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1121
Genetic tracking of Crimean-Congo haemorrhagic orthonairovirus in Hyalomma population infesting cattle in Nigeria.
Published 2025-01-01“…Additionally, compared to CCHFV isolate IbAr10200 (KY484036), sequences from this study exhibited 9-23 nucleotide variable positions with 3-4 non-synonymous amino acid replacements. Phylogenetic analysis revealed clustering of these strains around IbAr10200, suggesting ongoing circulation. …”
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1122
Polymorphism of the cold receptor gene TRPM8 in native populations of Siberia: putative selective role of rs11563208 polymorphism in Northeast Asia
Published 2017-05-01“…A synonymous substitution at rs11563208 locus may have a functional role because the amino acid residue (isoleucine at position 1016 of TRPM8 protein) corresponding to this locus is located in functionally important TRP-domain and, hence, it can influence thermoreception processes. …”
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1123
Arginine–NO pathway modulated energy metabolism in the hepatopancreas and muscle of female Litopenaeus vannamei
Published 2025-03-01“…The findings showed that the levels of nos, cgmp, ampk (a, b, c), genes involved in glucose metabolism, lipid metabolism and amino acid metabolism were inhibited. In the conclusion, arginine supplementation could promote growth performance through modulating energy metabolism. …”
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1124
From musk to body odor: Decoding olfaction through genetic variation.
Published 2022-02-01“…We noticed that SNPs detected for odor intensity were enriched with amino acid substitutions, implying functional changes of odor receptors. …”
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1125
VARIABILITY OF RACIAL COMPOSITION OF SUNFLOWER BROOMRAPE (ОROBANCHE CUMANA WALLR.) AND NEW STRATEGIES FOR PROTECTION FROM THE PARASITE
Published 2018-05-01“…On the basis of strigolactones, a synthetic preparation, GR24, and its analogues have been created with the aim of introducing them into the soil to stimulate germination of broomrape seeds. The amino acid methionine strongly inhibits the early development of broomrape without a phytotoxic effect in sunflower. …”
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1126
Sequence-based engineering of pH-sensitive antibodies for tumor targeting or endosomal recycling applications
Published 2024-12-01“…SIpHAB, which only requires knowledge of the antibody primary amino-acid sequence, could enable a more efficient triage of pH-sensitive antibody candidates than could be achieved conventionally. …”
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1127
Evaluation of fermented rice bran to replace soybean meal in the diet of Clarias sp. fingerling
Published 2022-09-01“…The results showed that the fermentation of A. niger of 2 % with an incubation period of 24 hours in rice bran resulted in the smallest crude fiber and fraction content, and increased protein and amino acid including serine, threonine, alanine, methionine, isoleucine, and lysine. …”
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1128
The Japanese encephalitis virus NS1' protein facilitates virus infection in mosquitoes.
Published 2025-01-01“…The NS1' protein consists of the full NS1 protein with an additional 52 amino acid extension at the C-terminus and has been demonstrated to exhibit virulence in mammalian hosts upon infection. …”
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1129
A Comparative Study on Growth Performance, Body Composition, and Liver Tissue Metabolism Rearing on Soybean Lecithin-Enriched Artemia Nauplii and Microdiet in Rock Bream (Oplegnath...
Published 2023-01-01“…Larvae fed a MD showed decreased lipolysis-related lipase activity as well as decreased amino acid catabolism-related alanine aminotransferase and aspartate aminotransferase enzyme activities in liver tissue. …”
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1130
Ultrasound-assisted extraction of polyphenols from Lonicera japonica leaves and their α-glucosidase inhibition
Published 2025-01-01“…Fluorescence quenching experiments indicated that the polyphenol extracts interact with α-glucosidase, resulting in alterations to the microenvironment of amino acid residues.DiscussionThis interaction can reduce the binding affinity between the substrate and α-glucosidase, thereby contributing to the objective of lowering postprandial hyperglycemia. …”
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1131
Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales
Published 2024-12-01“…Unexpectedly, trimethoprim did not reduce <i>Wolbachia</i> abundance, and the <i>w</i>Stri DHFR homolog contained amino acid substitutions associated with trimethoprim resistance in <i>E. coli</i>. …”
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1132
Effects of High Dietary Inclusion of Defatted Mealworm (Tenebrio molitor) Meal as a Fish Meal Substitute on Growth, Histological Traits, and Health Performances of Rainbow Trout (O...
