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1221
Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses
Published 2024-12-01“…Mycosporine-glycine (M-Gly), a member of the mycosporine-like amino acid (MAA) family, is known for its potent antioxidant and anti-inflammatory properties. …”
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1222
Transcriptome Analysis Revealed the Molecular Mechanism of Acetic Acid Increasing <i>Monascus</i> Pigment Production in <i>Monascus ruber</i> CICC41233
Published 2025-01-01“…The transcriptomics data showed that the differentially expressed genes between <i>M. ruber</i> with acetic acid and without acetic acid were mainly involved in starch and sucrose metabolism, glycolysis/gluconeogenesis, pyruvate metabolism, TCA cycle, and oxidative phosphorylation, and that these differentially expressed genes were not involved in amino acid metabolism. Gene expression analysis showed that the relative expression levels of MP synthesis genes (<i>MpPKS5</i>, <i>MppA</i>, <i>MpFasB</i>, <i>MppB</i>, <i>MppD</i>, and <i>MppR2</i>) were significantly up-regulated under acetic acid conditions. …”
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1223
The study of organelle DNA variability in alloplasmic barley lines in the NGS era
Published 2020-03-01“…Some of the SNPs detected are very similar in codon position and in the type of amino acid substitution to the places where RNA editing can occur. …”
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1224
Analysis of expression and transport activity of sugar transporter gene HpSWEET7 from red pitaya
Published 2025-01-01“…[Results] The ORF of HpSWEET7 was 771 bp, encoding 256 amino acid residues. HpSWEET7 contained two MtN3_saliva (Pfam No. …”
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1225
Effects of supplemental feeding of feeds with different protein levels on the metabolism of the gut microbiota of bighead carp (Hypophthalmichthys nobilis)
Published 2025-03-01“…Overall, the addition of an artificial feed with a protein level of 40 % to traditional culture method promotes the amino acid metabolism in the gut microbiota of bighead carp and improves growth performance. …”
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1226
Plastome data provides new insights into population differentiation and evolution of Ginkgo in the Sichuan Basin of China
Published 2025-01-01“…We identified 170 sequence variants and extensive RNA editing (235 sites) with a bias toward hydrophobic amino acid conversions, suggesting active molecular evolution. …”
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1227
SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation
Published 2025-01-01“…These include enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and neurotransmitter metabolism. …”
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1228
The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001
Published 2020-01-01“…These DEGs included ABC transporters; estrogen-degrading genes, including those that perform initial oxidation and dehydrogenation reactions and those that further degrade the resulting substrates into small molecules; and metabolism genes that complete the intracellular transformation and utilization of estrogen metabolites through biological processes such as amino acid metabolism, lipid metabolism, carbohydrate metabolism, and the tricarboxylic acid cycle. …”
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1229
Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis in Suckling Lambs with Intrauterine Growth Retardation
Published 2020-01-01“…L-arginine (Arg) is a semiessential amino acid with several physiological functions. N-Carbamylglutamate (NCG) can promote the synthesis of endogenous Arg in mammals. …”
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1230
A Novel Mutation in the CYP11B1 Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy
Published 2015-01-01“…The mutation created a premature stop codon at amino acid 260 (p.W260∗), resulting in a truncated protein devoid of 11β-hydroxylase activity. …”
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1231
Chemical, Spectral, Biological, and Toxicological Studies of Some Benzene Derivatives Used in Pharmaceuticals: In Silico Approach
Published 2024-12-01“…Binding affinities and behaviors of all BDs have been investigated using molecular docking and nonbonding interactions on 3D crystal structures of human receptor proteins serum albumin (1AO6), free native cellulase CEL48F (1G9G), and human D-amino acid oxidase mutant (P219L) complexed with benzoate (6KBP). …”
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1232
A soy glycinin derived octapeptide protects against MCD diet induced non-alcoholic fatty liver disease in mice
Published 2022-11-01“…Soy glycinin derived octapeptide (SGP8) is a peptide obtained from degradation of the soy glycinin, whose amino acid sequence is IAVPGEVA. To determine the effect of SGP8 on non-alcoholic fatty liver disease (NAFLD), steatosis HepG2 cells were induced by 1 mmol/L free fatty acid (FFA) and C57BL/6J mice were fed with methionine-choline deficient (MCD) diet for 3 weeks to establish NAFLD model. …”
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1233
Genome-wide identification and expression analysis of the PIN gene family in the pepper pedicel abscission zone and during root development
Published 2024-12-01“…The proteins encoded by these genes exhibit amino acid length ranging from 358 to 654 residues, molecular weight from 39 251.05 D to 71 170.91 D, and isoelectric point from 6.40 to 9.38. …”
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1234
Hypercysteinemia, A Potential Risk Factor for Central Obesity and Related Disorders in Azores, Portugal
Published 2019-01-01“…Hypercysteinemia, which seems to result from sulfur-rich amino acid diets and/or vitamin B12 malabsorption, revealed to be significantly more prevalent in PDL vs. …”
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1235
Systems biology analysis of the WOX5 gene and its functions in the root stem cell niche
Published 2016-09-01“…To this end, we performed a phylogenetic analysis on 62 publicly available WOX5 amino acid sequences, generalized published data about WOX5 expression domain in Arabidopsis and other species and its role in development, integrated the results of experiments on identification of primary and secondary targets for this transcription factor. …”
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1236
Isolation and optimization of Bacillus thuringiensis BRB-3 isolated from germinated black upland rice seeds for GABA production
Published 2025-02-01“…Gamma-aminobutyric acid (GABA) is a non-coded amino acid that recently gained increased attention within the functional food industry. …”
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1237
Molecular Epidemiology of Human Norovirus Variants from Outbreaks in Zhejiang Province, China, during 2021
Published 2024-01-01“…Furthermore, the whole genomes of positive samples were sequenced, enabling the characterization of both nucleotide and amino acid differences within the virus. Finally, phylogenetic trees were constructed to further analyze and understand the genetic relationships among the detected viruses. …”
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1238
The Influence of the Farming System and Forecrop on the Yield and Chemical and Health-Promoting Composition of Spring Wheat Grain
Published 2024-12-01“…Among the forecrops, red clover and sugar beet had the most beneficial effect on grain quality (including the amino acid composition and EAAI index), followed by oat (especially under organic farming conditions). …”
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1239
Transcriptomic Analysis of Pathogenicity Genes in Sclerotinia sclerotiorum Affecting Brassica napus
Published 2024-09-01“…The maximum RSCU was 1.76 for the CCA codon, which encodes the amino acid (aa) proline with a high preference for that codon compared to other synonymous codons of that aa. …”
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1240
Effects of Corneal Stromal Lens Collagen Cross-Linking Regraft on Corneal Biomechanics
Published 2022-01-01“…Corneal collagen cross-linking (CXL) therapy, a method that uses a combination of riboflavin and ultraviolet-A light (UVA), can promote the formation of covalent cross-linking of amino acid residues of corneal collagen and enhance the hardness of the cornea. …”
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