COMPARISON OF THE COMPLETE NUCLEOTIDE SEQUENCES OF MITOCHONDRIAL DNA FROM WISTAR AND OXYS RAT STRAINS MAINTAINED AT THE INSTITUTE OF CYTOLOGY AND GENETICS SB RAS by R. A. Maksyutov, E. V. Gavrilova, T. S. Nepomniashchikh, U. N. Rotskaya, P. S. Loshchenova, N. G. Kolosova, O. I. Sinitsyna, S. N. Shchelkunov

“…It was shown that two additional unique nucleotide substitutions between rats OXYS (ICG) and Wistar (ICG) were absent from other known nucleotide sequences of rat mitochondrial DNA of rats and that they did not cause amino acid substitutions, so that all phenotypic differences between the lines were determined only by differences in their nuclear DNA. …”
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Identification and characterization of a novel tetrapeptide from enzymatic hydrolysates of Baijiu byproduct by Qiang Wu, Changqing Zhong, Guirong Zeng, Xu Zhang, Liping Xiang, Chang Wan, Yougui Yu

“…A superior ACE inhibitory peptide was separated and purified by ultrafiltration and high-performance liquid chromatography (HPLC), and its amino acid sequence was further identified as Gln-Gly-Val-Pro (QGVP) by electrospray mass spectrometry (ESI-MS). …”
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VLE of Carbon Dioxide-Loaded Aqueous Potassium Salt of L-Histidine Solutions as a Green Solvent for Carbon Dioxide Capture: Experimental Data and Modelling by Afaf Syalsabila, Abdulhalim Shah Maulud, Humbul Suleman, Nik Abdul Hadi Md Nordin

“…When compared to conventional solvent (monoethanolamine) and amino acid salt (potassium L-lysinate) at similar process conditions, L-histidine has superior absorption capacity. …”
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Sustainable Ultrasound-Assisted Solid-Phase peptide synthesis (SUS-SPPS): Less Waste, more efficiency by Salvatore Mottola, Alessandra Del Bene, Vincenzo Mazzarella, Roberto Cutolo, Ida Boccino, Francesco Merlino, Sandro Cosconati, Salvatore Di Maro, Anna Messere

“…The first step sequentially combines Fmoc-amino acid coupling, capping of unreacted amino groups, and Fmoc deprotection into a single operation, while the second one consists of a single washing procedure. …”
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An in-depth study of indolone derivatives as potential lung cancer treatment by Mohammed Er-rajy, Mohamed El fadili, Radwan Alnajjar, Sara Zarougui, Somdutt Mujwar, Khalil Azzaoui, Hatem A. Abuelizz, Belkheir Hammouti, Menana Elhallaoui

“…Molecular docking studies of the most active compounds revealed strong interactions with critical amino acid residues in the PDK1 receptor’s binding site, underscoring their potential as effective PDK1 inhibitors. …”
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Regulation of stress granule maturation and dynamics by poly(ADP-ribose) interaction with PARP13 by Shang-Jung Cheng, Temitope Gafaar, Jijin R. A. Kuttiyatveetil, Aleksandr Sverzhinsky, Carla Chen, Minghui Xu, Allison Lilley, John M. Pascal, Anthony K. L. Leung

“…Here, we demonstrate that PAR-mediated interactions through PARP13, specifically the PARP13.2 isoform, are essential for modulating the dynamics of stress granules—a class of cytoplasmic condensates that form upon stress, including types frequently observed in cancers. Single amino acid mutations in PARP13, which reduce its PAR-binding activity, lead to the formation of smaller yet more numerous stress granules than observed in the wild-type. …”
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Validation of a multiplexed immunoassay for immunological analysis of pre erythrocytic malaria vaccines by L. K. Stockdale, S. Provstgaard-Morys, D. Bellamy, D. Woods, K. Rapi, A. Bajer, B. Hollingdale, O. Muñoz, S. Malik, A. V. S. Hill, K. J. Ewer

“…Abstract The primary immunological readout for clinical trials of R21/MatrixM™ malaria vaccine, is total IgG antibody specific to the central four amino acid NANP repeat region of the circumsporozoite protein. …”
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<i>Helicobacter pylori</i> HP0135 Is a Small Lipoprotein That Has a Role in Outer Membrane Stability by Doreen Nguyen, Rachel G. Ivester, Kyle Rosinke, Timothy R. Hoover

“…HP0135 is a small protein, with the mature HP0135 lipoprotein only 28 amino acid residues in length. Deletion of <i>hp0135</i> in <i>H. pylori</i> B128 resulted in morphological abnormalities that included extensive formation of outer membrane vesicles and increased frequency of mini-cells. …”
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Elucidating the degradation mechanism of beef myofibrillar proteins under hydroxyl radical oxidation through the lens of cysteine oxidation modifications by Jiale Li, Jun Liu, Hui Yue, Yuanyuan Ma, He Li, Yuanliang Hu, Xiang Yu, Weiwei Dong, Yanli Feng