Published 2025-01-01“…Based on the results of the second experiment, the apparent digestibility coefficient of dry matter, protein, lipid, energy, and phosphorus were 80%, 87%, 100%, 84%, and 90%, respectively, and all essential amino acid digestibility coefficients were >90%. Overall, the highly digestible DMW can fully replace FM in the diet, up to 40% as fed, with little to no impact on the health, growth performance, feed efficiency, and fillet composition. …”
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1133
Actinorhodopsin: an efficient and robust light-driven proton pump for bionanotechnological applications
Published 2025-02-01“…Here, we characterized the actinorhodopsin RlActR from the freshwater actinobacterium Rhodoluna lacicola, which conserves amino acid residues critical for light-driven proton pumping found in MRs. …”
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1134
Immunization of cattle with a Rhipicephalus microplus chitinase peptide containing predicted B-cell epitopes reduces tick biological fitness
Published 2024-08-01“…First, the predicted amino acid sequence was determined in 4 isolates and their similarity was analysed by bioinformatics. …”
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1135
Inovirus-Encoded Peptides Induce Specific Toxicity in <i>Pseudomonas aeruginosa</i>
Published 2025-01-01“…Through a genomic analysis of the Pf4 prophage, we identified a 102 bp gene co-transcribed with the upstream gene responsible for phage release (<i>zot</i> gene), giving rise to a 33-amino-acid polypeptide that we have named Pf4-encoded toxic polypeptide (PftP4). …”
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1136
Different Metabolites in the Roots, Seeds, and Leaves of Acanthopanax senticosus and Their Role in Alleviating Oxidative Stress
Published 2021-01-01“…Among these, the relative content of flavonoids and terpenoids was found to be highest in the leaves, the lignin and phenolic acid content was highest in the roots, and the amino acid and phenolic acid levels were highest in seeds. …”
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1137
Impact of Enzymatic Degradation Treatment on Physicochemical Properties, Antioxidant Capacity, and Prebiotic Activity of Lilium Polysaccharides
Published 2025-01-01“…Metabolomic analysis revealed that LPSs with varying molecular weights exerted comparable promoting effects on multiple amino acid and carbohydrate metabolic pathways. Importantly, with the reduction in molecular weight, G-LPS(16) also particularly stimulated sphingolipid metabolism, nucleotide metabolism, as well as ascorbic acid and uronic acid metabolism, leading to the significant increase in specific metabolites such as sphingosine. …”
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1138
Understanding the impacts of dual methionine oxidations in complementarity-determining regions on the structure of monoclonal antibodies
Published 2024-12-01“…Moreover, the presence of multiple methionines in close proximity within the amino acid sequence increases the complexity of accurate characterization, and sophisticated analytical methods are required to detect these modifications. …”
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1139
Functional Characterization of Sesquiterpene Synthase from Polygonum minus
Published 2014-01-01“…P. minus sesquiterpene synthase (PmSTS) has a complete open reading frame (ORF) of 1689 base pairs encoding a 562 amino acid protein. Similar to other sesquiterpene synthases, PmSTS has two large domains: the N-terminal domain and the C-terminal metal-binding domain. …”
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1140
Traffic-related air pollution (TRAP) exposure, lung function, airway inflammation and expiratory microbiota: A randomized crossover study
Published 2025-01-01“…Enrichment pathways related to transcription, amino acid and carbohydrate metabolism were altered following high TRAP exposure, suggesting TRAP contributed to the respiratory disease by changing metabolism of lung microbes. …”
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