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961
Structural Analysis of Amylin and Amyloid β Peptide Signaling in Alzheimer’s Disease
Published 2025-01-01“…Replica exchange molecular dynamics simulation machine learning, as well as other computational analyses, were applied to improve the understanding of the amino acid residues in these amylin-based peptides. …”
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962
Determinants of the Sensory Quality of Półgęsek in Relation to Volatile Compounds and Chemical Composition
Published 2017-12-01“…The typical decomposition products derived from lipid oxidation, amino acid degradation, carbohydrate fermentation and microbial esterification were the main volatiles detected in all the samples. …”
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963
Structural Features and Transcriptional Activity of Chicken PPARs (α, β, and γ)
Published 2013-01-01“…This ligand selectivity relies on one amino acid residue (chicken: Val419, human: Met444). …”
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964
Solid Lipid Nanoparticles Based on L-Cysteine for Progesterone Intravaginal Delivery
Published 2019-01-01“…In particular, the hydroxyl group less sterically encumbered was functionalized with a thiol group, in a coupling reaction, with the amino acid L-cysteine. The obtained compound was characterized by FT-IR spectrometry and 1H-NMR. …”
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965
Application of Metabolomics to Study Effects of Bariatric Surgery
Published 2018-01-01“…Detected changes pertain to amino acid, lipids, carbohydrates, or gut microbiota alterations. …”
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966
Promising role of voxelotor in managing sickle cell disease in children: a narrative review
Published 2025-02-01“…To date, 4 disease-modifying drugs have been approved for the treatment of SCD: hydroxyurea (an S-phase inhibitor), L-glutamine (an amino acid), crizanlizumab (a P-selectin inhibitor), and voxelotor (a hemoglobin S polymerization inhibitor). …”
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967
Angiotensin-Converting Enzyme 2: The First Decade
Published 2012-01-01“…Moreover, investigations focusing on ACE2 have revealed a variety of roles not just catalytic but also as a viral receptor and amino acid transporter. This paper focuses on what is known about ACE2 and its biological roles, paying particular attention to the regulation of ACE2 expression. …”
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968
Rapid and Nondestructive Detection of Proline in Serum Using Near-Infrared Spectroscopy and Partial Least Squares
Published 2022-01-01“…Proline is an important amino acid that widely affects life activities. It plays an important role in the occurrence and development of diseases. …”
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969
False morel poisoning in a cat
Published 2020-09-01“…As a treatment, 0.9% isotonic NaCl (Polyplex, Polifarma®) solutions 40 ml/kg via IV, maropitant (Cerenia, Zoetis®) 1 mg/kg as an antiemetic and to reduce visceral pain via SC, N-acetylcystein (Nacosel, Haver Farma®) 140 mg/kg via IV, vitamins and amino acid supplementation (Duphalyte, Zoetis®) via IV are administered. …”
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970
Arsenic efflux and bioremediation potential of Klebsiella oxytoca via the arsB gene.
Published 2025-01-01“…Fourier transform infrared spectroscopy (FTIR) analysis confirmed interaction of arsenate and arsenite with functional groups (aromatic amino acid residues) on the cell surface leading to characteristic peak shifts. …”
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971
Rare Suprasellar Chordoid Meningioma with INI1 Gene Mutation
Published 2017-09-01“…DNA sequencing showedheterozygosity C-T mutation in exon 9 of INI1 gene leading to change of amino acid serine to phenylalanine at (codon 63). The details of this case are presented with a review of the literature.…”
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972
Homocysteine and Hypertension in Diabetes: Does PPARγ Have a Regulatory Role?
Published 2010-01-01“…Homocysteine, which is a nonprotein amino acid, at elevated levels is an independent cardio-renovascular risk factor. …”
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973
Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
Published 2025-01-01“…Proteinoids, or thermal proteins, are amino acid polymers formed at high temperatures by non-biological processes. …”
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974
Micellization Studies on Binary Mixture of Methionine with Polyoxyethylene (10) Cetyl Ether (Brij-56) and Polyoxyethylene (20) Cetyl Ether (Brij-58)
Published 2010-01-01“…This is mainly due to increased micelle concentrations. The influence of amino acid on the cloud point of Brij-56 and Brij-58 is a clear indication that the phenomenon of clouding is associated with the different micelles coalescing. …”
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975
Cloning and sequencing of VP19-encoding gene of white spot syndrome virus from Situbondo’s isolate
Published 2015-04-01“…However, the sequence result shows that there are some differences on bases and amino acid. However, the result of sequencing shows there are difference of five base and three amino acid arranged VP19 sequence the Situbondo isolate with isolate from several countries. …”
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976
Origins and Evolution of WUSCHEL-Related Homeobox Protein Family in Plant Kingdom
Published 2014-01-01“…Linkage analysis of WOX protein sequences demonstrated that amino acid residues 141–145 and 153–160 located in the homeodomain are possibly associated with the function of WOXs during the evolution. …”
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977
BAC-browser: the tool for synthetic biology
Published 2025-01-01“…It helps to design nucleotide sequences and features the following tools: generate nucleotide sequence from amino acid sequences using a codon frequency table for a specific organism, as well as visualization of restriction sites, GC composition, GC skew and secondary structure. …”
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978
Ammonia-Assimilating Bacteria Promote Wheat (<i>Triticum aestivum</i>) Growth and Nitrogen Utilization
Published 2024-12-01“…The results suggest that the ammonia-assimilating bacterium promotes wheat growth, nitrogen accumulation, and soil nitrogen immobilization by establishing an ammonia and amino acid exchange with roots and enhancing root antioxidant capacity, making it a potential plant growth-promoting rhizobacteria (PGPR).…”
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979
Microwave Irradiation Enhances the Germination Rate of Tartary Buckwheat and Content of Some Compounds in Its Sprouts
Published 2018-09-01“…The exposure at 600 W for 30 s stimulated the total flavones content, reduced the sugar and soluble protein contents, and increased the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity. The highest free amino acid content (11 mg/g) was observed in 5-day sprouts exposed to 800 W for 10 s. …”
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980
Study on Effect of Producing Region on the Metabolome Composition of Rice
Published 2025-01-01“…By principal component analysis (PCA) and partial least square discriminant analysis (OPLS-DA), the results showed that the numbers of differential metabolites between the comparison groups (GJYH290 vs MLYH290, MZYH290 vs GJYH290, MZYH290 vs MLYH290) were 130, 180, and 192, respectively, only 6 different metabolites were common to all three comparison groups, with the main metabolic pathways involving amino acid metabolism and flavonoid metabolism. The top 10 most significantly upregulated and downregulated metabolites with the largest fold changes in the 3 comparison groups were mainly flavonoids, phenolic acids, nucleotides and their derivatives. …”
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