu, Sarah A Rhodes, Emma J Crosbie, Richard J Edmondson, Yee-Loi Louise Wan

    Published 2019-01-01
    “…A clinical diagnosis of SSI was made in 54 (16%) women. 33% (18/54) of women with SSI had prolonged hospital stays, and 11/37 (29%) had their adjuvant treatment delayed or cancelled. Multivariate analysis found body mass index (BMI) was the strongest risk factor for SSI (OR 1.08[95% CI 1.03 to 1.14] per 1 kg/m2 increase in BMI [p=0.001]). …”
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  7. 70247

    Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

    Published 2023-01-01
    “…Here, in this research, we aim to address the role of CEMIP in mediating MHC-I expression in tumor cells and investigate the underlying regulatory mechanisms.Method Protein levels were analyzed by western blotting. Flow cytometry analysis was used to examine immune cells. Protein–protein interactions were investigated by co-immunoprecipitation and proximity ligation assays. …”
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  8. 70248

    First aid intervention in the adult population: the Yorkshire Health Study and its implications for first aid education

    Published 2018-08-01
    “…Conclusion: Despite the limitations of this study, analysis of this dataset provides a profile of self-defined first aiders in Yorkshire, UK. …”
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  9. 70249

    Dual Clinical Practice (DCP) policy to improve the retention of human resources for health in Rwanda: a mid-term review using a cross-sectional and retrospective study design by Kizito Kayumba, Corneille Ntihabose, Sabine Musange Furere, Bernard Ngabo, Piero Irakiza, Felix K. Rubuga, Nathalie Umutoni, Ina Rukundo Kalisa, Pascal Birindabagabo, Emile Rwamasirabo, Emmanuel Kayibanda, Patience Mukundirukuri, Gashaija Absolomon, Sumana Dhanani, Jeanine Condo

    Published 2025-02-01
    “…Quantitative and qualitative data were collected through key informant interviews (KIIs) and joint interviews (JIs), as well as through the analysis of health facility records obtained from the Health Management Information System (HMIS) and the Electronic Medical Record (EMR). …”
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  10. 70250

    Predicting prognosis using stroke-heart indicator: brain natriuretic peptide in patients with aneurysmal subarachnoid hemorrhage by Jionghao Xue, Jionghao Xue, Fa Lin, Fa Lin, Minghao Liu, Minghao Liu, Wenxiong Song, Wenxiong Song, Runting Li, Runting Li, Yu Chen, Yu Chen, Jun Yang, Jun Yang, Heze Han, Heze Han, Yitong Jia, Yitong Jia, Xiaolin Chen, Xiaolin Chen, Rong Wang, Rong Wang, Yuanli Zhao

    Published 2025-01-01
    “…Additionally, we assessed the potential impact of incorporating BNP into a predictive model for poor prognosis.ResultsThe statistical analysis encompassed a total of 932 patients. Among them, 171 individuals experienced unfavorable prognosis (mRS ≥3) during follow-up, and 444 patients had elevated BNP levels, defined as lgBNP ≥1.79. …”
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  11. 70251

    Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia by Xiaoqian Ma, Nana Feng, Lena Palaniyappan, Luolong Cao, Zixin Gu, Jujiao Kang, Liu Yuan, Lijun Ouyang, Yujue Wang, Chunwang Li, Ke Jin, Xiaogang Chen, Jianfeng Feng, Ying He, Qiang Luo

    Published 2025-01-01
    “…These stratified associations were validated using two large population-based cohorts (the ABCD study; n = 1680, 11.92 ± 0.62 years; and UK Biobank, n = 20547, 55.38 ± 7.43 years). Transcriptomic analysis of brain tissues was used to identify the biological processes associated with the brain mediation effects on the SLE-psychosis relationship. …”
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  12. 70252

    The impact of E × B shear on microtearing based transport in spherical tokamaks by B.S. Patel, M.R. Hardman, D. Kennedy, M. Giacomin, D. Dickinson, C.M. Roach

    Published 2025-01-01
    “…Fusion 51 124020). Bicoherence analysis demonstrates that with the inclusion of E  ×  B shear there is a more effective coupling between the linearly driven drift-waves responsible for transport and zonal modes, which enhances damping. …”
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  13. 70253

    Reference genome provide insights into sex determination of silver aworana (Osteoglossum bicirrhosum) by Yi Liu, Chao Bian, Ka Yan Ma, Yexin Yang, Yuanyuan Wang, Chao Liu, Guochang Ouyang, Meng Xu, Jinhui Sun, Changwei Shao, Jiehu Chen, Qiong Shi, Xidong Mu