“…The Cys of actin (17 Dos), myosin/myomesin (16 Dos), tenascin (12 Dos) and sarcomere (10 Dos) in the MPs structure showed active oxidative modification behavior towards ·OH, especially with the “-C-X-X-X-X-W-” structure amino acid sequence showed high sensitivity. Notably, the oxidative modification of Cys by ·OH was an irreversible process, as evidenced mainly by a significant decrease (p < 0.05) in protein sulfhydryl groups and unfolding of protein secondary and tertiary structures. …”
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Stromal-Cell-Derived Factor-1 (SDF-1)/CXCL12 as Potential Target of Therapeutic Angiogenesis in Critical Leg Ischaemia by Teik K. Ho, X. Shiwen, D. Abraham, J. Tsui, D. Baker

“…The biologic effects of SDF-1 are mediated by chemokine receptor CXCR4, a 352 amino acid rhodopsin-like transmembrane-specific G protein-coupled receptor (GPCR). …”
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Multilevel plasticity and altered glycosylation drive aggressiveness in hypoxic and glucose-deprived bladder cancer cells by Andreia Peixoto, Dylan Ferreira, Andreia Miranda, Marta Relvas-Santos, Rui Freitas, Tim S. Veth, Andreia Brandão, Eduardo Ferreira, Paula Paulo, Marta Cardoso, Cristiana Gaiteiro, Sofia Cotton, Janine Soares, Luís Lima, Filipe Teixeira, Rita Ferreira, Carlos Palmeira, Albert J.R. Heck, Maria José Oliveira, André M.N. Silva, Lúcio Lara Santos, José Alexandre Ferreira

“…Employing a multi-omics approach, we discovered that hypoxic and glucose-deprived cancer cells enter a quiescent state supported by mitophagy, fatty acid β-oxidation, and amino acid catabolism, concurrently enhancing their invasive capabilities. …”
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Dysfunctional BCAA degradation triggers neuronal damage through disrupted AMPK-mitochondrial axis due to enhanced PP2Ac interaction by Shih-Cheng Wu, Yan-Jhen Chen, Shih-Han Su, Pai-Hsiang Fang, Rei-Wen Liu, Hui-Ying Tsai, Yen-Jui Chang, Hsing-Han Li, Jian-Chiuan Li, Chun-Hong Chen

“…Abstract Metabolic and neurological disorders commonly display dysfunctional branched-chain amino acid (BCAA) metabolism, though it is poorly understood how this leads to neurological damage. …”
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High-resolution isotope dietary analysis of Mesolithic and Neolithic humans from Franchthi Cave, Greece. by Valentina Martinoia, Anastasia Papathanasiou, Sahra Talamo, Rebecca MacDonald, Michael P Richards

“…High-resolution compound specific amino acid isotope analysis reported here from humans from the Lower Mesolithic and Middle Neolithic periods confirms the previous bulk isotope results in showing little or no consumption of marine foods in either time period. …”
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Senyawa Fucodiphlorethol Dan Phloroglucinol Alga Coklat Sebagai Inhibitor Lipase Secara In Silico by Yohanes Bare, Dewi Ratih Tirto Sari, Marsiana Coo Mogi, Maria Marcelina Dua Nurak

“…Phloroglucinol - pancreatic lipase showed five amino acid residues by hydrogen bonds, hydrophobic and electrostatic. …”
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Use and legislation of Glyphosate in Mexico: healthcare, healthy environment and drinking water access. by Arizbeth Pérez-Martínez, Arely Vergara-Castañeda, Kytzia Esmeralda Mercado-Moreno, Christian Benítez-Núñez, Alma Cossette Guadarrama Muñoz

“…However, glyphosate inhibits enzymatic production which is the key factor to the aromatic amino acid biosynthesis needed for vegetation growth, having a negative effect on the environment. …”
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Direct coupling analysis and the attention mechanism by Francesco Caredda, Andrea Pagnani

“…For this reason, being able to predict their structure from the amino acid sequence has been and still is a phenomenal computational challenge that the introduction of AlphaFold solved with unprecedented accuracy. …”
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Sarcopenia and Age-Related Endocrine Function by Kunihiro Sakuma, Akihiko Yamaguchi

“…Myostatin inhibition seems to be the most interesting strategy for attenuating sarcopenia other than resistance training with amino acid supplementation. Testosterone supplementation in large amounts and at low frequency improves muscle defects with aging but has several side effects. …”
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Prediction of IL4 Inducing Peptides by Sandeep Kumar Dhanda, Sudheer Gupta, Pooja Vir, G. P. S. Raghava

“…Based on our analysis we developed classification models where the hybrid method of amino acid pairs and motif information performed the best with maximum accuracy of 75.76% and MCC of 0.51. …”
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Composition and functional diversity of soil and water microbial communities in the rice-crab symbiosis system. by Guo Yang, Tian Juncang, Wang Zhi

“…The main functional genes are related to metabolic functions, including secondary product metabolism, energy metabolism, and amino acid metabolism.…”
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Fine-Needle Aspiration Cytology of Parathyroid Carcinoma Mimic Hürthle Cell Thyroid Neoplasm by Chutintorn Sriphrapradang, Pattana Sornmayura, Niramol Chanplakorn, Objoon Trachoo, Pattarana Sae-Chew, Rangsima Aroonroch

“…Genetic analysis found somatic mutation of CDC73 gene in exon1 (c.70delG) which caused premature stop codon in amino acid 26 (p.Glu24Lysfs2*). The final diagnosis was hyperparathyroidism-jaw tumor syndrome. …”
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