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1061
Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study
Published 2024-12-01“…Catechin’s inhibitory potential was indicated by negative binding energies and interactions with amino acid residues critical for target protein activity. …”
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1062
Identification and characterization of the COPII vesicle‐forming GTPase Sar1 in Chlamydomonas
Published 2024-06-01“…Here we identified a putative Sar1 homolog (CrSar1) in the model green alga Chlamydomonas reinhardtii through amino acid sequence similarity. We employed site‐directed mutagenesis to generate a dominant‐negative mutant of CrSar1 (CrSar1DN). …”
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1063
The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials
Published 2021-01-01“…Posttranslational modifications are distinct approaches for the adjusted modification of EZH2 in the development of cancer. The amino acid succession of EZH2 protein makes it appropriate for covalent modifications, like phosphorylation, acetylation, O-GlcNAcylation, methylation, ubiquitination, and sumoylation. …”
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1064
Antioxidant and Neuroproliferative Effects of THL-3-PTD5 Peptide Derived from Hydramacin-1 Antimicrobial Peptide
Published 2024-01-01“…Results showed that THL-3 exhibited the strongest antioxidant activity (EC50 of 22.5 μM) in ABTS-radical scavenging assays, with amino acid residues Cys5, Pro6, Leu7, Lys9, and Lys10 playing critical roles in its activity. …”
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1065
Interaction Effects of Tannic Acid and Gluten on Bread-Making and Its Starch Digestion
Published 2025-01-01“…TA strongly interacted with gluten via non-covalent interactions, mainly hydrogen bonds, and formed the major hydrogen bonds with six different glutamines (Q32, Q108, Q313, Q317, Q317, and Q349), which play a critical role in gluten network construction among amino acid residues of gluten. Additionally, TA showed lower binding affinity toward glutenin (−10.4 kcal/mol) compared to gliadin (−8.9 kcal/mol), implying stronger binding with glutenin. …”
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1066
Mitochondrial genome of Cordyceps blackwelliae: organization, transcription, and evolutionary insights into Cordyceps
Published 2023-07-01“…Mitochondrial phylogeny based on either nucleotide or amino acid sequences confirmed the taxonomic position of C. blackwelliae in Cordycipitaceae, clustering together with C. chanhua. …”
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1067
Enhancement of postharvest performance in Lilium tigrinum Ker Gawl flowers with Salicylic acid: a signalling molecule and a growth regulator
Published 2025-02-01“…Furthermore, SA treatment enhances total soluble protein content, increased proline accumulation, decreased specific protease activity and maintained lower amino acid levels. These enhancements in physiological and biochemical stability can significantly enhance the economic viability of the floral industry by extending the postharvest longevity and maintaining the aesthetic integrity of cut flowers, thereby addressing the increasing global demand for superior-quality floral commodities. …”
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1068
Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana.
Published 2025-01-01“…In addition, the C-terminal half of one of the killer proteins is identical to the antidote, and one amino acid, crucial for the antidote activity, is also essential for the killer function. …”
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1069
Antioxidant peptides encrypted in flaxseed proteome: An in silico assessment
Published 2019-09-01“…Most of the APs showed structural features that are important for antioxidation, including relatively low molecular weight (dipeptides and tripeptides only); amphipathic properties (hydrophobicity range of – 0.5 to + 0.5); relatively low Boman index (≤2); broad range of pI (3.7–10.8), and an abundance of antioxidant amino acid residues (e.g. glutamic acid and histidine). …”
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1070
Homology Modeling and Expression of Recombinant NS5-RdRp Based on the Indonesian Local Strain of Dengue Virus for Anti-Dengue Drug Development
Published 2024-09-01“…The resulting RdRp gene sequences are translated into amino acid sequences, which are then used for protein modeling and the construction of a recombinant plasmid for RdRp protein expression. …”
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1071
Two Novel 30K Proteins Overexpressed in Baculovirus System and Their Antiapoptotic Effect in Insect and Mammalian Cells
Published 2013-01-01“…Both Slp and Lsp-t shared more than 41% amino acid sequence homology with the reported 30K proteins and displayed a conserved domain consistent with that of lipoprotein-11. …”
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1072
Regulatory mechanisms tuning ethylen signaling in plants
Published 2016-08-01“…Ethylene biosynthesis from methionine amino acid and the main points of its signaling pathway from membrane receptors to effector genes are studied in details and widely reviewed. …”
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1073
Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition
Published 2025-02-01“…These results suggest that the inhibition of TRE expression may lead to alterations in ovarian nutrient and energy metabolism by modulating glucose transport and affecting amino acid metabolic pathways. These alterations may influence the reproduction of N. lugens by modulating reproductive regulatory signals. …”
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1074
Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sou...
Published 2016-01-01“…The complete MnSR-BI coding sequence was 1545 bp, encoding 514 amino acid peptides. The MnSR-BI primary structure consisted of a CD36 domain that contained two transmembrane regions at the N- and C-terminals of the protein. …”
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1075
Molecular Basis of GABA Hypofunction in Adolescent Schizophrenia-Like Animals
Published 2021-01-01“…Notably, the GABA-related amino acid metabolic process was disturbed in both astrocytes and interneurons, in which we found a downregulated set of GABA-related proteins (GAD65, SYNPR, DBI, GAT3, SN1, and CPT1A). …”
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1076
Screening of Insertion Sites and Tags on EV-A71 VP1 Protein for Recombinant Virus Construction
Published 2025-01-01“…We reported that the site after the 100th amino acid within the VP1 BC loop of EV-A71 is particularly permissive for the insertion of various tags. …”
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1077
Functional Prediction of Hypothetical Proteins from and Validation of the Predicted Models by Using ROC Curve Analysis
Published 2018-12-01“…The genome of Shigella flexneri was extensively analyzed and found 4,362 proteins among which the functions of 674 proteins, termed as hypothetical proteins (HPs) had not been previously elucidated. Amino acid sequences of all these 674 HPs were studied and the functions of a total of 39 HPs have been assigned with high level of confidence. …”
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1078
Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera
Published 2025-01-01“…Abstract The recently detected Omicron BA.2.86 lineage contains more than 30 amino acid mutations relative to BA.2. BA.2.86 and its JN.1 derivative evade neutralization by serum antibodies of fully vaccinated individuals. …”
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1079
Effect of <i>FABP4</i> Gene Polymorphisms on Fatty Acid Composition, Chemical Composition, and Carcass Traits in Sonid Sheep
Published 2025-01-01“…The results of the association study showed that g.57764667T>C, g.57764436T>G, g.57764242G>A, and g.57757988A>G were associated with the composition of certain long-chain FAs, and g.57764242G>A, g.57764436T>G, and g.57758026G>A were associated with free amino acid levels. In addition, g.57764667T>C and g.57757988A>G were associated with carcass weight and live weight in Sonid lambs. …”
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1080
Molecular identification of chitinase and its function in growth of Odontobutis potamophila
Published 2025-03-01“…In this study, a full-length cDNA of chitinase gene (namely, OpCht) was obtained from dark sleeper Odontobutis potamophila. The predicted amino acid sequence of OpCht consisted of a typical catalytic domain and a chitin-binding domain interconnected with a linker region. …”
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