    Published 2025-01-01
    “…Furthermore, we found the sex chromosomes to be homomorphic with a potentially recent origin, as a linkage disequilibrium analysis proved minor recombination suppression. Conclusions These results taken together serve as a crucial foundation for conducting extensive investigations on the evolution and differentiation of sex-determining mechanisms, as well as the emergence and development of sex chromosomes in various fishes.…”
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  14. 70254

    Prehospital scale to differentiate intracerebral hemorrhage from large-vessel occlusion patients: a prospective cohort study by A. Freixa-Cruz, G. Jimenez-Jimenez, G. Mauri-Capdevila, Y. Gallego-Sánchez, A. García-Díaz, R. Mitjana-Penella, M. Paul-Arias, C. Pereira-Priego, E. Ruiz-Fernández, S. Salvany-Montserrat, A. Sancho-Saldaña, E. San-Pedro-Murillo, E. Saureu, D. Vázquez-Justes, Francisco Purroy

    Published 2025-01-01
    “…In the multivariate analysis, headache (odds ratio [OR] 3.56; 1.50–8.43), GCS < 8 (OR 8.19; 3.17–21.13), SBP > 160mmHg (OR 6.43; 3.37–12.26) and male sex (OR 2.07; 1.13–3.80) were associated with ICH, while previous hypercholesterolemia (OR 0.35; 0.19–0.65) with LVO. …”
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  15. 70255

    Navigating Emergency Management of Cancer Patients: A Retrospective Study on First-Time, End-Stage, and Other Established Diagnoses in a High Turnover Emergency County Hospital by Mihaela Corlade-Andrei, Radu-Alexandru Iacobescu, Viorica Popa, Alexandra Hauta, Paul Nedelea, Gabriela Grigorasi, Monica Puticiu, Roxana Elena Ciuntu, Andreea Ivona Sova, Diana Cimpoesu

    Published 2025-01-01
    “…The proportion and demographic characteristics of end-stage patients and those who received a first-time diagnosis during the emergency visit were evaluated. Risk analysis was performed to understand these patients’ care needs (such as medical care, surgical care, specialty consults, intensive care, ward admission, and other hospital transfers) and immediate care outcomes (such as in-hospital mortality and home discharge). …”
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  16. 70256

    Hot deformation behavior and dynamic recrystallization kinetic modeling of the Mg–7Gd–3Y–1Zn–0.5Zr alloy by Chen Zhong, Yongjun Li, Qichi Le, Minglong Ma, Xinggang Li, Guoliang Shi, Jiawei Yuan, Zhaoqian Sun, Kui Zhang

    Published 2025-01-01
    “…Combined with the microstructure analysis, it can be found that the Long Period Stacking Ordered (LPSO) phase is able to promote DRX during the hot deformation, but its ability to promote DRX is less pronounced than that of grain boundaries. …”
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  17. 70257

    Faktor Risiko yang Berhubungan dengan Kejadian Pneumonia pada Balita di Kelurahan Air Tawar Barat Padang by Yulia Efni, Rizanda Machmud, Dian Pertiwi

    Published 2016-08-01
    “…</em><em>The result </em><em>of </em><em>biva</em><em>riate </em><em>analysis show</em><em>s </em><em>the </em><em>significant relation</em><em>ship</em><em> between nutritional status</em><em> </em><em>on</em><em> the occurrence </em><em>of pneumonia (p=0</em><em>.…”
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  18. 70258

    Diversity and distribution of nitrifying bacteria play an important role in the nitrogen cycle in mangrove sediments by A. Mubaraq, M. Sembiring, E. Widiastuti, E. Fachrial, B. Utomo, M. Turjaman, F. Sidik, Y.I. Ulumuddin, V.B. Arifanti, E.S. Siregar, T. Kajita, S. Proches, M. Basyuni

    Published 2024-10-01
    “…The primary objective of this study is to provide comprehensive analysis of nitrifying bacteria in mangrove sediments by conducting a systematic review. …”
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  19. 70259

    Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP by Song Guo, Song Guo, Qihao Pan, Qihao Pan, Baokang Chen, Baokang Chen, Yijuan Huang, Yijuan Huang, Si Li, Si Li, Chenyu Gou, Chenyu Gou, Yu Gao, Yu Gao

    Published 2025-01-01
    “…Therefore, this study explored the relationship between trophoblast cell aging and oxidative injury and YAP in AMA pregnancy, which not only provided an insight into the mechanisms of trophoblast cell aging, but also provide valuable directions for healthcare during AMA pregnancy.MethodsIn this study, human term placentas were collected from AMA and normal pregnancies for the analysis of aging, oxidative damage and YAP level. …”
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  20. 70260